Organoboranes

Applications [3-[(Trimethylsilyl)oxy]-2-cyclohexen-1-yl]-benzene (cas# 108643-81-8) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications N-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).
References Takano, R. et al.: J. Carb. Chem., 14, 885 (1995); Rao, K. et al.: Synth. Comm., 37, 2275 (2007);

Applications (2-Cyclobuten-1-yldimethylsilyl)benzene is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

Applications (1-Ethoxycyclopropoxy)trimethylsilane used as a reactant in the synthesis of di-, tri- and tetracyclopropylhydrazines. Also used as reagent in the synthesis of g elsemoxonine which is found in gelsemium plant species that is used in traditional asian medicine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shestakov, A., et al.: Chem. Commun., 52, 2398 (2016); Diethelm, S., et al.: J. Am. Chem. Soc., 137, 6084 (2015);

Applications Ethyl [(tert-Butyldimethylsilyl)oxy]acetate (cas# 67226-78-2) is a compound useful in organic synthesis.

Applications 3-[[(1,1-Dimethylethyl)diphenylsilyl]oxy]-1,2-propanediol is an intermediate in the synthesis of 1,2-Dioleoyl-rac-glycerol (D482175), which is an analog of 1,3-Dioleoylglycerol (D484210) which is used in the synthesis of amphiphilic gadolinium complexes as MRI contrast agents.
References Accardo, A., et. al.: J. Mater. Chem. B., 1, 617 (2013)

Stability Volatile
Applications Hexamethyldisilane is an organic silylating and disilylating reagent. It is also a useful reagent for reductive coupling, reductive deuteration, aroylarylation, carbosilylation, insertion, deuteration and dimerization reactions.
References Xiao, G., et al.: Tetrahedron Lett., 59, 1836 (2018); Lu, A., et al.: Angew. Chem. Int. Ed., 57, 3233 (2018); Deb, M., et al.: New J. Chem., 41, 14528 (2017); Hiyama, T., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2010)

Applications Trimethylboroxin is used in a diverse array of areas, including as a polymerization additive. Trimethylboroxin is also used in the preparation of CBS catalysts for asymmetric reductions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gilmore, N., et al.: Tetrahedron Asy., 14, 2115 (2003); Najera, C., et al.: Adv. Synth. Catal., 346, 1798 (2004);

Stability Moisture Sensitive
Applications Chlorotriethoxysilane (cas# 4667-99-6) is a useful research chemical.

Applications 1,3-Bis(tert-Butyldimethylsiloxy)-2-propanol is an intermediate in the synthesis of 2-Linoleoyl-rac-glycerol (L467960), which is a atty acid monoglycerides in vegetable oils with medium unsaturation.
References Compton, D., et al.: J. Pharmacol. Exp. Ther., 277, 586 (1996), Devane, W., et al.: Science, 258, 1946 (1992),

Applications 1,​2-​Bis(trimethylsiloxy)​ethane is an organic reagent, used in the preparation of nonracemic hexahydrofurapyranol which acts as a high-affinity ligand for HIV-1 protease inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ghosh, A. et al.: Tetra. Lett., 58, 3230 (2017)

Applications Tetrabutylammonium Borohydride is a strong reducing agent used in the synthesis of hyperbranched polyglycerol grafting on the surface of silica-coated nanoparticles.
References Panja, P. et al.: ACS Sust. Chem. Eng., 5, 4879 (2017);

Applications N-(Methoxymethyl)-N-[(trimethylsilyl)methyl]benzenemethanamine is used in the synthesis of pyrrolidine derivatives as novel sodium channel blockers used to treat ischemic related ailments.
References Seki, M. et al.: Bioorg. Med. Chem. Lett., 23, 4230 (2013);

Stability Hygroscopic, Light-sensitive
Applications Triphenylmethylium Tetrafluoroborate is reagent used in organic synthesis such as the direct synthesis of 1,1-diphenyl-3-arylindanes.
References Surapanich, N. et al.: Synlett., 27, 2689 (2016);

Applications rac 1-O-Trimethylsilyl 3-Chloro-1,2-propanediol (cas# 1246820-26-7) is a compound useful in organic synthesis.

