Amines

<p>5-FAM SE, a single-isomer green fluorophore, labels peptides, proteins, nucleotides.</p>

<p>BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive</p>

<p>Fluorescamine (Ro 20-7234) non-fluorescent; reacts with amines, forming bright products; detects amines, peptides.</p>

<p>5(6)-TAMRA SE (5(6)-Carboxytetramethylrhodamine N-succinimidyl ester) is the amine-reactive, mixed isomer form of TAMRA.</p>

<p>5(6)-CFDA: cell-permeable, esterase-responsive viability probe; fluoresces upon activation, indicating enzymatic activity and membrane integrity.</p>

<p>Applications [4-[[4-(dimethylamino)phenyl]-(4-dimethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]phenyl]-trimethylazanium;dichloride (cas# 82-94-0) is a useful research chemical.<br></p>

<p>Applications Chloramine-T Trihydrate is used as a safe and convenient electrocyclisation (oxidizing) agent in the preparation of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mal, S., et al.: Tetrahedron Lett., 56, 2896-2901 (2015)<br></p>

<p>Applications 2-AMINO-5,6-DIMETHYLBENZOTHIAZOLE (cas# 29927-08-0) is a useful research chemical.<br></p>

<p>Applications 3-Aminobiphenyl<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N,N-Dimethyldecylamine is a useful synthetic intermediate. It can be used to prepare emodin (E523000) quaternary ammonium salt derivatives as potential anticancer agents It is also a reactant used to synthesize Benzyldecyldimethylammonium chloride (B234550), a biocide.<br>References Wang, W., et al.: Eur. J. Med. Chem., 56, 320 (2012); Qiu, B., et al.: Zhongguo Yaowu Huaxue Zazhi, 20, 353 (2010); Shao, J., et al.: Eur. J. Med. Chem., 56, 308 (2012); Lee, M., et al.: Appl. Micro. Biotech., 87, 1109 (2010)<br></p>

<p>Applications 5-Amino-2-phenyl-3(2H)-pyridazinone (cas# 13589-77-0) is a useful research chemical.<br></p>

<p>Applications Aminophenyltrimethoxysilane is a useful intermediate for the preparation of aromatic silanes as high thermal stability coupling agents.<br>References Pan, Y., et al.: Adv. Mat. Res., 690, 1483 (2013)<br></p>

<p>Applications 3-(methylamino)-3-oxopropanoic acid (cas# 42105-98-6) is a useful research chemical.<br></p>

<p>Applications 1-Phenyl-2-butanamine (cas# 30543-88-5) is a useful research chemical.<br></p>

<p>Applications Triethylamine Trihydrofluoride is used in the synthesis of modified siRNA’s in vivo used to inhibit hepatitis B replication (1). Used in RNA synthesis in the removal of t-butyldimethylsilyl protection (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Marimani M. et al.: Bioorg Med Chem. 2013 Oct 15;21(20):6145-55. 2. Westman, E. et al.: Nucleic Acids Res. 1994 Jun 25;22(12):2430-1<br></p>

<p>Applications 2-(2-Aminoethylamino)ethanol is a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Its used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013);<br></p>

<p>Applications 2-Amino-2,3-dimethylbutyramide is an important intermediate in the synthesis of potent imadazoline herbicides. In addition, it is used to prepare new chiral ligands.<br>References Lin, Z. et al.: J. Ind. Microbiol. Biotech., 39, 133 (2012); Lin, Z. et al.: Biotech. Lett., 33, 1809 (2011); Sedlak, M. et al.: Tetra. Lett., 45, 7723 (2004);<br></p>

<p>Applications 4-Amino-6-(tert-butyl)-3-mercapto-4,5-dihydro-1,2,4-triazin-5-one (cas# 33509-43-2) is a useful research chemical.<br></p>

<p>Applications 6-Aminobenzothiazole is a useful intermediate in synthesizing N-phenyl-substituted and di-substituted guanidinyl benzothiazole derivatives. These derivatives act as antimicrobial and antioxidant agents.<br>References Mahesh, B., et al.: Res. Chem. Intermed., 42, 6195 (2016)<br></p>

