Biochemicals and Reagents
Subcategories of "Biochemicals and Reagents"
- Biomolecules(98,575 products)
- By Biological Target(100,701 products)
- By Pharmacological Effects(6,937 products)
- Cryopreservatives(21 products)
- Desinfectants and Related Compounds(28 products)
- Hormones(411 products)
- Plant Biology(6,907 products)
- Secondary Metabolites(14,367 products)
Found 130493 products of "Biochemicals and Reagents"
IL 12 Mouse
IL-12 is a heterodimeric cytokine that can be produced by T cells and natural killer cells. IL-12 is composed of two subunits, p35 and p40. It has been shown to induce the production of Interferon-gamma (IFN-γ) and other cytokines in response to infection with intracellular bacteria, such as Mycobacterium tuberculosis and M. avium complex. IL 12 Mouse is an antibody against the protein IL 12 that blocks its interaction with cell surface receptors on T cells, thus preventing the activation of these cells.Purity:Min. 95%TM-25659
CAS:TM-25659 is a small molecule that inhibits the growth of cancer cells by interfering with signal pathways in the cell. TM-25659 has been shown to inhibit the localization of fetal bovine serum (FBS) in osteogenic genes, which may be due to its effect on growth factor-β1. This drug also has an inhibitory effect on the polymerase chain reaction (PCR), which is important for gene expression regulation. TM-25659 binds to monoclonal antibodies that are specific for growth factors, inactivating them and preventing their binding to receptors on the surface of cells, thus inhibiting their effects. In addition, TM-25659 has anti-inflammatory properties and can be used as a treatment for rheumatoid arthritis or other inflammatory diseases.
Formula:C30H28N8Purity:Min. 95%Molecular weight:500.6 g/molCP-724714
CAS:CP-724714 is a small molecule that is able to inhibit the growth of cancer cells. It has been shown to be effective against HER2+ breast cancer, colorectal carcinoma cell lines, and lung carcinoma cell lines. CP-724714 causes cell cycle arrest by inhibiting the production of proteins required for DNA replication and repair. Cell proliferation inhibition can also be achieved by blocking epidermal growth factor receptors or other growth factors such as platelet-derived growth factor (PDGF). The mechanism of action may involve interference with the activation of protein kinase B (PKB), which is involved in cell signaling pathways. CP-724714 has been studied in both cell culture and clinical studies for its biological function as a cancer therapeutic agent.Formula:C27H27N5O3Purity:Min. 95%Molecular weight:469.53 g/molMK-6892
CAS:MK-6892 is a β-lactamase inhibitor that has been shown to be effective in the treatment of skin infections. It has been shown to inhibit transduction pathways by binding to β-lactamase and preventing it from hydrolyzing β-lactams, thereby increasing the activity of β-lactams. MK-6892 also inhibits receptor activities and kinetics, making it an excellent candidate for use in diagnosis. The drug has been shown to have affinity for lipoproteins and dyslipidemia, as well as ancillary effects on body fluid composition.Formula:C19H22N4O5Purity:Min. 95%Molecular weight:386.4 g/molPNU-177864
CAS:PNU-177864 is a peptide that inhibits the activity of the Kv1.3 channel, which is an ion channel that regulates potassium ion flow across the cell membrane. This inhibition has been shown to reduce the release of neurotransmitters such as glutamate and glycine, which are thought to be involved in the development of chronic pain. PNU-177864 has also been shown to activate a number of receptors, including opioid receptors and serotonin receptors. The receptor activation leads to inhibition of protein synthesis and cellular proliferation.Formula:C18H22ClF3N2O3SPurity:Min. 95%Molecular weight:438.9 g/mol(αS)-α-[(Cyclopropylcarbonyl)amino]-N-[5-[[(1,1-dimethylethyl)amino]sulfonyl]-1-naphthalenyl]benzenepropanamide
CAS:Cyclopropyl-N-[[1-[(5-aminosulfonyl)naphthalen-2-yl]ethyl]amino]-α-(1,1-dimethylethyl)benzenepropanamide is a peptide that has been shown to activate the receptor for Substance P, a neuropeptide involved in pain transmission. Cyclopropyl-N-[[1-[(5-aminosulfonyl)naphthalen-2-yl]ethyl]amino]-α-(1,1-dimethylethyl)benzenepropanamide has also been shown to inhibit ligand binding to Substance P receptors with high affinity.Formula:C27H31N3O4SPurity:Min. 95%Molecular weight:493.62 g/molBMP 2 Human, Monomer
