Heterocycles with Nitrogen (N)

<p>Please enquire for more information about 2-Hydroxy-5-nitro-3-(trifluoromethyl)pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-[Chloro(4-chlorophenyl)methyl]-pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-alpha-Fmoc-beta-(1-boc-piperidin-4-yl)-dl-alanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Cbz-(R)-2-methylpiperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Chloro-5-iodopyridine is a synthetic compound that binds to nicotinic acetylcholine receptors, and is an agonist of these receptors. It has been shown to bind selectively to the alpha4beta2 subtype of these receptors. 2-Chloro-5-iodopyridine binds to the receptor by means of hydrogen bonding and chelation, which results in the activation of the receptor. This process leads to increased levels of catecholamines and other neurotransmitters, which causes changes in the heart rate and blood pressure. 2-Chloro-5-iodopyridine is a halogenated organic molecule that can be synthesized from sodium trifluoroacetate in two steps: first with chlorination followed by iodination. The synthesis can be carried out using copper (II) chloride as a catalyst or copper (I) iodide as an oxidant, followed by reduction with sodium borohydride.</p>

<p>Please enquire for more information about 5-Bromo-2-hydroxy-3-methyl pyrazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Bromoimidazo[1,2-b]pyridazine (BIPM) is an analog of etoposide and has been shown to be a potent inhibitor of tyrosine kinases. BIPM selectively inhibits the activity of multikinase enzymes such as c-kit, PDGFRβ, and VEGFR2. In addition, BIPM has been shown to inhibit the proliferation of cancer cells by inducing apoptosis and cell cycle arrest in mcf-7 cells. This drug is not toxic to normal cells and shows a favorable safety profile when tested on animals.</p>

<p>5-Bromo-2-(methylthio)pyrimidine is a synthetic compound that has been used to synthesize palladium complexes. It can also be used in the synthesis of vitamin B1, which is an essential nutrient for humans and animals. 5-Bromo-2-(methylthio)pyrimidine binds with magnesium and reacts with sulfoxide, nucleophilic attack and electronegativity. 5-Bromo-2-(methylthio)pyrimidine is activated by 2-chlorobenzothiazole and hydrogen chloride, which leads to nucleophilic attack on the electrophilic carbon atom. This causes a displacement reaction with the elimination of chlorine gas and production of dihydro.</p>

<p>2-Amino-4-bromopyridine is a potent, selective antagonist of the nicotinic acetylcholine receptor (nAChR) that has been shown to inhibit the proliferation of cancer cells in vitro. 2-Amino-4-bromopyridine binds to the nAChR and stabilizes it by binding to an allosteric site on the receptor. 2-Amino-4-bromopyridine is synthesized from 4,5-dibromobenzene and 2,6-diaminopyridine in two steps with a yield of 47%. The synthesis of 2-amino-4-bromopyridine proceeds via reaction mechanism involving electrophilic substitution at the bromine atom followed by nucleophilic addition at the nitrogen atom.</p>

<p>Please enquire for more information about 3,5-Dichloropyrazine-2-carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.</p>

<p>Please enquire for more information about 5-Bromo-2-dimethylaminopyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about N-[5-(4-Bromophenyl)-6-(2-hydroxyethoxy)-4-pyrimidinyl]-N′-propylsulfamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,4-Dichloropyrido [2,3-D] pyrimidine is a regioselective chlorination agent that can be used for the synthesis of various organic compounds. It is often used in cross-coupling reactions to form carbon-carbon bonds. 2,4-Dichloropyrido [2,3-D] pyrimidine has been shown to give high yields and is selective for disubstituted or monosubstituted substrates. This compound is also useful for the functionalization of C-H bonds via palladium-catalyzed coupling reactions.</p>

<p>4-Chloro-3-nitroquinoline is a quinoline derivative that can be synthesized by cross-coupling reaction. The amide and n-oxide functional groups are the most reactive sites. It can react with nucleophiles such as haloamines, azides, and pyridazines to form covalent bonds. 4-Chloro-3-nitroquinoline has been shown to have anti-HIV activity in vitro and in vivo in animal models. In addition, this compound has shown potential use for the treatment of leishmania.</p>

