Alcohols

Applications 2-Butoxyethanol is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.
References Sun, Y., et al.: Bioorg. Med. Chem. Lett., 21, 3798 (2011); Yi, W., et al.: Eur. J. Med. Chem., 45, 639 (2010)

Applications M-PEG4-THIOL (cas# 52190-55-3) is a useful research chemical.

Applications 4-(1,3-thiazol-4-yl)phenol (cas# 68535-57-9) is a useful research chemical.

Applications (1S)-1-(adamantan-1-yl)ethan-1-ol (cas# 138309-12-3) is a useful research chemical.

Applications Cyclopentaneethanol is used in the prepartion of phenylalanine derivatives for incorporation into peptides as CD4 mimetic miniproteins interacting with HIV-1 surface glycoprotein. It is also used in the preparation of tertiary amine muscarinic receptor antagonists applied towards the treatment of chronic obstructive pulmonary disease.
References Morellato-Castillo, L. et al.: J. Med. Chem., 56, 5033 (2013); Glossop, P. et al.: J. Med. Chem., 54, 6888 (2011);

Applications 4-Butoxybutanol is used in the synthesis of biomedical polyurethane for application as scaffold materials.
References Liu, H. et al.: J. App. Polym. Sci., 117, 235 (2010);

Applications [4-(Trimethylammonium)benzyl] Alcohol Bromide is a compound useful in organic synthesis.

Applications Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.
References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976)

Applications 2-Nonyn-1-ol is a Propargyl alcohol (P762550) derivative that is used as a reagent to synthesize Microcarpalide, a microfilament disrupting agent that is weakly cytotoxic to mammalian cells. 2-Nonyn-1-ol is also thought to have potential antifungal properties.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gershon, H., et al.: J. Pharm. Sci., 73, 1840 (1984); Ratnayake, A., et al.: Org. Lett., 3, 3479 (2001); Tamao, K., et al.: Tetrahedron Lett., 29, 6955 (1988)

Applications 2H-1,3-benzodithiole-2-thione (cas# 934-36-1) is a useful research chemical.

Applications The toxicity of 4-Butoxybenzyl Alcohol has been studied on rapidly dividing cancer cells (L1210 leukemia).
References Kapur, S., et. al.: Chemosphere, 41, 1643 (2000)

Applications Tetrahydro-2H-pyran-2-ol (cas# 694-54-2) is a useful research chemical.

Applications Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);

Applications 4-Nitro-benzeneethanol is a useful synthetic intermediate. It can be used to synthesize N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptor. It can also be used to prepare 2-aza-2'-deoxyinosine-containing oligodeoxyribonucleotide duplexes.
References Piscitelli, F., et al.: J. Med. Chem., 55, 5627 (2012); Acedo, M., et al.: J. Org. Chem., 60, 6262 (1995)

Applications 10-Undecen-1-ol (cas# 112-43-6) is a useful research chemical.

Applications 3,3-DIPHENYLPROPANOL (cas# 20017-67-8) is a useful research chemical.

Applications Labelled Tert-butyl Alcohol is used as an organic solvent. Also it is used in the synthesis of proteosome inhibitors that are quite potent.
References Kawamura, S. et al.: J. Med. Chem., 56, 3689 (2013); Galy, N. et al.: Tetra. lett., 54, 2703 (2013);

Applications 1-Heptanol have also been used in the fragrance industry due to its pleasant smell.
References Ren, Q., et al.: J. Food. Agri. Environ., 10, 67 (2012); Mendes, C.E., et al.: Quimica. Nova., 35, 1787 (2012);

Applications 2-[(Tributylstannyl)methyl]-2-propen-1-ol is a useful reagent for organic synthesis.

Applications 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol is used in the preparation of fluorescent N/S acyl derivatives.
References 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)thio]ethanamine

Applications 23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery.
References Goswami, L. et al.: Org. Biomol. Chem., 11, 1116 (2013);

Applications 3,6-Dimethyl-3-heptanol (cas# 1573-28-0) is a compound useful in organic synthesis.

Applications 2-Aminothiophen-3-ol, is a heterocyclic building block used for the synthesis of various pharmaceutical compounds.

2,2-Dimethyl-1-propanol (DMPA) is an inorganic acid that can be used as a coagulant for wastewater treatment. It has been shown to be effective in removing malonic acid from water at pH 4.0 and below. The reaction mechanism of DMPA is not fully understood, but it is thought to involve the formation of a hydroxyl group on the methyl group of DMPA, which then reacts with the acid and releases hydrogen ions. The hydrogen ions react with sodium carbonate to form sodium bicarbonate and release water vapor. This process continues until all the DMPA has reacted or until there is no more acid present. Asymmetric synthesis of DMPA is possible using neopentyl alcohol and fatty acids as starting materials.

