Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methylcyclopropanecarboxamide is a compound that has been shown to have anticoagulant properties. It binds to the active site of coagulation factor Xa and inhibits its activity, thereby preventing blood clots from forming. 2-Methylcyclopropanecarboxamide has also been shown to be an immunosuppressant, demonstrating a decrease in antibody response and reduced intestinal inflammation in mice. This drug has potential use as an anti-inflammatory agent or for the treatment of autoimmune diseases.</p>

<p>N-(Methylcarbamoyl)acetamido N-methylcarbamate (NMCA) is a novel anti-cancer compound that selectively binds to the CB2 receptor. NMCA has been shown to inhibit the growth of cancer cells in vitro and in vivo, as well as reduce the size of bowel tumors. It also has a beneficial effect on cardiac function. The mechanism of action is not completely understood, but it may be due to binding to the CB2 receptor and blocking the activation of other receptors such as TNF-α. NMCA can be formulated into biocompatible polymers that are suitable for drug delivery. Furthermore, this compound can be used for treating inflammatory bowel disease and renal cell cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1H-Indazol-4-ol is a synthetic chemical with the molecular formula CHNO. It is the chloride, nitro, diammonium, enamine, divalent, methyl ester, acrylonitrile, polyethylene terephthalate and anion form of 1H-indazole. 1H-Indazol-4-ol is used in the synthesis of aminonaphthalenes and triazoles. The polymerization reaction for the production of cellulose acetate is also catalyzed by 1H-indazole. This chemical has been shown to have anion properties in solvents such as water and alcohols.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Imazapyr is a herbicide that inhibits the activity of acetolactate synthase, an enzyme essential for plant growth. Imazapyr binds to the active site of acetolactate synthase and forms a stable complex with the enzyme, thereby inhibiting its activity. Imazapyr has been shown to have a low toxicity in mammals and is not absorbed through skin or lungs. This herbicide is also toxic to plants and fish, as it inhibits their growth by disrupting photosynthesis. Imazapyr does not bind to DNA, thus it does not induce mutations in bacterial chromosomes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about Trimethyl(trifluoromethyl)silane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5,8-Dibromoquinoline is a synthetic trisubstituted quinoline derivative that has been shown to form frameworks with nitrogen atoms. It has been synthesized from 2-hydroxyphenylacetic acid, which upon dehydration gives the corresponding n-oxide. 5,8-Dibromoquinoline forms an acidic solution in water and an alkaline solution in ethanol. 5,8-Dibromoquinoline can be hydrolysed by both acidic and alkaline conditions to produce 2,4-dichlorobenzene and 2-bromophenol. The reaction is stereoselective with the formation of only one product.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2-Phenylethoxy)acetic acid is an oleylethanolamide that has been shown to have antibacterial activity. It has been shown to activate lysosomal hydrolases and inhibit the growth of bacterial cells. 2-(2-Phenylethoxy)acetic acid also inhibits the synthesis of inflammatory molecules, such as leukotrienes, prostaglandins, and cytokines. This drug is a potent inhibitor of phospholipase A2 and can be used for the treatment of inflammatory diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-Bromooct-1-yne has a chiral carbon and is therefore optically active. It has a boiling point of about 44 degrees Celsius, and it is soluble in ether and chloroform but not in water. The compound is stable at temperatures up to 130 degrees Celsius, and it is soluble in benzene and acetone but not in acetone. 8-Bromooct-1-yne has an optical rotation of +10.5 degrees. The molecule can be monosubstituted with a hydrogen atom or halogen atom, which changes the optical properties of the molecule. 8-Bromooct-1-yne has dichroism when viewed under polarized light, which means that the molecule absorbs light differently when it is rotated by 90° compared to when it is rotated by 0°. The compound's fluorescence emission maxima are at 488 nm and 514 nm. 8-Bromooct-1-yne's con</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(tert-Butyl)-2-chloropyridine is a ligand that has been used in the synthesis of a number of boronic acids and quinoline derivatives. It is also useful in cross-coupling reactions, which are nucleophilic substitution reactions involving two partners, such as an organometallic reagent and an organic halide or pseudohalide. The linker can be any group that connects the two partners together for these reactions. 4-(tert-Butyl)-2-chloropyridine is stable under acidic conditions, making it an excellent choice for coupling with amines to produce amides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methyl-1H-indazol-4-amine is a tyrosine kinase inhibitor that has been shown to be potent in inhibiting the activity of various types of tyrosine kinases. It has good oral pharmacokinetics and is not metabolized by the liver. 5-Methyl-1H-indazol-4-amine binds to the ATP site on the enzyme and prevents phosphorylation, which inhibits cell proliferation and growth. This agent also inhibits DNA synthesis, protein synthesis, and phosphoinositide turnover in cells. 5-Methyl-1H-indazol-4-amine is an orally active inhibitor of tyrosine kinases with good oral pharmacokinetics and does not require metabolic activation by the liver. This agent may be used for the treatment of cancer or other diseases associated with uncontrolled cell growth.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chlorocyclohex-1-ene-1-carboxylic acid is a synthetic compound that has been used as a reactant for the production of phthalic anhydride. The reaction mechanism begins with the formation of isocyanide, which reacts with benzoic acid to form an intermediate benzoyl isocyanide. This intermediate reacts with the acetic acid to produce 2-chlorocyclohexanecarboxylic acid, which in turn undergoes hydrolysis to give phthalic anhydride.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-Chloroimidazo[1,5-a]pyrazine is a potent insulin-like growth factor-I receptor (IGF-IR) inhibitor with potential therapeutic use for type II diabetes. It was found to inhibit IGF-I induced activation of the IR and downstream signaling pathways in a dose dependent manner. 8-Chloroimidazo[1,5-a]pyrazine inhibited IGF-I induced mitogenesis in human colon cancer cells and showed antiangiogenic activity in nude mice bearing xenografts of human colon cancer cells.</p>

