Building Blocks

<p>2-Ethoxyethane-1-sulfonyl fluoride is a fluorinated electrophile. It reacts with electron-rich aromatic compounds to form new ring structures. 2-Ethoxyethane-1-sulfonyl fluoride is used in the synthesis of polyfluoroalkyl, reactive, and pyrrole containing compounds. This compound is also used to prepare n-substituted derivatives from electron rich aromatic compounds by cycloaddition reactions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methylpentan-2-yl chloroformate is an oxytocin antagonist and vasopressin agonist. It binds to oxytocin receptors, blocking the actions of this hormone. 4-Methylpentan-2-yl chloroformate has been used in a number of formulae.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 7-hydroxy-5-oxo-2,3-dihydro-1H,5H-pyrido[3,2,1-ij]quinoline-6-carboxylate (EHTQ) is a structural analog of pyridorin A. It has been shown to have antitubercular activity in vitro and in vivo. EHTQ inhibits the growth of Mycobacterium tuberculosis by inhibiting bacterial DNA synthesis.</p>

<p>2,3,3-Trimethyl-5-carboxyindolenine (TMCI) is a fluorescent probe that can be used for the detection of hypoxic tumor tissue. It is a fluorimetric compound that reacts with nucleophilic sites on proteins and other functional groups to form conjugates. TMCI has been shown to react with cyanines, fluoroalkyl esters, and other compounds bearing electron-donating substituents. The optimum concentration of TMCI is between 0.1 and 1 mM in PBS buffer at pH 7.4 at 37°C. This probe is also sensitive to changes in its environment such as pH or temperature. TMCI has been shown to react with 2-nitroimidazole and unsymmetrical indolsium complexes, which are used as optical sensors for oxygen concentration measurements.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>tert-Butyl 2-oxocyclopentanecarboxylate (BocOcP) is a congener that has been extensively used in palladium-catalyzed asymmetric synthesis. BocOcP is an organocatalyst that can be used to activate electrophiles and nucleophiles. It has also been used in the formation of phosphonium salts and ligands. BocOcP is enantiopure, which means it has a high stereoselectivity in its reactivity. This strategy allows for the production of high-quality compounds. For example, BocOcP can be used to make imidazoles with a high degree of purity.</p>

<p>N-Cyclopentyl-amino-acetic acid ethyl ester HCl is a prophylactic antiviral drug that blocks the synthesis of viral nucleic acids. It prevents the phosphoramidate from binding to the enzyme, preventing production of the antiviral nucleoside. N-Cyclopentyl-amino-acetic acid ethyl ester HCl is used for the treatment and prophylaxis of hepatitis B virus infections. The drug does not inhibit any other type of viral or cellular RNA synthesis, but it inhibits all types of DNA synthesis in cells infected with hepatitis.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Oxa-4,9-diazaspiro[5.5]undecan-3-one is a monoamine inhibitor that has been shown to be an effective treatment for disease conditions such as Parkinson's disease. It inhibits the activity of monoamine oxidase (MAO) and prevents it from breaking down monoamines in the brain. MAO inhibitors have been shown to be effective in treating Parkinson's disease by restoring the balance of neurotransmitters in the brain. 1-Oxa-4,9-diazaspiro[5.5]undecan-3-one is also capable of binding to other receptors involved in modulating neuronal activity, such as serotonin and dopamine receptors.</p>

<p>2-Ethyl-1H-imidazole-4-carboxylic acid is a weak organic acid that is commonly used as an acid catalyst in pharmaceutical formulations. This compound is also used to produce hippuric acid, which is a preservative. The ionization of 2-ethyl-1H-imidazole-4-carboxylic acid depends on its pH. At acidic pH, it has a positive charge and at a neutral pH it has no charge. 2-Ethyl-1H-imidazole-4-carboxylic acid is also an anion at acidic pH and can form complexes with other anions such as citric or phosphoric acids. The functional theory for the formation of these complexes suggest that the carboxyl group coordinates with hydrogen atoms from the other anions, forming covalent bonds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 4-methyl-5-oxo-2,5-dihydro-1,2-oxazole-3-carboxylate is a synthetic compound. It can be obtained through the reaction of phthalimido with carbodiimide and esterification of the resultant urea with acetone. The chemical has been used in the synthesis of oxazoles.</p>

