Biochemicals and Reagents

Hemopressin is a synthetic, orally active, insulin-sensitizing agent. Hemopressin modulates the activity of the insulin receptor by binding to the carboxy terminal domain. This leads to increased insulin sensitivity and glucose uptake in peripheral tissues. Hemopressin has been shown to be effective against experimental models of autoimmune diseases, such as diabetes mellitus type 1 and multiple sclerosis. The drug significantly decreased blood pressure in healthy rats and had no effect on cancer cells or bacterial surface.

A synthetic peptide for use as a blocking control in assays to test for specificity of Arpp21 antibody, catalog no. 70R-8517

1-224 amino acids: MGSSHHHHHH SSGLVPRGSH MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPR

CD38 antibody (Allophycocyanin) was raised in rat using CD38 as the immunogen.

Agomelatine (L(+)-tartaric acid) is a synthetic antidepressant, which is derived from chemical synthesis. It acts primarily by serving as an agonist at melatonin MT1 and MT2 receptors and as an antagonist at 5-HT2C serotonin receptors. This dual mechanism of action is particularly significant as it helps regulate sleep-wake cycles and mood by re-establishing normal circadian rhythms.

1-217 amino acids: MSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLS WLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH

MLXIP antibody was raised in Rabbit using Human MLXIP as the immunogen

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC38A3 antibody, catalog no. 70R-7037

A synthetic peptide for use as a blocking control in assays to test for specificity of CPA1 antibody, catalog no. 70R-5489

The SMAD antibody is a highly specific monoclonal antibody that targets the SMAD protein, an important regulator of cellular processes. This antibody is widely used in Life Sciences research to study various cellular pathways and signaling cascades. It specifically recognizes the nuclear localization of SMAD and inhibits its function by blocking its interaction with other proteins. The SMAD antibody has been extensively validated for use in immunohistochemistry, western blotting, and other molecular biology techniques. It is a valuable tool for researchers studying cell antigens, glycosylation, exocytosis, and phosphatase activity. Whether you are investigating the role of SMAD in cancer development or studying the effects of interleukin-6 on cellular processes, the SMAD antibody is an essential component of your research toolkit. Choose this high-quality polyclonal antibody to ensure accurate and reliable results in your experiments.

Iomazenil is a benzodiazepine derivative that has been used as an antidote for benzodiazepine overdose. It binds to the GABA-A receptor and increases the rate of metabolism, which leads to increased blood flow to the brain. Iomazenil also has analytical applications in diagnosing hyperproliferative diseases such as cancer, by measuring the levels of metabolites in urine or blood samples. The drug can be used to measure metabolic rates and the activity index of caudate putamen cells. It also binds to receptors on mononuclear leukocytes and induces an increase in gamma-aminobutyric acid (GABA) production, which leads to cell death.

GSTZ1 antibody was raised in Rabbit using Human GSTZ1 as the immunogen

Valecobulin hydrochloride is a substance that is used to disrupt the formation of malignant tumours. It can be used as an adjuvant treatment for cancer, or in the treatment of liver cancer. Valecobulin hydrochloride has been shown to inhibit the growth of malignant tumours by inhibiting the vessels that supply blood and nutrients to the tumour. It also has immune-modulating properties and can activate macrophages, which are white blood cells that engulf foreign substances. Valecobulin hydrochloride can be used in combination with other medicines such as chemotherapeutic drugs to treat cancer.

Albaspidin AA is an extract of the fructus Dryopteris that has been shown to be effective against influenza viruses. This extract binds to the virus and inhibits its ability to infect cells. Albaspidin AA also has a strong antiviral effect on animals, such as chickens and ducks, which are susceptible to avian influenza. The dryopteris fructus is obtained by extraction with alcohol and water, followed by column chromatography.

Affinity purified Rabbit polyclonal SHKBP1 antibody

HRH1 antibody was raised in Rabbit using Human HRH1 as the immunogen

Rabbit polyclonal TLR2 antibody (N-terminal)

MLT-747 is a high-performance polymer composite, which is a synthetic material derived from advanced polymerization techniques involving specific monomers and additives. Its formulation is designed to provide exceptional mechanical properties and thermal stability through the integration of reinforcing agents and proprietary chemical modifications.

Lenalidomide-acetylene-C5-COOH is a peptide that can be used as a research tool. It has been shown to activate the immune system, and it may be used as an antibody or ligand for receptor binding. Lenalidomide-acetylene-C5-COOH also binds to ion channels and inhibits protein interactions.

N6-Ethyladenosine is a nucleoside analogue drug that interacts with a variety of proteins, including receptors and ion channels. It has high purity and is used as a research tool to study the mechanism of action of drugs. N6-Ethyladenosine has been shown to inhibit ion channels such as potassium channels, and can be used in cell biology to study the effects on receptor activation or ligand binding.

A synthetic peptide for use as a blocking control in assays to test for specificity of Commd2 antibody, catalog no. 70R-9447

Mouse monoclonal RPN1 antibody

The GBA antibody is a polyclonal antibody that specifically targets the primary amino acid sequence of the glucocerebrosidase (GBA) enzyme. This antibody is derived from human serum and has been extensively validated for its specificity and sensitivity. It can be used in various applications, including enzyme-linked immunosorbent assays (ELISAs), Western blotting, and immunohistochemistry.

The CD34 antibody is a highly specialized antibody that targets a specific cell antigen known as CD34. This antibody can be used in various applications within the Life Sciences field, particularly in the study of functional endothelial cells and microvessel density.

