Amides

<p>4-Sulfonamidephenylhydrazine HCl is a sulfonamide that inhibits the enzyme Cox-2, which is involved in inflammation. It also has anti-inflammatory activity and has been shown to inhibit the growth of fungi. 4-Sulfonamidephenylhydrazine HCl is an antifungal agent used for the treatment of dermatophytic infections such as tinea pedis and tinea cruris. The chemical structure of 4-Sulfonamidephenylhydrazine HCl consists of a methyl sulfone group linked with a pyrazole ring and a hydrazine hydrate group. The carbonic acid moiety in this compound stabilizes the pyrazole ring by forming hydrogen bonds with the nitrogen atom and oxygen atom on either side of it. This allows for the formation of two resonance structures to be maintained, which make it more stable than other similar compounds without this moiety.</p>

<p>Hydroxyflutamide is an anti-androgen drug that belongs to the group of nonsteroidal anti-androgens. It has been shown to bind to the androgen receptor with high affinity and inhibit the growth of cancer cells in vitro. Hydroxyflutamide also has a strong antitumor response in vivo, which is due to its ability to inhibit cellular proliferation by binding to DNA polymerase during replication. The drug may also have some activity as an antineoplastic agent because it inhibits the growth of prostate cancer cells. However, hydroxyflutamide has never been tested on humans or animals, so its effects are unknown.</p>

<p>Alkylating agent; anti-cancer agent</p>

<p>N-Propyl-N-(2,3-dihydroxypropyl)perfluoro-n-octylsulfonamide is a fine chemical that can be used as a reagent and speciality chemical. It is a versatile building block that can react with other compounds to produce new products. The compound is a complex compound that has been shown to have high quality in the laboratory.</p>

<p>2-Phenylbenzamide (2PB) is a drug that belongs to the class of anthelmintics. It binds to the nicotinic acetylcholine receptor and inhibits the release of acetylcholine at neuromuscular junctions, leading to paralysis and death of the parasite. 2PB also has been shown to have anti-inflammatory properties in mice with colitis, which may be due to its ability to inhibit prostaglandin synthesis. The molecular docking analysis showed that 2PB binds covalently with nitro-containing molecules, such as nitrosamines, which are found in cigarette smoke and are known carcinogens. This binding may contribute to the development of cancer through inhibition of DNA repair mechanisms.</p>

<p>N-Methyl-N-trimethylsilylacetamide is a bifunctional amide that can react with an electrophile, such as hexane, to form an N-methylated product. The amide group of the molecule can also be deprotonated by a strong base to form an enolate, which can then react with a nucleophile. The NMR spectra of this compound show that it has a multinuclear structure and contains two tautomers. It is used in analytical chemistry for sample preparation, chromatographic science for reaction intermediates, and chemical study for its reactivity.</p>

<p>4-Nitrobenzamide is a chemical substance that belongs to the class of nitrobenzamides. It is used as an intermediate in the synthesis of other substances, such as pharmaceuticals, herbicides, and pesticides. 4-Nitrobenzamide was first synthesized in 1894 by hydrogenating nitrobenzoic acid with hydrogen chloride in the presence of phosphorus pentachloride. The reaction vessel for this process should be made of glass or porcelain due to the corrosive nature of hydrogen chloride gas. The kinetics for this reaction were studied using concentration-response curves on rats and mice at different concentrations. Acute toxicities observed include respiratory distress and death in rats and convulsions and death in mice.<br>4-Nitrobenzamide is also toxic to bacteria, which can be seen by its effect on Staphylococcus aureus (strain ATCC 25923). This strain had a 50% survival rate after exposure</p>

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<p>2,3-Diaminobenzamide is a synthetic aromatic compound that is used as a radiation stabilizer. It is also an effective antimicrobial agent with reactive properties against bacteria and fungi. 2,3-Diaminobenzamide has been shown to have anti-cancer properties and can be used to treat inflammatory diseases such as rheumatoid arthritis or ulcerative colitis. The intramolecular hydrogen bond between the amide group and the benzene ring in 2,3-diaminobenzamide contributes to its stability and biological activity.</p>

