Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5,6-Dimethoxynicotinic acid is a chemical compound that has been shown to inhibit tumor cell growth by inhibiting the synthesis of DNA and RNA. 5,6-Dimethoxynicotinic acid also inhibits the activity of promyelocytic leukemia (PML) protein in human lung cells. This drug has shown anti-tumor efficacy in xenograft mouse models, where it was able to inhibit tumor growth and prolong survival in mice with acute promyelocytic leukemia. 5,6-Dimethoxynicotinic acid is also being investigated as a potential chemotherapeutic agent in clinical trials.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Iodopropanedial is a pyridine compound. It is used as an antineoplastic agent in the treatment of cancer and damages cellular DNA by binding to nucleic acids and inhibiting protein synthesis. 2-Iodopropanedial also has acrylonitrile, a spectrum that includes antitumor activity and herbicides. 2-Iodopropanedial is an aromatic compound with carboxylic and ethynyl groups. The c-c bond provides its anti-tumor properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Ethyl-5-methylphenol is a natural product that belongs to the class of phenols. It is biosynthesized by the conversion of 2-methylacetophenone, which is found in styrene and exocrine glands in arachnids. This compound has been shown to be toxic to a number of bacteria, including strains resistant to antibiotics such as methicillin and cephalothin. The toxicity of 2-ethyl-5-methylphenol against bacteria may be due to its ability to inhibit protein synthesis and disrupt cellular membranes. The pathways leading from 2-methylacetophenone to 2-ethyl-5-methylphenol involve two steps: nitration followed by ethylation.<br>2E5MP can be synthesized using acetone and 3- methyl1 -butanol as precursors, which are scalable and inexpensive chemicals.</p>

<p>Versatile small molecule scaffold</p>

<p>Naphthalene-2-sulfonamide is a radical scavenger that has been shown to have antioxidant activity in the presence of peroxyl radicals. In vitro experimentation has shown that naphthalene-2-sulfonamide is capable of inhibiting butyrylcholinesterase, an enzyme responsible for breaking down acetylcholine, thereby increasing the levels of this neurotransmitter. This drug may be useful as a treatment for Alzheimer's disease, as it reduces the rate of plaque formation in the brain and slows down the progression of dementia. The optimum temperature range for sedimentation is between 20 and 30 degrees Celsius.</p>

<p>4-Pyridinecarboxylic Acid Ethyl Ester is a compound that belongs to the group of pyridinecarboxylic acids. It is a metabolite of nicotinamide, which is converted to 4-pyridinecarboxylic acid ethyl ester by esterases in the intestine. Nicotinamide is an important component of the vitamin B3 and has been shown to be effective for treating autoimmune diseases such as rheumatoid arthritis. 4-Pyridinecarboxylic Acid Ethyl Ester may have similar effects on inflammatory bowel disease and alopecia areata. The reaction mechanism of this compound has not been elucidated, but it has been shown to inhibit amyloid protein production in rat intestines. Hydroxyl groups on the side chain likely play a role in hydrogen bonding interactions with receptors in inflammatory bowel disease and alopecia areata.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Covid-19 is a drug that has been developed to help prevent and treat pandemics. Covid-19 is a resonance compound, which can be accessed by magnetic resonance. Covid-19 has two chemical shifts, which are related to the coupling constants between the nuclear spins in the molecule. The covid-19 molecule is made up of five different heterocycles and it has a constant magnetic resonance signal at 1H NMR. Covid-19 may be used for prevention and treatment of pandemic influenza A (H5N1) virus infection.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4,6-Diaminopyridine-3-carbonitrile (CAS No. 20520-22-4) is a synthetic dyestuff with red color and low solubility in water. It has been used as a dye for polyester and other synthetic fibers. The dye is soluble in organic solvents such as ethoxycarbonylethyl acetate and benzene, but insoluble in water. In addition to the red color, 4,6-diaminopyridine-3-carbonitrile has good lightfastness properties. This chemical is also a precursor to diazotized compounds that can be used to produce hydrogenated hydrocarbons.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydroxy-N-(2-hydroxyethyl)benzamide (4OHEBA) is a natural product that belongs to the class of phenolic compounds. It is found in macroalgae and has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. 4OHEBA has also been shown to have chemical diversity and studies show that it can be used in preservative systems.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Methoxybenzofuran-2-carboxylic acid is a synthetic compound that can be used as an intermediate in organic synthesis. It is stable and resistant to aqueous conditions, making it suitable for use in organic synthesis. 6-Methoxybenzofuran-2-carboxylic acid is also analogous to benzofurancarboxylic acids, which are characterized by their dianionic character. It has been shown to react with aldehydes at low temperatures and form tetrahydrofuran derivatives. 6-Methoxybenzofuran-2-carboxylic acid can be metallated with various metals to form stable complexes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Oxo-indoline-7-carboxylic acid is an antiinflammatory agent that belongs to the class of hydrazines. It has been shown to have antiinflammatory activity in stepwise manner, which starts with a hydrazine group attacking the carbonyl group of a carboxylic acid and forming a new heterocyclic ring. 2-Oxo-indoline-7-carboxylic acid also has esterase inhibitory effect and can be used for the treatment of inflammatory diseases such as rheumatoid arthritis.</p>