BMP 2 is a member of the TGF-β superfamily and is a potent activator of bone morphogenetic protein receptors. It is a ligand for type I and II receptor complexes. BMPs play a crucial role in embryonic development, tissue repair, and maintenance of cartilage. BMP 2 has been shown to inhibit ion channels such as calcium-activated potassium channels. It also inhibits protein synthesis by inhibiting the activation of transcription factors like CREB, c-Jun N-terminal kinase (JNK), and p38 mitogen activated protein kinase (MAPK). BMP 2 also binds to antibodies that are specific for phosphorylated receptor tyrosine residues, which can be used as research tools in immunohistochemistry experiments or other applications.Purity:Min. 95%GR 103691
CAS:GR 103691 is a neuroprotective drug that modulates the activity of the dopamine receptor. It has been shown to protect tubule cells from damage when they are exposed to toxic levels of dopamine in vitro. GR 103691 also protects animals against the symptoms of Parkinson’s disease. This drug inhibits 5-HT1A receptors, which may provide its neuroprotective effect. GR 103691 has also been found to have an inhibitory effect on renal proximal cells and locomotor activity in animals with nervous system diseases, as well as cancer cell culture.Formula:C30H35N3O3Purity:Min. 95%Molecular weight:485.62 g/molA 410099.1
CAS:A 410099.1 is a research tool that has been shown to be an activator of the ligand receptor, which can be used to study cell biology and pharmacology. It can also be used as an inhibitor of ion channels and protein interactions. A 410099.1 is a high purity peptide that is suitable for use in life science research, such as antibody production, or as a pharmacological tool to study protein interactions.Formula:C27H41ClN4O3Purity:Min. 95%Molecular weight:505.1 g/molLeptin (Mouse)-ELISA Kit (1ea)
Leptin (Mouse)-ELISA Kit is a ready-to-use assay kit for the quantitative determination of mouse leptin in serum, plasma, and cell culture supernatants. The assay is based on a sandwich ELISA using monoclonal antibodies to mouse leptin. This kit provides a simple and accurate method for the detection of mouse leptin in biological samples.Purity:Min. 95%EBE-A 22
CAS:EBE-A 22 is a tyrosine kinase inhibitor that binds to the ATP-binding site of the enzyme and prevents it from transferring phosphate groups. It is orally active and has been shown to inhibit tumor growth in mice with Ewing sarcoma, myeloma cell lines, and squamous carcinomas. EBE-A 22 has also been shown to inhibit tyrosine kinase activity, leading to decreased proliferation of various cells and inhibition of ribosome synthesis. This drug also inhibits receptor activity by binding to the ATP-binding site on the receptor, preventing it from eliciting a cellular response.Formula:C17H16BrN3O2Purity:Min. 95%Molecular weight:374.23 g/molRopivacaine-d7 hydrochloride
CAS:Controlled ProductRopivacaine-d7 hydrochloride is a high purity, research tool for the study of protein interactions. This product is an antagonist of the N-methyl-D-aspartate (NMDA) receptor, and is a ligand for the nicotinic acetylcholine receptors (AChR). Ropivacaine-d7 hydrochloride has been shown to inhibit ion channels such as voltage gated sodium channels and calcium channels. It also blocks ligand binding to AChRs, which may be useful in developing new drugs for the treatment of pain.Formula:C17H27ClN2OPurity:Min. 95%Molecular weight:317.9 g/molBufotalidin
CAS:Bufotalidin is a caffeic acid derivative that has been shown to have inhibitory properties on the heart and locomotor activity. Bufotalidin was shown to decrease the cardiac contractility of isolated rat hearts by inhibiting calcium influx. It also inhibits basic protein kinase C (PKC) in HL-60 cells, which may be due to its ability to inhibit PKC translocation from the cytosol to the membrane. Bufotalidin also has an inhibitory effect on autophagy, which is a process that breaks down cellular components. The molecular mechanisms underlying these effects are not yet understood.Formula:C24H32O6Purity:Min. 95%Molecular weight:416.51 g/molLY3177833
CAS:LY3177833 is a protein kinase inhibitor that binds to the ATP-binding pocket of the enzyme, inhibiting its function. LY3177833 has been shown to be effective against colon cancer cells and has been used in clinical trials. The drug was well-tolerated by patients and had no significant side effects. The efficacy of LY3177833 was demonstrated in vitro, where it inhibited the growth of colon cancer cells with an IC50 of 3 nM at 24 hours. LY3177833 also showed anti-tumor effects in a mouse xenograft model, blocking tumor growth and reducing the number of metastases. In addition, LY3177833 inhibits cellular senescence by inhibiting production of β-galactosidase enzymes and the expression of cancer-related genes.
