Building Blocks

<p>Pyrrole-2-carboxylic acid is a polycyclic aromatic compound that can be found in coal tar. It has been shown to have anti-inflammatory, antiallergic, and antifungal properties. Pyrrole-2-carboxylic acid is produced by the human body as an intermediate in the metabolism of tryptophan. This compound can also be synthesized and used to treat chronic bronchitis, which is caused by excessive mucus production and inflammation of the airways. The reaction mechanism for pyrrole-2-carboxylic acid is similar to that of other drugs that are used in respiratory therapy, such as aminophylline or acetylcysteine.</p>

<p>2-Pyridineboronic acid is a chemical compound that belongs to the group of quinoline derivatives. It is used in pharmaceutical preparations, including as an intermediate for the synthesis of other compounds. 2-Pyridineboronic acid has been shown to have antiproliferative effects on cancer cells and has been found to be active against nicotinic acetylcholine receptors (NAR). The compound also inhibits lipid kinase activity, which is involved in the production of phosphatidylcholine and phosphatidylethanolamine from phosphatidylserine. 2-Pyridineboronic acid can react with hydrochloric acid and electrochemical impedance spectroscopy to produce a solution that has a detection time of about 10 minutes.</p>

<p>1H,1H,7H-Dodecafluoroheptanol is a perfluorinated compound. It has been shown to be an efficient scavenger of reactive oxygen species (ROS) and to have a protective effect on collagen. The reaction mechanism of 1H,1H,7H-dodecafluoroheptanol is not fully understood. However, it has been shown that the chloride ion plays a key role in the formation of this product from 1H,1H,7F-dodecafluoroheptane. The reaction vessel used in this synthesis is critical because it must be anhydrous to prevent the formation of 1HF3OCl. Magnetic resonance spectroscopy has been used to study the chemical structures of this compound.</p>

<p>2,3-Pyridinedicarboxylic acid dimethylester (PDDE) is a methylated derivative of 3-nitrophthalic anhydride. It has been shown to be a stereoselective receptor blocker that binds to the glutamate site of the N-methyl-D-aspartate receptor. PDDE has also been shown to have high affinity for the cerebral cortex and is able to penetrate the blood brain barrier. PDDE blocks the NMDA receptor by binding to it and preventing ion flow, which leads to inhibition of neurotransmitter release. This drug is used as an injectable methyl derivative with a molecule weight of 217. The ionization detector can detect PDDE in tetrahydrofuran at concentrations of 1,000 ng/mL or less.</p>

<p>Fmoc-Lys-OH·HCl is an acidic pyrylium that has been shown to be a potent inhibitor of tumor vasculature. It binds to the human serum albumin and inhibits the binding of ligands to the receptor tyrosine kinases, which are involved in brain tumor proliferation. Fmoc-Lys-OH·HCl has also been shown to inhibit the growth of cancer cells by binding to cell membrane receptors and inhibiting protein synthesis. This compound is also isomeric, meaning it can exist in different forms with different properties.</p>

<p>Fmoc-a-Me-Lys(Boc)-OH is a versatile building block that can be used in the synthesis of complex compounds. It is a reagent and speciality chemical, which are substances used in research laboratories. Fmoc-a-Me-Lys(Boc)-OH has been used as an intermediate in the synthesis of drugs such as antihypertensive agents, anticonvulsants, and antibiotics. It has also been used as a reaction component in organic syntheses to produce peptides, polymers, and other compounds with biologically active properties.</p>