<p>Applications Tributylamine is used as a reagent in the syntheses of quaternary ammonium-containing trithiocarbonate RAFT agents and hemi-telechelic cationomers. Tributylamine is also used as a corrosion inhibitor for mild steel in hydrochloric acid and as an initiator for cracking of heptane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhang, L., et al.: Polymer Chem., 5, 1180 (2014); Bastidas, J.M., et al.: J. Mater. Sci., 35, 2637 (2000); Wang, Z., et al.: Energ. Conver. Manage., 49, 1584 (2008)<br></p>

<p>Stability Hygroscopic<br>Applications N-​Ethyl-​α-​methyl-​3-​(trifluoromethyl)​-benzeneethanamine hydrochloride has been used in case studies for the study of impulsivity, motor skills, and anxiogenic effects in the neuroscience community.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Whitney, K.N., et al.: Exp. Clin. Psychopharm., 21, 345-54 (2013); Arrant, A.E., et al.: Neuropharmacology, 65, 213-22 (2013)<br></p>

<p>Applications N-(5-Aminopentyl)acetamide is an acetylated polyamine, a promising biochemical marker for cancer and many other pathophysiological conditions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hakkinen, M. R., et al.: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci., 941, 81 (2013); Paik, M., et al.: Clin. Chim. Acta, 411, 1532 (2010)<br></p>

<p>Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.<br>References Kono, K. et al.: J. Antibiot., 53, 759 (2000);<br></p>

<p>Applications N-(2-(2,4,6-TRICHLOROPHENOXY)ETHYL)PROPAN-1-AMINE (cas# 67747-01-7) is a useful research chemical.<br></p>

<p>Applications Dimethyl Aminoterephthalate is used to prepare imidazotetrazinones as probes for action of temozolomide. It can be used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity.<br>References Clark, A., et al.: J. Med. Chem., 38, 1493 (1995); Jacobs, R., et al.: Bioorg. Med. Chem. Lett., 5, 2879 (1995)<br></p>

<p>Applications Hydrochloride salt of benzyltriethylammonium which acts as a phase-transfer catalyst in chemical reactions.<br>References Shi, Z. et al.: Chem. Sci., 4, 829 (2013); Landeros, J. et al.: J. Mol. Struct., 1037, 412 (2013);<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Applications 4-Aminoantipyrine (cas# CAS:83-07-8) is a useful research chemical.<br></p>

<p>Applications N-(Benzyloxycarbonyl)ethanolamine is an intermediate used to prepare alkynylaryladenines as A2A adenosine receptor agonists and effects on hepatic glucose production. It is also used in the synthesis of functionalized N-arylaminoethyl amides as noncovalent inhibitors of cathepsin S.<br>References Harada, H., et al.: Bioorg. Med. Chem., 9, 2709 (2001); Tully, D., et al.: Bioorg. Med. Chem. Lett., 16, 5112 (2006)<br></p>

<p>Applications Benzyltrimethylammonium Hydroxide is a reagent used in the preparation of dithiocabamates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zaidi, S. et al.: Chem. Biol. Interface., 7, 166 (2017);<br></p>

<p>Applications α-Isopropylbenzylamine Hydrochloride is used in the synthetic preparation of arylalkylamines by addition of Grignard reagents to phosphorylaldimines.<br>References Zwierzak, A., Napieraj, A.: Synthesis, 6, 930 (1999)<br></p>

<p>Applications 1-aminoindan (cas# 34698-41-4) is a useful research chemical.<br></p>

<p>Applications Butylamine Hydrochloride is a miscellaneous reagent used in the synthesis of benzamides for the synthesis of various drugs and polymers.<br>References Bantreil, X. et al.: Eur. J. Org. Chem., 2015, 416 (2015);<br></p>

<p>Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.<br>References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)<br></p>

<p>Stability Hygroscopic<br>Applications O-AMINOPHENOL SULFATE (cas# 67845-79-8) is a useful research chemical.<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Applications Dimethylammonium Dimethylcarbamate is a reactant used in the synthesis of vanadium complex implantation on silica surfaces and may be studied for its use in phrmaceutical synthesis.<br>References Bresciani, G. et al.: Eur. J. Inorg. Chem., 10, 1176 (2018);<br></p>

