Building Blocks

<p>1-Bromo-4-(bromomethyl)-2-chlorobenzene is a brominating agent that can be used for the preparation of alkyl halides. It reacts with sodium hydride to give the corresponding sodium alkoxide, which can be hydrolyzed to give an alcohol. The reaction product is then treated with methoxy or chloro groups, giving a 1-bromo-3-methoxy-2-chlorobenzene or 1-bromo-3-chloro-2-chlorobenzene respectively. This compound can also be used as an inhibitor in organic synthesis reactions involving hydrolysis and reductive dehalogenation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-[(3-Methoxyphenyl)amino]-1,3,4-thiadiazole-2-thiol (MTT) is an elastomer that is used for surface modification and as a monomer. It has been shown to be a conditioner for polyethylene terephthalate (PET), polyurethane, and polyvinyl chloride (PVC). MTT has also been used in the preparation of organic halide polymers. This polymer can be prepared by radical polymerization with hydroxyl groups on the backbone. The hydroxyl group can react with the active hydrogen of an ester to produce an alcohol or amine. The product of this reaction is called an organohydrogenpolymer. If this polymer is a hydroxyl copolymer, it can be modified by the addition of functional groups such as carboxylic acids or amines.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(+)-tert-Butyl D-lactate is a cyclic ester that is found in plants and animals. It is structurally similar to the natural amino acids, L-aspartate and L-valine. (+)-tert-Butyl D-lactate has been used as an ancillary for the determination of DNA sequences and has been shown to have a ring opening reaction with amido groups. This product has also been used as feedstock for the production of lactates and as a component in copolymerization reactions. !--</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-bromo-2,5-dimethoxybenzaldehyde is a synthetic compound that is an incompletely nucleophilic anionic molecule. It has been used to advance the study of aromaticity and analyzes the spectrum of compounds. 3-bromo-2,5-dimethoxybenzaldehyde has been used in the synthesis of anthracyclines and tetracyclic antibiotics. The chemical structure of 3-bromo-2,5-dimethoxybenzaldehyde includes an aryl group at one end and a tetracyclic ring system at the other end. This chemical is not active as a chemotherapeutic agent because it does not have any biological activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-2,3-dihydro-1H-indol-2-one is a chiral molecule that has two different forms: the axial form and the atropisomer. This compound is a precursor to 3-chloro-2,3,5,6-tetrahydrobenzo[b]thiophene, which can be used in the synthesis of other compounds such as atropine. It has been shown that 3-chloro-2,3,5,6-tetrahydrobenzo[b]thiophene can act as an antagonist of muscarinic acetylcholine receptors. Chloride ions are required for this reaction. This compound also reacts with titanium tetrachloride and titanium metal in the presence of boron trifluoride etherate to produce axially chiral molecules.</p>

