Building Blocks

Applications Benzylmethyl-d3-amine HCl (CAS# 122025-10-9) is a useful isotopically labeled research compound.

Applications Methyl trans-Cinnamate-d5 (phenyl-d5) (CAS# 61764-82-7) is a useful isotopically labeled research compound.

Applications Intermediate in the preparation of hydroxylated Nebivolol metabolites.

Applications A useful synthetic intermediate.

Applications 2-Methyl-2-propane-d9-thiol (CAS# 99224-24-5) is a useful isotopically labeled research compound.

Applications 2-[[4-Ethyl-5-(2-furanyl)-4H-1,2,4-triazol-3-yl]thio]-1-(10H-phenothiazin-10-yl)-ethanone exhibits allosteric antagonism of insect odorant receptor ion channels.
References Jones, P.L., et al.: PLoS One, 7, 30304 (2012);

Applications 1-Bromododecane-d25 (CAS# 204259-66-5) is a useful isotopically labeled research compound.

Applications 4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC (CAS# 1523606-18-9) is a useful isotopically labeled research compound.

Applications Diethyl-d10-amine HCl (CAS# 285132-87-8) is a useful isotopically labeled research compound.

Applications 4-(Chloromethyl)benzoic Acid has been used in the synthesis of dihydroxy stilbene derivatives.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jung, M., et al.: Bioorg. Med. Chem. Lett., 16, 4481-4486 (2007);

Applications 3-Chloro-3-methyl-1-butyne is a propargyl chloride used to alkylate methanol, ethanol, ammonia and amines to the corresponding propargylic ether and amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hennion, G.F. et al.: J. Org. Chem., 34, 1319 (1969); Joshi, R. et al.: Tetrahedron, 49, 2353 (1993);

Applications Methyl 5-Chloro-2-methoxy-d3-benzoate (CAS# 1219803-33-4) is a useful isotopically labeled research compound.

Applications 3,5-dihydro-2H-1,5-benzothiazepin-4-one (cas# 53454-43-6) is a useful research chemical.

Applications Ethylene-13C2-diamine 2HCl (CAS# 77435-60-0) is a useful isotopically labeled research compound.

Applications 1,3-Difluoro-2-propanol is the major ingredient of Gliftor (G410000), a rodenticide. 1,3-Difluoro-2-propanol was also used in the synthesis of 1,3-difluoroacetone.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Menon, K., et al.: J. Biochem. Mol. Toxicol., 15, 47 (2001); Xie, W., et al.: J. Hygiene Res. 31, 316 (2002); Menon, K., et al.: J. Biochem. Mol. Toxicol., 15, 47 (2001)

Applications 1-Boc-hexahydro-1,4-diazepine is a diazepine derivative used in the preparation of pharmaceutical compounds such as histamine H3-receptor antagonists and dipeptidyl peptidase IV (DPP-IV) inhibitors.
References Curtis, M.P. et al.: Arch. Pharm., 337, 219 (2004); Ahn, J. et al.: Bioorg. Med. Chem. Lett., 18, 6525 (2008);

Applications 4-ethylpyrimidine-5-carboxylic acid (cas# 1147710-24-4) is a useful research chemical.

Applications 4-Bromochlorobenzene-d4 (CAS# 134415-42-2) is a useful isotopically labeled research compound.

Applications: 1,​2-​Bis(diphenylphosphin​o)​ethane is a chiral ligand used in organic synthesis in the hydroboration and cyclization of 1,6-enynes with pinacolborane.
References Yu, S. et al.: J. Am. Chem. Soc., 139, 6526 (2017);

Applications ethyl 2-cyclopropyl-2-hydroxyacetate (cas# 1185387-66-9) is a useful research chemical.

Applications 1-Bromo-3,4-difluorobenzene-d3 (CAS# 1219799-14-0) is a useful isotopically labeled research compound.

Applications Ethyl Glycolate has been shown to be a successful prodrug of glycolic acid to reduce skin irritation and to increase skin penetration.
References Yang, S.W., et. al.: Yakhak Hoechi, 40, 155 (1996)

Applications m-Tolylacetic acid is used as a reactant in the diastereoselective preparation of arylmethylene-isoindolinones.
References Anamimoghadam, Ommid, et al.: Beilstein J. of Org. Chem., 13, 2833-2841 (2017)

Applications Fmoc-Leu-OH-5,5,5-d3 is an isotope labelled compound of Fmoc-L-Leu-OH (F625015). Fmoc-L-Leu-OH is an amino acid derivative, used in peptide chemistry. It is also one of the novel PPARγ ligands that can activate PPARγ in different ways, that reduces osteoclasts differentiation, and thus are better therapeutic targets in diabetes than traditional antidiabetic drugs.
References Haochen, W., et al.: J. Cell. Biochem., 114, 1969 (2013)

Applications N,N-Dimethylaniline-2,3,4,5,6-d5 (CAS# 87385-38-4) is a useful isotopically labeled research compound.