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<p>Labetalol is a β-blocker that is used to treat high blood pressure. Labetalol hydrochloride, the active form of labetalol, is a white, crystalline compound with a melting point of 200 °C. It is soluble in water and has an acidic pH of 2. Labetalol hydrochloride is synthesized by reacting methylbenzene with labetalol, which forms intermediates such as methyl 4-hydroxylbenzoate and methyl 3-hydroxylbenzoate in the process. The intermediates are then recrystallized to form the final product. Labetalol hydrochloride undergoes thermal analysis using thermogravimetry, calorimetry, and residue analysis to determine its purity. This product also undergoes carbonaceous and oxidative analysis by GC-MS for quality control purposes.</p>

<p>4-Chloro-3,5-dinitrobenzamide is a bifunctional molecule that contains a chlorine atom. It has been found to react with dipolar solutes as well as vicinal dioxan arylation. The nucleophilic amide group is also labile and can be hydrolyzed by strong acids or bases. The electron lone pair of the chlorine atom in 4-chloro-3,5-dinitrobenzamide can be used for electrophilic substitution reactions with aromatic rings or amines. This molecule has been found to undergo an arylation reaction with imidazole in the presence of dioxan solvent at room temperature.</p>

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<p>2-Hydroxysalicylamide is a low-energy, small molecule that has shown to be an effective inhibitor of serine proteases. It binds to the active site of the protease, blocking catalysis and inhibiting the growth of cancer cells. 2-Hydroxysalicylamide has been shown to inhibit the transcriptional regulation of pro-inflammatory genes in a patterning assay and it inhibits tumor growth in a pain model. This drug also suppresses the expression of suppressor genes and can be used as an analgesic without causing side effects.<br>2-Hydroxysalicylamide is also a polarizer for tissues, meaning that it preferentially accumulates in tissues with high water content such as breast tissue. This property has been shown to be useful for imaging cancerous tumors.</p>

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<p>Cyclotheonamide A is a cyclopeptide, which is a type of secondary metabolite composed of non-standard amino acids arranged in a cyclic structure. It is naturally sourced from marine sponges, particularly Theonella sp., which are known for their rich and diverse repertoire of bioactive compounds. Cyclotheonamide A functions through the inhibition of serine proteases, a class of enzymes that play a significant role in numerous biological processes, including digestion, immune response, and blood coagulation.</p>

<p>2,4-Dichloropyrimidine-5-carboxamide is a 2,4-dichloropyrimidine derivative. It is an intermediate in the synthesis of other compounds, and can be used as a building block in the synthesis of complex compounds. It is a versatile building block that can be used to make many different products. This chemical has been shown to have high quality and is useful as a research reagent or speciality chemical. 2,4-Dichloropyrimidine-5-carboxamide is also a useful intermediate for reactions involving nucleophilic substitution reactions and can serve as a scaffold for organic synthesis.</p>

<p>2-Cyanoacetamide is an organic compound that is used in pharmaceutical preparations. It reacts with malonic acid to form a dioxime, which is a precursor of various drugs. The optimum concentration for the reaction to occur is at 10% (w/v). The reaction mechanism has not been fully elucidated and it involves the transfer of nitrogen from an amide group to a carbonyl group. 2-Cyanoacetamide has shown anti-angiogenic effects in mice by inhibiting the expression of Mcl-1 protein, which is involved in the regulation of apoptosis and inflammation. This drug also has biological functions as a precursor for dopamine, which helps regulate motor and cognitive functions.</p>

4-Hydroperoxycyclophosphamide (4-HPPC) is a cytotoxic agent with anti-cancer properties. It is a prodrug that is converted to 4-hydroxycyclophosphamide, the active form of the drug, by hydrolases in cells. The cytotoxicity of 4-HPPC has been demonstrated using a model system of human erythrocytes and HL60 cells. This drug also has an effect on tumor growth and metastasis, as well as on bowel disease. Rats treated with 4-HPPC showed decreased levels of blood glucose, increased glutathione peroxidase activity, and a decrease in the number of colonic tumors after only one dose. The low-dose group had improved mitochondrial membrane potential and an increase in cell factor receptor activity. These results indicate that 4-HPPC may be a useful anti-cancer compound for treating various types of cancer including colon cancer.

