Building Blocks

<p>3-Bromobenzothiophene-2-carboxylic acid is an organic compound that is used in the synthesis of pharmaceuticals, including anticancer agents. It inhibits the growth of cancer cells by binding to a specific site on their DNA and preventing the formation of terminal alkynes. 3-Bromobenzothiophene-2-carboxylic acid has been shown to be a potent inhibitor of lactamase, which is an enzyme that breaks down lactams and other esters. This effect leads to decreased cell proliferation in some cancer cells. 3-Bromobenzothiophene-2-carboxylic acid also has a fluorescent property, which can be used for research purposes.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Formylfuran-2-carboxylic acid is a furanic sugar derivative that is used as a sweetener. It can be obtained by the reaction of glycerol with formaldehyde and catalytic acid. 3-Formylfuran-2-carboxylic acid has a particle size of less than 2 microns, which means it can be used in chewing gum and other food products. This product has been shown to have antioxidant activity due to its ability to scavenge free radicals and inhibit oxidation, making it suitable for use as a preservative.</p>

<p>Ethyl 1,3-benzothiazol-2-ylacetate is a coumarin derivative that has been shown to be active against tuberculosis. It inhibits bacterial growth by binding to the gyrase enzyme and preventing the formation of a new DNA strand. The synthesis of ethyl 1,3-benzothiazol-2-ylacetate starts with the condensation of 2 molecules of acetoacetic ester in the presence of an acid catalyst. This reaction takes place in vivo in animal tissues and is catalyzed by enzymes such as gyrase or topoisomerase IV. The reaction time for this synthesis is typically 3 hours. Ethyl 1,3-benzothiazol-2-ylacetate emits fluorescent emissions at a wavelength of 330 nanometers.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methoxy-2-thiophenecarboxylic acid is an aldehyde that is synthesized by the reaction of lithium, phosphoryl chloride and thiophene. The azomethine group in this compound can be converted to the corresponding phosphoryl chloride and sulfides. 5-Methoxy-2-thiophenecarboxylic acid is used as an intermediate for manufacturing dyes and pharmaceuticals, such as analgesics and antibiotics.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2S)-2-{[(2S)-5-Oxopyrrolidin-2-yl]formamido}pentanedioic acid is an optically active glutamic acid amide, which is a natural product. It has a bitter taste and may be found in soybeans and zinc salts. The salt form of this compound is used as a mouthwash to reduce the sensation of bitterness. This compound has been reported to have anti-inflammatory activities and has been shown to inhibit the growth of Aspergillus flavus and other fungi.</p>