2-Butanol is a colorless liquid that has inhibitory properties against the enzyme activities of hydroxylase, acetaldehyde dehydrogenase, and alpha-ketoglutarate decarboxylase. 2-Butanol is used as an active antiretroviral therapy for HIV patients. It also acts as a solid catalyst in the hydrogenation of carboxylic acids. The reactivity of 2-butanol is due to its ability to form stable complexes with enzymes by hydrogen bonding interactions. This chemical can be used in kinetic studies and analytical methods, such as gas chromatography and mass spectrometry, which are used to identify the structure of the enzyme complex and analyze the reaction mechanism.

(aR)-a-[[[2-(4-Nitrophenyl)ethyl]amino]methyl]benzenemethanol is a chiral, carbonyl compound that has been used in the synthesis of mirabegron. It is synthesized by reacting an amide with a hydrochloric acid salt. The product yield of (aR)-a-[[[2-(4-Nitrophenyl)ethyl]amino]methyl]benzenemethanol is high and it does not react with aluminium or amide impurities. This compound can be used for the industrial synthesis of mirabegron, which is a drug for the treatment of urinary incontinence. The reduction reaction and hydrolysis reactions are both important to this process.

1-ethynyl-cyclohexan-1-ol is a silicon sealant that can be used in a variety of industries. 1-ethynyl-cyclohexan-1-ol has high resistance to water, oil and other chemical substances. 1-ethynyl-cyclohexan-1-ol is a molecule with the formula CH2CH(OH)CH2 and it is not soluble in water. It is also chemically stable and does not react with hydrochloric acid. The FTIR spectra show that the carbonyl group in 1-ethynyl cyclohexanone is present as an ester. The nmr spectra indicate that the substrate film contains methyl ethyl silicone and that there are no other components present.

4-Aminoquinoline-2-one is a nonsteroidal anti-inflammatory drug that has tuberculostatic activity. It binds to the nitrogen atoms of the enzyme dihydropteroate synthase, which is involved in the synthesis of folic acid and DNA. This leads to an increase in reactive oxygen species and inflammation, which causes disease activity. 4-Aminoquinoline-2-one has been shown to be synergistic with monoclonal antibodies when used as a treatment for inflammatory diseases. In order for 4-aminoquinoline-2-one to be taken up by cells, it must bind to cellular uptake proteins through hydrogen bonds or disulfide bonds.

Chromagnol is a drug that inhibits the enzyme protein kinase C (PKC). It has been shown to have inhibitory properties on cardiac muscle cells and whole-cell recordings of heart cells. Chromagnol has also been shown to affect the function of bowel disease, including papillary muscle. Chromagnol has been shown to have effects on cardiac and atrial tissue. This drug may be a potential treatment for autoimmune diseases, such as multiple sclerosis, or other diseases that are caused by PKC overactivity. The mechanisms of action are not fully understood but it is believed that chromanol binds to the cytosolic Ca2+ ion channel, preventing it from opening and releasing Ca2+, which leads to an increase in intracellular Ca2+.

3-Dehydro retinol is a carotenoid that is found in the skin. It is derived from retinol, and has been shown to have antioxidant properties. 3-Dehydro retinol can be isolated from the fungus Monascus purpureus by chromatographic methods. The enzyme activities of 3-dehydroretinol are not well understood, but it has been hypothesized that chronic exposure to this compound may lead to an increase in cell proliferation or an increase in cell differentiation. 3-Dehydro retinol has also been shown to inhibit the oxidation of other molecules such as hydrogen chloride.

Delta9,11-Estradiol is an estrogen that has been found to bind to the estrogen receptor α. The growth factor activity of this drug is mediated through the binding of this receptor and the activation of various intracellular signaling pathways. This drug is effective in treating eye disorders such as macular degeneration. Delta9,11-Estradiol also has a protective effect on ganglion cells by reducing oxidative stress, inhibiting apoptosis, and modulating inflammatory responses. The hydroxyl group in Delta9,11-Estradiol can be used as a corrosion inhibitor in eye drops and other ophthalmic solutions. It binds to viral gene promoters and inhibits transcriptional activity of these genes.

