Building Blocks

<p>Applications 1-Heptyne can be used for cycloisomerization of alkynyl imines and alkynylation of oxiranes.<br>References Kel’in, A. V., et al.: J. Am. Chem. Soc. 123, 2074 (2001); Yamaguichi, M., et al.: Tetrahedron Lett. 24, 391 (1983)<br></p>

<p>Applications Intermediate in the production of labelled Cicletanine<br></p>

<p>Applications 2-Fluorocinnamic acid, 98% (cas# 451-69-4) is a useful research chemical.<br></p>

<p>Applications 2,4,6-Trichlorobenzoyl Chloride, can be used for the preparation of large-ring lactones in high yields. It is used for the syntheisis of cytotoxic marine natural product Amphidinolide X and Jasplakinolide (J210700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fieser, M. Reagents for Organic Synthesis New York 16, 353, (1992); Lepage, O., et al.: J. Amer. Chem. Scoi., 126 (49), 15970<br></p>

<p>Applications 2-Acetylanthracene is an organic fluorophore.<br>References Burstein, E., et al.: Photochem. Photobiol., 64, 316 (1996), Patil, S., et al.: Bioorg. Med. Chem., 15, 1212 (2007),<br></p>

<p>Applications Diethyl 2-[4-(2,2-Dicarboethoxypropyl)phenyl]-2-methyl Malonate-d3 (cas# 1346597-74-7) is a compound useful in organic synthesis.<br></p>

<p>Applications Reagent used in the preparation of many pharmaceutically active compounds such as antiulcer agents, antitumor agents, antibiotics and anxiolytics.<br>References Colabufo, N., et al.: J. Med. Chem., 51, 7602 (2008), Manfroni, G., et al.: Bioorg. Med. Chem. Lett., 19, 714 (2009),<br></p>

<p>Applications Diethyl 4-Ethoxyphenyl-(ethyl-d5)malonate (cas# 1189708-84-6) is a compound useful in organic synthesis.<br></p>

<p>Applications trans-Cyclohexane-1,4-diamine (cas# 2615-25-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Piperidin-4-one Ethylene Ketal is a derivative formed from the condensation of cyclohexanone.<br></p>

<p>Applications 4-Methylbenzyl alcohol (cas# 589-18-4) is a useful research chemical.<br></p>

<p>Applications 4,5-Dimethyl-3-isoxazolamine is an isoxazole derivative used in the preparation of a varitey of biologically active compounds such as selective ETA receptor antagonists.<br>References Murugesan, N. et al.: J. Med. Chem., 46, 125 (2003);<br></p>

<p>Applications 1,2-Dimethylisothiourea-HI (cas# 41306-45-0) is a useful research chemical.<br></p>

<p>Applications Dimethyl Malonate-d2 is an intermediate in the synthesis of Prasugrel Thiolactone-d5 (Mixture of Diastereomers). A labelled inactive metabolite of Prasugrel (P701150).<br>References Sugidachi, A., et al.: Br. J. Pharmacol., 129, 1439 (2000); Takahashi, S., et al.: J. Pharm. Sci., 97, 5434 (2008); Williams, E., et al.: Drug Metab. Dispos., 36, 1227 (2008); Hagihara, K., et al.: Xenobiotica, 39, 218 (2009);<br></p>

<p>Applications O-Toluoyl Chloride is used in the synthesis if quinolinone compounds as SARS CoV 3CLpro inhibitors. Also used in the synthesis of benzooxaboroles as orally active anti-inflammatory agents.<br>References Sun, Y. et al.: Chin. J. CHem., 31, 1199 (2013); Akama, T. et al.: Bioorg. Med. Chem. Lett., 23, 5870 (2013);<br></p>

<p>Applications Methyl 4-Methoxyphenylacetate (cas# 23786-14-3) is a useful research chemical.<br></p>

<p>Applications A metabolite of Tryptophan-niacin.<br>References Yuyama, S. et al.: Adv. Exp. Med. Biol. 294, 475 (1991).<br></p>

<p>Applications m-Toluoyl Chloride is used as a reagent in the synthesis of glycine benzamides as oral GPR139 receptor agonists. m-Toluoyl Chloride is also used in the preparation of colchicine derivatives which have potent anticancer activity and reduced P-glycoprotein induction liability.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dvorak, C.A., et al.: ACS Med. Chem. Lett., 6, 1015 (2015); Singh, B., et al.: Org. Biomol. Chem., 13, 5674 (2015)<br></p>