<p>Versatile small molecule scaffold</p>

<p>Fa-Gly-OH is a molecule that is used to study the kinetics of drug metabolism and the metabolism of drugs. It can be synthesized from glycerol and furfural, which are both readily available chemicals. Fa-Gly-OH has been shown to have a magnetic resonance profile that is similar to that of other fatty acids. The metabolic profile of this molecule was determined in groups of mice, with doses ranging from 10 mg/kg to 500 mg/kg. Fa-Gly-OH was found to be metabolized in the liver, with no detectable levels in the urine or faeces. Fa-Gly-OH is eventually converted into conjugates, such as methylglyoxal, which are excreted in the urine and faeces.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1,2-Benzothiazol-3-yl)acetic acid is a plant hormone that is found in the indole-3-acetic acid family of plant hormones. It is one of the auxins and it has been shown to promote germination and root growth. Auxins have also been shown to be involved in the development of vascular tissue and other aspects of plant growth. 2-(1,2-Benzothiazol-3-yl)acetic acid has been isolated from Pisum sativum L., Lycopersicon esculentum, and Esculentum.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 2-methyl-3-oxohexanoate is an ester with a chemical formula of C8H14O2. It is an acyclic compound and a member of the ethers family. It has the molecular weight of 132.17 g/mol and a density of 0.965 g/mL at 25°C. The melting point for this compound is -78°C and it has a boiling point of 164°F (73°C). Ethyl 2-methyl-3-oxohexanoate has been found to have high levels in Delphinium species, which are plants that contain alkaloids such as methyllycaconitine, which are analogues to the more well known morphine. This ester can be synthesized from the reaction between ethyl acetate and benzaldehyde.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine is a functional molecule that belongs to the pyridazinone class. It has been shown to be an ionic liquid with a dihedral angle of tetragonally and a water molecule as a hydrogen bond donor. 3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine has been used in diagnostic techniques such as potentiodynamic polarization and electrochemical impedance spectroscopy.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Ethyl-3-(2-hydroxyethyl)urea is a chemical compound that is an equimolar mixture of two isomers, 1-ethyl-3-(2-hydroxyethyl)urea and 3-(2-hydroxyethyl)-1-methylurea. It has been shown to induce death in tumor cells, but not in normal cells. The molecular targets for this compound are the mitochondria and the DNA, which are essential for cell growth and division. This drug also has carcinogenic properties, meaning that it can cause cancer. In animal studies, 1-ethyl-3-(2-hydroxyethyl)urea has been shown to cause thyroid tumors and astrocytomas (brain tumors). In addition, this drug causes hepatocellular carcinoma in rats and gliomas (brain tumors) in animals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(2R)-1-Phenylbutan-2-ol is an isomer of 1-phenyl-2-propanol. It has been shown to have potent antituberculosis activity, with a high yield and good stereochemical purity. In the tautomeric form, it inhibits the growth of Mycobacterium tuberculosis by inhibiting protein synthesis.</p>

<p>5-acetyltetrahydrofuran-2-one (5AHT) is a natural compound that has been shown to have antimicrobial and antioxidant properties. It is a biomimetic of glutamic acid, which has been shown to have biological properties such as anti-inflammatory, antipyretic, analgesic and antidiabetic effects. 5AHT has been used in the preparation of diethyl succinate, an organic acid that has potential applications in food chemistry. The chemical structure of 5AHT consists of two carbonyl groups bonded to a furan ring with two hydroxyl groups on the other side. The resonance mass spectrum of 5AHT consists of an acetaldehyde peak at 20 ppm and a peak at 77 ppm for the methylene protons. The 5AHT molecule can exist in two isomers: <br>5AHT (E)-OCH3 or 5AHT (Z)-OCH3</p>

<p>N,N-Dimethyl-2-(N-methylacetamido)acetamide is an amide compound that is used as a solvent. It has a molecular weight of 143.16 and boiling point of 209 °C. This compound has been experimentally shown to have n-terminal kinetic stabilization and orbital interaction with the acceptor molecule. N,N-Dimethyl-2-(N-methylacetamido)acetamide is also underivatized, meaning it does not contain any functional groups for further chemical reactions. The conformational stability of this compound is dependent on the carbonyl oxygen at the c-terminus in addition to its electron affinities.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromobenzohydrazide is an antibacterial agent that has been shown to have good intestinal absorption. It is a crystalline solid, which is soluble in organic solvents and insoluble in water. The molecular weight of 2-bromobenzohydrazide is 238.24 g/mol, with a melting point of 108°C. 2-Bromobenzohydrazide has been shown to be active against Streptococcus aureus, Mycobacterium tuberculosis, and other bacterial strains. The mechanism of action for 2-bromobenzohydrazide involves the formation of a covalent bond with amino groups on the cell wall or membrane surface of bacteria, which results in damage to the bacterial cell membrane. This inhibits the synthesis of proteins and nucleic acids as well as causes death by inhibiting cellular respiration.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methylthiophene-3-carbaldehyde is a ketone that is the product of the reaction between 3,4-dimethoxybenzaldehyde and acetic acid. It is a colorless liquid with a sweet odor. 5-Methylthiophene-3-carbaldehyde has been used as a reagent for the synthesis of benzylic alcohols and as a starting material for other organic compounds.</p>

