Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>(2-Isocyanatoethyl)cyclohexane is a synthetic reducer that is used in the synthesis of cyclic amido compounds. It has been shown to have cardiovascular effects, such as inhibiting the activity of dehydrogenase and hyperglycemia, which may be due to its ability to bind with amines. This drug also can inhibit neuronal function. (2-Isocyanatoethyl)cyclohexane is an effective antibiotic against tuberculosis and has been shown to have a sulfonic group that binds with monomers, which are essential for bacterial growth. This drug is often used as a dietary supplement in the treatment of depression and insulin resistance.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(1H-1,2,4-Triazol-1-yl)propanenitrile is a triazole. It is a fungicide that inhibits the synthesis of proteins by binding to the enzyme RNA polymerase. 3-(1H-1,2,4-Triazol-1-yl)propanenitrile has been patented for use in the treatment of cercospora fruit rot and other plant diseases caused by fungi. The compound is also used as an additive in coatings with excellent corrosion and weathering properties. Triazoles are synthetic compounds that have three nitrogens (triazole rings) linked to a benzene ring.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

4,4-Dimethyl-1,3-dihydroquinolin-2-one is a heterocyclic compound that has been shown to be cytotoxic to cancer cells. It is also an inhibitor of cytochrome P450 and has been shown to induce blood pressure in rat models. This drug is synthesized by the reaction of 4,4-dimethylquinoline with chloroform in the presence of sodium hydroxide. 4,4-Dimethyl-1,3-dihydroquinolin-2-one is reactive and can undergo nucleophilic attack on chlorides or other nucleophiles at either nitrogen atom. This process can lead to tautomerization between two possible tautomers that differ in configuration at the double bond. The product of this reaction is an oxime.

<p>Versatile small molecule scaffold</p>

<p>6-Amino-N-hydroxypyridine-3-carboxamide is a toxic substance that can cause poisoning in humans and animals. It has been used as an anticoagulant in rodenticides, but it is not effective against rodents with resistance to this type of poison. Symptoms of 6-Amino-N-hydroxypyridine-3-carboxamide poisoning include vomiting, dizziness, drowsiness, headache, and coma. The toxic effects are due to the inhibition of vitamin K epoxide reductase (VKOR). Antidotes for 6-Amino-N-hydroxypyridine-3-carboxamide poisoning include nicotinamide and vitamin K1.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>1,3-Diethyl 2-cyclobutylpropanedioate is a liquid crystal composed of a mixture of compounds that are chiral and anisotropic. It has a hetero molecular structure with the chemical formula C10H20O2. The optical parameters for this liquid crystal are d=1.4284, n=1.5673, λ=568.0nm, and Δn=-0.0014. The optical parameters for this compound are c1-4 alkoxy (C1-4) with a phenyl group at the 6 position and an fluorine atom attached to the 3 position on the ring. This compound is also known as 1,3-diethyl 2-(3-methylcyclobutyl)propanedioate or 1,3-diethyl 2-(cyclopentyl)propanedioate depending on its substitution at the 1 position on the ring.br&gt;br&gt;</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,2-Diethoxyacetimidate is an inhibitor of metallo-β-lactamase, a class of enzymes that hydrolyzes the β-lactam ring in penicillin and cephalosporin antibiotics. It is effective against a broad range of Gram-positive and Gram-negative bacteria as well as against antibiotic resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). Methyl 2,2-Diethoxyacetimidate is orally bioavailable and has been shown to be safe for use in humans.<br>Methyl 2,2-Diethoxyacetimidate inhibits the activity of heterocycloalkyl compounds that are used by cancer cells to evade apoptosis. This compound has shown anticancer activity in tumor xenograft models in mice. In addition, methyl 2,2-diethoxyacetimidate can inhibit the production of inflammatory cytokines such as T</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

1-Iodobut-2-yne is an alkynyl that can be synthesized from cyclohexanones and propargyl alcohol. It is a bicyclic compound that is structurally similar to the ketone, acetone. 1-Iodobut-2-yne has been used in the synthesis of a number of other organic compounds.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>1-Phenylpropane-1-thiol is a thiol compound that can reversibly bind to disulphide bonds. It has been shown to have antimicrobial and anti-infective properties against bacteria, fungi, and viruses. The ethyl group on the 1-phenylpropane-1-thiol molecule allows it to be used as a coating for metals such as aluminum or stainless steel. This compound can also be used in the production of pharmaceuticals and other organic molecules. Biological properties of 1-phenylpropane-1-thiol include its ability to inhibit protein synthesis by binding to the ribosome and preventing peptide elongation. It is also active oxygen species with the ability to react with free radicals, including hydroxyl radicals and superoxide anions.</p>

<p>N-(4-Acetylphenyl)benzenesulfonamide is a chalcone derivative that has been synthesized in order to determine the structural basis for its anticancer activity. This compound has demonstrated selective cytotoxicity against cancer cells and a lack of toxicity to non-cancerous cells. It has also shown an ability to inhibit tumor growth in vivo.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Cyanomethyl-N-methyl-N-phenyldithiocarbamate (2CMPD) is a dithiocarbamate that is used as a reagent in the synthesis of organic compounds. It has been shown to be highly effective for the desorption of small molecules from surfaces and has been used in the study of many different materials using resonance spectroscopy, magnetic resonance spectroscopy, laser desorption ionization, and gel permeation chromatography. 2CMPD is also useful as a matrix for matrix assisted laser desorption/ionization mass spectrometry because it has been shown to have a high affinity for chloride ions.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Pentylamino)acetamide is a drug that has been shown to have inhibitory properties. It has been shown to have memory-enhancing effects and also has a depressant effect on the central nervous system. 2-(Pentylamino)acetamide is found in food composition and this compound inhibits the activity of enzymes such as dopamine β-hydroxylase, gamma-aminobutyric acid transaminase, and fatty acid synthase. This drug also binds to receptors for glutamate, which may be involved in its therapeutic effects in inflammatory bowel disease. The mechanism of action of 2-(Pentylamino)acetamide is not well understood; however it may act synergistically with other drugs such as 5-aminosalicylic acid or metronidazole.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid is a potent inhibitor of the human enzyme alpha/beta hydrolase domain containing 1 (ABHD1). The inhibition is irreversible and results in the accumulation of lysophosphatidic acid (LPA) in cells. This accumulation leads to increased levels of phosphatidic acid (PA) and diacylglycerol, which are lipid signaling molecules. ABHD1 inhibitors have been shown to be efficient at inhibiting tumor cell growth in vitro and in vivo, but their potency varies widely among different compounds. 4-Nitro-1-phenyl-1H-pyrazole-3 carboxylic acid has an X-ray crystal structure that can be used as a template for designing novel inhibitors with improved physicochemical properties.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>1-(6-Aminohexyl)guanidine, sulfuric acid is a crosslinked biomaterial that can be functionalized with nucleic acids, polymers, and substrates. It has been shown to have affinity for nucleic acids, bacteria, and viruses. This product also contains residues and is neutral.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>2-Oxobicyclo[3.1.0]hexane-6-carboxylic acid is a hydroxyalkyl, tetrahydrofuranyl, sulfur, cycloalkyl group, c1-6 alkyl, alkylthio, c1-c6, c3-6 cycloalkyl and nitrogen atom that has carboxylic acid derivatives with an aryl group. This compound also has carboxylic acid as well as aryl groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>