CD72.1 antibody (biotin) was raised in mouse using DBA/2 murine spleen cells as the immunogen.

Affinity purified Rabbit polyclonal AMPK gamma 2 antibody

CD32 antibody (Fab'2) was raised in mouse using human K562 tumor cells and L cells tranfected with human Fc gamma RII as the immunogen.

PRT062607 (P505-15) HCl is a small-molecule inhibitor, which is a synthetic compound with a highly specific action on the 3-phosphoinositide-dependent protein kinase-1 (PDK1). This compound is derived through rational drug design processes aimed at modulating intracellular signaling pathways. PRT062607 acts by selectively binding to the ATP-binding site of PDK1, thereby inhibiting its kinase activity. This inhibition disrupts downstream signaling mediated by the phosphoinositide 3-kinase (PI3K) pathway, which is pivotal in regulating various cellular processes, including growth, survival, and metabolism.

The CD107a antibody is a highly effective immunoassay tool used in Life Sciences research. This monoclonal antibody targets the CD107a protein, also known as LAMP-1 (lysosomal-associated membrane protein 1), which plays a crucial role in cell activation and degranulation processes. By binding to CD107a, this antibody allows for the detection and quantification of activated immune cells.

Affinity purified Rabbit polyclonal Glycine dehydrogenase antibody

Procalcitonin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 116 amino acids. Molecular weight is 12.8 kDa.amino acid sequence: APFRSALESS PADPATLSED EARLLLAALV QDYVQMKASE LEQEQEREGS SLDSPRSKRC GNLSTCMLGT YTQDFNKFHT FPQTAIGVGA PGKKRDMSSD LERDHRPHVS MPQNAN

A synthetic peptide for use as a blocking control in assays to test for specificity of C9orf75 antibody, catalog no. 70R-3687

A synthetic peptide for use as a blocking control in assays to test for specificity of CHRND antibody, catalog no. 70R-8065

A synthetic peptide for use as a blocking control in assays to test for specificity of RWDD4A antibody, catalog no. 70R-3398

Affinity purified Rabbit polyclonal MAPK1 antibody

Region of Persephin protein corresponding to amino acids ALAGSCRLWS LTLPVAELGL GYASEEKVIF RYCAGSCPQE ARTQHSLVLA RLRGRGRAHG RPCCQPTSYA DVTFLDDQHH WQQLPQLSAA ACGCGG.

NTRC 824 is an innovative bioactive compound, meticulously developed from natural sources, with unique properties that facilitate its mode of action. The compound is derived through an advanced extraction and purification process ensuring its optimal efficacy and stability. NTRC 824 operates by modulating specific molecular pathways, which are central to its function in targeted applications.

Rabbit polyclonal POLR3A antibody

The HCG beta Antibody is a specific monoclonal antibody that is commonly used in Life Sciences research. It has been extensively studied and proven to be highly effective in various applications. This antibody specifically targets the influenza hemagglutinin, which plays a crucial role in receptor binding and viral entry.

A synthetic peptide for use as a blocking control in assays to test for specificity of RPS21 antibody, catalog no. 70R-2535

CD3e antibody (FITC) was raised in hamster using H-2Kb-specific murine cytotoxic T lymphocyte as the immunogen.

A synthetic peptide for use as a blocking control in assays to test for specificity of MMP13 antibody, catalog no. 70R-5295

Affinity purified Rabbit polyclonal STAM antibody

A synthetic peptide for use as a blocking control in assays to test for specificity of GRK7 antibody, catalog no. 70R-9903

A synthetic peptide for use as a blocking control in assays to test for specificity of ACTL6B antibody, catalog no. 70R-3899

The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is a powerful antituberculosis drug that falls under the class of rifamycins. It is highly effective in treating tuberculosis infections due to its bactericidal activity. This active compound works by binding to DNA-dependent RNA polymerase, which prevents transcription and replication, inhibiting bacterial growth. Extensive research has shown its high activity on human erythrocytes using the patch-clamp technique. The drug undergoes various metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Additionally, it specifically targets markers expressed in Mycobacterium tuberculosis strains and inhibits their cell growth in culture.

NCG31955 is a heterocyclic compound that has been shown to be a potent inhibitor of the cytochrome P450 enzyme, which is involved in the oxidation of aromatic compounds. NCG31955 also has an inhibitory effect on the bacterial enzyme, DNA gyrase. This inhibition prevents the production of dsDNA and prevents cell division. NCG31955 has been shown to have activity against bacteria such as Mycobacterium tuberculosis and Mycobacterium avium complex.

A synthetic peptide for use as a blocking control in assays to test for specificity of CA8 antibody, catalog no. 70R-1122

Ricasetron is a type of serotonin receptor antagonist that is used to prevent nausea and vomiting caused by certain types of chemotherapy, which are known as emetogenic. Ricasetron is an ion-pair reconstituted drug that binds to the 5-HT4 receptor in the gastrointestinal tract. This prevents serotonin from binding to the receptor, preventing nausea and vomiting. Ricasetron has also been shown to decrease appetite, which may be due to its effects on neurokinin-1 (NK1). Ricasetron has been clinically proven for use in patients with cancer who are receiving chemotherapy.
Ricasetron is a type of fatty acid that is used as a chemical structure in various medications. It was first synthesized in 1972 by scientists at Sandoz Pharmaceuticals AG and was patented in 1974.

A synthetic peptide for use as a blocking control in assays to test for specificity of MAPK3 antibody, catalog no. 70R-5573