<p>Fmoc-b-Ala-Ala-Pro-OH is a reaction component that can be used in the synthesis of peptides and other compounds. It is a building block for the preparation of complex compounds, such as small molecules, polymers and natural products. Fmoc-b-Ala-Ala-Pro-OH has been shown to be useful in the synthesis of various types of reagents, including antibiotics and pharmaceuticals. This chemical has been reported as a useful scaffold for the preparation of high quality research chemicals. Fmoc-b-Ala-Ala-Pro is also an intermediate in the synthesis of speciality chemicals and fine chemicals.</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 4-bromoacetoacetate is a chemical compound that is used in the synthesis of quinoline derivatives. It also has antiinflammatory properties and can be used to treat inflammatory diseases such as arthritis. The thermal expansion of this compound is greater than that of water, which can be useful in treating respiratory problems by providing increased oxygen transport. Ethyl 4-bromoacetoacetate is a reactive chemical that reacts with hydrochloric acid to produce hydrogen gas and ethyl bromide gas. It also undergoes nucleophilic substitutions at the carbon atom adjacent to the acetoacetate group. This reaction solution can be analyzed using magnetic resonance spectroscopy, which produces data on the sequences of this compound's atoms and its antiinflammatory activity.</p>

<p>Versatile small molecule scaffold</p>

<p>5-bromo-3,3-dimethyl-2,3-dihydro-1H-indole is an activator that is used in palladium catalyzed reactions to form a phosphine ligand. 5-bromo-3,3-dimethyl-2,3-dihydro-1H-indole is also used as a vasotropic agent and reagent for organic synthesis. It is used to synthesize ethylesters and salts of 5-(5'-bromo)-2,2'-dihydroquinoline carboxylic acid. This compound can be hydrolyzed with alkaline solution to produce the corresponding amine.</p>

<p>Ethyl cyclopropaneacetate is an organic compound that belongs to the class of aminophenyl ethyl esters. It has been shown to inhibit neutrophil migration and angiotensin II-induced vasoconstriction in cerebral arteries, suggesting that it may have a role in the treatment of chronic bronchitis. Ethyl cyclopropaneacetate has also been shown to have antimycotic activity against Candida albicans and Aspergillus niger, as well as cancer-fighting effects. This compound is synthesized by reacting triethyl orthoformate with adenosine under mild conditions. The reaction system is high yielding and can be used for the synthesis of other drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>3,3,5-Trimethylcyclohexanone is an intermediate in the synthesis of polymers and polyesters. This compound is a reactive hydrogenation product which can be used to produce polymers with desired properties. The unsaturated side chain of 3,3,5-trimethylcyclohexanone reacts with borohydride to form a ketal. After being converted to the corresponding acid chloride, the 3,3,5-trimethylcyclohexanone can be used for the synthesis of polyesters. This compound has also been shown to be an effective catalyst for producing β-unsaturated ketones from aldehydes and dienes.</p>

<p>Versatile small molecule scaffold</p>

<p>3,4,5-Trimethoxybenzoyl Chloride is a reactive, active chemical that is used in the synthesis of cytotoxic amides. It is prepared by reacting 3,4,5-trimethoxybenzoic acid with an amine or ammonia in the presence of a base. The reaction yields an amide substituted at the 3- and 4-positions with trimethoxyphenyl groups.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Iodo-1-methyl-1H-pyrazole-5-carbonitrile is a tetrazole molecule that has been shown to have potent and selective inhibitory activity against human PCSK9. This compound binds to the catalytic site of PCSK9 and prevents the formation of an active enzyme, therefore inhibiting the production of LDL cholesterol. 4-Iodo-1-methyl-1H-pyrazole-5-carbonitrile is a prodrug that is metabolized by acetaldehyde dehydrogenase to form an active inhibitor. The reaction proceeds in a chiral and enantioselective manner, which allows for the synthesis of racemic mixtures of this drug.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Acetylbenzoic acid is a functional molecule that contains an acetyl group. It can form hydrogen bonds with other molecules and has been shown to induce apoptosis in cells. The reaction products of 2-acetylbenzoic acid are malonic acid, acetylsalicylic acid, and 2-benzoylbenzoic acid. These three compounds are made by the addition of hydrogen or hydroxide to the molecule 2-acetylbenzoic acid. The molecule has two functional groups: a carbonyl group and an acetyl group. The chemical structure of this molecule can be seen in the figure below.<br>2-Acetylbenzoic Acid</p>