<p>4-Bromo-5-methylthiophene-2-carboxaldehyde (BMTCA) is a chemical that is synthesised by the reaction of ethylene with irradiation. It has been shown to have photochromic properties and can be used as an alternative to 4,4'-dithiodimorpholine (DIMO). BMTCA is hydrophilic and can be used for the synthesis of homologues. It also undergoes an x-ray structure analysis, yielding information on its physical properties and how it reacts with other chemicals. The process of digitalization allows for the conversion of analog signals into digital signals. This process uses a shift register, which is a device that stores data in sequential memory cells and outputs them on a single line. The diels–alder reaction is a chemical reaction between two unsaturated compounds to form 1,3-dienes or 1,4-diynes. This reaction is highly useful because it can</p>

<p>6-Hydroxy-4,4-dimethyl-3,4-dihydro-2H-1-benzopyran-2-one (6HDM) is a lipid lowering agent that has been shown to have antibacterial activity. It is a synthetic drug with an optical imaging technique that has been shown to inhibit the growth of cancer cells in vitro. 6HDM also inhibits UVB induced skin cancer by decreasing the expression of p65. 6HDM inhibits the biosynthesis of nucleic acids and protein synthesis in cancer cells by acting as a competitive inhibitor for intramolecular hydrogen transfer. This leads to cell death through apoptosis and necrosis.</p>

<p>7-Oxoheptyl acetate is a synthetic pheromone that has been shown to be an attractant for Lepidoptera. It is one of many compounds in the synthetic mixture 7-oxo-6,7,8,9-tetrahydro-1,4-benzodioxepin and it is used as an alternative to the natural pheromone (Z)-7-dodecenol. This compound has been shown to be stereoselective with respect to its ability to attract male moths. The compound was synthesized by Wittig reaction between the nitro group and hydroxyl group of 7-oxoheptanol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide is a cyclic compound that has been the subject of extensive study and research. Its synthesis was first reported in 1887, but it was not until 1985 that its chemical structure was elucidated. It has been shown to be an effective inhibitor of acetylcholinesterase. Dihydro-2H-thiopyran-3(4H)-one-1,1-dioxide is used as a reagent in screening for active methylene compounds. It can be used to synthesize aldehydes and azides. This molecule has also been studied extensively by x-ray crystallography and other techniques.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenylpyrazine is an organic compound that belongs to the group of phenylpyrazines. It has been shown to bind to the 5-HT7 receptor, and can be used as a ligand for studying the function of these receptors. 2-Phenylpyrazine has also been shown to bind to adenosine receptors, and may modulate their activity. It has been found in various types of organisms, including plants, fungi, bacteria, and animals. 2-Phenylpyrazine can be synthesized by reacting pyrazine-2-carboxylic acid with a hydroxyl group or an organometallic reagent such as LiAlH4 or ZnCl2. It is soluble in water and methanol but insoluble in ethers. The crystal structure of 2-phenylpyrazine is a ferroelectric liquid crystal composed of a skeleton with alternating single and double bonds.</p>

<p>Versatile small molecule scaffold</p>

<p>Cyclohexanol is a cancer activator that can be injected or implanted. It is a monovalent, water-soluble, lipophilic molecule with a molecular weight of 194.1 g/mol and a log P of 1.8. Cyclohexanol has been shown to induce the death of cancer cells by activating the apoptotic pathway in vitro. This compound also increases the sensitivity of cancer cells to ionizing radiation and induces tumor cell death in vivo. Cyclohexanol may be used as a diagnostic tool for identifying tumours based on its ability to bind to targetable receptors expressed at high levels in cancer cells, such as those involved in cellular proliferation and angiogenesis.</p>

