Building Blocks

<p>Applications Hydantoin (cas# 461-72-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Hydrazine derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications 2-Hydroxy-5-Amino-N-(2-carboxy-4-aminophenyl)benzoic Acid is an impurity from the synthesis of Mesalamine (M258100).<br>References Friedman, G., et al.: Am. J. Gastroenterol., 81, 141 (1986); Tursi A., Expert Opin. Pharmacother., 6, 69 (2005);<br></p>

<p>Applications 3-Hydroxy-O-methyl-L-tyrosine Hydrochloride is used in the preparation of tyrosine-based components of natural products such as saframycin MX1 and its analogs, which are naturally potent anti-tumor agents currently under clinical development.<br>References Schmidt, E.W.; et al.: Tetrahedron Lett, 45, 3921 (2004); Nelson, J.T.; et al.: AEM, 73, 3575 (2007)<br></p>

<p>Applications 2-Hydroxybenzyl Alcohol is a phenolic component of a part of a salix bark extract which maintains a minor anti-depressant effect. Phenolic analog with potential for anti-melanomic effect<br>References Ulrich-M. et al.: Phytomed., 19, 930 (2012); Vad, N. et al.: Chem-Biol. Int., 183, 462 (2010);<br></p>

<p>Applications 2'-Hydroxybiphenyl-3-carboxylic acid<br></p>

<p>Applications H-PRO-GLU-OH (cas# 67644-00-2) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 4-Hydroxybutyric Acid Methyl Ester is a derivative of 4-Hydroxybutyric Acid (H833015). A reactant used in the preparation of 4-aminothiazolyl analogs of natural product GE2270 A, useful against Clostridium difficile infection.<br>References LaMarche, M. et al.: J. Med. Chem., 55, 2376 (2012)<br></p>

<p>Applications 4-Hexen-1-ol, (4E)- (cas# 928-92-7) is a useful research chemical.<br></p>

<p>Applications 2-Hydroxyisobutyric Acid is used as a reagent in the preparation of fully functionalized tetronic acids. Also used in the synthesis of bioisosteres of trimethadione, N-derivative-1,2,3-oxathiazolidine-4-one-2,2-dioxides from α-hydroxyamides which display anticonvulsant activity.<br>References Prousis, K., et al.: Tetrahedron, 71, 8637 (2015); Pastore, V., et al.: Bioorgan. Med. Chem., 21, 841 (2013);<br></p>

<p>Applications 3-Hydroxyindole is a mutation product of toluene-4-monooxygenase (T4MO), that gets spontaneously converted to indigo. Used in the preparation of indolyl-oxadiazoles with anticonvulsant activity.<br>References Rajak, H. et al.: Int. J. Pharm. Sci. Nanotech., 2, 661 (2009); McClay, K. et al.: Appl. Environ. Microbiol., 71, 5476 (2005); Berry, A. et al.: J. Ind. Microbiol. Biotech., 28, 127 (2002)<br></p>

<p>Applications 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.<br>References Yamazaki, Y. et al.: Zeitsch. Naturforsch. C: J. Biosci., 65, 49 (2010); Kay, W.W. et al.: Gen. Pharmacol., 8, 201 (1977); Ghebregzabher, M. et al.: J. Chrom. Biomed. Appl., 222, 191 (1981);<br></p>

<p>Applications 1-(4-Hydroxyisoxazole)-carboxylic Acid (cas# 178316-77-3) is a compound useful in organic synthesis.<br></p>

<p>Applications β-Hydroxyisovaleric Acid is a metabolite of the essential amino acid Leucine and is synthesized in the human body. Studies suggest that β-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated β-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nissen, S. et al.: J. Appl. Physiol., 81, 2095 (1996); Wilson, G.J. et al.: Nutrit. Metab., 5, 1 (2008); Mock, D.M. et al.: Am. J. Clin. Nutrit., 76, 1061 (2002);<br></p>

<p>Applications 2-hydroxy-5-iodobenzoic Acid is a reagent in various organic chemical reactions leading to pharmaceutical compounds. It is involved in the synthesis of labelled benzamide analogs for tumor imaging as well as the synthesis of the dye, Congo Red, for biological analyses.<br>References Tu, Z. et al.: J. Med. Chem., 50, 3194 (2007); Sellarajah, S. et al.: J. Med. Chem., 47, 5515 (2004);<br></p>

<p>Applications 1,1-Dimethoxycyclohexane (cas# 933-40-4) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxymandelic Acid (cas# 17119-15-2) is a compound useful in organic synthesis.<br></p>