Building Blocks

<p>Versatile small molecule scaffold</p>

<p>(3-Cyanophenoxy)acetic acid is an analog of mandelic acid that has been shown to inhibit thrombus formation in vitro. The mechanism of action is not well understood, but it may involve the inhibition of phospholipase A2, which inhibits the production of prostaglandin E2 and thromboxane A2. It also inhibits platelet aggregation, the process by which platelets stick together and form clots that can block blood vessels. Furthermore, this compound has been shown to have antithrombotic effects in vivo in mice and rats. (3-Cyanophenoxy)acetic acid does not cause bleeding or increase the risk for bleeding.</p>

<p>4-tert-Butylpiperidine is an organic chemical compound that is a colorless liquid with a strong, unpleasant odor. 4-tert-Butylpiperidine is a nonselective, nucleophilic sulfoxide oxidant that reacts with the electron pair of a sulfur atom in sulfoxides and halides to form alkylating products. It has been used in the oxidation of toluene to benzoic acid and in the synthesis of piperazine. 4-tert-Butylpiperidine can also be used to chlorinate aluminium or as an analytical reagent for the detection of chloride ions. The chemical structure includes two isomeric forms, namely alpha and beta. Alpha is more stable than beta and will react faster; however, beta can be isolated from mixtures of the two compounds by distillation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromopropanedinitrile is an organic solvent that is used as a reactant in the production of polyurethane. It has been shown to have antibacterial activity against a number of bacteria, including Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Proteus vulgaris. 2-Bromopropanedinitrile exhibits its antimicrobial effect by reacting with the chloride ion and nucleophilic attack on the carbonyl group. This reaction causes the chemical to polymerize and form cross-links between molecules of DNA. The compound also has antifungal properties, which may be due to its hydroxyl groups or hydrogenated side chains.</p>

<p>2-Amino-6-methylbenzamide (2AMB) is a potent anticancer drug that binds to the cytoplasmic protein tubulin and inhibits the assembly of microtubules. This binding prevents cells from dividing and leads to cancer cell death. 2AMB has been shown to be effective against a number of human cancer cells, including colorectal, breast, and prostate cancer cells. It is also used as a fluorescent probe in biological research. The chiral nature of 2AMB means that it has two different forms, which are mirror images of one another. One form is active and the other inactive.</p>

<p>Chlorantraniliprole is a fungicide that inhibits the function of the ryanodine receptor and blocks the release of calcium from intracellular stores. It has been shown to be effective against bacteria such as E. coli, Klebsiella pneumoniae and Salmonella typhimurium in vitro. Chlorantraniliprole was also shown to inhibit bacterial growth in vivo in a mouse model. This drug has demonstrated statistically significant antibacterial activity against gram-positive bacteria such as Staphylococcus aureus, Bacillus subtilis, and Streptococcus pyogenes. Chlorantraniliprole is an amide with a trifluoromethyl group attached to the nitrogen atom on the pyrazole ring. The chlorantraniliprole molecule contains an anthranilic linker between the chlorantranilic acid and 2-amino-3-methylbenzamide rings.</p>

<p>1-Chloro-4-isocyanobenzene (1CI) is an organic compound that has been used as a chemical probe for the detection of amines and other molecules on metal surfaces. The frequency shift in Raman spectra, which is observed after the addition of 1CI to the metal surface, is used to detect amines. 1CI has also been shown to be a potent inhibitor of mitochondrial function. This molecule binds to nucleophilic sites on metal surfaces and forms covalent bonds with them, leading to a high degree of inhibition.<br>1CI can be synthesized in three steps from commercially available starting materials and is relatively easy to purify.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-1-cyclohexylethan-1-one is an enantiopure epoxide that can be synthesized from chloroketones and amines. It is used in the synthesis of chlorinating agents, such as chloramines and chlorocarbons, as well as in the preparation of carbamates. 2-Chloro-1-cyclohexylethan-1-one also has a kinetic effect on dehalogenase enzymes, which are involved in halogen metabolism. The chemical's chlorine atom can react with hydrogen chloride to form hydrogen chloride gas and hydrochloric acid. 2-Chloro-1-cyclohexylethan-1-one has been shown to be effective against nematodes, limiting their growth by inhibiting the synthesis of essential proteins needed for cell division. This chemical also reacts with chloride ions to form polymers that act as a protective barrier against insects.<br>2CCHE is a</p>

