Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Pyridinecarboxylic Acid Ethyl Ester is a compound that belongs to the group of pyridinecarboxylic acids. It is a metabolite of nicotinamide, which is converted to 4-pyridinecarboxylic acid ethyl ester by esterases in the intestine. Nicotinamide is an important component of the vitamin B3 and has been shown to be effective for treating autoimmune diseases such as rheumatoid arthritis. 4-Pyridinecarboxylic Acid Ethyl Ester may have similar effects on inflammatory bowel disease and alopecia areata. The reaction mechanism of this compound has not been elucidated, but it has been shown to inhibit amyloid protein production in rat intestines. Hydroxyl groups on the side chain likely play a role in hydrogen bonding interactions with receptors in inflammatory bowel disease and alopecia areata.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-2-methyl-5-nitroaniline is an organic compound with the chemical formula C6H4ClNO2. It is a nitro derivative of aniline. 4-Chloro-2-methyl-5-nitroaniline is a white solid that is soluble in water, alcohols, and ethers. It has a melting point around 206 °C and decomposes at temperatures over 350 °C. This compound can be obtained by reacting hydroxylamine with nitrous acid and chlorinating 2,5-dimethylaniline. The sequence of reactions can be summarized as follows: hydroxy group to nitro group, nitro group to methyl group, methyl group to acetyl or acetylamino, acetyl or acetylamino to acetylation or methylation, transformation from hydroxyl group to amino group and esterification from acid hydrazide to acid group.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole is a recombinant protein that binds to the ribosomal protein L11. It has been shown to inhibit the biosynthesis of the bacterial cell wall and therefore inhibit replication of the bacterial genome. 3-[(2-Methyl-2-propen-1-yl)thio]-5H-1,2,4-triazino[5,6-b]indole also inhibits the synthesis of proteins essential for cell division. This compound has been shown to bind to ribosomes in both prokaryotic and eukaryotic cells. It may have potential as an inhibitor of cancerous cells because it inhibits protein synthesis in mammalian cells.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pyrazolo[1,5-a]pyridin-4-ol is a heteroaromatic compound that acts as an inhibitor of phosphodiesterase (PDE). It prevents the breakdown of cyclic nucleotides and thus leads to increased levels of cAMP and cGMP. Pyrazolo[1,5-a]pyridin-4-ol has been shown to have bronchodilatory activity in animal models. The drug also inhibits the production of inflammatory mediators such as prostaglandins by inhibiting cyclooxygenases. In addition, pyrazolo[1,5-a]pyridin-4-ol has been shown to be a potential PDE inhibitor replacement for the more commonly used PDE inhibitors such as sildenafil and tadalafil. However, due to its lack of stereochemistry and its bicyclic chemical structure, pyrazolo[1,5-a]</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Tetramethyl-1,3-cyclobutanediol is a diacid that can be used as a monomer for the production of polyesters. It has conformational properties that are different from other diols. Tetramethyl-1,3-cyclobutanediol is soluble in hydrochloric acid and reacts with coatings containing dibutyltin oxide to produce residues. This chemical also reacts with copper oxide, resulting in the formation of copper cyclohexanol and dibutyltin oxide. Tetramethyl-1,3-cyclobutanediol is able to react with carboxylic acids to form esters. This compound has been shown to be employed in the synthesis of polycarboxylic acids such as adipic acid and sebacic acid. Tetramethyl-1,3-cyclobutanediol has been used in the production of polyester resins by reacting with ethylene glycol and tere</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylbenzo[b]thiophene-2-carboxylic acid (MBTCA) is a heterocyclic compound that is an intermediate in the synthesis of 3-methylthiophene-2-carboxylic acid, a precursor to other drugs. MBTCA is an aerobic, nonpolar compound that has shown antimicrobial activity against some bacteria and fungi. It also has been shown to have practicality as a biomolecular probe for methyl groups in organic solvents. MBTCA can be synthesized by nitration of benzene in the presence of sulfur and sulfoxides. This reaction produces nitrobenzene, which can then be oxidized by potassium permanganate or hydrogen peroxide to produce MBTCA. The most common isomer of MBTCA is 2-(3,5-dimethoxybenzylidene)tetrahydrofuran, with three methyl groups on the</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>