<p>Applications N,N-Dimethylhexadecylamine is used in the synthesis of 3-(N,N-Dimethylpalmitylammonio)propanesulfonate (D461825), a zwitterionic surfactant used in the preparation of a highly efficient adsorbent for herbicides, DHAPS-Mt.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gu, Z., et. al.: Ind. Eng. Chem. Res., 54, 4947 (2015)<br></p>

<p>Applications N,N,N',N'-Tetramethylethylenediamine is used as polymerization accelerator in gel electrophoresis, solvent and oxidizing reagent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bassam, B.J., et al.: BioTechniques, 19, 568 (1995), Moham, D., et al.: J. Chromatogr., 979, 271 (2002),<br></p>

<p>Stability Hygroscopic<br>Applications N-(2-Chloroethyl)-1,2-ethanediamine Dihydrochloride is an analog of 2-(2-Aminoethylamino)ethanol (A608990); a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Also used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013)<br></p>

<p>Applications N-[(4-chlorophenyl)methyl]cyclopentanamine is a useful reagent for the preparation of γ-​lactams.<br>References Fujii, T., et al.: Tetrahedron Letters, 61, 152276 (2020)<br></p>

<p>Applications 6-Amino-5-1,3-dimethyl-5-(formamido)uracil is a substitued uracilic metabolite of methylxanthine and is also a metabolite of Theophylline (T343850). 6-Amino-5-1,3-dimethyl-5-(formamido)uracil has been used for the synthesis of 8-arylaminotheophyllines.<br>References Peri, G., et. al.: Toxicol. Lett., 18, 133 (1983); Celardo, A., et. al.: Eur. J. Drug Metab. Ph., 10, 279 (1985); Senga, K., et. al.: J. Heterocyclic Chem., 15, 641 (1978)<br></p>

<p>Applications Ethylamine Solution is used as a reagent in the synthesis of a series of hexadentate ligands as potential antibacterial agents. Also used as a reagent in the synthesis of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.<br>References Zhang, M., et al.: Chem. Biol. Drug Des., 84, 659 (2014); Ma, H., et al.: Eur. J. Med. Chem., 89, 721 (2015)<br></p>

<p>Applications 4-Dimethylaminosulfotoluidide is an intermediate in the synthesis of Tolylfluanide (T536730), a polyvalent sulfamide fungicide that is closely related to dichlofluanide.<br>References Wainwright, A. et al.: Bright. Crop Prot. Conf. Pests Dis., 1, 275 (1996)<br></p>

<p>Applications 2-(2-Aminoethoxy)ethanol is a widely used reactant that has been used in the preparation of TD-4306 as long-acting β2-agonist for asthma and COPD therapy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mckinnell, R.M., et. al.: Bioorg. Med. Chem. Lett., 24, 2871 (2014)<br></p>

<p>Applications Dibenzylamine, a chemical contaminant in L-(+)-β-hydroxybutyrate, exhibits direct anticonvulsant actions in vivo.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rho, J.M., et al.: Epilepsia, 43, 358 (2002)<br></p>

<p>Applications Cyanomelamine is an substituted Melamine (M208700), an compound that forms synthetic resins with formaldehyde.<br>References LaBrecque, G.C., et al.: J. Econ. Entomol., 61, 1621 (1968);<br></p>

<p>Applications 2-(4-Diethylamino-2-hydroxybenzoyl)benzoic Acid<br></p>

<p>Applications Diisopropanolamine is used as a reagent in the synthesis of pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors.<br>References Kravchenko, D., et al.: Lett. Drug Des. Discov., 3, 61 (2006)<br></p>

<p>Applications N,N-Dicyclohexylmethylamine is used as a reagent in the base preparation of 13C2- and 2H phenethylamines as internal standards for IDMS by Pd-catalyzed double carbonylation of aryl iodides in the presence of amine nucleophiles followed by deoxygenation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nielsen, D., J. Org. Chem., 74, 6155 (2012)<br></p>