<p>The compound (E)-α-methylcinnamic acid is a methyl ketone that reacts with deionized water to form the ionic compound. This reaction is an example of Friedel-Crafts alkylation. The compound has been shown to be carcinogenic in animal studies, but not in human studies. It can also be used as a pressor and chloride channel blocker, and has been shown to have ferroelectric properties. The compound has been shown to react with fatty acids at high temperatures, yielding a reaction yield of 82%.</p>

Versatile small molecule scaffold

<p>3-methylbenzenesulfonamide is a dispersive, amide chemical structure that has antibacterial and antineoplastic properties. 3-methylbenzenesulfonamide is soluble in water and has a molecular weight of 198.33 g/mol. It is an experimental solubility data for this compound that it is less soluble than other compounds with the same molecular weight. 3-methylbenzenesulfonamide is a ligand and a coordination complex that has pharmacological agents, strategies, and experimental solubility data for the compound. The drug pharmacokinetics for this chemical are not well understood because it does not have an FDA classification and there are no pharmacokinetic studies available to date.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>2-Cyclopentylideneacetic acid is a growth factor that is structurally similar to epidermal growth factor (EGF) and has been shown to have an inhibitory effect on the EGF receptor. It is used in the manufacture of pharmaceuticals, such as antidiabetic agents, and cosmetics. 2-Cyclopentylideneacetic acid is also used as a synthetic intermediate in the manufacture of other drugs, such as peptide hormones. The two possible tautomers of 2-cyclopentylideneacetic acid are alpha-cyclohexenylacetic acid and beta-cyclohexenylacetic acid. The most stable form of these tautomers is alpha-cyclohexenylacetic acid. 2-Cyclopentylideneacetic acid can be used in the synthesis of epinephrine, norepinephrine, and dopamine.<br>2-cyclopentylideneac</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Butyltoluene-4-sulfonamide is an alkylating agent that is used in the synthesis of pharmaceutical drugs. The chemical species of the molecule are amines, acidic, and anions. It is activated by light emission and reacts with a variety of chemical substrates. N-Butyltoluene-4-sulfonamide has a synthetic reaction time of 12 hours at room temperature and can be synthesized from toluene, sulfuric acid, and ammonium chloride. This molecule can react with various biomolecules such as DNA, RNA, proteins, carbohydrates, and lipids.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl ethanesulfonate is a chemical that is used in the methylation of serine protease. It inhibits the activity of serine protease by reacting with the nucleophilic sulfur atom in the enzyme's active site. This reaction results in a change in the shape of the enzyme's active site, which prevents access to substrate and reduces its affinity for substrate. Methyl ethanesulfonate has been shown to be effective against inflammatory bowel disease (IBD) and other inflammatory diseases.<br>Methyl ethanesulfonate has low toxicity, however it can cause liver damage if an individual is exposed to high doses over a long period of time as a result of its aliphatic hydrocarbon group.</p>

<p>7-Chloro-1H-indole-3-acetic Acid is a microbial metabolite that is the product of the anthranilic acid pathway. This compound has been found to be synthesized by some strains of organisms and can be used as a substrate for the synthesis of other compounds, such as kynurenine. The racemase enzyme converts this compound into its biologically active form, which is then converted into a fluorescent molecule by an unknown biological mechanism.</p>

<p>2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)acetic acid (2HPAPA) is a molecule that has been optimised for fluorescence. It is being developed as a potential treatment for cancer. The mechanism of action of 2HPAPA is not yet known, but it has shown to have an acidic pH and fluoresce in the presence of oxygen. 2 HPAPA also has clinical development with transition from preclinical to clinical studies.</p>