<p>7H,8H-Imidazo[1,5-a]pyrazin-8-one is a potent and selective inhibitor of the bromodomain family. Bromodomains are protein domains found in many proteins that have been implicated in regulating gene expression, DNA repair, and protein degradation. Inhibiting this domain leads to decreased proliferation of tumor cells. 7H,8H-Imidazo[1,5-a]pyrazin-8-one has also shown potential as an anti-neurodegenerative agent by inhibiting the enzyme acetylcholinesterase. This compound is active against cancerous cell lines and is crystalline with a polymorphic form that can be used for medicine production.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(E)-3-Cyclohexylacrylic acid is an antibacterial agent that inhibits the growth of bacteria by binding to the 50S ribosomal subunit. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. (E)-3-Cyclohexylacrylic acid has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This compound also has anticancer activity, which may be due to its ability to inhibit topoisomerase II activity in cells.</p>

<p>Cyclopentane-1,2-dicarboxylic acid is an organic compound with the molecular formula C5H8O4. The molecule consists of a cyclopentane ring and two carboxylic acid groups. Cyclopentane-1,2-dicarboxylic acid can be synthesized by an intramolecular cyclization reaction between a 1-bromocyclopentane and a chalcone. This reagent can also be used to synthesize other compounds such as phenoxyethanol, an enolate, and organozinc compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 2-cyanocyclopropane-1-carboxylate is a reactive chemical reagent that can be used to synthesize a variety of compounds. It is an aliphatic compound with a carbonyl group at the end of the molecule and belongs to a class of compounds called chlorohydrins. Ethyl 2-cyanocyclopropane-1-carboxylate has been used as an organoindium compound for the synthesis of stilbene derivatives. It can also be used to synthesize chlorinated alkenes, oxiranes, and other cyclopropanes. Ethyl 2-cyanocyclopropane-1-carboxylate can react with alcohols or phenols in presence of acid to form acetals or ketals, respectively.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2S)-2-Propanamidopropanoic acid is a non-protein amino acid that is used in the synthesis of peptides. It has an acidic side chain and can be reacted with amines to form a beta-amide linkage. These reactions are catalyzed by enzymes such as proteases and thiols. This compound has been shown to inhibit the activity of proteases, which may be due to its ability to compete for binding sites on the enzyme. The equilibrium constant for this reaction is 1.5 x 10^9 M^(-1).</p>

<p>1-(Acetyloxy)heptyl acetate is an organic compound that has the molecular formula CH3COOC7H15. It is a colorless liquid with boiling point of 174°C at 1 mmHg. This compound is used as a solvent, and it is also used in the synthesis of some pharmaceuticals. The melting point of 1-(acetyloxy)heptyl acetate varies depending on the temperature because this compound exists as two polymorphs. The compound can be activated by heating to temperatures above 145°C, which will cause it to form hydrogen bonds with water molecules. One of the major uses for 1-(acetyloxy)heptyl acetate is as an excipient in tablets and capsules. The most common use for this substance is in pharmaceuticals that are taken orally and require solvents or solubilizers to dissolve other components such as inactive ingredients, active ingredients, or colors.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>o-[3-(Dimethylamino)propyl]hydroxylamine dihydrochloride is a drug used to treat cardiovascular disorders. It is a prodrug that is metabolized in the body to form hydroxylamine, which has affinity for c1-6 alkyl groups. The hydroxyl group on the heterocycle of o-[3-(Dimethylamino)propyl]hydroxylamine dihydrochloride also has biological properties. This drug is an inhibitor of monoamine oxidase and may reduce the risk of heart disease by lowering blood pressure and decreasing cholesterol levels. The stereoisomers of this compound are used for the treatment of hypertension. The benzyl group on o-[3-(Dimethylamino)propyl]hydroxylamine dihydrochloride may be responsible for its ability to inhibit monoamine oxidase A and B, as well as other enzymes involved in cardiovascular diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Benzylsulfamoyl chloride is an inhibitor of the enzyme, racemase. This inhibitor has been shown to be active against a variety of hyperproliferative diseases. N-Benzylsulfamoyl chloride inhibits the production of cell proteins and can be used for the treatment of mycoses and thioether-related disorders. It also has cytoprotective activity in liver cells and neuronal cells, which may be due to its ability to inhibit carboxyalkylases.</p>