Building Blocks

<p>Versatile small molecule scaffold</p>

3-Bromobenzothiophene-2-carboxylic acid is an organic compound that is used in the synthesis of pharmaceuticals, including anticancer agents. It inhibits the growth of cancer cells by binding to a specific site on their DNA and preventing the formation of terminal alkynes. 3-Bromobenzothiophene-2-carboxylic acid has been shown to be a potent inhibitor of lactamase, which is an enzyme that breaks down lactams and other esters. This effect leads to decreased cell proliferation in some cancer cells. 3-Bromobenzothiophene-2-carboxylic acid also has a fluorescent property, which can be used for research purposes.

<p>Versatile small molecule scaffold</p>

<p>3-Formylfuran-2-carboxylic acid is a furanic sugar derivative that is used as a sweetener. It can be obtained by the reaction of glycerol with formaldehyde and catalytic acid. 3-Formylfuran-2-carboxylic acid has a particle size of less than 2 microns, which means it can be used in chewing gum and other food products. This product has been shown to have antioxidant activity due to its ability to scavenge free radicals and inhibit oxidation, making it suitable for use as a preservative.</p>

Ethyl 1,3-benzothiazol-2-ylacetate is a coumarin derivative that has been shown to be active against tuberculosis. It inhibits bacterial growth by binding to the gyrase enzyme and preventing the formation of a new DNA strand. The synthesis of ethyl 1,3-benzothiazol-2-ylacetate starts with the condensation of 2 molecules of acetoacetic ester in the presence of an acid catalyst. This reaction takes place in vivo in animal tissues and is catalyzed by enzymes such as gyrase or topoisomerase IV. The reaction time for this synthesis is typically 3 hours. Ethyl 1,3-benzothiazol-2-ylacetate emits fluorescent emissions at a wavelength of 330 nanometers.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

5-Methoxy-2-thiophenecarboxylic acid is an aldehyde that is synthesized by the reaction of lithium, phosphoryl chloride and thiophene. The azomethine group in this compound can be converted to the corresponding phosphoryl chloride and sulfides. 5-Methoxy-2-thiophenecarboxylic acid is used as an intermediate for manufacturing dyes and pharmaceuticals, such as analgesics and antibiotics.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

(2S)-2-{[(2S)-5-Oxopyrrolidin-2-yl]formamido}pentanedioic acid is an optically active glutamic acid amide, which is a natural product. It has a bitter taste and may be found in soybeans and zinc salts. The salt form of this compound is used as a mouthwash to reduce the sensation of bitterness. This compound has been reported to have anti-inflammatory activities and has been shown to inhibit the growth of Aspergillus flavus and other fungi.

Versatile small molecule scaffold

Fa-Gly-OH is a molecule that is used to study the kinetics of drug metabolism and the metabolism of drugs. It can be synthesized from glycerol and furfural, which are both readily available chemicals. Fa-Gly-OH has been shown to have a magnetic resonance profile that is similar to that of other fatty acids. The metabolic profile of this molecule was determined in groups of mice, with doses ranging from 10 mg/kg to 500 mg/kg. Fa-Gly-OH was found to be metabolized in the liver, with no detectable levels in the urine or faeces. Fa-Gly-OH is eventually converted into conjugates, such as methylglyoxal, which are excreted in the urine and faeces.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(1,2-Benzothiazol-3-yl)acetic acid is a plant hormone that is found in the indole-3-acetic acid family of plant hormones. It is one of the auxins and it has been shown to promote germination and root growth. Auxins have also been shown to be involved in the development of vascular tissue and other aspects of plant growth. 2-(1,2-Benzothiazol-3-yl)acetic acid has been isolated from Pisum sativum L., Lycopersicon esculentum, and Esculentum.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Ethyl 2-methyl-3-oxohexanoate is an ester with a chemical formula of C8H14O2. It is an acyclic compound and a member of the ethers family. It has the molecular weight of 132.17 g/mol and a density of 0.965 g/mL at 25°C. The melting point for this compound is -78°C and it has a boiling point of 164°F (73°C). Ethyl 2-methyl-3-oxohexanoate has been found to have high levels in Delphinium species, which are plants that contain alkaloids such as methyllycaconitine, which are analogues to the more well known morphine. This ester can be synthesized from the reaction between ethyl acetate and benzaldehyde.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine is a functional molecule that belongs to the pyridazinone class. It has been shown to be an ionic liquid with a dihedral angle of tetragonally and a water molecule as a hydrogen bond donor. 3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine has been used in diagnostic techniques such as potentiodynamic polarization and electrochemical impedance spectroscopy.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>1-Ethyl-3-(2-hydroxyethyl)urea is a chemical compound that is an equimolar mixture of two isomers, 1-ethyl-3-(2-hydroxyethyl)urea and 3-(2-hydroxyethyl)-1-methylurea. It has been shown to induce death in tumor cells, but not in normal cells. The molecular targets for this compound are the mitochondria and the DNA, which are essential for cell growth and division. This drug also has carcinogenic properties, meaning that it can cause cancer. In animal studies, 1-ethyl-3-(2-hydroxyethyl)urea has been shown to cause thyroid tumors and astrocytomas (brain tumors). In addition, this drug causes hepatocellular carcinoma in rats and gliomas (brain tumors) in animals.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>(2R)-1-Phenylbutan-2-ol is an isomer of 1-phenyl-2-propanol. It has been shown to have potent antituberculosis activity, with a high yield and good stereochemical purity. In the tautomeric form, it inhibits the growth of Mycobacterium tuberculosis by inhibiting protein synthesis.</p>