1,3-Difluoro-2-propanol is a hydrogen bond donor. It is used as an animal repellent and insecticide. It has been shown to be effective against the larvae of mosquitoes and flies. 1,3-Difluoro-2-propanol has also been found to be effective against some fungi, although it is not active against bacteria. The octanol/water partition coefficient (log Kow) of 1,3-difluoro-2-propanol is -0.86. 1,3-Difluoro-2-propanol has been shown to inhibit biochemical reactions in animals by inhibiting ATPase and phosphate uptake in mitochondria. This inhibition leads to the accumulation of metabolites such as lactic acid and pyruvic acid which are responsible for the symptoms seen with exposure to this chemical. 1,3-Difluoro-2-propanol has also been shown

3-Amino-2-methylpropan-1-ol is a reactive chemical that can be used as a reactant in the synthesis of other chemicals. It is an alkanolamine and can be found in small amounts in water vapor. 3-Amino-2-methylpropan-1-ol has been shown to have low energy and it reacts with water vapor to form 3,4-dihydroxybutanal, which is a product that can be converted into other useful chemicals. 3-Amino-2-methylpropan-1-ol also reacts with high energy photons to form new substances, such as 3,4,5,6 tetrahydroxymethylbenzaldehyde. 3Amino - 2 - methylpropan - 1 - ol has been shown to have many uses including the production of low molecular weight polymers and resins for paints and coatings.

Please enquire for more information about 4-Aminotetrahydrothiophene-3-ol 1,1-dioxide including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Hydroxy-7-methoxyquinoline is an anti-malarial drug that belongs to the class of trimethyl, trifluoromethyl group. It is a cyclic compound and its synthesis starts with cyclization of the methyl derivative, which forms a ring. This product is used in clinical practice as an inhibitor of malarial protozoa and has been shown to have mechanistic effects on the cytochrome bc1 complex containing red blood cells. 4-Hydroxy-7-methoxyquinoline also inhibits the growth of bacteria by binding to the enzyme methionine synthase, which is involved in the biosynthesis of methionine from homocysteine. The product also has an inhibitory effect on DNA synthesis and protein synthesis.

Dihydrotestosterone is a potent androgen that is used in hormone replacement therapy to treat conditions such as testosterone deficiency, delayed puberty, and impotence. It is also used to treat breast cancer in women and prostate cancer in men. Dihydrotestosterone binds to the androgen receptor, which alters the expression of genes by altering their nucleotide sequences. It has been shown to have anti-tumor effects on prostate cells in vitro, but not on breast or ovarian carcinoma cell lines. The drug has been shown to be active against HIV replication in cell culture models.

Rac-1,2-bis-palmitoyl-3-chloropropanediol is a dispersive molecule that is composed of a fatty acid and a chlorinated derivative of palmitic acid. It is used to calibrate the mass spectrometer and as an internal standard in quantitative analysis. Rac-1,2-bis-palmitoyl-3-chloropropanediol reacts with electrospray ionization with a dose-dependent response. It has been shown to be toxic to kidney cells at high doses but not at low doses. This chemical has been detected in food samples after being absorbed from the gastrointestinal tract. Rac 1,2-bis-palmitoyl 3 chloropropanediol can be found in the dipalmitate form or as formic acid.

Please enquire for more information about {1-[2-(4-Methylphenoxy)ethyl]-1H-benzimidazol-2-yl}methanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about (1-Benzyl-1H-benzimidazol-2-yl)methanol including the price, delivery time and more detailed product information at the technical inquiry form on this page

3,29-Dibenzoyl rarounitriol (3,29-DBR) is a quercetin glycoside that has been shown to be an effective inhibitor of the H1 receptor. It prevents the binding of histamine to the H1 receptor on cells, preventing the release of inflammatory compounds such as lysosomal enzymes and prostaglandins. 3,29-DBR has been shown to be a potent inhibitor of terfenadine in both rats and humans. It has also been shown to inhibit other drugs metabolized by cytochrome P450 2D6. In a pharmacokinetic study in rats, 3,29-DBR was found to have a half-life of 5 hours and peak plasma concentrations at 1 hour following oral administration. Pharmacokinetic parameters are dose dependent with Cmax values ranging from 0.5 µg/mL for low doses to 14 µg/mL for high doses.

T2 toxin triol is a bacterial strain that is used as a model system for the study of zearalenone. It has been shown to inhibit the growth of trifluoroacetic acid-treated cells and prevent the formation of glucuronide conjugates. T2 toxin triol has also been shown to be toxic to rat liver microsomes in vitro, but not to tissue culture or monoclonal antibody-transfected cells. The toxicity was found to be due to its basic structure, which causes an increase in intracellular levels of reactive oxygen species and lipid peroxidation.

5-Ethyl-2-pyridineethanol is an anti-diabetic drug that belongs to the class of thiazolidinediones. It is the active form of pioglitazone, which has been shown to bind to peroxisome proliferator-activated receptor gamma (PPARγ). This binding results in increased expression and activity of insulin receptors on cell membranes. 5-Ethyl-2-pyridineethanol also binds to PPARγ in a similar manner as pioglitazone, and it has been shown to be an agonist for PPARγ. This compound has a number of other biological effects such as inhibition of the production of acetone by the liver, which is due to its ability to inhibit diazotization.