Building Blocks

<p>Applications 5-Chlorovaleric acid is used in the synthesis of β-cyclodextrins linked with a cyclohexyl group via an aza-Wittig reaction.<br>References Li, D. B., et al.: Tetrahedron, Lett., 43, 1871 (2002);<br></p>

<p>Applications 5-Chlorovaleronitrile is used as a reagent in the synthesis of cyanoguanidine derivatives which exhibit dual histamine H1 and H2 receptor antagonist activity. Also used in the synthesis of purine derivatives which exhibit antimicrobial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kinali-Demirci, S., et al.: Med. Chem. Res., no vol., no pp. (2014); Sadek, B., et al.: Molecules, 18, 14186 (2013)<br></p>

<p>Applications 4-Fluorobenzoic Acid Methyl Ester, is an organic fluorinated building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of Blonanserin (B595850).<br>References Wang, J., et al.: Zhongguo Yiyao Gongye Zazhi, 40, 247 (2009);<br></p>

<p>Applications 5-Chloro-2-methylphenol can be used in the preparation of dichlorotoluqinones.<br>References James, C., et al.: J. Org. Chem., 16, 328 (1951)<br></p>

<p>Applications 1,3-Adamantanediol is used in the synthesis of novel dimethacrylate as possible dental monomers for dental resin mixtures.<br>References Wang, K. et al.: Mat. Sci. Eng. Mat. Biol. Appl., 32, 1141 (2012); Horino, Y. et al.: J. Mol. Catal. A. Chem.,<br></p>

<p>Applications Pentaerythritol is a compound most commonly used in cosmetics (in its rosinate form). It is used as a skin conditioning agent (used as part of a cream base in lotions), and is also used to increase viscosity of cosmetic formulations.<br>References Andersen, F.: J. Am. Coll. Toxicol., 13, 395 (1994); Dhanorkar, V., et al.: J. Cosm. Sci., 53, 199 (2002); Lanigan, R.: Int. J. Toxicol., 17, 83 (1998)<br></p>

<p>Applications 2-isobutylthiazole (cas# 18640-74-9) is a useful research chemical.<br></p>

<p>Applications 1-(3-ACETYL-2-HYDROXY-5-METHYL-PHENYL)-ETHANONE (cas# 55108-28-6) is a useful research chemical.<br></p>

<p>Stability Volatile<br>Applications 5-Fluoro-1-pentyne use as a reactant/reagent for preparation of glutamic acid-based peptidomimetic prostate-specific membrane antigen binding agents for imaging use.<br>References Wang, E., et al.: PCT Int. Appl., WO 2013028664 A1 20130228 (2013)<br></p>

<p>Stability Hygroscopic<br>Applications 2-Chloromandelic acid<br></p>

<p>Applications 3-Penten-1-yne is used in the preparation of aliphatic and terminal alkynes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Bromohexane is a very useful synthetic intermediate for pharmaceuticals and organic chemicals. It can be used to react with Mg to prepare Grignard reagents which play an important role in formation of carbon-carbon bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tamura, M., et al.: Synth., 6, 303 (1971); Asami, M., et al.: Chem. Lett., 8, 1221 (1985); Akiba, K., et al.: Tetrahedr. Lett., 23, 3935 (1982)<br></p>

<p>Applications Cinacalcet-d4 Hydrochloride is a labeled analogue of Cinacalcet Hydrochloride (C441800), the (R) enantiomer of Cinacalcet which is used in clinical trial in secondary hyperparathyroidism.<br>References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003); Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004);<br></p>

<p>Applications Cinchophen and its derivatives can show antipyretic, analgesic, anti-oxidative, and anti-inflammatory properties.<br>References Xu, Bo., et al.: Beijing Yike Daxue Xuebao, 29(5), 438-439 (1997); Ibrahim, S. E., et al.: Mansoura J. Pharm. Sci., 6(2), 19-24 (1990); Mishra, Pradeep., et al.: Indian J. Pharm. Sci., 50(5), 269-271 (1988); Kononenko, L. I., et al.: Zhurnal Analiticheskoi Khimii, 30(9), 1716-19 (1975)<br></p>

<p>Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.<br></p>