Building Blocks

<p>Stability Hygroscopic<br>Applications (2-Chlorothiazol-5-yl)methanamine is a metabolite of Thiamethoxam (T344180), a neonicotinoid insecticide.<br>References Kemakar, R., et. al.: J. Agr. Food Chem., 57, 6369 (2009); Oliver, J., et al.: J. Environ. Horticult., 28, 135 (2010); Ghosh, A., et al.: J. Entomol. Res., 34, 35 (2010); Chem. and Eng. News 90: 10 (2012)<br></p>

<p>Applications 7-Methoxy-4-methylcoumarin (cas# 2555-28-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Methylcatechol is a potent inducer of nerve growth factor (NGF) synthesis in vitro and in vivo.<br>References Kaechi, K., et al.: J. Pharmacol. Exp. Ther., 272, 1300 (1995); Hanaoka, Y., et al.: J. Neurol. Sci., 122, 28 (1994)<br></p>

<p>Impurity Diacerein Impurity C<br>Stability Hygroscopic<br>Applications Found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves.A potential antioxidant resource: endophytic fungi from medicinal plants . Diacerein Impurity C<br>References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980), Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982), Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983),<br></p>

<p>Applications ethyl 2-azidoacetate (cas# 637-81-0) is a useful research chemical.<br></p>

<p>Applications 1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a Solifenacin (S676700) intermediate. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline had been detected in parkinsonian human brain. 1-Phenyl-1,2,3,4-tetrahydroisoquinoline maybe a candidate for endogenous MPTP-like neurotoxin since it is a structural analogue of MPTP which produces parkinsonism in humans.<br>References Kajita, M. et al.: J. Chrom. B Biomed. Appl., 669, 345 (1995);<br></p>

<p>Stability Hygroscopic<br>Applications Diazolidinyl urea is an antimicrobial agent.<br></p>

<p>Applications 3-Methoxycatechol is used to prepare polyphenolic deoxybenzoins as potential antioxidants and tyrosinase inhibitors.<br>References Ng, L., et al.: Bioorg. Med. Chem., 17, 4360 (2009)<br></p>

<p>Applications 4-Chlorobenzonitrile<br></p>

<p>Applications (2E)-Decenal is a useful starting material for organic synthesis.<br></p>

<p>Applications Cinoxate is an organic compound used as an ingredient in some types of sunscreens. Cinoxate is an ester formed from methoxycinnamic acid and 2-ethoxyethanol. Cinoxate is a slightly yellow viscous liquid that is insoluble in water, but miscible with alcohols, esters, and vegetable oils.Cinoxate protects skin against the sun by absorbing UV-A and UV-B rays.<br>References Delattre., et al.: Enzyme Microb. Tech., 41, 250 (2007); Fukuoka, T., et al.: Oleoscience, 9, 127 (2009);<br></p>

<p>Applications 2,​4-​Diaminoanisole is a component and degredation product of azo dyes in fabrics and textiles. Azo dyes occasionally produce carcinogenic effects and environmental reproductive toxicology. Dyes and metabolites, Environmental TestingEnvironmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nguyen, A. et al.: J. Env. Sci. Health A., 51, 744 (2016);<br></p>

<p>Applications Formaldehyde is used in various organic synthesis and reactions. It is used in the textile industry in the area of crosslinking molecules to vary the properties of cotton fabrics (1). It can help improve the water resistance of biodegradable collagen films (2). In the food industry it is used to reinforce and improve packaging of meats and produce. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Liang, T. et al.: Text Res. J. 1992 Sep:62(9) 547-5512. Sommer, I. et al.: J. Appl. Polym. Sci. 2012 Sept:125(S2) ppE27-41<br></p>

<p>Applications 1,3-Diacetin is a derivative of Triacetin (T720850) which is used as a food additive and flavorings. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>

<p>Applications 1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.<br>References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009); Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008); Yuan, Y., et al.: Zhongguo Yiyao Gongye Zazhi, 43, 5 (2012)<br></p>

<p>Applications Fomepizole is an alcohol dehydrogenase inhibitor. It also inhibits CYP2E1 activity.<br>References Samuelson, J., et al.: Arch. Med. res., 23, 31 (1992); Shahraki, J., et al.: Iranian J. Pharm. Res., 12, 829 (2013); Thapallya, S., et al.: Autophagy, 10, 677 (2014)<br></p>