Building Blocks

<p>Applications 3,3'-Dithiobis[6-nitrobenzoic Acid is an membrane-impermeant thiol/disulfide exchange blocker. 3,3'-Dithiobis[6-nitrobenzoic Acid is also used to quantify the number or concentration of thiol groups in a sample.<br>References Calderon, M.N., et al.: Intervirol., 55, 451 (2012); Li, J.M., et al.: J. Material. Chem., 22, 12100 (2012);<br></p>

<p>Applications 2-Bromo-5-methylbenzoic acid<br></p>

<p>Stability Light Sensitive<br>Applications 4-Bromo-1,2-methylenedioxybenzene<br></p>

<p>Applications 2-Bromo-3-methylphenol is a reagent used in chemoselective and regioselective oxybromination of phenols with dioxygen<br>References Menini, L., et al.: Tetrahedron Lett., 48, 6401 (2007)<br></p>

<p>Applications 3-Bromo-2-methylphenol<br></p>

<p>Applications 3-Bromo-4-methylphenol is a component of the marine alga polysophornia Sphaerocarpa. It is also a useful raw material for organic synthesis and pharmaceuticals.<br>References Flodin, C., et al.: Phytochemistry, 53, 77 (2000); Munday, S. D., et al.: ChemCatChem, 9, 2512 (2017)<br></p>

<p>Applications 3-Bromo-5-methylphenol is a useful raw material for organic synthesis and pharmaceuticals.<br>References Golinski, M., et al.: Eicosanoids, 5, 87 (1992); Baldwin, J. E., et al.: Tetrahedron, 47, 5603 (1991); Ren, Z., et al.: Org. Lett., 18, 4958 (2016)<br></p>

<p>Applications 2-Bromo-4-nitrophenol<br></p>

<p>Applications 2-(1-(4-Bromophenyl)-1H-1,2,3-triazol-4-yl)propan-2-ol<br></p>

<p>Stability Light Sensitive<br>Applications Cis-1-Bromo-2-ethoxyethylene<br></p>

<p>Applications 2,6-Dimethylphenylboronic acid<br></p>

<p>Applications 2-Bromo-5-methoxybenzaldehyde is used in preparation of Benzimidazole Quinolines. Also, used in preparation of Cyclopentenes, Polycycles, Benzocarbocycles/N-Heterocycle derivatives.<br>References Zhou, B., et al.: Faming Zhuanli Shenqing, (2020); Wang, R., et al.: Chemistry - A European , 26, 1941-1946 (2020);<br></p>

<p>Applications Butoxy-d9-acetic Acid (CAS# 669720-55-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-BUTYNOIC ACID (cas# 2345-51-9) is a useful research chemical.<br></p>

<p>Applications 2-Bromo-3-methoxybenzoic acid (cas# 88377-29-1) is a useful research chemical.<br></p>

<p>Applications 4-(4-Bromo-3-formylphenoxy)benzonitrile (cas# 906673-54-9) is a useful research chemical.<br></p>

<p>Applications 1-Butylpyrrolidine (cas# 767-10-2) is a useful research chemical.<br></p>

<p>Applications 5-Bromo-2-(morpholino)benzonitrile (cas# 1105665-08-4) is a useful research chemical.<br></p>

<p>Applications 2-Bromo-6-morpholinobenzonitrile (cas# 1129540-65-3) is a useful research chemical.<br></p>

<p>Applications 1,4-Butane-d8-dithiol (CAS# 1219805-46-5) is a useful isotopically labeled research compound.<br></p>

<p>Applications 5-Bromo Pentane-1,1,1,2,2,3,3,4,4-d9 is a isotope labeled building block.<br></p>

<p>Applications tert-butyl 7-hydroxy-3,4-dihydroisoquinoline-2(1h)-carboxylate (cas# 188576-49-0) is a useful research chemical.<br></p>

<p>Applications tert-​Butyl 5-​(4,​4,​5,​5-​tetramethyl-​1,​3,​2-​dioxaborolan-​2-​yl)​isoindoline-​2-​carboxylate is a reactant in the synthesis of tyrosine kinase inhibitors in the treatment of proliferative diseases.<br>References WO Patent 2014089324 (2014); CN 104016979 (2014);<br></p>

