Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-{[4-(Pyridin-2-yl)piperazin-1-yl]methyl}aniline is an electron paramagnetic resonance (EPR) active compound. It inhibits the corrosion of metals, such as iron, by a process that involves the release of electrons. This compound has been shown to be effective at inhibiting the activity of various enzymes in vitro, including those involved in DNA replication and transcription. 4-{[4-(Pyridin-2-yl)piperazin-1-yl]methyl}aniline is also fluorescent and can be used to monitor the progress of cellular processes using fluorescence microscopy.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(4-Aminopiperidin-1-yl)-2-phenylbutan-1-one is a peptide that belongs to the group of activators. It has been shown to have an inhibitory effect on ion channels, such as potassium channels and calcium channels. The pharmacological properties of 1-(4-aminopiperidin-1-yl)-2-phenylbutan-1-one are not yet known.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N'-Hydroxy-3-(morpholin-4-ylmethyl)benzene-1-carboximidamide is a potent and selective inhibitor of the human EP4 prostaglandin receptor. The compound inhibits G protein activation, cAMP accumulation and calcium mobilization in cells expressing the EP4 receptor. N'-Hydroxy-3-(morpholin-4-ylmethyl)benzene-1-carboximidamide is used as a research tool to study the function of prostaglandin receptors and their role in various biological processes such as inflammation, immune response, signal transduction, and cell proliferation.<br>N'-Hydroxy-3-(morpholin-4-ylmethyl)benzene-1-carboximidamide has been shown to be a potent inhibitor of the human EP4 prostaglandin receptor. This inhibitor blocks G protein activation, cAMP accumulation and calcium mobilization in cells expressing this receptor. N'-Hydoxy 3-(morph</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(5-Bromopyridin-2-yl)sulfanyl]benzoic acid is a synthetic sulfonamide analog with high affinity for the potassium channel. The compound binds to the Kv1.3 channel and blocks ion flow, which may lead to inhibition of neuronal transmission in the central nervous system.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-(2,3-Dimethoxyphenyl)-1,3,4-oxadiazol-2-amine is a potent inhibitor of protein interactions. It binds to the active site of target proteins and prevents them from interacting with their ligands. 5-(2,3-Dimethoxyphenyl)-1,3,4-oxadiazol-2-amine is used as a research tool for studying the role of various proteins in cells. This molecule can be used to activate or inhibit ion channels, receptors, and other cellular targets that are important for cell function. 5-(2,3-Dimethoxyphenyl)-1,3,4-oxadiazol-2-amine has a molecular weight of 231.23 g/mol and a CAS number of 1016783-13-3.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Cyclohexylethanethioamide is a regioselective borohydride reducing agent. It is used to reduce the aldehydes and ketones to the corresponding alcohols in high yields. 2-Cyclohexylethanethioamide can be used as an alternative to sodium borohydride or lithium aluminum hydride. The product can be used as an intermediate for other chemical compounds, such as pharmaceuticals, dyes, and perfumes.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,5-Dioxopyrrolidin-1-yl carbamate is a reactive, nucleophilic compound that is used to prepare amines. The pharmacokinetic properties of 2,5-dioxopyrrolidin-1-yl carbamate have been studied with the use of analytical methods such as basic proteins and activated carbon. This compound can be used as an inhibitor of enzymes in biological systems. It reacts with amino acids and other compounds containing nitrogen to form Schiff bases and imine derivatives. These reactions are reversible, so 2,5-dioxopyrrolidin-1-yl carbamate can be used to remove these groups from proteins. It has been shown that exposure to light will cause the decomposition of this compound.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(4-Nitro-pyrazol-1-yl)-ethanol is a cyclic anion that has been shown to be damaging to DNA. It has been studied by the kinetic methods of anion exchange chromatography and solvent extraction. 