<p>DL-Alanine-beta-naphthylamide hydrochloride is a fine chemical that is used as a building block for other compounds. It can be used in the synthesis of complex compounds and as a reagent to synthesize speciality chemicals and research chemicals. DL-Alanine-beta-naphthylamide hydrochloride is also a versatile building block that can be used as an intermediate in organic reactions or as a reaction component. This compound has CAS No. 74144-49-3 and is soluble in water.</p>

<p>3-Hydroxybenzamide is a potent inhibitor of the enzyme synthetase and has been shown to inhibit the synthesis of adenosine diphosphate (ADP) ribose. It has been shown to have potent inhibitory activity against the enzyme in both solid and liquid phases. 3-Hydroxybenzamide binds to the carbonyl group of ADP ribose, which prevents it from binding to ATP. This inhibition of the synthesis of nucleotides limits cell proliferation by preventing DNA replication and protein synthesis. 3-Hydroxybenzamide has also been shown to inhibit the growth of mouse leukemia cells in vitro, as well as inhibiting l1210 murine leukemia cells grown in vivo. The mechanism for this inhibition is not yet known, but may be due to its ability to bind with hydrogen bonds or intramolecular hydrogen bonds. 3-Hydroxybenzamide also has a skeleton that can be synthesized asymmetrically by using a chiral</p>

<p>N,N'-Dimethyl-3,3'-dithiodipropionamide (DTDPA) is a strong oxidizing agent that is used as a catalyst in organic synthesis. It can be used to convert xylene and benzene into products that are less toxic and more easily removed from the environment. DTDPA can also be used to remove 2-methyl-4-isothiazolin-3-one, chloroform, and other pollutants from water. DTDPA has been shown to react with hydrogen peroxide or hydrochloric acid to produce oxygen gas and chlorine, which is an effective disinfectant against bacteria such as Staphylococcus aureus or Pseudomonas aeruginosa. This chemical also reacts with toluene or chloroform to produce peroxides which have been shown to have an anti-inflammatory effect on cells.</p>

<p>1-Methyl-1,4-dihydronicotinamide (1MDNA) is a flavine adenine dinucleotide analog that has been shown to be a potent inhibitor of the enzyme catalase. 1MDNA binds to the active site of the enzyme and prevents hydrogen peroxide from being converted into water and oxygen. This inhibition slows down or stops the reaction, which leads to reduced production of reactive oxygen species. 1MDNA inhibits other enzymes in a similar manner, including transferases and kinases. The kinetic properties of 1MDNA have been studied by performing kinetic studies on model systems at different temperatures. X-ray crystal structures have also been obtained for 1MDNA bound to catalase and ferredoxin.</p>

<p>Deacetamide linezolid phthalimide is a chemical compound that is used as an intermediate in the synthesis of a variety of pharmaceuticals. It has been shown to be useful for the production of a number of compounds, including antibiotics, anti-inflammatory agents, and anticancer drugs. The substance has been shown to be effective in the treatment of bacterial infections and was first discovered in research chemicals. This compound also has a high quality and is used as a reagent for chemical reactions.</p>

<p>Acetyl-L-tyrosine amide is an analog of L-tyrosine that is used as an active substance in the field of uv absorption. Acetyl-L-tyrosine amide reacts with sodium hydroxide to form a soluble salt, which has been shown to have binding constants that are comparable to those of human serum. This compound also has fluorescence properties and can be used for the determination of neutral pH. The reaction products formed between acetyl-L-tyrosine amide and sodium hydroxide are hydrolyzed by acids and yield a molecule with rotameric properties. These rotameric properties can be modeled using a protein model without affecting the stability or function of the protein.</p>

<p>Non-steroidal androgen receptor antagonist</p>

<p>2,3-Dichlorobenzamide is a herbicide with a stable structure. It has been shown to be effective against the weed species Agropyron repens and other grasses that grow in wetland conditions. 2,3-Dichlorobenzamide inhibits the growth of these plants by causing chlorosis, which is characterized by yellowing of leaves. 2,3-Dichlorobenzamide is toxic to aquatic organisms and can cause pollution in water systems. The molecular electrostatic potential of 2,3-Dichlorobenzamide has been studied using computer models and the parameters have been used to predict its toxicity to various tissues such as nerves or liver cells.</p>

