Ethers

<p>Applications 4,5-Dimethoxy-2-nitrobenzoic Acid (cas# 4998-07-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Tetraethyl Orthocarbonate is used in the synthesis of chemokine receptor-5 inhibitors against HIV-1. Also used in the synthesis of benzobisoxazoles used in the preparation of organic semiconductors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kazmierski, W. et al.: J. Med. Chem., 54, 3756 (2011); Mike, J. et al.: Org. Lett., 10, 4915 (2008);<br></p>

<p>Applications 5-(Ethoxycarbonyl)thiophene-3-boronic Acid is a useful reagent for preparing hydroxyimino(phenyl)propanones as GPBAR1 agonists.<br>References Bissantz, C., et al.: U.S. Pat. Appl. Publ. (2012), US 20120010190 A1<br></p>

<p>Applications 4-(2-Ethoxy-2-oxoethoxy)phenylboronic acid<br></p>

<p>Applications Diethyl 3,5-Dimethoxybenzylphosphonate (cas# 108957-75-1) is a compound useful in organic synthesis.<br></p>

<p>Applications A useful wittig reagent.<br></p>

<p>Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br></p>

<p>Applications (2,3,4-Trimethoxyphenyl)boronic Acid is a reagent used in the synthesis of heteroaryl, mono and bicyclic compounds which may be used as inhibitors for EGF and PDGF receptor tyrosine kinases. Also used in the synthesis of non-steroidal CYP 17 inhibitors in the treatment of prostate cancer<br>References Hutschenreuter, T. et al.: J. Enz. Inhib. Med. Chem., 19, 17 (2004);<br></p>

<p>Applications 4,4-Diethoxy-N,N-diethyl-1-butanamine is a useful reagent for the synthesis of amino acetals.<br>References Keglevic, D., et al.: Croat. Chem. Acta, 35, 175(1963)<br></p>

<p>Applications 4,4-Dimethoxybutan-1-ol is a reactant used in the preparation of tetrahydropyranols and hydropyranooxepans.<br>References Hoffmann, R.W., et. al.: New J. Chem., 25, 102 (2001)<br></p>

<p>Stability Light Sensitive<br>Applications Cis-1-Bromo-2-ethoxyethylene<br></p>

<p>Applications tert-Butyl (2-(methoxy(methyl)amino)-2-oxoethyl)carbamate has been used as a reactant in the preparation of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 with potential use in osteoarthritis therapy.<br>References Durham, T.B., et. al.: J. Med. Chem., 57, 10476 (2014)<br></p>

<p>Applications 2-((Tetrahydrofuran-2-yl)methoxy)phenoxy)tetrahydro-2H-pyran is an intermediate used in the synthesis of Bufetolol (B689435), a β-adrenergic blocking agent and it inhibits the activation of adenyl cyclase.<br>References Ikegami, K., and Imamura, H.: Yakugaku Zasshi 96, 614 (1976); Yamaji, A., et al.: Yakugaku Zasshi 105, 1179 (1985)<br></p>

<p>Applications trans-3,4,5,4'-Tetramethoxystilbene (cas# 134029-49-5) is a useful research chemical.<br></p>

<p>Applications (3,3-diethoxypropyl)dimethylamine (cas# 16851-30-2) is a useful research chemical.<br>References Choi, G., et al.:Angew. Chem. Int. Ed., 57,6166(2018)<br></p>

<p>Applications Tetramethoxymethane has application within an electrolyte solution for the use of rechargeable lithium batteries. It has also been used as a reactant in the synthesis of novel anti-HIV-1 compounds.<br>References Cadger, T.G. et al.: Proc. Electrochem. Soc., 88, 699 (1988); Kazmierski, W.M. et al.: J. Med. Chem., 54, 3756 (2011);<br></p>

<p>Applications Dimethoxy(methyl)silane (cas# 16881-77-9) is a useful research chemical.<br></p>

<p>Applications 2,5-Dimethoxybenzyl Alcohol can be used as a self-indicating standard for the determination of organolithium reagents<br>References Winkle, M.R. et al.: J. Chem. Soc. Chem. Comm., 3, 1980 (1980):<br></p>

<p>Applications Intermediate in the production of modified guanine derivatives<br>References Kim, S., et al.: J. Med. Chem., 21, 883 (1978),<br></p>

<p>Applications N-[1-[3-(2-Ethoxyphenyl)-2,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl]acetamide is an intermediate in the synthesis of Vardenafil (V098001) related compounds.<br>References Olszewska, T., et al.: Tetahedron., 69, 474 (2013);<br></p>

<p>Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.<br>References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)<br></p>

<p>Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Ethoxymethyl)furan (cas# 6270-56-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Nitro-2-[(1E)-2-nitroethenyl]-4-(phenylmethoxy)-benzene is an intermediate used in the synthesis of 5-Hydroxyindole-3-acetic acid (H953605), which is an impurity of chlorpheniramine (C424300), an antihistaminic agent.<br>References Josko, J., et al.: Annal. Acad. Med. Siles., 66, 13, (2012); Carson, R.P., et al.: Human. Molec. Genetics., 22, 140 (2013);<br></p>

