Building Blocks

<p>Applications 3-(Hydroxymethyl)Benzamide (cas# 126926-34-9) is a useful research chemical.<br></p>

<p>Applications DL-Homocysteine is an allosteric antagonist at the dopamine d2 receptors. Mainly, L-Homocysteine (H591950) exists naturally and is recycled into methionine or converted into cysteine.<br>References Agnati, L. et al.: J. Proteome Res. 5, 3011 (2006); Stipanuk, M. et al.: Ann. Rev. Nutrition., 24, 539 (2004);<br></p>

<p>Applications dl Homocysteine Thiolactone Hydrochloride (cas# 6038-19-3) is a compound useful in organic synthesis.<br>Chemical Name: dl Homocysteine Thiolactone Hydrochloride (cas# 6038-19-3) is a compound useful in organic synthesis.<br></p>

<p>Applications An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics.<br>References Knox, W.E., et al.: Biochem. J., 49, 686 (1951), LaDu, B.N., et al.: J. Biol. Chem., 217, 777 (1955)<br></p>

<p>Applications Glutamine analog.<br>References Hellberg, S., et al.: J. Med. Chem., 30, 1126 (1987), Blondelle, S., et al.: Antimicrob. Agents Chemother., 38, 2280 (1994), Jiracek, J., et al.: J. Biol. Chem., 270, 21701(1995),<br></p>

<p>Stability Hygroscopic<br>Applications Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.<br>References McRee, D., et al.: J. Struct. Biol., 125, 156 (1999), Wang, L., et al.: Science, 292, 498 (2001), Ioerger, T., et al.: Methods Enzymol., 374, 244 (2003),<br></p>

<p>Applications Tazarotenic Acid Methyl Ester is a tazarotene (T010050) related compound, which functions as an acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>

<p>Applications 3-Hydroxyindole is a mutation product of toluene-4-monooxygenase (T4MO), that gets spontaneously converted to indigo. Used in the preparation of indolyl-oxadiazoles with anticonvulsant activity.<br>References Rajak, H. et al.: Int. J. Pharm. Sci. Nanotech., 2, 661 (2009); McClay, K. et al.: Appl. Environ. Microbiol., 71, 5476 (2005); Berry, A. et al.: J. Ind. Microbiol. Biotech., 28, 127 (2002)<br></p>

<p>Applications 5-Hydroxyindole is a hydroxylated indole used as a building block in the preparation of various pharmaceutical compounds such as indole based neurochemicals. 5-Hydroxyindole is a metabolite of Tryptophan (T894800). 5-Hydroxyindole displayed weak inhibitory activity on human melanoma tyrosinase. 5-Hydroxyindole also showed inhibition of serotonin transport by blood platelets.<br>References Yamazaki, Y. et al.: Zeitsch. Naturforsch. C: J. Biosci., 65, 49 (2010); Kay, W.W. et al.: Gen. Pharmacol., 8, 201 (1977); Ghebregzabher, M. et al.: J. Chrom. Biomed. Appl., 222, 191 (1981);<br></p>

<p>Applications 1-(4-Hydroxyisoxazole)-carboxylic Acid (cas# 178316-77-3) is a compound useful in organic synthesis.<br></p>

<p>Applications β-Hydroxyisovaleric Acid is a metabolite of the essential amino acid Leucine and is synthesized in the human body. Studies suggest that β-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated β-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nissen, S. et al.: J. Appl. Physiol., 81, 2095 (1996); Wilson, G.J. et al.: Nutrit. Metab., 5, 1 (2008); Mock, D.M. et al.: Am. J. Clin. Nutrit., 76, 1061 (2002);<br></p>

<p>Applications 2-hydroxy-5-iodobenzoic Acid is a reagent in various organic chemical reactions leading to pharmaceutical compounds. It is involved in the synthesis of labelled benzamide analogs for tumor imaging as well as the synthesis of the dye, Congo Red, for biological analyses.<br>References Tu, Z. et al.: J. Med. Chem., 50, 3194 (2007); Sellarajah, S. et al.: J. Med. Chem., 47, 5515 (2004);<br></p>

<p>Applications 3-Hydroxymandelic Acid (cas# 17119-15-2) is a compound useful in organic synthesis.<br></p>