<p>5-acetyltetrahydrofuran-2-one (5AHT) is a natural compound that has been shown to have antimicrobial and antioxidant properties. It is a biomimetic of glutamic acid, which has been shown to have biological properties such as anti-inflammatory, antipyretic, analgesic and antidiabetic effects. 5AHT has been used in the preparation of diethyl succinate, an organic acid that has potential applications in food chemistry. The chemical structure of 5AHT consists of two carbonyl groups bonded to a furan ring with two hydroxyl groups on the other side. The resonance mass spectrum of 5AHT consists of an acetaldehyde peak at 20 ppm and a peak at 77 ppm for the methylene protons. The 5AHT molecule can exist in two isomers: <br>5AHT (E)-OCH3 or 5AHT (Z)-OCH3</p>

N,N-Dimethyl-2-(N-methylacetamido)acetamide is an amide compound that is used as a solvent. It has a molecular weight of 143.16 and boiling point of 209 °C. This compound has been experimentally shown to have n-terminal kinetic stabilization and orbital interaction with the acceptor molecule. N,N-Dimethyl-2-(N-methylacetamido)acetamide is also underivatized, meaning it does not contain any functional groups for further chemical reactions. The conformational stability of this compound is dependent on the carbonyl oxygen at the c-terminus in addition to its electron affinities.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromobenzohydrazide is an antibacterial agent that has been shown to have good intestinal absorption. It is a crystalline solid, which is soluble in organic solvents and insoluble in water. The molecular weight of 2-bromobenzohydrazide is 238.24 g/mol, with a melting point of 108°C. 2-Bromobenzohydrazide has been shown to be active against Streptococcus aureus, Mycobacterium tuberculosis, and other bacterial strains. The mechanism of action for 2-bromobenzohydrazide involves the formation of a covalent bond with amino groups on the cell wall or membrane surface of bacteria, which results in damage to the bacterial cell membrane. This inhibits the synthesis of proteins and nucleic acids as well as causes death by inhibiting cellular respiration.</p>

<p>Versatile small molecule scaffold</p>

<p>5-Methylthiophene-3-carbaldehyde is a ketone that is the product of the reaction between 3,4-dimethoxybenzaldehyde and acetic acid. It is a colorless liquid with a sweet odor. 5-Methylthiophene-3-carbaldehyde has been used as a reagent for the synthesis of benzylic alcohols and as a starting material for other organic compounds.</p>

4-Bromo-5-methylthiophene-2-carboxaldehyde (BMTCA) is a chemical that is synthesised by the reaction of ethylene with irradiation. It has been shown to have photochromic properties and can be used as an alternative to 4,4'-dithiodimorpholine (DIMO). BMTCA is hydrophilic and can be used for the synthesis of homologues. It also undergoes an x-ray structure analysis, yielding information on its physical properties and how it reacts with other chemicals. The process of digitalization allows for the conversion of analog signals into digital signals. This process uses a shift register, which is a device that stores data in sequential memory cells and outputs them on a single line. The diels–alder reaction is a chemical reaction between two unsaturated compounds to form 1,3-dienes or 1,4-diynes. This reaction is highly useful because it can

6-Hydroxy-4,4-dimethyl-3,4-dihydro-2H-1-benzopyran-2-one (6HDM) is a lipid lowering agent that has been shown to have antibacterial activity. It is a synthetic drug with an optical imaging technique that has been shown to inhibit the growth of cancer cells in vitro. 6HDM also inhibits UVB induced skin cancer by decreasing the expression of p65. 6HDM inhibits the biosynthesis of nucleic acids and protein synthesis in cancer cells by acting as a competitive inhibitor for intramolecular hydrogen transfer. This leads to cell death through apoptosis and necrosis.