<p>Applications 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol (cas# 77544-60-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2-Ethoxy-4-ethoxysulfonylbenzoic Acid is a derivative of Methyl 2-Ethoxybenzoate (M220113), a useful chemical reagent, used in the synthesis and antibacterial triazoles and oxadiazoles, as well as sulfonamide compounds.<br>References Shi, Z. et al.: Compt. Rend. Chim., 18, 1320 (2015);<br></p>

<p>Applications (3,5-Dimethoxyphenyl)acetonitrile (cas# 13388-75-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 7,8-Dimethoxy-1,3-dihydro-2H-3-benzazepin-2-one is a substituted benzazepinonee derivative used in the preparation of bradycardic agents as well as isoform-selective f-current blockers.<br>References Liang, H.-Y. et al.: Arch. Pharm., 343, 114 (2010); Reiffen, M. et al.: J. Med. Chem., 33, 1496 (1990); Melchiorre, M. et al.: J. Med. Chem., 53, 6773 (2010);<br></p>

<p>Applications 2,3-Dimethoxyphenol (cas# 5150-42-5) is a useful research chemical.<br></p>

<p>Applications Bis[2-(2-chloroethoxy)ethyl] Ether, is an impurity in the synthesis of 2-[2-[2-(2-Chloroethoxy)ethoxy]ethoxy]ethanol (C365875), which is a polyethylene glycol used in the synthesis of novel glycolipids that bind HIV-1 cell surface glycoprotein Gp120 with potential application to pharmaceutical HIV-1 drugs. Also used in the synthesis of PET imaging agents targeting brain β-amyloid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References LaBell, R. et al.: Bioconj. Chem., 13, 143 (2002); Zhang, W. et al.: Nucl. Med. Biol., 32, 799 (2005);<br></p>

<p>Stability Hygroscopic<br>Applications Ethyl 3,3-diethoxypropionate<br></p>

<p>Applications 2,3-Dimethoxyaniline (cas# 6299-67-8) is a useful research chemical.<br></p>

<p>Applications 3,5-Dimethoxyaniline (cas# 10272-07-8) is a compound useful in organic synthesis.<br></p>

<p>Applications o-Carbomethoxybenzyl Sulfonamide is a useful reactant in organic synthesis.<br>References Jiang, Lin, et al.: Youji Huaxue, 26(2), 203-206 (2006)<br></p>

<p>Applications 2-[2-(2-Propynyloxy)ethoxy]ethanol is a reactant used in the preparation of divalent ligands based on 3-deoxy-4-thiolactose as inhibitors of E. coli β-galactosidase.<br>References Cagnoni, A.J., et. al.: Org. Biomol. Chem., 11, 5500 (2013)<br></p>

<p>Applications Methyl 2-Ethoxy-5-(ethoxysulfonyl)benzoate is a useful research chemical.<br></p>

<p>Applications Methyl Dimethoxyacetate is used as a reagent in the synthesis of benzimidazole derivatives for use as respiratory syncytial virus inhibitors.<br>References Cooymans, Ludwig Paul; D., et al. PCT Int. Appl. WO 2012080446 A1 20120621. Jun 21, 2012<br></p>

<p>Stability Hygroscopic<br>Applications [3-(3,4-dimethoxyphenyl)propyl](methyl)amine hydrochloride (cas# 83979-31-1) is a useful research chemical.<br></p>

<p>Applications Methyl Methoxyacetate is a reagent used in the synthesis of diphenylamine-terepthalaldehyde resins which maybe be used as a catalyst for tetrahydropyranylation.<br>References Tanemura, K. et al.: Org. Prep. Proc. Int., 48, 72 (2016); By: Robiette, R. et al.: J. Am. Chem. Soc., 138, 737 (2016);<br></p>

<p>Applications Synthesis and receptor binding of 5-(amino[3H]2methyl)-3-isothiazolol ([3H]thiomuscimol), a specific GABAA agonist photoaffinity label.<br>References Frolund, B., et al.: J. Labelled Compounds Radiopharm., 36, 877 (1995),<br></p>

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Stability Volatile<br>Applications Methoxytrimethylsilane (cas# 1825-61-2) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (E)-1,1-Dimethoxybut-2-ene is a useful research chemical for organic synthesis and other chemical processes.<br>References Huot, J. F., et al.: Chem. Lett., 9, 1599 (1991); Mathew, S., et al.: Process Biochem., 501985 (2015)<br></p>

<p>Applications Methyl 3-hydroxy-4,5-dimethoxybenzoate (cas# 83011-43-2) is a useful research chemical.<br></p>

<p>Applications Methyl 2-Acetyl-4,4-dimethoxybutanoate is a useful reagent for organic synthesis.<br>References Herrmann, J. L., et al.: Tetrahedron Lett., 47, 4711 (1973)<br></p>