Applications (±)-2-Ethylhexanoic-d15 Acid (CAS# 352431-38-0) is a useful isotopically labeled research compound.

Stability Very Very Moisture sensitive
Applications Chloroformic Acid Chloromethyl Ester is used as a reagent in the synthesis of carbamates and carbonates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Safadi, M. et al.: Pharm. Res. 10, 1350 (1993); Loren, J.C. et al.: Synlett, 18, 2847 (2005);

Applications L-Methionine-d3-N-FMOC (S-methyl-d3) (CAS# 502692-58-2) is a useful isotopically labeled research compound.

Applications S-Phenyl Benzenethiosulfonate is an high potency antifungal thiosulfonate that were tested against Aspergillus niger and Aspergillus flavus.
References Baeriocher, F.J., et al.: Aus. J. Chem., 53, 399 (2000);

Applications 1-Bromododecane-12,12,12-d3 (CAS# 204259-68-7) is a useful isotopically labeled research compound.

Applications Used as a reactant or reagent in preparation of N-alkyl carbamates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lazewska, D. et al.: BioMed. Chem. Let., 19, 6682 (2009);

Applications 1-Chloroanthraquinone is used to characterize anthraquinone intercalators as carrier molecules for second-generation platinum anticancer drugs.
References Gibson, D., et al.: J. Med. Chem., 34, 414 (1991); Gibson, D., et al.: Eur. J. Med. Chem., 32, 823 (1997); Alderden, R., et al.: Biochem. Pharmacol., 71, 1136 (2006)

Applications Ethyl 2-(1H-Pyrrol-2-yl)acetate is an intermediate in the synthesis of rac Ketorolac 6-Benzoyl Isomer (K235620). rac Ketorolac 6-Benzoyl Isomer (Ketorolac EP Impurity C) is an isomeric impurity of Ketorolac (K235620).

Applications Methyl 2-Formyl-3-hydroxybenzoate can be used to treat sickle cell disease.
References Metcalf, B.W., et.al.: PCT Int. Appl. WO 2020072377 A1, 146, (2020);

Applications Potassium Hexadecanoate-d31 (CAS# 63074-47-5) is a useful isotopically labeled research compound.

Applications 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
References Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)

Applications 1-Chloroadamantane-d15 is the isotope labelled analog of 1-Chloroadamantane, an adamantane derivative shown to exhibit virucidal activity against the Newcastle disease virus in chick embryo fibroblasts.
References Aigami, K., et al.: J. Med. Chem., 18, 713 (1975)

Applications 3'-Methoxyacetophenone-2',4',5',6'-d4 (CAS# 1219798-58-9) is a useful isotopically labeled research compound.

Applications Chlorotrianisene-d9 (trimethoxy-d9) (CAS# 1276197-26-2) is a useful isotopically labeled research compound.

Applications 5,6,7,8-tetrahydroquinazoline-6-carboxylic acid (cas# 1369096-46-7) is a useful research chemical.

Applications (±)-2-Chlorobutane-d9 (CAS# 175540-77-9) is a useful isotopically labeled research compound.

Applications Benzene-1,3-d2 (CAS# 14941-51-6) is a useful isotopically labeled research compound.

Applications O-Methylisourea Hemisulfate was used as a reagent in the preparation of (D,L)-arginine methyl ester analogs which display antiarrhythmic actiivity. It was also used in the synthesis of ethyl [6-methyl-2-methoxy-3-(substituted phenylethanone)-4-(substituted phenyl)]-1,2,3,4-tetrahydropyrimidine-5-carboxylates which display antimicrobial activity towards mycobacterium tuberculosis, staphylococcus aureus and bacillus subtilis at varying conentration ranges.
References Banfi, A., et al.: Synthetic. Commun., 19, 1787 (1989); Chikhale, R., et. al.: Pharma Chemica, 1, 247 (2009);

Applications 5-Methyl-1,3-cyclohexanedione has been used in the synthesis of racemic (±)-fawcettimine and 3,6-dimethyl-2-phenylsulfanyl-3,5,6,7-tetrahydro-2H-benzofuran-4-one.
References Xin, L., et al.: Angewandte Chemie (International Edition), 46, 7671 (2007); Lee, Y., et al.: Korean Chem. Soc., 23, 1477 (2002)

Applications 5-Methoxy-1-naphthalenol (cas# 3588-80-5) is a compound useful in organic synthesis.

