Building Blocks

<p>Applications Ethylenediaminetetraacetic-d12 Acid (CAS# 203806-08-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Bis(6-methylheptyl) Phthalate-3,4,5,6-d4 (CAS# 2209087-06-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Inhibitor of enzyme. It is used for Phosphodiesterase Substrate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Preuss, C.V., Biochem. Pharmacol., 51, 1661 (1996),<br></p>

<p>Applications octahydro-1H-indole-2-carboxamide (cas# 1105694-34-5) is a useful research chemical.<br></p>

<p>Applications (5-Formylfuran-2-yl)boronic Acid is a reagent used in Suzuki cross-couplings with deactivated aryl bromides and activated aryl chlorides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Trinh, T. N., et al.: Org. Biomol. Chem., 12, 9562-9571 (2014);<br></p>

<p>Applications 2-(prop-2-ynyloxy)propanoic acid (cas# 134126-59-3) is a useful research chemical.<br></p>

<p>Applications 2-(prop-2-yn-1-yl)-1,2,3,4-tetrahydroisoquinoline-1,3-dione (cas# 410538-30-6) is a useful research chemical.<br></p>

<p>Applications N,N'-Bis(salicylidene)ethylenediamine is a common chelating ligand that is used in coordination chemistry. In particular it was used to form a new zinc(salen) nano complex which possess strong photoluminescence properties. Also used to form iron complexes which may possess anticancer properties.<br>References Mohammadikish, M., et al.: J. Cryst. Growth., 431, 39 (2015); Wani, W., et al.: New J. Chem., 40, 1063 (2016);<br></p>

<p>Applications methyl 2-hydroxy-4-methylpentanoate (cas# 40348-72-9) is a useful research chemical.<br></p>

<p>Applications 4,6,7-trichloroquinoline (cas# 855763-18-7) is a useful research chemical.<br></p>

<p>Applications BIX 01294 is a euchromatic histone-lysine N-methyltransferase 2 (EHMT2) inhibitor, induces autophagy and apoptosis in human neuroblastoma cells, specifically human bladder cancer cells.<br>References Cui, J. et al.: Cancer Cell Int., 15, 1 (2015); Shin, J. et al.: Biochem. Biophys. Res. Comm., 350, 428 (2015);<br></p>

<p>Applications 5-Formylfuran-2-boronic Acid Pinacol Ester could be useful for the diastereoselective synthesis of cyclic peptide macrocycles via Petasis borono-Mannich reaction<br>References Yamaguchi, A., et al.: Chem. Commun. (Cambridge, U. K.), 55, 10567 (2019)<br></p>

<p>Applications 4-(Methoxycarbonyl)phenylboronic Acid is used in the synthesis and evaluation of several organic compounds including that of 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate which is a potent inhibitor of intracellular NAAA activity. Also used in the design and synthesis of BMS-955176 which is a potent, orally active second generation HIV-1 maturation inhibitor.<br>References Nuzzi, A., et al.: Eur. J. Med. Chem., 111, 138 (2016); Rogueiro-Ren, A., et al.: ACS Med. Chem. Lett., 7, 568 (2016);<br></p>

<p>Applications 5-methoxy-1,3-dimethyl-1H-pyrazole (cas# 53091-80-8) is used as an active ingredient in making herbicides that control 90% of several weeds.<br>References Suzuki, F., et al.: Eur. Pat. Appl. 139pp. (1983)<br></p>

<p>Applications 3-Fluoro-6-bromopyridine is used in the synthesis of mGluR5 antagonist for the treatment of neuropathic pain.<br>References Son, M.H., et al.: Bioorg. Med. Chem. Lett., 23, 1472 (2013);<br></p>

<p>Applications 5-Formyl-8-hydroxycarbostyril is a metabolite of procaterol hydrochloride (Meptin), a β2-adrenergic agonist used in the treatment of asthma.<br>References Kobayashi, H. et al.: Int. J. Clin. Pharm. Ther., 48, 744 (2010);<br></p>