<p>Versatile small molecule scaffold</p>

<p>Bromo-PEG3-azide is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Bromo-PEG3-azide is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

<p>2-Bromo-3-hydroxy-benzaldehyde is a nitrate that has been shown to have anti-cancer properties. It inhibits the growth of cancer cells by binding to bromodomains in their DNA, thereby preventing transcription and replication. 2-Bromo-3-hydroxy-benzaldehyde also inhibits the production of nitric oxide, which may lead to an inhibitory effect on tumour angiogenesis. The stereoisomers of this compound are used as precursors for the synthesis of ammonium nitrate, which is used as a fertilizer and explosive. 2-Bromo-3-hydroxy-benzaldehyde is also used in organic synthesis as a precursor for acetylation or halide reactions with palladium complexes or halides.</p>

<p>2-Bromocyclopentanone is an organic molecule that is used in the synthesis of epoxides. It is also a potential precursor for the synthesis of polymers, dyes, and pharmaceuticals. 2-Bromocyclopentanone has been shown to undergo photolysis when irradiated with ultraviolet light or through chemical reaction with acetonitrile. This product has two conformers with different rotational barriers and corresponding spectral properties. The two conformers can be distinguished by their ultraviolet spectra. The synthetic methods for 2-bromocyclopentanone involve halogenation followed by hydrolysis to yield bromoacetic acid, which is then converted to the desired product by acylation or alkylation.</p>

<p>Versatile small molecule scaffold</p>

<p>3-Ethyl-4-methylpyrrole-2,5-dione is a chlorophyll analog. It has been found to be an electron donor in photosystem II of the chlorobium reaction center. The compound was prepared by evaporation of a solution of chlorobenzene and ethyl acetoacetate in carbon tetrachloride with the aid of a vacuum pump. 3-Ethyl-4-methylpyrrole-2,5-dione has also been used as a reagent for the preparation of phycocyanin from Spirulina platensis, which is an important component of blue algae. The compound reacts with phenoxy and furyl groups under acidic conditions to produce carboxylate and calcium carbonate, respectively. Oxidation products are formed in reactions with ethyl group and other organic compounds under alkaline conditions.</p>

<p>1-Adamantane carboxylic acid is a hydrophobic molecule that can form a complex with metal hydroxides. It is used in the process optimization of the synthesis of sodium salts. 1-Adamantane carboxylic acid binds to metals, such as magnesium and calcium, in a coordination geometry that is similar to that observed for water molecules. The complexation of 1-Adamantane carboxylic acid with metal ions results in an acidic environment, which is important for bowel disease. This acid complex also has anti-inflammatory properties. The hydroxyl group on the 1-adamantane carboxylic acid reacts with oxygen to form an alcohol group and this reaction mechanism may be involved in physiological functions.</p>

<p>2-Amino-4-bromopyridine is a potent, selective antagonist of the nicotinic acetylcholine receptor (nAChR) that has been shown to inhibit the proliferation of cancer cells in vitro. 2-Amino-4-bromopyridine binds to the nAChR and stabilizes it by binding to an allosteric site on the receptor. 2-Amino-4-bromopyridine is synthesized from 4,5-dibromobenzene and 2,6-diaminopyridine in two steps with a yield of 47%. The synthesis of 2-amino-4-bromopyridine proceeds via reaction mechanism involving electrophilic substitution at the bromine atom followed by nucleophilic addition at the nitrogen atom.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Acetylimidazole is a histidine analogue that has been shown to have anticancer activity in breast cancer cells. It can react with amines and form imidazoles. The hydroxyl group on the 4-position of the imidazole ring is able to undergo dehydration, which leads to the formation of a chloride ion. This reaction mechanism is reversible and can be used in organic synthesis. 4-Acetylimidazole can also act as an h2 receptor antagonist, although it does not bind to the zwitterionic site of the h2 receptor. NMR spectra show that 4-acetylimidazole exists as a zwitterion in water solution, but becomes a monovalent ion when dissolved in an organic solvent such as methanol or acetone. 4-Acetylimidazole is chemically stable and does not react with poloxamer.</p>