<p>6-Chloropyrido[3,2-b]pyrazine is a chemical compound that has been shown to be a good candidate for dechlorination and debromination reactions. It can be used as an intermediate in the synthesis of potassium amides and anionically charged compounds. The product is unreactive but reactive towards reductive conditions. 6-Chloropyrido[3,2-b]pyrazine is stable at room temperature and does not react with water.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Ethyl-4-bromo-benzenamine is a preorganized molecule with a covalent amide bond that is stabilized by interactions with the macrocyclic moiety. The helical conformation of this molecule is stabilized by its substructures, which are the two N-ethyl groups and the bromine atom. The helicity of this compound is high, and it has been shown to have a yield of 100%.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Vanillic acid is a phenolic compound that can be found in vanilla and other plants. It is an important precursor for the synthesis of aromatic compounds such as ferulic acid, lignin, and coumarin. Vanillic acid has been shown to have a variety of biochemical and chemists properties, including the ability to aromatize, which means it can be used in the preparation of synthetic hormones. This compound also acts as an antioxidant by scavenging reactive oxygen species. Vanillic acid is found in two sources: pre-existing vanillin (from plants) and ferulic acid (from microbial metabolism). Vanillin is derived from coniferyl alcohol and coniferaldehyde, which are both found in poria. Ferulic acid is produced by polyporus fungi and can be converted into vanillic acid via decarboxylation.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Benzenesulfonyl)propan-2-ol is a chiral, neutral compound that is used as a heterofunctional catalyst. It is an electrophilic catalyst that can be used to catalyze hydroboration reactions. 1-(Benzenesulfonyl)propan-2-ol binds to the substrate with two bidentate interactions and participates in the reaction by donating electron density from the nitrogen atom of an allylic position. This compound is also capable of catalyzing catecholborane oxidation reactions, which are important for the synthesis of pharmaceuticals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenyl-1H-imidazole-4-carbaldehyde is an aldehyde that is used as a ligand in asymmetric synthesis. It can be used in the nitroaldol reaction to produce chiral imidazole derivatives. The compound is useful for the synthesis of molecules with high molecular weight and low reactivity, which can be further modified to produce pharmaceuticals. The compound has been shown to catalyze organic reactions, such as condensation products and stereospecific reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,2-dimethylpropanecarboximidate hydrochloride is a synthetic chemical that has been used as a reagent in organic synthesis. It was first developed in the early 1940s and was found to have hypotensive properties. The drug is a competitive inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinase. Methyl 2,2-dimethylpropanecarboximidate hydrochloride is structurally related to benzimidazole derivatives and thiones. It has an aromatic heterocyclic structure with two nonpolar groups at opposite ends of the molecule.</p>

<p>Versatile small molecule scaffold</p>

<p>Cyclopentanecarboximidamide hydrochloride is a prodrug that is metabolized to its active form, pyridoxamine. The active form inhibits the enzyme histone deacetylase, which plays a role in viral infections. Cyclopentanecarboximidamide hydrochloride has been shown to be effective against chronic liver disease and other diseases of the central nervous system. The drug also has anti-inflammatory properties and may have antiviral effects. It also inhibits the production of inflammatory mediators such as nitric oxide and prostaglandin E2 by inhibiting cyclooxygenase activity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Hexahydro-1H-pyrrolizine-7a-carbonitrile is an experimental drug that belongs to the class of medicines. It has a six-membered ring and is stable, with a molecular weight of 204. Hexahydro-1H-pyrrolizine-7a-carbonitrile has been shown to have antihistamine or anticholinergic properties, which may be due to its ability to inhibit the release of histamine from mast cells or block acetylcholine receptors in nerve endings. The mechanism for this action is unknown, but it may be related to the equilibrium between two diastereomers: one with an electron withdrawing group on nitrogen and another with electron donating groups on nitrogen. This equilibrium can be controlled by changes in temperature or pH levels.</p>

<p>4-N,4-N,6-Trimethylpyrimidine-2,4-diamine is a solvate of 4-N,4-N,6-trimethylpyrimidine and dimethyl sulfoxide. It has been characterized by X-ray diffraction analysis and the cocrystal structure with dimethyl sulfoxide. The crystal belongs to space group P2 1 2 1 2 1 2 1 . The chains are linked by hydrogen bonds. There are two hydroxy groups on the solvate molecule, as well as two cyano groups.</p>

<p>Versatile small molecule scaffold</p>

<p>8-Hydroxy-2-oxo-1,2-dihydroquinoline-5-carbaldehyde is a cyclic compound that has been identified as a metabolite of quinolones such as ciprofloxacin. It is also found in human urine and faeces. The structure of 8-hydroxy-2-oxo-1,2-dihydroquinoline 5'-carbaldehyde can be determined by spectrometric methods. This compound is the product of metabolism of ciprofloxacin and other quinolones. Ciprofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, leading to inhibition of RNA synthesis and protein synthesis. Quinolones are also metabolized to 8-hydroxy 2 -oxo 1,2 -dihydroquinoline 5'-carbaldehyde by glucuronic acid conjugation and hydrolysis. The</p>

