Building Blocks

Versatile small molecule scaffold

2-methyl-3,5-dinitrothiophene is an organic solvent with a nonlinear optical response. It has been used as a monomer for the preparation of polymers. 2-Methyl-3,5-dinitrothiophene has shown thermal stability and hydroxy groups that can be used to solvate other molecules. This compound is also soluble in organic solvents such as acetone and chloroform. The chromophore present in 2-methyl-3,5-dinitrothiophene gives it a yellow color at low concentrations and a reddish color at high concentrations.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Methoxy-3-phenylpropanoic acid is an ester with a carboxylic acid group at its end. It is a chiral molecule that has two enantiomers, which are mirror images of each other. The stereochemical conformations of these molecules can be determined by the weighting of their conformational energies. This compound is used in the synthesis of various pharmaceuticals and pesticides, such as carbamates and herbicides. The nmr spectroscopic data for this compound show that it has two conformers, A and B, which have different chemical shifts in their nmr spectra. The experimental data show that the equilibrium between these two conformers is weighted heavily to conformer A because it has a lower energy barrier than conformer B.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Benzylsulfanylbenzaldehyde is a benzyl derivative that has been studied for its optical properties and electronic structures. The sulfur atom in this molecule is replaced with an electron-donating group, which gives the molecule a positive charge. This change also makes the substituent more polar and thus increases its ability to interact with other molecules. Substituents are groups attached to benzene rings in order to modify their chemical or physical properties. Chromophores are groups of atoms that absorb light and can be used to identify substances by their color. Electron withdrawing groups cause the dipole moment of the molecule to increase, while electron donating groups have the opposite effect on the dipole moment.</p>

<p>2-Chloro-6-(chloromethyl)pyridine (2C6CP) is a chloride precursor that can be used for the synthesis of metal chlorides, such as copper chlorides. 2C6CP is synthesized by reacting thionyl chloride with the substituted pyridine under anhydrous conditions at -78°C. The resultant 2C6CP is then hydrolyzed to produce the desired chloride.<br>2C6CP has been shown to act as a ligand in coordination chemistry. It was first synthesized by reacting 3-chloropyridine with thionyl chloride and then hydrolyzing it to 2-chloropyridine. This method was later modified to use 4-chlorobenzoyl chloride instead of 3-chloropyridine, producing 2,4-dichloropyridine.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>1-Ethynyl-2-(methylsulfanyl)benzene is a potent antioxidant. It has been shown to have antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal activity against both mold and yeast. 1-Ethynyl-2-(methylsulfanyl)benzene has been shown to inhibit the growth of S. aureus and E. coli in vitro, having an IC50 of less than 0.1 μg/mL. This compound also inhibits the growth of Bacillus subtilis and B. cereus, with IC50 values of 0.5 and 0.06 μg/mL respectively, but is not active against Escherichia coli or Pseudomonas aeruginosa at concentrations up to 200 μg/mL.</p>