<p>Sulfamethoxypyridazine is a sulfa drug that inhibits bacterial growth by inhibiting the synthesis of folic acid, which is essential for DNA and RNA production. It has been shown to be effective in the treatment of urinary infections and infectious diseases. Sulfamethoxypyridazine interacts with other drugs, such as oral contraceptives, to increase their blood levels. This drug also has a matrix effect on urine samples, which can be used to detect the presence of bacteria. The matrix effect is due to its hydrophobic nature and ability to form aggregates with other compounds. Sulfamethoxypyridazine is used in wastewater treatment plants as an analytical method for nitrogen atoms.</p>

<p>4-Hydroxy-6-mercaptopyrazolo[3,4-d]pyrimidine is a pyrimidine compound that is a competitive inhibitor of xanthine oxidase (XO) with an IC50 of 0.5 μM. It binds reversibly to the XO enzyme and reverses the effect of the enzyme, thereby inhibiting the production of uric acid. 4-Hydroxy-6-mercaptopyrazolo[3,4-d]pyrimidine does not bind to any other enzymes in the body or affect serum protein levels, which makes it an ideal drug for patients with gout who are at risk for developing renal failure. The drug has been shown to be effective in animal models and is currently undergoing clinical trials in humans.</p>

<p>5-Bromo-2-nitropyridine is a hydrogen bond donor. It is an organic molecule with the chemical formula C5H5BrN3. The compound has been used in the synthesis of other molecules, such as nicotinic acetylcholine and mitochondrial membrane potential inhibitors. 5-Bromo-2-nitropyridine is also a good candidate for cancer treatment due to its ability to inhibit cell cycle progression at G2/M phase. 5-Bromo-2-nitropyridine can be synthesized by reacting 2,4,6-trinitrobenzenesulfonic acid with bromine and potassium carbonate in a reaction vessel at 200 °C for about 30 minutes.</p>

<p>2-Chloropyridin-4-yl)methanamine is a hydrogenated molecule that has been shown to inhibit the activity of certain cancer cells. It inhibits the expression of the enzyme molecules involved in the synthesis of DNA and RNA. 2-Chloropyridin-4-yl)methanamine also inhibits the hydrolysis of hydrogen chloride (HCl) to produce hydrogen (H2). This drug is used as an inhibitor for medicines that require acidic pH for absorption, such as HCl.</p>

<p>Metal-chelating agent</p>

<p>4-Amino-3-hydroxypyridine is a cholinergic drug that has a dose-proportional profile. This drug has been shown to be clinically relevant in humans, and the clinical studies have demonstrated a clear pharmacokinetic profile. 4-Amino-3-hydroxypyridine is metabolized by carbamic acid to form an active metabolite, which binds acetylcholine receptors on cells. This binding results in increased levels of acetylcholine, which can lead to muscle contraction. The drug also inhibits plasma concentrations of other drugs such as warfarin and phenytoin, which may lead to adverse effects or reduced therapeutic efficacy. 4-Amino-3-hydroxypyridine also has functional groups that make it soluble in water and able to cross the blood–brain barrier. In cell culture experiments, 4-amino-3-hydroxypyridine inhibited the growth of rat striatal neurons.</p>

<p>1-Acetylpiperidine-4-carboxylic acid (ACPC) is a synthetic compound that has been shown to be a potent inhibitor of the neurokinin-1 receptor. ACPC has been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. It has also been shown to have antipsychotic effects and could be an effective treatment for psychotic disorders. The pharmacophore of ACPC is based on the cyclohexane ring and piperidine moieties, which are thought to provide affinity for the neurokinin-1 receptor.</p>

<p>2-Methylpyridine-4-boronic acid is a reactive molecule that has been used in post-column derivatization and vivo studies. It has been shown to be reactive with mass spectrometric analysis, cancer assays, proteomics, and tumorigenic sample preparation. It also has been shown to have a molecular target of the cytochrome P450 reductase (CPR), which is involved in the metabolism of drugs and other xenobiotics. 2-Methylpyridine-4-boronic acid binds to CPR and inhibits its enzymatic activity, thereby affecting the metabolism of xenobiotics.</p>

<p>4-Amino-N-(4-methylpyrimidin-2-yl)benzenesulfonamide (AMBPS) is a sulfonamide antimicrobial agent that belongs to the group of sulfa drugs. It is a potent inhibitor of tetracycline resistance in bacterial cells, and has been shown to be effective against infectious diseases such as tuberculosis, leprosy and pneumonia. AMBPS has also been used in wastewater treatment and biological studies with high values. This drug binds to sulfamerazine, which inhibits bacterial growth by inhibiting RNA synthesis. The hydrogen bonding interactions between AMBPS and sulfadiazine are thought to be responsible for the effects on congestive heart failure.</p>