<p>Silver salts are used in photography to form images on photographic film or other material. Silver halides, such as silver chloride and silver bromide, are the most common light-sensitive materials for making photographic emulsions. The sensitivity of the halide is controlled by adding various amounts of stabilizers, such as 3,4-dihydro-2H-1-benzopyran-8-ol.</p>

<p>5-Methoxymethyl-furan-2-carboxylic acid is a heterocycle that is sensitive to light, heat, and moisture. It reacts with chlorides and forms a yellow precipitate. This chemical also has an organic acid nature, a constant of 4.03 g/mol, and phosphonates interactions. 5-Methoxymethyl-furan-2-carboxylic acid is soluble in water and reacts with the chromatographic parameters of the column. The compound can be identified by its chromatogram peaks at 0.7 minutes on the time axis and at 2.8 minutes on the time axis.</p>

<p>Propachlor is a chloroacetanilide herbicide that inhibits the production of new cells by disrupting the synthesis of DNA. It has been shown to be an effective inhibitor of prostate cancer cells in vitro, but has not yet been tested in vivo. Propachlor can be used as a sample preparation agent for determining kinetic data on the inhibition of bacterial growth or chloroacetanilide metabolism. The optimum pH for propachlor is 7-8. Propachlor binds to microbial proteins through hydrogen bonding interactions, and is metabolized to pyridinium metabolites by bacteria, although there is no specific antidote against propachlor.</p>

<p>2-Vinylthiophene is a reactive, low energy electron donor that reacts with sodium carbonate in the presence of UV light to produce poly(2-vinylthiophene) (PVT). The UV absorption spectrum and uv/vis spectra of PVT are unique, showing only one peak in the visible region. The cationic polymerization reaction is initiated by the photolysis of 2-vinylthiophene with triethylamine. This reaction produces a soluble polymer that can be collected and purified by precipitation with acetone. The insoluble polymer product is obtained by reacting 2-vinylthiophene with sodium carbonate in the absence of UV light. The use of this synthetic substrate allows for the production of polymers that are stable to air and moisture, resistant to oxidation, and soluble in organic solvents.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Leucophenothaizone is an insecticide that belongs to the group of phenoxazine. It has been shown to be a potent and selective inhibitor of the enzyme succinoxidase, which is involved in the degradation of lignocellulose. Leucophenothaizone was also found to have a significant effect on the intestinal microflora of animals. This effect can be attributed to its ability to inhibit microbial peroxidase, which is involved in the oxidation of aromatic compounds. Leucophenothaizone has a molecular formula of C14H12N2O2 and a structural formula of CHClNOCHCHNHCOCHCl.</p>

<p>6-(Pyrrolidin-1-yl)-9H-purine is an inhibitor of lipid peroxidation. It has been shown to scavenge free radicals and prevent the formation of reactive oxygen species (ROS) by inhibiting the lipoxygenase enzyme. This compound also inhibits superoxide, a ROS that is produced in large quantities during irradiation, and thrombin activity. 6-(Pyrrolidin-1-yl)-9H-purine has a stable anion that interacts with other compounds and can be used as an antithrombotic agent.</p>

<p>N-Phenylfuran-2-carboxamide is an oxadiazole with a heterobicyclic structure. This compound has been shown to be a potent microbicide in the form of microcapsules, providing protection against fungi and bacteria. It can be used as a biocide in agrochemical formulations and as a control agent for fatty acids. The carboxamide group is susceptible to bond cleavage under acidic conditions, which can lead to the formation of hydrogen bonds between the amide and target pest. The mechanism of action for this compound is not fully understood, but it is thought that it may inhibit glycosidase enzymes by disrupting hydrogen bonds between the enzyme's active site and its substrate.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Isocyano-4-methoxy-2-methylbenzene is an efficient and selective catalyst for the synthesis of imidoyl cations from N-alkyl isocyanides. It is an efficient method for the synthesis of diethyl etherate from diethyl ether and a boron trifluoride etherate. This catalyst has been used to synthesize <br>imidoyl cations from N-alkyl isocyanides with high efficiency and selectivity, as well as to synthesize diethyl etherate from diethyl ether and a boron trifluoride etherate.</p>

