Amines

<p>5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) contains a carboxylic acid that can be used to react with primary amines via carbodiimide</p>

<p>NBD-F (4-Fluoro-7-nitrobenzofurazan) is a fluorescent derivatization compound for amino acid analysis.</p>

<p>BI-1467335 HCl(BI 1467335) is a selective, orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) that helps improve chronic obstructive</p>

<p>Stability Hygroscopic<br>Applications Ammonium oxalate is used as an analytical reagent and general reducing agent. It is commonly employed in soil chemical analysis to extract iron and aluminum from poorly-crystal line minerals.<br>References Seyed, D., et al.: J. Photo. Chem., 394, 112486 (2020); Blanchard, F., et al.: Cryst. Growth Des., 18, 4593-4601 (2018)<br></p>

<p>Applications 1,3,5-Tris(4-aminophenyl)benzene (cas# 118727-34-7) is a useful reagent for catalytic asymmetric synthesis of chiral covalent compounds.<br>References Wang, J., et al.: J. Am. Chem. Soc., 142, 16915 (2020)<br></p>

<p>Stability Hygroscopic<br>Applications Used as an intermediate in the industrial preparation of non-ionic X-ray contrast agents such as Iohexol (I729500), Ioversol (I737000), Ioxilan (I737500), Iopamidol (I735600).<br>References Rongved, P., et al.: Carbohydrate Res., 297, 325 (1997),<br></p>

<p>Applications Ethylenediamine Dihydrochloride (cas# 333-18-6) is a useful research chemical.<br></p>

<p>Applications 4-Amino-6-(tert-butyl)-3-mercapto-4,5-dihydro-1,2,4-triazin-5-one (cas# 33509-43-2) is a useful research chemical.<br></p>

<p>Applications tert-Butyl [(1R,2S,5S)-2-Amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate Oxalate is a starting material and useful building block of various pharmaceuticals.<br></p>

<p>Stability Hygroscopic<br>Applications 1-Adamantanamine Sulfate (cas# 31377-23-8) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 4-(2-Aminoethyl)benzene-1,2-diol has been studied for its role in Parkinson's disease.<br>References Segura-Aguilar, J.: Neural Regeneration Research, 12, 897 (2017)<br></p>

<p>Applications N-(Benzyloxycarbonyl)ethanolamine is an intermediate used to prepare alkynylaryladenines as A2A adenosine receptor agonists and effects on hepatic glucose production. It is also used in the synthesis of functionalized N-arylaminoethyl amides as noncovalent inhibitors of cathepsin S.<br>References Harada, H., et al.: Bioorg. Med. Chem., 9, 2709 (2001); Tully, D., et al.: Bioorg. Med. Chem. Lett., 16, 5112 (2006)<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Applications 2-Amino-2,3-dimethylbutyramide is an important intermediate in the synthesis of potent imadazoline herbicides. In addition, it is used to prepare new chiral ligands.<br>References Lin, Z. et al.: J. Ind. Microbiol. Biotech., 39, 133 (2012); Lin, Z. et al.: Biotech. Lett., 33, 1809 (2011); Sedlak, M. et al.: Tetra. Lett., 45, 7723 (2004);<br></p>

<p>Stability hygroscopic<br>Applications 3-Amino-1-propanol is used in the synthesis of tetrathiafulvalenes displaying optical and electrochemical properties. Also used in the synthesis of lipid-like materials for the delivery and encapsulation of RNAi therapeutics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ignatenko, E. et al.: Russ. J. Org. Chem., 49, 1379 (2013); Akinc, A. et al.: Nat. Biotech., 26, 561 (2008);<br></p>

<p>Applications Benzylamine has been used as a reactant in the preparation of diacetylated benzylamide which has shown to induce a G1/G0 arrest in tumor cells and cytotoxicity against human ovarian cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Siewert, B., et. al.: Bioorg. Med. Chem., 22, 594 (2014)<br></p>

<p>Applications Dimethyl Aminoterephthalate is used to prepare imidazotetrazinones as probes for action of temozolomide. It can be used to prepare aminoquinazolines with neurokinin-2 receptor antagonist activity.<br>References Clark, A., et al.: J. Med. Chem., 38, 1493 (1995); Jacobs, R., et al.: Bioorg. Med. Chem. Lett., 5, 2879 (1995)<br></p>

<p>Applications A reagent used for the synthesis of hydroxylamines and hydroxyamates.<br>References Magin, D.F., et al.: J. Chromatogr., 178, 219 (1979), Safavy, A., et al.: Bioconjug. Chem., 13, 327 (2002),<br></p>

<p>Applications Ethylamine Solution is used as a reagent in the synthesis of a series of hexadentate ligands as potential antibacterial agents. Also used as a reagent in the synthesis of tetrahydrothiazolopyridine derivatives as potent smoothened antagonists.<br>References Zhang, M., et al.: Chem. Biol. Drug Des., 84, 659 (2014); Ma, H., et al.: Eur. J. Med. Chem., 89, 721 (2015)<br></p>

<p>Stability Hygroscopic<br>Applications Benzyltrimethylammonium chloride (cas# 56-93-9) is a useful research chemical.<br></p>

<p>Applications Ammonium Nonanoate is the salt form of n-Nonanoic Acid (N649385), which is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. It is also used in the preparation of plasticizers and lacquers.<br>References Pline, W., et al.: Weed Technol., 14, 667 (2000); Frade, J., et al.: Anal. Bioanal. Chem., 395, 2167 (2009);<br></p>