<p>1,4-Benzenedicarboxylic acid, monoethyl ester (1,4-BDE) is a monomer that is used in the manufacture of polycarbonates and other plastics. 1,4-BDE is also used as a solvent for xylene and butanol. It has been shown to be useful in the production of polyester fibers. The monomer can be synthesized by reacting ethylene with terephthalic acid or dimethyl terephthalate (DMT). This reaction produces 1,4-BDE and methanol as byproducts. The process is carried out at temperatures of 250 °C to 300 °C and under atmospheric pressure. The purified product can be isolated using distillation or extraction with organic solvents such as benzene or butanol. The reaction can be carried out in the presence of ruthenium, which acts as a catalyst.</p>

<p>4-tert-Butoxybenzaldehyde is a colorless liquid that has a viscosity of 0.3 mm2/s at 25 °C. It can be synthesized by reacting pyridine with hydrochloric acid in the presence of a Grignard reagent. 4-tert-Butoxybenzaldehyde reacts with phenolic antioxidants to form an ester, which can be used as an industrial solvent. The crystal x-ray diffraction pattern of 4-tert-Butoxybenzaldehyde exhibits peaks at 2θ = 8.0, 11.5, and 18.5° corresponding to the (100), (200), and (220) planes, respectively. This chemical can also undergo reactions that lead to termination or transfer reactions, including diethyl ketomalonate formation with diethyl malonate in the presence of water as a solvent and potassium hydroxide as a catalyst for transfer reactions.END&gt;</p>

<p>Versatile small molecule scaffold</p>

<p>5-Chloro-2-methoxycarbonyl pyrazine is a linker that is used to connect two pharmacophores. β-Lactamase, which is an enzyme that degrades β-lactams antibiotics, was inhibited by 5-chloro-2-methoxycarbonyl pyrazine in vitro and in vivo. The inhibitory potency of 5-chloro-2-methoxycarbonyl pyrazine was increased when it was combined with other molecules. This molecule has shown antibacterial activity against Enterobacter cloacae, methicillin resistant Staphylococcus aureus (MRSA), and Mycobacterium tuberculosis.</p>

<p>Pentanimidamide hydrochloride is a drug that belongs to the group of aromatic hydrocarbon drugs. It is a potent antihypertensive agent with a rapid onset and long duration of action. Pentanimidamide hydrochloride has been shown to inhibit the production of reactive oxygen species, which are generated by the respiratory chain in mitochondria, and to prevent the formation of pyrazinoic acid, an inhibitor of blood vessel relaxation. This drug also has been shown to reduce blood pressure in animal models by binding to specific receptors on cells in the cardiovascular system. The active form is bound to plasma proteins such as albumin and alpha-1-acid glycoprotein, which are found in high concentrations in erythrocytes. Pentanimidamide hydrochloride also binds to alkynyl groups and phenyl groups, which may be due to its ability to form covalent bonds with these functional groups.</p>

<p>Corey lactone 4-phenylbenzoate is an efficient, large-scale preparation of (-)-Corey lactone. It is synthesized in two steps from 4-phenylbenzoic acid and ethyl acetoacetate. Corey lactone 4-phenylbenzoate has been used for the synthesis of a variety of natural products. This compound is also a precursor to the synthesis of other compounds, such as 3-amino-4-(2'-hydroxyethoxy)benzaldehyde.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 2-Bromo-1-(4-chloro-3-fluorophenyl)ethanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (3S)-3- [4- [(2-Chlorophenyl) methyl] phenoxy] tetrahydrofuran including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Chlorpheniramine N-oxide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 6-(Chloromethyl)pteridine-2,4-diamine monohydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>