<p>5-Chloro-2-phenyl-1,3-benzothiazole is a benzothiazole with a phenyl ring and a phenyl group. It has two dihedral angles: one at the center of the ring system, and the other at the junction of the phenyl and benzene rings. The molecule has a molecular weight of 229.5 g/mol and a melting point of 243°C. 5-Chloro-2-phenyl-1,3-benzothiazole is used as an intermediate in chemical synthesis.</p>

<p>2-Methyl-4,6-bis(trichloromethyl)-1,3,5-triazine is a triazine with an ionic structure. It is used as a precursor to benzene and acetonitrile. The yields of 2-methyl-4,6-bis(trichloromethyl)-1,3,5-triazine are higher in the presence of benzene compared to acetonitrile. The quantum yield for 2-methyl-4,6-bis(trichloromethyl)-1,3,5-triazine has been found to be 0.2 from the photophysical properties of its emission spectrum. This technique has been used to detect small amounts of singlet oxygen that are generated by photolysis or irradiation with lasers.</p>

<p>Methyl 1-hydroxy-2-naphthoate is a wittig reaction product of hexane and chlorides. It is an alkyl ester that can be isolated as a colorless liquid with a boiling point of 87°C. The molecule has two tautomers, one of which is the 1-hydroxy-2-acetonaphthone and the other is the 1,2,3,4-tetrahydronapthalene. The hydroxynaphthoate group can undergo photostability to form the 1-hydroxy-2-acetonaphthone tautomer.</p>

<p>4-Amino-2,3,5,6-tetrafluorophenol is a hydrolyzing agent that is used in the production of nitrides. It hydrolyzes to form an amino group and a tetrafluorohydroxyl group. The industrial applications of 4-amino-2,3,5,6-tetrafluorophenol include its use as a target compound for the determination of the rate constant for hydrolysis. In addition to this application, it is also used as a reagent in organic synthesis.</p>

<p>2,3-Dihydro-1lambda6,2-benzothiazole-1,1-dione is a plant growth regulator that is used in horticultural applications. It is an anion that can be used as an additive to prevent corrosion and rusting of metals. 2,3-Dihydro-1lambda6,2-benzothiazole-1,1-dione reacts with chloride ions to form the corresponding chromatographic product. This compound also forms reaction products with other compounds such as pyrrole, amide and carbonyl group.</p>

<p>1-Chloro-4-(methylsulfinyl)benzene (MSMB) is a sulfoxide that is used as a regulatory agent. The toxicity of MSMB has been studied in several species, including the rat, mouse, and rabbit. Growth factor levels have been shown to be reduced with dietary concentrations of up to 100 ppm in rats. Depression was observed in both sexes at doses as low as 10 ppm. MSMB is metabolized by the liver and excreted primarily in the urine. It exhibits pharmacokinetic properties that are similar to those of other sulfoxides, including rapid absorption, high bioavailability, and rapid elimination.</p>