<p>Applications (S)-(-)-1-Phenylpropylamine is used in the synthesis of a new series of L-Aspartyl-D-amino amide sweeteners. They contain a sweetness potency 2000 times that of a 10% sucrose solution. Also, a molecular determinant of substrate specificity for transaminases, owing to its chiral carbon.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sweeny, J. et al.: J. Agri. Food Chem., 43, 1969 (1995);<br></p>

<p>Applications 1-(1-phenylcyclobutanecarbonyl)piperidine-4-carboxylic acid (cas# 1099048-69-7) is a useful research chemical.<br></p>

<p>Applications An intermediate for the synthesis of polymers used for in vivo delivery polyconjugate systems.<br>References Antonopoulou, G., et al.: Bioorg. Med. Chem., 16, 10257 (2008),<br></p>

<p>Applications Iodoethane-1-d1 (CAS# 3652-81-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Boc-4-(aminomethyl)piperidine is a protected 4-substituted piperidinecarboxylate used in the preparation of orally active platelet-activating factor antagonists as well as other biologically active compounds.<br>References Carceller, E. et al.: J. Med. Chem., 39, 487 (1996);<br></p>

<p>Applications 5-Methoxy-1-naphthalenol (cas# 3588-80-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Nε-Boc-D-lysine is an N-Boc-protected form of L-Lysine (L468895). L-Lysine is an essential amino acid for humans, with a suggested intake of 5-8 grams per day. L-Lysine can be found in a variety of food, such as eggs and quinoa, but is also mass produced by microbial fermentation. L-Lysine is also used as therapy to treat recurrent herpes simplex infections.<br>References Anastassiadis, S.: Biotechnology, 1, 11 (2007); Civitelli, R., et al.: Nutrition, 8, 400 (1991); Griffith, R., et al.: Dermatology, 175, 183 (1987)<br></p>

<p>Applications L-Lysine-4,4,5,5-d4-bis-N-t-BOC (CAS# 1314753-85-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Furan-2-boronic acid<br></p>

<p>Applications N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE (cas# 55750-63-5) is a useful research chemical.<br></p>

<p>Applications A chemical model used for the study and analysis of human buccal absorption of pharmaceuticals.A fundamental starting material for organic compound synthesis.<br>References Vora, K., et al.: J. Pharm. Sci., 61, 1785 (1972),<br></p>

<p>Applications Furfuryl-d5-amine (CAS# 1219799-26-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4- Bromobenzonitrile is classified as organic nitriles, which are commonly use solvents and are reacted further for various applications such as manufacture of polymers and intermediates for pharmaceuticals and other organic chemicals,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, C.F., et al.: Tetrahedron Letters. 53, 5389 (2012).<br></p>

<p>Stability Air Sensitive<br>Applications Furfuryl Mercaptam is a volatile flavor component of corn tortilla chips.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Guadagni, D., et al.: J. Sci. Food Agric., 23, 1435 (1972), Kerler, J., et al.: J. Food Sci., 61, 1271 (1996), Buttery, R., et al.: J. Agric. Food Chem., 45, 837 (1997),<br></p>

<p>Applications α-D-Glucopyranuronic Acid Methyl Ester 2,3,4-Tribenzoate 1-Methanesulfonate is a reactant in organic synthesis. It is used in the preparation of novel quaternary glucuronyl reagent for preparation of tertiary amines.<br>References Araya, I. &amp; Akita, H.: Heterocycles., 75, 1213 (2008)<br></p>

<p>Applications 4-Bromobenzaldehyde is part of a group of benzaldehydes that have in vivo antibacterial activity against Mycobacterium tuburculosis. 4-Bromobenzaldehyde is also used as a reagent in the synthesis of 4-Bromobenzaldehyde semicarbazone, a trial compound of a novel class of anticonvulsants.<br>References Dimmock, J. &amp; Baker, G.: Epilepsia, 35, 648 (1994); Ferreira, M., et al.: Lett. Drug Des. Discov., 7, 754 (2010)<br></p>