<p>Applications 2,2-Diethoxy-N-ethylethanamine is used in the preparation of 1-substituted-2-mercaptoimidazoles with antithyroid activity.<br>References Jones, R.G.J. Am. Chem. Soc., 71, 4000 (1949)<br></p>

<p>Applications Reagent used in Phthalimidooxy alylation.<br>References Yoda, R., et al.: Chem. Pharm. Bull., 42, 686 (1994), Kim, M., et al.: Bioorg. Med. Chem. Lett., 6, 2077 (1996),<br></p>

<p>Applications Methyl 2-Amino-3,4,5-trimethoxybenzoate could be a constituent contributing to the aroma of green tea leaves.<br>References Hasegawa, T., et al.: J. Food Eng., 4, 10 (2014)<br></p>

<p>Stability Store at -20°C under Argon. Air Sensitive.<br>Applications 5,5-Diethoxypentanal (cas# 79893-96-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4'-Dimethoxybenzhydrol acts as a reagent in the preparation of aryloxyacetamide derivatives and their biological activity as neuroprotective agents. Preparation and anticancer activity of quebecol and analogs.<br>References Zhong, Y., et al.: Bioorg. Med. Chem. Lett., 26, 2526 (2016); Pericherla, K., et al.: Bioorg. Med. Chem. Lett., 23, 5329 (2013)<br></p>

<p>Applications Ethoxyacetic acid<br></p>

<p>Applications 2-(2-Ethoxyphenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4(1H)-one is an intermediate in the synthesis of Vardenafil (V098001) related compounds.<br>References Haning, H., et al.: Bioorg. Med. Chem. Lett., 15, 3900 (2005); Olszewska, T., et al.: Tetrahedron., 69, 474 (2013);<br></p>

<p>Applications 1-[2-Hydroxy-4,6-bis(ethoxymethoxy)phenyl]ethanone (cas# 128837-25-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4'-Dimethoxydiphenylamine is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4'-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.<br>References Kel'man, G.Y. et al.: Kauch. Rez., 26, 28 (1967); Sofuni, T. et al.: Mutat. res. Gen. Toxicol. Test., 24, 175 (1990);<br></p>

<p>Applications 3-ETHOXY-2-CYCLOHEXEN-1-ONE (cas# 5323-87-5) is a useful research chemical.<br></p>

<p>Applications 1,3-Diacetoxy-2-(acetoxymethoxy)propane is a compound involved in the synthesis of Ganciclovir (G235000), an antiviral nucleoside analog structurally related to Acyclovir (A192400).<br>References Halloran, P.J. and Fenton, R.G.: Cancer Res., 58, 3855 (1998), Rubsam, L.Z., et al.: Cancer Res., 59, 669 (1999), Yamasaki, H., et al.: C.R. Acad. Sci. III, 322, 151 (1999)<br></p>

<p>Applications 4,4'-Dimethoxystilbene is an intermediate in the synthesis of nonsteroidal, selective estrogen receptor modulator (SERM), Raloxifene (R100000).<br>References Liu, H., et al.: Chem. Res. Toxicol., 18, 162 (2005); Chen, Z., et al.: J. Org. Chem., 65, 8811 (2000);<br></p>

<p>Applications Methyl (1R,4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Ester is used in the discovery of a potent, selective and orally bioavailable dual CCR2 and CCR5 antagonist.<br>References Zheng, C., et al.: Bioorg. Med. Chem. Lett., 21, 1442-1446 (2011)<br></p>

<p>Applications 3,4-Dimethoxytoluene is a volatile flavor compound found is many substances such as boiled buckwheat flour, wild rice grain and tar of hickory wood smoke.<br>References Yajima, I., et. al.: Agr. Bio. Chem. 47, 729 (1983); Withycombe, D.A., et. al.: J. Agr. Food Chem., 26, 816 (1978); Hruza, D.E., et. al.: J. Agr. Food chem., 22, 123 (1974)<br></p>

<p>Stability Hygroscopic<br>Applications [3-(Ethoxycarbonyl)propyl]triphenylphosphonium Bromide is a reactant used in the preparation of maresin 1, a potent anti-inflammatory and pro-resolving lipid mediator.<br>References Tungen, J.E., et. al.: Tetrahedron Lett., 56, 1843 (2015)<br></p>

<p>Applications N-ethyl-3,4-dimethoxyaniline (cas# 32953-13-2) is a useful research chemical.<br></p>

<p>Applications [4-(Difluoromethoxy)phenyl]hydrazine is used as a reagent in the synthesis of dihydropyrazolopyridinones as functionally selective benzodiazepine binding site ligands on the GABAA receptor.<br>References Mitchinson, A., et al.: Bioorg. Med. Chem. Lett., 14, 3441 (2004)<br></p>

<p>Applications Tetramethoxypropane is a useful synthetic intermediate. It can be used to synthesize various compounds such as diiodonoradamantane and Salicylates[e.g. Salsalate(S095700)].<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ioannou, S., et al.: Tetrahedron Lett., 51, 2671 (2010); Sher, M., et al.: J. Org. Chem., 72, 6284 (2007)<br></p>