Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Octane-1-sulfonamide (OSA) is a glycol ether that is used as a reagent for biological samples. It reacts with the hydroxyl group on proteins, which causes the compounds to become more hydrophobic and interact with each other. The OSAs are also reactive with fatty acids, which leads to cross-linking of cell membranes. This interaction may be related to the low light activity of OSA. Octane-1-sulfonamide can also bind cationic polymers, which may be useful in ophthalmic drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,6-dichloropyridine-3-carboxylate is a carboxylic acid that can be synthesized by reacting 2,6-dichloropyridine with an acetyl chloride. It has been used in the synthesis of dopamine D2 receptor antagonists. The sulfoxide group in this compound may undergo alkaline hydrolysis to yield an anion and a nucleophilic adduct. This carboxylic acid also reacts with triethylamine to form esters. In addition, methyl 2,6-dichloropyridine-3-carboxylate is regioselective for the alpha position when it reacts with methyltetrahydrofuran.</p>

<p>6-Chloro-2-methoxynicotinic acid is a ketone that reacts with chlorine in the presence of light to form chlorinated products. It is a versatile intermediate for the synthesis of various compounds. 6-Chloro-2-methoxynicotinic acid is used in the synthesis of naphthacene, which is a precursor to dyes and pharmaceuticals. The reactivity of this compound depends on substituents located at the 2 position. Substituents cause sterically hindering effects and lead to different geometries and reactivities, such as attack by chlorine or substitution by hydrogen.</p>

<p>2-Methoxy-4,6-dimethylnicotinonitrile is a photoreactive compound that reacts with UV light to produce an adduct. The 1-cyanonaphthalene group in 2-methoxy-4,6-dimethylnicotinonitrile undergoes a photochemical reaction to form an adduct with the benzene ring. It is postulated that the dimer and x-ray structural analysis of 2-methoxy-4,6-dimethylnicotinonitrile are stable and pyridine can be used as a solvent.</p>

<p>2-Amino-4-(aminooxy)butanoic acid dihydrochloride is a cyclization product of the antibiotic cycloserine. It has been synthesised from 2-amino-4-oxobutanoic acid by the addition of hydrochloric acid and then heated to reflux for 20 hours. The purity of this product is &gt;98%.<br>2-Amino-4-(aminooxy)butanoic acid dihydrochloride has been shown to be a homologue of canaline, which is an antibiotic used in the treatment of tuberculosis. This compound also has antibacterial activity, although it is less potent than cycloserine.</p>

<p>(2E,4E)-Hepta-2,4-dienoic acid is an organic compound that belongs to the group of quinoline derivatives. It is a colorless liquid at room temperature and is soluble in organic solvents. This compound can be used as a dehydrohalogenating agent in the synthesis of mappicine and camptothecin derivatives. (2E,4E)-Hepta-2,4-dienoic acid can also react with ketocarboxylic acids to form carotenoid compounds. The chemical formula for this molecule is C8H10O3.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Pyridin-3-yl)propanoic acid is a quinoline derivative that has been shown to be safe and effective in clinical trials. It is being tested for the treatment of type 2 diabetes, obesity, and metabolic syndrome. The oral administration of this drug inhibits the activity of dipeptidyl peptidase-4 (DPP-4), which is an enzyme involved in the degradation of insulin. This inhibition leads to increased levels of insulin in the blood and improved glucose tolerance. 2-(Pyridin-3-yl)propanoic acid interacts with other drugs through competitive inhibition at their binding sites on enzymes. Optimization experiments have shown that it can interact with pyridine compounds, which are found in many drugs including acetaminophen and caffeine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Carbamoylamino)-3-(thiophen-2-yl)propanoic acid is an organic compound that is used as a building block in the synthesis of complex carbohydrates. It has been shown to be a substrate for the modification of oligosaccharides and glycosylations, where it can be modified with methylation, fluorination, or click chemistry. 3-(Carbamoylamino)-3-(thiophen-2-yl)propanoic acid is also used in the synthesis of polysaccharides such as saccharide and glycoproteins. This product has high purity and is available at custom synthesis scales.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Ethyl-3-hydroxy-1,2-dihydropyridin-2-one (EHDP) is a potential therapeutic agent for the treatment of Alzheimer's disease. It has been shown to inhibit the formation of amyloid beta peptides that are thought to cause Alzheimer's disease. EHDP may be effective in preventing or slowing the progression of Alzheimer's disease by blocking the production of amyloid beta peptides and by preserving long term potentiation in neurons. This compound is also capable of crossing the blood brain barrier and has been shown to bind to citric acid at high affinity.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(Hydroxymethyl)-2(1H)-quinolinone is a potent GABA antagonist with a low micromolar range of activity. It is used as a tool to evaluate the profile of GABA receptors and their kinetics, as well as to study the antagonistic activity at these receptors. 3-(Hydroxymethyl)-2(1H)-quinolinone has been shown to have antagonistic properties against glutamate and glycine receptors, although it does not bind to benzodiazepine or barbiturate binding sites. This drug has proapoptotic properties, which relates to its ability to induce neuronal cell death by apoptosis. 3-(Hydroxymethyl)-2(1H)-quinolinone also photolyzes in the presence of light and can be used for photodynamic therapy, which is an effective treatment for brain cancer.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Carboxymethyl)phenylboronic acid is a corrosion inhibitor that is used in the production of polyvinyl chloride, polyvinyl alcohol, and ethylene glycol. It can be used as an additive to lubricating oils and fuels. 4-(Carboxymethyl)phenylboronic acid has been shown to inhibit the corrosion of lead in hydrochloric acid solutions. This compound has also been shown to inhibit the formation of silicon-sulfide complexes in polystyrene and polyvinyl chloride.</p>

<p>Versatile small molecule scaffold</p>

<p>3-(2-Chloroethyl)imidazolidine-2,4-dione (3CI) belongs to the class of intramolecular corroborating advances. It is a chemical compound that can be used in kinetic analyses of pathways and mechanisms. 3CI has been shown to lower the activation energy for reactions and quantification of benzyl yields. The mechanism of action is through the lowering of activation energies and by quantifying yields.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Methoxy-pyridine-2-carboxylic acid amide is a multinuclear compound that can be classified as a pyridine molecule. It has anions that are capable of hydrogen bonding, which is important for its interaction with other molecules. The compound also mimics the properties of benzene and cyclic compounds. 4-Methoxy-pyridine-2-carboxylic acid amide has been shown to have magnetic properties and catalytic activity in the presence of counterion, such as hydrogen ions or sodium hydroxide.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methylcyclohexane-1-carbonitrile is a phenoxide that is formed by the reaction of silicon and carbon. It has an empirical formula of C6H4O2NSi and a molecular weight of 122.14 g/mol. 2-Methylcyclohexane-1-carbonitrile has been found to yield a variety of products, including carbons, phenol, and cyclohexanol.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-5-ethylpyridine is a chemical compound that belongs to the class of heterocyclic compounds. It is used as a catalyst in catalytic reduction and metabolic rate studies. This compound has been found to increase the production of flavopereirine, an important intermediate in the metabolism of plant polyphenols. 2-Chloro-5-ethylpyridine has also been shown to have an agonistic effect on the long term treatment of diabetes mellitus type 2. This agent has been shown to optimize yields and reduce hypoglycemic effects in animal models.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>