Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Chloro-2-phenylethylbenzene is an organic compound that is used in the synthesis of other compounds. It is produced by reacting a chlorinated benzene with an alkali, such as sodium hydroxide, potassium hydroxide, or lithium hydroxide. The reaction produces a mixture of 2-chloro-2-phenylethylbenzene and phenylhydroxyethane. This compound can be converted to 2-chloro-2-(piperidin-1-yl)ethanol by refluxing it with morpholine in methanol and then adding amides such as piperidine or pyrrolidine. The resulting product can be alkylated with carbon tetrachloride to produce 2-chloro-2-(4'-methylphenoxy)ethanol. This compound can also be reduced to give 2-(4'-methylphenoxy)ethanol by heating it with sodium bor

Versatile small molecule scaffold

1,6-Hexylenediphosphonic Acid (HEDP) is an organic compound that belongs to the class of phosphonates. It has been used as a corrosion inhibitor in industrial water systems and as a chelating agent for metal ions such as zinc sulfate. HEDP is believed to be formed by the trimerization of ethylene and vinyl ether under high temperatures. The nature of HEDP's structure has been studied by X-ray diffraction and coordination chemistry. This compound shows strong interaction with metals and ligands, so it is often used in structural studies at various temperatures.

Versatile small molecule scaffold

Versatile small molecule scaffold

Spiro[4.5]decan-1-one is a synthetic drug that has been shown to have affinity for cardiac, neuropathic, and depression receptors. It also has moderate affinity for the acetylcholine receptor in the brain and acts as a stabilizer. Spiro[4.5]decan-1-one may be useful in treating Alzheimer's disease, Parkinson's disease, chronic pain, and psychosis because it can stabilize neuronal membranes and prevent cell damage caused by free radicals. This compound may also be used to treat cognitive disorders such as memory loss and attention deficit hyperactivity disorder (ADHD).
Spiro[4.5]decan-1-one is a nitrogenous compound that has been shown to have anticholinergic effects on cognition in rats. It is thought that its effects are mediated through its ability to block the action of acetylcholinesterase enzymes that break down acetylcholine at synapses in the brain.

3,5-Dimethylpicolinic Acid is a synthetic compound that has shown antiulcer activity. This compound has been shown to inhibit the production of sulfate and nitrite, which are involved in the synthesis of gastric acid. 3,5-Dimethylpicolinic Acid also inhibits the release of hydrogen peroxide from cells and increases the synthesis of cGMP by inhibiting phosphodiesterase type IV. It may be used as an alternative to sodium nitrite for meat preservation.

5H,7H-Furo[3,4-b]pyridin-7-one is a compound that can be synthesized from anhydride and halogen. It can be prepared from cycloalkyl and chlorinating alkoxy by formulas. The high yield of this compd, which is hydrolyzed to the chloride, can be selectively chlorinated with dicarboxylic alkali. 5H,7H-Furo[3,4-b]pyridin-7-one is used as a precursor for synthesis of aralkyl.

Versatile small molecule scaffold

The compound furo[3,4-c]pyridin-1(3H)-one is a nature-derived compound. It is an analgesic that has been shown to be biodegradable and non-toxic. The compound interacts with the benzodiazepine binding site of the GABA receptor and has a spectrum of activity that includes antibacterial, antifungal, antiviral, and antiprotozoal properties. This compound can also be synthesized in a number of ways that produce different isomers. These structural isomers are distinguished by their ability to bind to benzodiazepine receptors.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Valproic acid is an organic compound with the formula (CHCO)COOH. It is a white crystalline solid that is insoluble in water and most organic solvents. Valproic acid has been used in medicine as an anticonvulsant, mood stabilizer, and bipolar disorder medication. Valproic acid is also used to treat hyperammonemia, although this use is limited by its side effects. To produce valproate semisodium, sodium carbonate and valproic acid are combined at high temperatures to form sodium valproate and carbon dioxide gas. The molecular weight of valproic acid ranges from 100-400 Da. The low molecular weight of this drug makes it suitable for oral absorption and rapid distribution throughout the body. This assay uses a chromatographic method for detection with fluorescence detection at excitation/emission wavelengths of 280/365 nm. The results show that 6-Amino-2-propylhexano

o-Tolylbiguanide hydrochloride is a copper-containing antimicrobial agent that has been synthesised and used to treat Gram-negative bacteria. It is an anion, which means it can be reduced by agents such as formaldehyde and chloride. o-Tolylbiguanide hydrochloride binds to the anionic groups of the bacterial cell wall, which are found in proteins and lipids. This binding prevents the formation of a covalent bond between the copper ion and the bacterial cell wall, preventing further growth. The elimination of this compound in vivo is thought to be due to its organic ligands.