<p>Applications 1-Bromo-2,3-dimethyl-2-butene is used as a reagent in the synthesis of (+)-virantmycin (CAS#: 104871-14-9).<br>References Morimoto, Y., et al.: Tetrahedron, 52, 10631 (1996)<br></p>

<p>Applications 2-Bromoethyl Acetate, is a versatile building block used in the synthesis of chemical compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (RS)-3,5-DHPG is a selective group I metabotropic glutamate receptor agonist which activates both mGluR1 and mGluR5. It has been shown that (RS)-3,5-DHPG can modulate Kir4.1 protein and mRNA in cultured rat retinal Müller cells.(RS)-3,5-DHPG acts as a potential target in treatment of parkinson's disease.<br>References (1) Gao, F., et al.: Neurosci Lett. 588, 12 (2015)<br></p>

<p>Applications 2-Butyn-1-ol has been used to inhibit corrosion of iron in acidic solution.<br>References Baddini, A. et al.: Electrochim. Acta., 53, 434 (2007); Babic-Samardzija, K. et al.: J. Mat. Chem., 15, 1908 (2005);<br></p>

<p>Applications Butyryl-d7-L-carnitine HCl is a useful isotopically labeled compound of (R)-Butyryl Carnitine Chloride (B802700)<br></p>

<p>Applications tert-Butyl 2,2,2-trichloroacetimidate is used in the conversion of alcohols and carboxylic acids to their respective ethers and esters.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wessel, H., et al.: J. Chem. Soc., Perkin Trans. 1, 2251 (1985); Armstrong, A., et al.: Tetrahedron Lett., 29, 2483 (1988)<br></p>

<p>Stability Air Sensitive<br>Applications 2-Bromo-4-methylaniline (cas# 583-68-6) is a useful research chemical.<br></p>

<p>Applications tert-Butyl Phenyl Carbonate is used in the synthesis of carbamate protected polyamines as well as in the preparation of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 modulating long chain fatty acid biosynthesis.<br>References Pittelkow, M. et al.: Synth., 15, 2195 (2002); Bengtsson, C. et al.: Bioorg. Med. Chem., 19, 3039 (2011);<br></p>

<p>Applications N-Butyl-3-hydroxybenzamide<br></p>

<p>Applications 2,6-Dinitrotoluene-alpha,alpha,alpha-d3 (CAS# 93951-90-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-(3-Butynyloxy)tetrahydro-2H-pyran is used as a reagent in the synthesis of Phomoidride D, a bridged, polycyclic, natural compound that has the ability to inhibit squalene synthase and can be used as an antihypercholesterolemic agent. 2-(3-Butynyloxy)tetrahydro-2H-pyran is also used as a reagent to prepare Rugulactone, a natural compound that is isolated from Cryptocarya rugulosa.<br>References Allais, F., et al.: Synthesis, 2010, 2787 (2010); Biller, S., et al.: Curr. Pharm. Des., 2, 1 (1996); Chen, C., et al.: J. Am. Chem. Soc., 122, 7424 (2000); Murphy, G., et al.: J. Org. Chem., 78, 477 (2013)<br></p>

<p>Stability Volatile<br>Applications 3-Butyn-1-ol is an unsaturated alcohol that is used as a reagent to synthesize Kainic acid (K135000), a neuroexcitatory and neurotoxic analogue of glutamate that is utilized as a means to selectively lesion neuronal cell bodies. 3-Butyn-1-ol is also an important intermediate to prepare a variety of natural products in food and cosmetic industries.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, J. &amp; Whiting, M.: J. Org. Chem., 68, 6160 (2003); Ben-Ari, Y., et al.: Brain Res., 165, 3362 (1979); Olney, J., et al.: Brain Res., 77, 507 (1974); Yu, X., et al.: Org. Prep. Proc. Int., 38, 467 (2006)<br></p>

<p>Applications 2,3-disubstituted benzaldehyde.<br></p>

<p>Applications trans-2-[3-(4-tert-Butylphenyl)-2-methyl-2-propenylidene]malononitrile (cas# 300364-84-5) is a useful research chemical.<br></p>

<p>Applications 4-tert-Butylaniline-d15 (CAS# 1219794-71-4) is a useful isotopically labeled research compound.<br></p>