2-(4-Nitro-pyrazol-1-yl)-ethanol was found to be a weak base, with a pKb value of 10.2. The compound reacts with glutathione to form 2-(4-nitro-pyrazol-1-yl)-ethanesulfonic acid, which is in equilibrium with the corresponding alcohol. This reaction can be measured by monitoring the changes in absorbance at 260 nm and 280 nm. The nitro group on 2-(4-nitro-pyrazol-1-yl)-ethanol shifts the potentials of methylene blue and methyl green toward more positive values, making them more sensitive to this type of damage.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-(Diethylamino)butyric acid hydrochloride is a potent antimalarial drug that belongs to the group of benzothiopyrans. It has been shown to be an effective treatment for malaria. This compound is a phenolic compound, which contains a phenol group in its chemical structure. The esterification of 4-(diethylamino)butyric acid hydrochloride with water-soluble derivatives such as acetyl chloride or acetic anhydride yields water-soluble derivatives.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>N-Cyclopentylsulfamoyl chloride is a diuretic drug that is used in veterinary medicine. It has been shown to increase fertility in animals. N-Cyclopentylsulfamoyl chloride also has aliphatic, sulfamates, and sulfamoyl chloride properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(R)-1-(p-tolyl)ethan-1-ol is a chiral alcohol that can be synthesized through the reduction of p-chlorobenzaldehyde with sodium borohydride. It has been shown to have an inhibitory effect on bacterial growth, but not mammalian cells. The hydroxyl group on the (R)-1-(p-tolyl)ethan-1-ol molecule interacts with the cell membrane, which increases its permeability and thus allows for a greater substrate concentration. This reaction is stereoselective, so only one enantiomer will react with the enzyme. Preparative methods are employed to separate this compound from other enantiomers and purify it for use in biological experiments.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1-Piperidinyl)benzoic acid is an intramolecular, terminal oxidant. It activates a variety of bonds including C–H, C–X, N–H, and O–H bonds. This compound is also an efficient oxidant with high reactivity and selectivity. 2-(1-Piperidinyl)benzoic acid has been shown to be an aerobic oxidant that can activate a variety of bonds with high efficiency. In addition, this molecule has shown the ability to efficiently convert alcohols and esters into carbonyl compounds under dehydrogenative conditions.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-1-methyl-4-nitro-1H-pyrazole is a nucleophilic substitutive agent that is used in the synthesis of 7-deazapurines. 5-Chloro-1-methyl-4-nitro-1H-pyrazole is synthesized through a cross coupling reaction between an aldehyde and an azide. It has been shown to inhibit hepatitis C virus replication by interfering with the viral life cycle. It also inhibits the proliferation of cancer cells, which may be due to its ability to inhibit the production of certain proteins such as p21 and cyclin A.</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Pyrrolidin-1-yl)prop-2-en-1-one is a monomeric, hydrating, and inhibiting molecule. It has been shown to inhibit the homopolymerization of polydimethylsiloxane (PDMS) by competing with the PDMS for the active site on the enzyme DNA polymerase. 1-(Pyrrolidin-1-yl)prop-2-en-1-one also inhibits copolymerization of PDMS with methyl methacrylate (MMA). The inhibition constant for this molecule is 4.56 × 10 M, which corresponds to a half maximal inhibitory concentration of 2.14 × 10 M. The kinetic constants for 1-(pyrrolidin-1-yl)prop-2-en-1 one are k = 0.063/min and k = 0.0016/min, respectively.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Boc-2-phenylhydrazine is an organic compound that belongs to the group of azides. It is used as a reagent for the synthesis of biochemicals and pharmaceuticals. The yield of 1-Boc-2-phenylhydrazine can be increased by diluting it with tetrahydrofuran or diethylether, which are solvents that dissolve both hydrazines and amines. The reaction temperature must be controlled in order to avoid the formation of unsymmetrical azides, such as 2,4,6-trinitrophenylhydrazine. If the reaction temperature exceeds 60° C, then phenylhydrazine will be consumed and not produce 1-Boc-2-phenylhydrazine.</p>

<p>Versatile small molecule scaffold</p>