<p>Methylthioacetic acid is a weak organic acid that is used as an ophthalmic drug. When methylthioacetic acid is activated, intramolecular hydrogen bonds form between the methylthiosulfonate ion and the nitrate ion. This process requires spin resonance to take place, which can be explained by the functional theory of kinetics. The reaction of methylthioacetic acid with nitrate ions to form methylthiosulfonate ions has been shown to be rapid and reversible in both dry weight and wet weight experiments. The alkylation of methylthioacetic acid with ethyl bromoacetate has been shown to produce thermochemically stable imine and phosphate ions.</p>

<p>2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride (BPDC) is a synthetic compound that is used as an analytical reagent and a model system for oxidative injury. It has significant cytotoxicity on human cells in cell culture. BPDC induces oxidative damage to proteins and DNA by increasing the production of reactive oxygen species such as hydrogen peroxide, superoxide, and hydroxyl radicals. The mechanism of action is not well understood but may be due to Toll-like receptor signalling pathways. This compound has been shown to inhibit the activity of antioxidant enzymes such as glutathione peroxidase and catalase. It also inhibits the activity of proinflammatory cytokines such as IL-6 and IL-8. BPDC is being investigated for its potential use in bowel disease treatment.</p>

<p>2,6-Dichlorobenzamide is a chemical compound that belongs to the group of organochlorine compounds. It is soluble in water and has been shown to be an effective treatment for metal contamination in groundwater. 2,6-Dichlorobenzamide reacts with metal ions at the surface of cells by forming an insoluble metal chloride complex that accumulates inside the cell and leads to cell death. 2,6-Dichlorobenzamide has been shown to be toxic to bacteria, particularly gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis. This compound also binds to bacterial membrane lipids with high affinity constants. This activity may be due to its ability to form lipid hydroperoxides and free radicals.</p>

<p>Trifluoromethanesulfonamide is a strong acid that has been shown to inhibit the proteolytic activity of human secretase. It binds to a specific site on the enzyme and prevents it from cleaving the substrate. This inhibition slows down the progression of Alzheimer's disease, Parkinson's disease, and other related disorders. Trifluoromethanesulfonamide has also been shown to bind to metal hydroxides, such as iron hydroxide, which may be due to its ability to form hydrogen bonds with these metals. Structural analysis reveals that trifluoromethanesulfonamide contains a pyrazole ring and two chlorine atoms, one in the para position and one in the meta position.</p>

<p>2-Chloro-N,N-diphenylacetamide is a functional theory that has been shown to have antimicrobial activity against mammalian cells. It is an acetamide derivative with a formyl group and two chloro substituents. 2-Chloro-N,N-diphenylacetamide inhibits the growth of Mycobacterium tuberculosis by binding to the ribosomal protein P0, which inhibits the production of proteins vital for cell division. This drug also has antifungal properties, inhibiting the synthesis of ergosterol in filamentous fungi such as Candida albicans.<br>2-Chloro-N,N-diphenylacetamide is also known to inhibit the growth of other bacteria by binding to their ribosomes and interfering with protein synthesis. This drug may also be active against viruses due to its ability to bind chloride ions.</p>

<p>N-Chloro-4-toluenesulfonamide sodium (NCTS) is a disinfectant that is used to treat wastewater and as a preservative for water. It has been shown to be effective against bacteria, fungi, and viruses. NCTS is an antimicrobial agent that reacts with the matrix in which it is applied to form chloramines-T (NHClO). The chloramines-T inhibits the activity of enzymes such as those involved in DNA synthesis and protein synthesis. This reaction also generates an electric current due to the redox potentials of the reactants. The presence of aziridines in NCTS leads to crosslinking between proteins, which enhances its effectiveness as a disinfectant.<br>NCTS has been shown to have no adverse effects on human erythrocytes or DNA when used at concentrations up to 100 µg/mL.</p>

<p>5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide is an experimental compound that is used in the industrial preparation of pharmaceuticals and agricultural chemicals. It has a molecular weight of 191.14 g/mol. The crystallization process involves the use of ethanol to create supersaturation and then cooling to induce crystallization. This compound can be synthesized by an iodination reaction with x-ray irradiation at low temperatures.</p>