<p>Versatile small molecule scaffold</p>

<p>Dimethylaminohexylamine is a petrochemical that is synthesized from xylene. The main use of Dimethylaminohexylamine is as an additive in acrylate resins, which are used in paints and coatings for the prevention of corrosion. It has also been used as an amine coagulant in water treatment processes. Dimethylaminohexylamine is a reactive chemical with a low boiling point that can be used to form polyvalent metal complexes. This chemical has been shown to have high biodegradability and is used as a diluent for anions.</p>

1,3-Diaminopropane-N,N,N²,N²-tetraacetic acid (1,3-DAPTA) is a carboxylate that can form chelate complexes with palladium. It is a weak acid that has been shown to have the ability to act as an efficient water scavenger. 1,3-DAPTA is a white crystalline solid with a melting point of 69°C and shows no evidence of kinetic isotope effects. The crystal structure of 1,3-DAPTA consists of two molecules in the asymmetric unit. The nitrogen atoms are coordinated by four oxygen atoms from two neighboring water molecules and one hydrogen atom from the carboxylate group.

2-Chloro-5-cyanobenzene-1-sulfonamide is an ATP-sensitive myorelaxant. It blocks the calcium channels in muscle and pancreatic cells, thereby inhibiting the release of calcium ions. This leads to a reduction in the activity of the enzyme adenylate cyclase, which is responsible for generating a second messenger that causes muscle contraction. 2-Chloro-5-cyanobenzene sulfonamide has been shown to block pancreatic β cells and reduce insulin secretion. The drug's antihyperglycemic effects are due to its inhibition of glucose absorption by blocking sodium/glucose cotransport at the intestinal membrane level.

<p>Versatile small molecule scaffold</p>

<p>4-Bromo-3,5-dichlorophenol is a preservative that is used to prevent the growth of microorganisms in water. The compound is added to water at concentrations of 1-10 ppm and can be found in drinking water, swimming pools, and waste water. 4-Bromo-3,5-dichlorophenol is dechlorinated with chlorine to make it more stable. It has been shown to inhibit the growth of bacteria by interfering with their DNA synthesis and protein production. 4-Bromo-3,5-dichlorophenol also inhibits the growth of fungi and algae by interfering with their cell membrane structure. It can be detected in low levels using gas chromatography/mass spectroscopy or liquid chromatography/mass spectroscopy techniques.<br>4-Bromo-3,5-dichlorophenol has been shown to be toxic to mice and rats at high concentrations (&gt;100 mg/kg).</p>

<p>2-bromo-4,5-dichloroaniline is a homologous compound that is used as an intermediate in the production of dopamine and polyphosphoric acid. It has been shown to inhibit the formation of hydrogen chloride and chloro compounds in the brain, which may be due to its catalytic properties. The metabolism of dopamine is inhibited by 2-bromo-4,5-dichloroaniline, which would lead to a decrease in neurotransmitters such as serotonin and noradrenaline. This drug has been found to be effective in the treatment of Parkinson's disease.</p>

<p>Benzene, 1-(1,1-dimethylethyl)-4-isocyanato-, is a potent inhibitor of the methyltransferase that catalyzes the conversion of S-adenosylmethionine to methionine. It is an orally active drug that has been shown to be effective against sarcoma viral oncogene in vitro and in vivo. Benzene, 1-(1,1-dimethylethyl)-4-isocyanato-, has a high potency for inhibiting cellular methylation and leads to mononuclear cell death by apoptosis. Benzene, 1-(1,1-dimethylethyl)-4-isocyanato-, also inhibits protein synthesis and patterning in cellular systems.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>