<p>2-(Cyclopropyl)thiophene is a non-steroidal anti-inflammatory drug (NSAID) that is used for the treatment of bowel disease. 2-(Cyclopropyl)thiophene inhibits the production of prostaglandins, which are involved in many physiological processes, including the inflammatory response. 2-(Cyclopropyl)thiophene is metabolized to its active form, 2-hydroxythiophene, by dehydrogenase enzymes and has been shown to have anti-inflammatory properties. It also has been shown to have cardiovascular effects and can be used to treat heart disease. The structural formula for this compound is C1-6 alkyl--CH2--CH2--S--CH3.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-5-(cyclopropyl)thiophene is an anhydride that is part of a class of compounds called thiophenes. These compounds are used to attack nitryl groups, which are cations with a nitrogen atom in the +3 oxidation state. Nitration of 2-bromo-5-(cyclopropyl)thiophene produces 2-bromo-5-(cyclopropyl)thioaniline, which is used as a reagent for the synthesis of dyes and pharmaceuticals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 7-methyloctanoate is a silicone that can be used as a nutrient or as an emulsifier in skin care products. It has high water retention capacity, and can be used to form lipid bilayers in liposomes. Ethyl 7-methyloctanoate has been shown to have antioxidant properties, which is due to its ability to scavenge free radicals and inhibit lipid peroxidation. This compound also has the ability to protect against UV radiation induced damage by absorbing UV light and converting it into heat.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-2,6-diphenylpyrimidine is a chemical compound that exhibits growth-regulating properties. It has been used as a solvent for the synthesis of other organic compounds. 4-Chloro-2,6-diphenylpyrimidine is a tautomeric compound with two different forms: the catechol and the ketone form. The catechol form is more stable than the ketone form and can be activated by light or heat to produce an excited state. This excited state can emit light in the visible region of the spectrum, which can be measured using fluorescence spectroscopy. 4-Chloro-2,6-diphenylpyrimidine also has high solubility in water and good transport properties. This chemical has been shown to have thermally activated rearrangements and amide cleavage reactions when heated or subjected to acid conditions.</p>

<p>Versatile small molecule scaffold</p>

<p>Azepane-2,4-dione is a reactive intermediate in the synthesis of quinolines. It can be synthesized by acid treatment of benzofuran, followed by condensation with piperidine and quinone, or by condensation of 2-aminoethanethiol with chloroacetyl chloride. Azepane-2,4-dione is not stable and spontaneously reacts with water to form an adduct. The compound can be converted to the corresponding quinoline through a two step process involving enamine formation and cyclization. This reaction is catalyzed by palladium on carbon or stannic chloride on alumina.</p>

<p>Versatile small molecule scaffold</p>

<p>1-Phenylcyclopropan-1-ol is a reactive oxygen species (ROS) that can be used as an endogenous substrate for the cytochrome P450 enzymes. 1-Phenylcyclopropan-1-ol has been shown to activate NADPH cytochrome P450 reductase in human liver microsomes and rat liver microsomes. It is also known to inhibit the formation of azides from drugs such as diphosphine and polyclonal antibodies, and has been proposed to be an immunosuppressant drug. 1-Phenylcyclopropan-1-ol has been shown to inhibit the growth of cancer cells in vivo, which may be due to its ability to induce apoptosis.<br>!--<br>--&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1H-Imidazol-2-yl)aniline is an antimycobacterial agent that can be used concurrently with diethylamine. It has been shown to react with acetone and phenyl isocyanate to form a series of compounds, including 2-(1H-imidazol-2-yl)acetophenone, 2-(1H-imidazol-2-yl)-N,N'-dimethylformamide, and 2-(1H-imidazol-2-yl)-N,N'-diisopropylethane diamide. The substituents on the imidazole ring are reactive and can form aliphatic carbamates or isocyanates.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2-methyl-3-oxo-3-phenylpropanoate is a zerovalent metallorganic compound. It is used as an intermediate in the synthesis of other compounds and has been found to be a good catalyst for the benzoylation of olefins. The compound is prepared by reacting an azide with a benzyl alcohol. This reaction proceeds via an initial hydrolysis of the azide to form a chloride, followed by substitution of the chloride with the alcohol to form the desired product. The catalytic mechanism is thought to involve magnesium ions, which are reduced to magnesium cations upon addition of chloride ions.<br>The compound has not been shown to produce any toxic effects in humans and can be safely handled without protective equipment.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Ethylsulfanyl)phenol is a hyphenated chemical compound that has been shown to be toxic to cells. It is a radical that can form in the body, and it has been found to have high potential for health risks. The reaction time for 2-(Ethylsulfanyl)phenol is an average of 130 seconds, which is much faster than most other chemicals. Kinetics for this compound are also rapid, with an average rate of 10-14 μmol/L per second. 2-(Ethylsulfanyl)phenol reacts with DNA at the scission site, which generates a free radical that damages the DNA strand and breaks it down into smaller fragments. This chemical has been shown to cause DNA damage at a rate of 0.1% per hour, which can lead to cell death and cancer development.</p>