Formula:C16H12FN5OPurity:Min. 95%Molecular weight:309.3 g/molBRD32048
CAS:BRD32048 is a small molecule that inhibits the activity of oncoproteins and has been shown to have cytotoxic effects against glioma cells. BRD32048 is an acetylated compound, which is able to inhibit the activation or modulate the biological function of molecules by binding to their acetylation sites. This drug can be used as a pharmacological and cancer chemotherapeutic agent for pediatric patients with genetically-defined cancers. BRD32048 has been shown to block prometaphase and hyperproliferation in tumor cells, which may lead to tumor regression.Formula:C16H22N6OPurity:Min. 95%Molecular weight:314.39 g/molC-Peptide I (Mouse)-EIA Kit (1ea)
C-Peptide I (Mouse)-EIA Kit is a mouse monoclonal antibody specific to the C-terminus of human proinsulin. It is used in ELISA as a sandwich reagent.Purity:Min. 95%ent-Niraparib
CAS:Ent-Niraparib is an inhibitor of ion channels and a research tool that binds to the extracellular domain of Ligand Receptor. It is used in Pharmacology as a research tool, and has been shown to be an activator of Ion Channels and a high purity inhibitor of receptor. Ent-Niraparib can also act as an inhibitor of peptide production by binding to ribosomes and preventing protein synthesis, which may lead to death.Formula:C19H20N4OPurity:Min. 95%Molecular weight:320.39 g/molα-Lapachone
CAS:α-Lapachone is a synthetic analog of lapachol. It binds to topoisomerase, which prevents the enzyme from cutting and separating the two strands of DNA. This inhibition causes DNA damage that leads to cell death by necrosis or apoptosis. α-Lapachone also has anticancer activity against murine leukemia cells in culture. α-Lapachone exhibits low cytotoxicity and does not affect healthy cells in culture.
Formula:C15H14O3Purity:Min. 95%Molecular weight:242.27 g/molBAY-1436032
CAS:BAY-1436032 is a novel small molecule inhibitor of CXCR4. It has been shown to be an effective treatment for cancer in vitro, with potent inhibition of cancer cell growth and anti-leukemic activity. BAY-1436032 is orally bioavailable and has good pharmacokinetic properties. It binds specifically to the CXCR4 receptor, blocking the binding of stromal cell-derived factor 1α (SDF1α) and its chemokine ligand 4 (CXCL4). This drug has also been shown to inhibit the proliferation of leukemia stem cells in vitro and in vivo, as well as suppressing sarcoma cell growth.
Formula:C26H30F3N3O3Purity:Min. 95%Molecular weight:489.53 g/molNucleozin
CAS:Nucleozin is an antiviral agent that inhibits the replication of a virus by binding to its nucleic acid. It has been shown to inhibit influenza and other viruses including HIV, hepatitis B, and herpes simplex. Nucleozin is also known as an analog of tryptophan and forms a complex with RNA polymerase or DNA polymerase, which inhibits viral replication. This drug is incompatible with antimicrobial agents such as penicillin and chloramphenicol due to its chemical structure.Formula:C21H19ClN4O4Purity:Min. 95%Molecular weight:426.85 g/mol