<p>5-Bromo-1-methyl-4-nitro-1H-imidazole is a nitroimidazole compound that has been shown to have antibacterial activity against gram-positive and gram-negative bacteria. The mechanism of action of this drug is not fully understood, but it is thought to be due to the ability of the drug to act as a substrate for bacterial nitroreductase enzymes, which are involved in nitrogen metabolism. 5BrNMI also inhibits DNA gyrase and topoisomerase IV and may inhibit cell wall synthesis. 5BrNMI can be used as an alternative treatment for infections caused by staphylococci or epidermidis.</p>

<p>3-Iodothiophene-2-carbaldehyde is a stable, n-oxide. 3-Iodothiophene-2-carbaldehyde has been shown to undergo thermolysis.</p>

<p>Isopentyl chloroformate is an organic solvent which belongs to the group of chloroformates. It has a structure similar to that of spirodiclofen, a compound with antagonistic properties that can be used for the treatment of blood pressure and disorders in the central nervous system. The chloroformate functional group has been shown to have anti-inflammatory effects on tumor tissue. Isopentyl chloroformate can be used as a pharmaceutical preparation for the treatment of neurological diseases, such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis.</p>

<p>m-Tolylacetic Acid is a synthetic compound that is used as an intermediate for the synthesis of epoxides. It is also found in natural compounds, such as filamentous fungus. m-Tolylacetic Acid has been shown to inhibit the growth of Candida albicans and other fungi by inhibiting the production of unsaturated ketones and active enzymes. The uptake and reaction products of this molecule have also been studied using molecular modeling techniques. The kinetic behaviour of m-tolylacetic acid chloride has been investigated using immobilized metal ion complexes and proton NMR spectroscopy.</p>

<p>3,4-Dibromophenol is a chemical compound that has been shown to have adverse health effects on humans. The emissions of 3,4-Dibromophenol are minimized by applying mathematical models that take into account the kinetic and thermodynamic parameters of the bromines and the energies in which they exist. Kinetic theory is used to explain the mechanisms of dimerization and isomers. Variational theory can be used to estimate activation energies for reactions. Functional theory can be applied to estimate theoretical values for parameters in kinetic equations.</p>

<p>N-Methylbenzamide is a hydrogen bond donor that participates in the transfer of a proton. It contains an amine group, which is highly reactive and can form hydrogen bonds with other molecules. The thermodynamic stability of N-methylbenzamide is due to the dihedral angle between the amine group and carbonyl group. This molecule has been shown to undergo asymmetric synthesis, which allows for the creation of enantiomers. N-Methylbenzamide has been used as a chiral auxiliary in chromatographic science to separate amino acids by using different solvents. N-Methylbenzamide has also been shown to react with sodium carbonate and water molecules, leading to the formation of an amide bond.</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2-Aminoethyl)-1H-indol-6-ol (3-OH-6) is a compound that is structurally related to the neurotransmitter acetylcholine. It has been shown to have an inhibitory effect on amines and blood pressure in cell culture. 3-OH-6 also has the ability to bind to model proteins such as tyrosinase. This binding inhibits the uptake of 3-OH-6, which leads to its accumulation in cells where it can cause damage by acting on adrenergic receptors. 3-(2 Aminoethyl)-1H-indol-6-ol’s ability to act on dopamine receptors may be due to its hydroxyl group.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dichlorobenzohydrazide (2,6-DCBH) is a non-polar compound that has hydrogen bonds. It is an isomer of 2,4-dichlorobenzol hydrazine and 3,5-dichloro-2-hydroxybenzohydrazide. It has a molecular weight of 146.07 g/mol and a melting point of 217°C. It is used as an intermediate in the production of herbicides such as 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-(2,4 dichlorophenoxy)propionic acid (MCPP).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>