<p>Versatile small molecule scaffold</p>

<p>4-Aminoquinoline-3-carboxylic acid is a linker that can be used to modify the structure of other molecules. It is used in the synthesis of dopamine conjugates, which are used as inhibitors for neurodegenerative diseases. 4-Aminoquinoline-3-carboxylic acid has been shown to inhibit dopamine uptake at nanomolar concentrations. These compounds have also been shown to inhibit the growth factor activity of nerve growth factor and brain derived neurotrophic factor.</p>

<p>1-Methylcyclopent-2-ene-1-carboxylic acid is a biodegradable, neutral compound that inhibits the activity of enzymes. It is used as a preservative in cosmetics and pharmaceuticals. This product is also used to prevent the formation of hippuric acid, which can be synthesized by the enzyme methyl esterification. 1-Methylcyclopent-2-ene-1-carboxylic acid is often used in conjunction with other organic acids such as citric or lactic acid to make them more effective.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Phenyl-1,3,4-oxadiazole-2-carboxamide (PDC) is a quaternary ammonium salt that has been shown to inhibit the growth of methicillin-resistant Staphylococcus aureus and other gram-negative bacteria. PDC inhibits the synthesis of proteins by binding to ribosomes in the bacterial cell wall. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme ribosome that is required for protein synthesis and cell division. PDC also has antimicrobial properties and can be used as an antibacterial agent.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Hydrazinoquinoline hydrochloride is a cation with a molecular weight of 176.2. It is cytotoxic and inhibits cancer cell growth. 4-Hydrazinoquinoline hydrochloride has been shown to be effective against lymphoid, breast, colon, and prostate cancer cells in vitro with IC50 values of 0.5 to 2 μM. This drug has been shown to bind to DNA by forming a Schiff base with the amine group of guanine residues in the DNA backbone. This binding leads to changes in DNA conformation that inhibit transcription and replication as well as protein synthesis and cell division.</p>

<p>4-(5-Formylfuran-2-yl)-N-methylbenzene-1-sulfonamide is a synthetic, antiparasitic and antibiotic drug that has been shown to possess antiviral and antifungal properties. It is an inhibitor of DNA synthesis and RNA transcription by blocking the enzyme RNA polymerase II, and also inhibits protein synthesis by inhibiting the enzyme ribosomal protein S12. 4-(5-Formylfuran-2-yl)-N-methylbenzene-1-sulfonamide is effective against both Gram positive and Gram negative bacteria, as well as yeast. The compound has been shown to be active against bacteria such as Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica serovar Typhi, Staphylococcus aureus (MRSA), Mycobacterium tuberculosis, Mycobacterium avium complex, Candida alb</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Chloro-8-nitroquinoline is an indian nitro compound that yields a greenish yellow liquid when reacted with quinaldine, which is an aromatic amino compound. The 8-nitroquinoline group in this compound has an amino group and reacts with the fungitoxicant guanidine. This class of compounds is used to control fungi such as Aspergillus and Myrothecium verrucaria. 6-Chloro-8-nitroquinoline can be hydrolyzed by strong acids or bases, yielding chloro formates.</p>

<p>4-(1H-1,2,3-Triazol-1-yl)phenol is a small molecule that has been shown to enhance the efficiency of diagnosing certain conditions. It can be used in microwells as a sensor for measuring the concentration of analytes such as antibodies, enzymes, proteins, and other compounds. This compound is immobilized on a solid surface and reacts with light to produce chemiluminescence. 4-(1H-1,2,3-Triazol-1-yl)phenol can be used as an immobilization agent for magnetic beads and also has fluorescent properties. It has been shown to inhibit hepatitis B virus replication by binding to the viral antigen. 4-(1H-1,2,3-Triazol-1-yl)phenol is also able to detect peroxide in biological fluids or luminol in animal tissue.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>