<p>3-Bromopyridazine is a dechlorinated derivative of pyridazine that has been used as an agrochemical. 3-Bromopyridazine can be synthesized by aminocarbonylation at the 3-position, which is a nucleophilic substitution reaction. It has been shown to yield high yields and to react with nucleophiles such as chlorine or heterocycles such as cinnoline. 3-Bromopyridazine can also be obtained by cross coupling of 2-bromoacetophenone with benzaldehyde and pyridine in the presence of copper. The resulting product is then reacted with sodium nitrite in hydrochloric acid to produce 3-bromopyridazine. This compound may have potential use as a chemical intermediate for other compounds, due to its chemical stability and its ability to undergo cross coupling reactions.</p>

<p>2,4-Dimethyl-3-hydroxypyridine is a hydroxypyridine compound with epoxide. It inhibits cytochrome P450 enzymes and is used as an organic solvent. 2,4-Dimethyl-3-hydroxypyridine is also used in research to study the structure of the pyridine ring and the hydroxyl group.</p>

<p>Please enquire for more information about Domperidone N-oxide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about [4,4'-Di-t-butyl-2,2'-bipyridine][bis[5-(t-butyl)-2-[4-(t-butyl)-2-pyridinyl-kN]phenyl-kC]iridium(III) hexafluorophosphate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-[2-(Fmoc-amino)ethyl]-1-piperazineacetic acid dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Bromo-4-nitropyridine is a pyridine compound that has been identified as an environmental contaminant. It is used to synthesize other compounds, such as 4-(3-bromopyridin-2-yl)morpholine, which is used in the synthesis of acetonitrile. 3-Bromo-4-nitropyridine undergoes nucleophilic substitution reactions with amines, leading to homoconjugation and bond cleavage. This reaction may be followed by nitration to give 3-(3'-nitro)pyridine. 3-Bromo-4-nitropyridine can be converted into its n-oxide form or into the ionic form by treatment with acetonitrile.</p>

<p>Please enquire for more information about 5-Bromothieno[2,3-b]pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Bromo-6-methylpicolinic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Piperidylformylaminomethyl resin (200-400 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-[(4-Chlorophenyl)phenylmethyl]-1-piperazineethanol dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Amino-4-hydroxypyridine (2AH) is a synthetic, isomeric compound that has been synthesized in two different forms: 3-bromo-5-hydroxypyridine and hydroxy group. 2AH has been shown to be chemically stable at room temperature and pH levels of less than 7. It also withstands the loss of membrane fluidity induced by amides, such as 3-amino-2-bromopyridine. 2AH can be used to synthesize oxindole derivatives, which are found in natural gas, and piperidines. This chemical can also be used for aminations with pyrrole or 2 amino 4 hydroxypyridine.</p>

<p>4-((5-Bromopyridin-2-yl)amino)-4-oxobutanoic acid (BABA) is a potent photosynthetic inhibitor that inhibits light-driven electron transport in chloroplasts. This inhibition of electron transport leads to the accumulation of reactive oxygen species and cellular dysfunction. BABA is used to induce dormancy in plants and is also used as a chemical inhibitor for arabidopsis thaliana, a type of plant commonly used in molecular biology research. Studies have shown that BABA inhibits the growth of fat cells, which may be due to its ability to inhibit protein synthesis, leading to decreased fat deposition. In addition, this drug has been shown to reduce eye disorders such as retinal degeneration and cataracts by inhibiting the production of reactive oxygen species, which causes oxidative stress.</p>

<p>Please enquire for more information about 6-Bromo-4-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-chloro-3-fluoropyridin-4-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Desloratadine N-hydroxypiperidine is a drug that is used to treat allergic rhinitis and urticaria. It belongs to the class of antihistamines, which block the activity of histamine in the body. Desloratadine N-hydroxypiperidine is a prodrug that has a piperidine moiety attached to its side chain. This prodrug is metabolized into desloratadine, its active form, by esterase enzymes in the liver and blood plasma. The onset of action is rapid after oral administration and the duration of action is 12 hours or more. Desloratadine N-hydroxypiperidine has shown linearity over a wide range of pH values (pH 1 to 10) and ionic strengths (0.1 M to 0.5 M). Optimization was achieved by adjusting elution time, ion-pairing agent, mobile phase composition, organic modifier concentration and column particle</p>