<p>4-(5-Methyl-1H-1,2,3-triazol-1-yl)aniline is a ligand that binds to the receptor for the neurotransmitter GABA. This ligand is a tool for studying the role of ion channels and their interactions with other proteins in cell biology and pharmacology. 4-(5-Methyl-1H-1,2,3-triazol-1-yl)aniline has been used as an inhibitor in research on peptides and antibodies. It is also a reagent for studies of protein interactions and receptor binding.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-(Trifluoromethyl)-1,3,4-thiadiazol-2(3H)-one is an immunoassay marker for the detection of malignant cells. This compound is a fluorinated analog of 2,4-dinitrofluorobenzene, which has been shown to be a potent chemotherapeutic agent in some preclinical studies. It has been found that 5-(trifluoromethyl)-1,3,4-thiadiazol-2(3H)one is more effective than 2,4-dinitrofluorobenzene in inducing apoptosis and cell death in cancer cells. The trifluoromethyl group on the benzene ring confers on this compound resistance to chlorine atom strategies such as chlorination and monochlorination.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(2,2-Dimethoxyethanesulfonyl)-1,1-dimethoxyethane is a model compound that can be used to study the effects of ethylene on efficiency, thermal stability, and conductivity in sulfones. 2-(2,2-Dimethoxyethanesulfonyl)-1,1-dimethoxyethane has been shown to have oxidation resistance and rechargeable properties. It also has high solubility in solvents such as ionic liquids and sulfones. This compound is not symmetrical with respect to the methoxyl groups at either end of the molecule. These features make it an interesting candidate for use in electronic devices.</p>

<p>3-Methylfuran-2-carboxamide is a carboxylic acid derivative that is used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 3-Methylfuran-2-carboxamide can be used to form amides, esters, and carbamates by reacting with ammonia or an amine. It also has bidentate character and can react with two molecules of carboxylic acid to form the corresponding ester or amidate. 3-Methylfuran-2-carboxamide is medicinally active and may be useful as an analgesic or antipyretic agent. It also has antiinflammatory properties due to its ability to inhibit prostaglandin synthesis.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(1,2,3,4-Tetrahydroquinolin-2-yl)methanamine (NQEA) is a cyclic molecule that belongs to the group of quinolines. It has been found to be active against schistosomiasis in primates and rodents. NQEA is an analogue of 2-Aminopurine and can be used as a substitute for this drug in the treatment of schistosomiasis. Nature has provided us with many analogues of NQEA that have been shown to have high activity against schistosomiasis in animals.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>6-Amino-5-nitropyridine-2-carboxylic acid is a hydroxyethyl derivative of a pyridine compound with the chemical formula C6H7NO3. This compound has an x-ray crystallographic structure that was elucidated by x-ray crystallographic studies. The crystal contains two molecules and the molecular weight is 227.37 g/mol. The compound has substituents at the benzene ring, the guanidine group, and the carboxylic group. 6-Amino-5-nitropyridine-2-carboxylic acid also has a neuraminidase inhibitory activity, which can be demonstrated in vitro using influenza virus neuraminidase as a model enzyme.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Piperazine-2-carboxamide is a synthetic drug that is used to treat tuberculosis. It binds to the mycolic acid of the bacterial cell wall, preventing it from forming an outer layer and disrupting its function. Piperazine-2-carboxamide also inhibits the synthesis of fatty acids and amines in bacteria, which are necessary for their survival. This drug can be synthesized by reacting piperazine with formaldehyde and acetamide.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Bromo-N,N-dimethylpyridin-4-amine is a chiral primary amine that can be used in cross-coupling reactions. It can be used as a nucleophilic catalyst to promote the formation of carbon-carbon bonds between two organic molecules. The reaction is catalyzed by chloride ion, which reacts with the sulfoxide group and generates an alkoxide ion. The alkoxide ion then reacts with the alcohol compound, forming a new carbon-carbon bond. This reaction is most efficient when using a primary alkylamine such as 3-bromo-N,N-dimethylpyridin-4-amine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide is a synthetic compound that has been used in pharmaceuticals and as an analog to the antibiotic cefuroxime. It is a member of the class of compounds known as n-substituted quinolines. The compound has been shown to have efficient x-ray diffraction studies and can be used as a trackable analogue in biomedical research. 2,5-Dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide also has spectroscopic properties that make it useful in determining the molecular weight of other compounds.END&gt;&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>