<p>N,O-Bis(trimethylsilyl) acetamide is a protein that is used as a reagent for the detection of integrin receptors. It can be used to identify human immunoglobulin and human serum proteins. This compound has been shown to be pluripotent in cells, which means that it can differentiate into any type of cell. N,O-Bis(trimethylsilyl) acetamide has been shown to have surfactant properties and can be used as an alternative in toxicity studies. This compound has been shown to be toxic to bowel disease cells when tested with a dose of 3mg/mL. The disulfide bond within this molecule may be important for its biological activity. Synchronous fluorescence spectroscopy and plasma mass spectrometry are two methods that have been used to study the structure of this molecule. Electrochemical impedance spectroscopy is another method that has been used in the structural analysis of this molecule.</p>

<p>This is a high quality reagent, complex compound, useful intermediate, and fine chemical. It is also a useful scaffold and can be used as a reaction component in the synthesis of speciality chemicals. The CAS number for this compound is 3873-79-8. <br>[[Category:Chemical Compounds]]</p>

<p>N-[(4-Amino-2-methylpyrimidin-5-yl)methyl]formamide (NAMPT) is a triazolo compound that inhibits the ATP binding cassette transporter and blocks the uptake of uridine and pyrimidine compounds. It also inhibits inorganic pyrophosphatase, which is an enzyme that catalyzes the hydrolysis of pyrophosphate to inorganic phosphate. NAMPT has been shown to be a substrate for hypochlorous acid production in neutrophils, suggesting it may play a role in the regulation of oxidative stress. Chemical biology studies have demonstrated that NAMPT plays a physiological function as an intermediate in vitamin B1 biosynthesis.</p>

<p>N-Methyl-4-pyridone-3-carboxamide is a nonnutritive sweetener that has been shown to have no effect on peroxisome proliferation. It also had no effect on the levels of fatty acids in rat cardiomyocytes and did not affect uv absorption. N-Methyl-4-pyridone-3-carboxamide binds to the receptor α subunit of the taste receptor and inhibits adenosine uptake, which may be responsible for its effects on depression. This compound also alters energy metabolism by inhibiting mitochondrial ATP production and glycolysis.</p>

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<p>2-(3-Hydroxyphenyl)acetamide (2HPA) is a sulfonamidochrysoidine compound with analgesic, antipyretic and anti-inflammatory effects. It is used in the treatment of gout, rheumatoid arthritis, osteoarthritis and other inflammatory diseases. 2HPA has been shown to be effective in the treatment of pain following dental surgery. 2HPA is also used as a marker for dietary intake of sulfate and may be a useful indicator for determining the effect of changes in diet on urinary excretion rates. The elimination half-life of 2HPA is approximately 3 hours in humans. This drug can be detected in urine samples from humans within 24 hours after ingestion at concentrations that are proportional to dose.</p>

<p>Dopamine (D2) receptor antagonist; 5-HT4 serotonin receptor agonist</p>

<p>Voltage-gated sodium channel blocker</p>

<p>N-Methyl-N-vinylacetamide is a colorless liquid with a boiling point of 105.6°C. It is produced by the reaction of acetamide and vinyl chloride in the presence of hydrochloric acid, glycol ether, and methyl ethyl ketone. The viscosity of this compound is low, which makes it an ideal solvent for paints and coatings. N-Methyl-N-vinylacetamide also has genetic damaging effects and can cause mutations in bacteria that are exposed to this compound in high concentrations. This product has an unusual chemical structure due to its hydrogen bonding interactions.br&gt;br&gt;<br>br&gt;br&gt;<br>Hydrogen bonds are weak intermolecular forces between polar molecules, such as water or alcohols, that are formed by the attraction between a partially positive hydrogen atom on one molecule and the negative end of another nearby molecule. Hydrogen bonds stabilize certain molecular structures because they provide partial shielding from electrostatic interactions with</p>

<p>2-(5-Bromo-1H-indol-3-yl)acetamide is a high quality, reagent, complex compound, useful intermediate and fine chemical. It is also a useful scaffold or building block for the synthesis of speciality chemicals. 2-(5-Bromo-1H-indol-3-yl)acetamide is used in research and development as a versatile building block for the synthesis of new compounds. The CAS number for this compound is 196081-79-5.</p>

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