<p>Applications IHydroxylamine, is a useful reactant used that is mainly used as a reducing agent in organic reactions.<br></p>

<p>Applications N-Nitrosodipropylamine is a a N-nitrosamine derivative. The mutagenic activities of the carcinogenic N-nitrosamines were studied on both S. typhimurium TA100 and TA98, revealing moslty mutagenic activities on TA100 with few exceptions on TA98 (1). Water contaminant (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Yahagi, T. et al.: Mutat. Res. Fund. Mol. Mech. Mut. 1977. Apr:48(2) p121-1292. Mestankova, H. et al.: Water Res. 2016 Apr 15;93:110-20<br></p>

<p>Applications 1,3-Benzenedimethanamine (cas# 1477-55-0) is a useful research chemical.<br></p>

<p>Applications Tert-butyl 4-Aminobutanoate Hydrochloride is used as a substance in the prevention of drug-induced memory impairement by immunopharmacotherapy.<br>References Treweek, J. B., et al.: J. Med. Chem., 51, 6866 (2008)<br></p>

<p>Applications Ethanolamine is used in the preparation of various pharmaceutical compounds and inhibitors. Substituted carboxamides are synthesized using Ethanolamine that show potent antitumor activity. Also used in the synthesis of aminoquinolones which display anti-plasmodial activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);<br></p>

<p>Applications 2-Amino-2-thiazoline (cas# 1779-81-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Triethylamine Trihydrofluoride is used in the synthesis of modified siRNA’s in vivo used to inhibit hepatitis B replication (1). Used in RNA synthesis in the removal of t-butyldimethylsilyl protection (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Marimani M. et al.: Bioorg Med Chem. 2013 Oct 15;21(20):6145-55. 2. Westman, E. et al.: Nucleic Acids Res. 1994 Jun 25;22(12):2430-1<br></p>

<p>Applications [4-[[4-(dimethylamino)phenyl]-(4-dimethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]phenyl]-trimethylazanium;dichloride (cas# 82-94-0) is a useful research chemical.<br></p>

<p>Applications 6-[(6-Aminohexyl)amino]-6-oxo-hexanoic acid is a nylon oligomer with flame retardant properties.<br>References Zahn, Helmut et al.: Chemische Berichte, 92, 1381 (1959)<br></p>

<p>DEAC, SE (7-Diethylaminocoumarin-3-carboxy acid) is a blue fluorescent dye for labeling amine-containing organisms. λex of DEAC, SE is 330 nm and λem is 402</p>

<p>Applications 1,3-Diethyl-6-aminouracil (cas# 41740-15-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Aminobutanol is used in the preparation of CDK inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, J. et al.: Chin. J. Chem., 31, 1181 (2013); Tahghighi, A. et al.: J. Enz. Inhib. Med. Chem., 28, 843 (2013);<br></p>

<p>Applications 4-(diethylamino)benzophenone (cas# 18127-87-2) is a useful research chemical.<br></p>

<p>Applications Has a DNA binding effect.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mikata, Y., et al.: Chem. Pharm. Bull., 48, 477 (2000),<br></p>

<p>Impurity Brimonidine EP Impurity C<br>Applications 6-Quinoxalinamine is used in the synthetic preparation and evaluation of novel nitroheterocyclic hypoxic markers for solid tumor.<br>References Zhu, W., et al.: Bioorg. Med. Chem., 16, 3255 (2008)<br></p>

<p>Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.<br>References Kono, K. et al.: J. Antibiot., 53, 759 (2000);<br></p>

<p>Applications 2-(Acetylamino)-N-(phenylmethyl)propanamide, has shown to have anticonvulsant activity in vitro. Likely an impurity in the medication Lacosamide, (L098500).<br>References Martinez, J C. et al: MATCH, Vol. 67, issue 3, P: 745-758 (2012);<br></p>

<p>Applications 2,4-DIAMINOPTERIDINE-6-CARBOXYLIC ACID (cas# 716-74-5) is a useful research chemical.<br></p>

<p>Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.<br>References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);<br></p>

<p>Applications 5-Hydroxytryptamine (cas# 50-67-9) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3,4-Diaminoanisole (cas# 102-51-2) is a compound useful in organic synthesis.<br></p>

<p>Stability Light and Mositure Sensitive<br>Applications An amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Y. et al.: Anal. Bioanal. Chem., 400, 2141 (2011); Du, D. et al.: Anal. Chem., 82, 2989 (2010);<br></p>

<p>Applications Cetyltrimethylammonium hydrogensulfate 99% (cas# 68214-07-3) is a useful research chemical.<br></p>

<p>Applications 3-(1-Azepanyl)-1-propanamine refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases.<br>References Radic, Z., et al.: J Biol Chem, 287, 11798 (2012)<br></p>

<p>Applications Methyl 5-Aminopentanoate Hydrochloride is used as a reactant to synthesize several compounds with therapeutic potential.<br>References Larson, Peter, et al.: ACS Med. Chem. Let, 8(11), 1148-1152 (2017);Li, Yongtao, et al.: J. of Med. Chem., 61(7), 3166-3192 (2018);Lu, Yuzhi, et al.: ACS Med. Chem. Let., 7(12), 1185-1190 (2016)<br></p>

<p>Applications O-Benzylhydroxylamine (cas# 622-33-3) is a useful research chemical.<br></p>