<p>2,3-Difluoro-5-(trifluoromethyl)pyridine is a diluent that is used in organic synthesis. It is a nucleophilic and hydrogen fluoride (HF) activated fluoropyridine. This compound has a diameter of 190.7 pm and an anhydrous form. 2,3-Difluoro-5-(trifluoromethyl)pyridine can be prepared by condensing pyridine with fluorine gas in the presence of an activating agent such as HF or silver nitrate. This compound reacts when exposed to vapor or heat, releasing HF as a byproduct. The pyridine ring found in this compound contains six carbon atoms, two nitrogen atoms, and one oxygen atom.</p>

<p>4-Amino-3-methoxypyridine (4AMMP) is a naturally occurring amino acid that can be found in the nuclei of innervated tissues. It is an inhibitor of the enzyme tyrosine hydroxylase and inhibits the synthesis of catecholamines. The concentration of 4AMMP in blood was measured by radioactivity. This agent has been used for studies on the thalamic nucleus and cortex, as well as for measuring catecholamine levels in tissue homogenates.</p>

<p>2,3-Pyridinedicarboxylic acid dimethylester (PDDE) is a methylated derivative of 3-nitrophthalic anhydride. It has been shown to be a stereoselective receptor blocker that binds to the glutamate site of the N-methyl-D-aspartate receptor. PDDE has also been shown to have high affinity for the cerebral cortex and is able to penetrate the blood brain barrier. PDDE blocks the NMDA receptor by binding to it and preventing ion flow, which leads to inhibition of neurotransmitter release. This drug is used as an injectable methyl derivative with a molecule weight of 217. The ionization detector can detect PDDE in tetrahydrofuran at concentrations of 1,000 ng/mL or less.</p>

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<p>Please enquire for more information about tert-Butyl6-[(1e)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-di oxane-4-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Pyrimidinemethanol is a pyrimidine derivative that is used as a starting material for the synthesis of other compounds. 2-Pyrimidinemethanol is introduced into the body through the skin, lungs and gastrointestinal tract. It has been shown to cause sensitization in humans and rats, with photoexcitation being an important factor in its activity. 2-Pyrimidinemethanol binds to DNA and inhibits protein synthesis by inhibiting ribonucleotide reductase (RNR). The active site of this enzyme contains iron, which is why this compound may be toxic to humans.</p>

<p>2-Bromo-6-methylpyridin-3-ol is a heterocyclic organic compound. It is a pyridine ring with two methyl groups attached to the ring at positions 2 and 6. The bromine atom is at position 3. This is an important intermediate in the Suzuki coupling reaction, which uses it as a starting material for the synthesis of many other compounds. The dieckmann condensation reaction produces this compound from 2,6-dichloropyridine and other reagents. Fluorescent when exposed to UV light, this compound has been used as a probe for chloride ions in solution using mass spectroscopy. This substance also yields dieckmann condensation products with alkynes and chlorine or bromine. 2-Bromo-6-methylpyridin-3-ol can be produced by treating pyridine with methylacrylate in the presence of catalysts such as copper(II)</p>

<p>2,4-Diamino-5-nitropyrimidine is a synthetic molecule that belongs to the class of heterocyclic amines. It has been shown to be a potent antiproliferative agent and has been found to inhibit hepg2 cell growth in vitro. This compound was also found to inhibit cancer cells, including mcf-7. 2,4-Diamino-5-nitropyrimidine binds nucleophilic sites on proteins and inhibits enzymes involved in DNA synthesis. The inhibition of these enzymes leads to cell death by preventing the production of new proteins needed for cell division.</p>

<p>Please enquire for more information about Methyl 4-(3-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-amino-2-mercaptopyrimidine-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Imidazole methyl carboxylate is a drug that inhibits the activity of dehydrogenases and other enzymes. It has been shown to be an inhibitor of the enzyme catalase in vitro and in vivo, which may be due to its ability to bind bidentately with the active site. 4-Imidazole methyl carboxylate is effective when administered orally, and it has been shown to improve symptoms of neurodegenerative diseases such as Alzheimer's disease. This drug also has a trifunctional chemical structure that contains a macrocyclic ring system with an imidazole group and a carboxylic acid group. The redox potential of this molecule makes it suitable for use as an antioxidant.</p>