<p>3-Methylpiperidine-2,6-dione is a dipeptide that is used to form an oral drug delivery system. It is encapsulated in silicone and has affinity for hydrogen peroxide. A heterostructure is created by sandwiching the 3-methylpiperidine-2,6-dione between two layers of acrylate. This creates a device that can be activated by light and will release the dipeptide when it reaches a specific pH level. The acrylates are dissolved in an oxocarboxylic acid, which also denatures the peptide to prevent proteolysis by enzymes in the stomach. Once it reaches the small intestine, the phthalimides are cleaved from the 3-methylpiperidine-2,6-dione, leaving behind an intact dipeptide.</p>

<p>Versatile small molecule scaffold</p>

<p>Cyclopropylthiophene is a compound that can be synthesized by arylation of 3-cyclopropyl-thiophene with an aryl iodide in the presence of copper. The reaction can be catalyzed by diaryliodonium salts, and the selectivities are determined by the counterion. Cyclopropylthiophene is used as a model substrate for mechanistic studies on asymmetric catalysis. Cyclopropylthiophene can also be applied to the synthesis of nanoparticles for catalysis in organic reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Amino-6-chloro-3,4-dihydropyrimidine-4-thione is a pyridine derivative with a molecular formula of C5H7ClN2. It is soluble in water and has a melting point of 159°C. 5-Amino-6-chloro-3,4-dihydropyrimidine-4-thione can be classified as a heterocycle and is also known as 5,6,3',4'-tetrahydropyrimidinethione or 1,2,3,4,5,6,7,8,-hexahydrobenzopyrimidine. This compound has been shown to react with nitriles to form substances that have been used for spectroscopy purposes.</p>

<p>6-(4-Hydroxyphenyl)-2H-pyridazin-3-one is a monomer that is used to make polymers. The polymerization of 6-(4-hydroxyphenyl)-2H-pyridazin-3-one requires the use of solvents, such as chloroform. It is a dipolar molecule and has two moieties, which are hydroxyls and pyridazine rings. Polymerization occurs by means of polycondensation, which is a process in which two molecules react with each other to form a larger molecule. Polymers are made from copolymers, which are created by combining at least two different monomers. The temperature required for this process ranges between 50°C and 200°C, depending on the type of polymer being created. 6-(4-hydroxyphenyl)-2H-pyridazin-3-one can be used as</p>

<p>2-Bromo-4-chloro-6-methylphenol is a benzonitrile derivative that has been investigated computationally for its energies and reactivity. It has been found to be reactive in the presence of anilines, morpholine, and trifluoromethylbenzene. The experimental analysis of the gas phase reaction between 2-bromo-4-chloro-6-methylphenol and aniline show that it is activated by the amine group. In addition, 2-bromo-4-chloro-6 methylphenol reacts with morpholine and a variety of other molecules at elevated temperatures. The reactivity of this molecule has also been studied using microcalorimetry and toluene as a solvent.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>