Applications Allenylboronic acid pinacol ester

Applications N,N-Diethyl(trimethylsilyl)amine is a chemical reagent with wide application in organic chemistry. Used in stereospecific addition reactions as well as in SN2 nucleophilic substitutions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bassindale, A. et al.: J. Organometal. Chem., 667, 66 (2003); Hagiwara, H. et al.: J. Chem. Soc., Perk Trans., 3, 316 (2002);

Applications 3-(Dimethylphenylsilyl)-cyclobutanone is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

Applications 3-[(tert-Butyldimethylsilyl)oxy]-1-propanol (cas# 73842-99-6) is a compound useful in organic synthesis.

Stability Moisture Sensitive and Hygroscopic
Applications Triethylsilyl Trifluoromethanesulfonate is a reagent used in the synthesis of pharmaceuticals such as cocosolide, an immunosuppressive agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gunasekera, S. et al.: Chem. Eur. J., 22, 8158 (2016);

Applications Tetraethylammonium Tetrafluoroborate is used in the preparation of some organic salts of fluoboric acids.
References Wilke-D., et al.: Ber. Dtsch Chem. Ges.; 60B, 115 (1927)

Applications Hydrogen Tetrafluoroborate(1-) is a useful building block for organic synthesis.
References Ohkuma, T., et al.: Journal of the American Chemical Society., 218, 8724 (2006)

Applications Tris(trimethylsilyl)silane) is used in the synthesis of silated alkenes and alkynes. Also used in the preparation of fused quinolines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kopping, B.et al.: J. Org. Chem., 57, 3994 (1992); Du, W. et al.: Org. Lett., 5, 1765 (2003);

Stability Moisture Sensitive
Applications Tert-Butyldimethylsilyl Trifluoromethanesulfonate is a highly reactive silylating agent and lewis acid capable of converting primary, secondary and tertiary alcohols to their respectctive TBDMS. Tert-Butyldimethylsilyl Trifluoromethanesulfonate is also used to covert ketones and lactones into their enol silyl ethers.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hua, D.H. et al.: e-ROS Encyc. Reag. Org. Synth., No pp. given (2001); Suzuki, T. et al.: Synthesis, 4, 555 (2001);

Applications Triisopropyl Borate is a borate ester used in Suzuki couplings.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wolfe, J. et al.: J. Am. Chem. Soc., 121, 9550 (1999); Darses, S. et al.: Eur. j. Org. Chem., 8, 1875

Applications TRIPHENYLSILANE (cas# 789-25-3) is a useful research chemical.

Ethyl boronic acid is a monobasic organic acid that is an important component of the pharmacophore of many antibiotics. It has been shown to have an inhibitory effect on β-lactamase and s. epidermidis. Ethyl boronic acid also inhibits the growth of p. aeruginosa, which is resistant to β-lactams, by binding to the enzyme's active site and preventing it from hydrolyzing penicillin-type antibiotics. This molecule is synthesized from ethyl chloride in a two-step process that involves asymmetric synthesis that results in high melting points and natural compounds with health effects.

(R)-Benzyl-2-[4-(trifluoromethyl)phenyl]-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazolium Tetrafluoroborate is a bactericide that inhibits the production of proteins necessary for cellular growth. It has been shown to inhibit the growth of bacteria such as E. coli in vitro and in animal models. The effective dose for this drug is not known at this time.

3-Carboxyphenylboronic acid is a natural compound that is used in the treatment of tumors. It is also used as a starting material for the synthesis of other compounds, such as 3-carboxyphenylboronic acid and 3-carboxyphenylboronic acid hydrochloride. 3-Carboxyphenylboronic acid has been shown to activate signal pathways involved in tumor growth, survival, and metastasis. This drug has low bioavailability and can be excreted through urine or human serum. 3-Carboxyphenylboronic acid contains a pyrazole ring with ester linkages. Hydrogen bonding interactions are also present between this molecule and dopamine, which may account for its antitumor activity.

2-(Dimethylphenylsilyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a chiral ligand that can be used in asymmetric synthesis. It has been shown to be effective in the palladium-catalyzed cross-coupling of aldehydes with organoboronic acids. 2-(Dimethylphenylsilyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane inhibits the formation of an undesired enolate by binding to the silicon atom and sterically preventing nucleophilic attack at this site. This ligand is also selective for anions with a single negative charge such as chloride and bromide.