Applications Methyliminodiacetic-d4 Acid (CAS# 1219803-27-6) is a useful isotopically labeled research compound.

Applications N-Fmoc-L-cysteine is the N-Fmoc-protected form of L-Cysteine (C995000), a non-essential α-amino acid that is biosynthesized in humans. L-Cysteine is also a bicarbonate-sensitive endogenous excitotoxin in rats and possibly humans.
References Li, Q. et al.: Mat. Lett., 64, 614 (2010); Olney, J., et al.: Science, 4, 596 (1990)

Applications 1-Chloropropane-d7 (CAS# 761374-88-3) is a useful isotopically labeled research compound.

Applications 1-Chloropropane-1,1-d2 (CAS# 125640-23-5) is a useful isotopically labeled research compound.

Applications 5-Bromo-2-fluorobenzonitrile

Applications N-Methyliminodiacetic Acid (cas# 4408-64-4) is a compound useful in organic synthesis.

Applications Choline-d9 Bromide (N,N,N-trimethyl-d9) (CAS# 285979-71-7) is a useful isotopically labeled research compound.

Applications 4-Methylimidazole-d6 (CAS# 1219804-79-1) is a useful isotopically labeled research compound.

Applications A metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.
References Paterson, J.R., et al.: Biochem. Biophys. Res. Comm., 116, 449 (1983), Taurog, A., et al.: Endocrinology, 124, 30 (1989).

Applications N,N'-Bis(2,6-diisopropylphenyl)-1,6,7,12-tetraphenoxy-3,4,9,10-perylenetetracarboxylic Diimide has applications in the photosensors and optical detectors.
References Wang, Shaojun, et al.: ACS Photonics, 5(6), 2478-2485 (2018);Wang, Hanlin, et al.: Adv. Mat., 29(32), n/a. (2017)

Applications Fmoc-L-cyclopropylalanine is used to develop low molecular weight HIV-1 protease dimerization inhibitors. It is also used to prepare piperazinone derivatives as a novel class of potent HCV NS4B inhibitors.
References Hwang, Y., et al.: J. Med. Chem., 48, 2239 (2005); Kakaria, R., et al.: J. Med. Chem., 57, 2136 (2014)

Applications 7-Methoxy-1-tetralone (cas# 6836-19-7) is a compound useful in organic synthesis.

Applications Tenovin 1 is a sirtuin inhibitor.
References McCarthy, A.R., et. al.: Bioorg. Med. Chem., 20, 1779 (2012)

Applications 2-Cyclopropylethyl-1,1,2,2-d4-amine (CAS# 1219795-00-2) is a useful isotopically labeled research compound.

Applications Fmoc-Cop is used in the synthesis of disubstituted pyrimidines as Lck inhibitors.
References Hunt, J., et al.: Bioorg. Med. Chem. Lett., 19, 5440 (2009)

Applications 3-Ethyl-d5-toluene is labelled 3-Ethyltoluene which is a useful synthetic intermediate.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 4-Cholesten-3-one-3,4-13C2 (CAS# 82938-09-8) is a useful isotopically labeled research compound.

Applications tert-Butyl-d9 Acrylate (CAS# 928163-00-2) is a useful isotopically labeled research compound.

Applications (E)-1-Phenyl-1-butene was used to study olefin oxidation by cytochrome P-450. It can be used to synthesize nonracemic allylic amines. It can also be used to prepare aryl oxiranes by direct epoxidation.
References Liebler, D., et al.: Biochem., 22, 5482 (1983); Liang, C., et al.: J. Am. Chem. Soc., 130, 343 (2008); Imuta, M., et al.: J. Org. Chem., 44, 1351 (1979)

Applications L-Phenylalanine-3,3-d2 (CAS# 221346-31-2) is a useful isotopically labeled research compound.

Applications 4-Methylcyclohexanemethanol is patented for use as an ingridient of air fresheners. It can also be used to synthesize thiazolidinedione (2,4-thiazolidinedione, T344250) derivatives as 15-PGDH inhibitors.
References Wu, Y., et al.: Bioorg. Med. Chem., 18, 1428 (2010);