Amides

<p>Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a peptide that was generated by incubating β-amyloid with the protease papain. This peptide has been shown to induce population and biochemical changes in cells, including focusing of β-amyloid aggregates. It also induces reactive oxygen species and promotes extracellular protofibril formation. Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a conjugate of acetylated lysine residues and amyloid β-protein that can be used as an anti-amyloid therapeutic. The peptide is characterized by dichroism spectroscopy, which has revealed its specific binding to the fibrils' surface.</p>

<p>Tenofovir alafenamide (free base) is a prodrug of tenofovir with action on viral reverse transcriptase to block replication and is used for treating HIV/AIDS and chronic hepatitis B with improved safety profile.</p>

<p>Please enquire for more information about Dnp-Pro-TNF-alpha (71-82) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (Phe1,Ser2,Tyr6)-PAR-1 (1-6) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Dynorphin A (1-11) amide trifluoroacetate salt is a modified form of the opioid peptide dynorphin, which is a natural ligand for kappa-opioid receptors. It has affinity for the surface receptors and can be used to study the modifications that occur in cell function. Dynorphin A (1-11) amide trifluoroacetate salt has been shown to decrease cell function when it interacts with these surface receptors, which are found in brain homogenates and other tissues. Dynorphin A (1-11) amide trifluoroacetate salt also has an effect on brain cells, which may be due to its ability to alter conformational changes in proteins by binding to them. This can lead to alterations in the structure of certain enzymes or receptor proteins.</p>

<p>6-Aminopicolinamide is a metabolite of nicotinamide, which can be found in the urine of humans and animals. 6-Aminopicolinamide has been shown to have anti-leukemic activity against experimental leukemias in animals. The mechanism of action is not well understood but may involve inhibition of nucleotide synthesis or the inhibition of dehydrogenase activity. Clinical trials are underway to determine its efficacy as an anti-tumor agent.</p>

<p>L-Glutamic acid alpha-amide is an ester hydrochloride that is a tissue culture amide. It is a cyclic peptide analog and a hydroxyl group. L-glutamic acid alpha-amide has been shown to inhibit the inflammatory response in the bowel disease, Crohn's disease, by blocking the toll-like receptor 4 and 5. This drug also inhibits protein synthesis, which may be due to its ability to bind to fatty acids, thereby inhibiting the production of proteins vital for cell division.</p>

<p>Adamantane is a cyclic hydrocarbon with 18 carbon atoms. It is a colorless, crystalline compound that is soluble in organic solvents. Adamantane has been used as an anti-influenza drug for the treatment of pandemic influenza. Adamantane binds to the virus and inhibits its ability to bind to the host cell surface receptor, preventing viral entry into the cell. Adamantane has been shown to be effective against both influenza A and B viruses in animal studies. Adamantane also has an inhibitory effect on amine metabolism and aryl halide reactions, which may be due to its hydrogen bond forming abilities.</p>

<p>Sodium dicyanamide is a diphenyl ether that has been shown to be effective in the treatment of polycystic ovarian syndrome. It binds to picolinic acid, which is a cofactor for the enzyme phenylalanine hydroxylase, and inhibits the production of tyrosine. This leads to an increase in the levels of luteinizing hormone and follicle-stimulating hormone, which helps ovulation. Sodium dicyanamide also interacts with hydrogen bond interactions and chelate ligands. The reaction mechanism of this compound is not well understood, but it is known that it can react with oxygen at high temperatures.</p>

<p>Please enquire for more information about Acetyl-Neurotrophin Receptor (368-381) amide (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Antho-RPamide III·HCl Pyr-Val-Lys-Leu-Tyr-Arg-Pro-NH2·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Met-Enkephalin-Arg-Phe amide H-Tyr-Gly-Gly-Phe-Met-Arg-Phe is a subunit of the endogenous opioid peptide Met-enkephalin. It is a proteolytic cleavage product of proenkephalin A and is also known as Tyr2, Phe2, or Arg6. Met-enkephalin has been shown to participate in signal transduction pathways that regulate blood pressure and exocrine secretion. Metenkephalin is an amide containing two cysteine residues with a hydrophobic side chain, which can bind metal ions such as calcium ions. Metenkephalin binds to the membrane of cells, altering membrane potential and naloxone binding sites.<br>Met enkephalin has been shown to be involved in serotonin release from platelets and inhibition of serotonin uptake by platelets.</p>

<p>Please enquire for more information about (D-Trp6)-LHRH (1-6) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Big Endothelin-3 (22-41) amide (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Salicylamide is a drug that is used as an analgesic, antipyretic, and anti-inflammatory agent. It is also used to treat bowel disease, including ulcerative colitis and Crohn's disease. Salicylamide has been shown to inhibit the activity of enzymes such as cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), which are responsible for the production of inflammatory mediators. Salicylamide also inhibits copper chloride induced synchronous fluorescence in rat colon cells. Salicylamide also binds to human serum albumin and other nitrogen atoms, which can be measured using chemiluminescence methods. Salicylamide may also have properties that make it useful for the detection of cancerous tumors in the colon. Salicylamide can be detected using electrochemical impedance spectroscopy by measuring its resistance at different frequencies when a voltage is applied across a cell containing sal</p>

<p>Nazumamide A is a cyclic peptide with inhibitory activity against serine proteases. It binds to the active site of thrombin and inhibits its action, thereby inhibiting the fibrinogen degradation in blood. Nazumamide A is also found to have neuroprotective properties, which may be due to its ability to inhibit nitric oxide production by binding to the enzyme nitric oxide synthase. It has been shown to have anti-inflammatory activities and can be used for the treatment of inflammation-associated diseases such as asthma and arthritis. Nazumamide A is a nonribosomal peptide that does not require any cofactors for synthesis.</p>

<p>Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt is a peptide that is used as an analgesic and antipyretic drug. It is a synthetic form of endogenous enkephalins, which are natural pain relievers. The chemical stability of Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt makes it an effective drug for chronic use, and it has been shown to have a low side effect profile. This compound also has been shown to block the synthesis of histamine in vivo, but its bioavailability in vivo is not high due to its rapid degradation by proteases.</p>

<p>Please enquire for more information about (D-Phe5,Cys6·11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (D-Trp6)-LHR including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Chloroacetamide is a quaternary ammonium compound that is used as an intermediate in the synthesis of other organic compounds. It has been reported to have anticancer activity and has been studied for use as a herbicide in agriculture. The vibrational, turbidimetric method, amide, and sample preparation are all instrumental in determining the reaction mechanism of 2-chloroacetamide. This molecule has also been studied using FT-IR spectroscopy and molecular modelling techniques. The hydrogen bond is integral to its optical properties and can be determined by nmr spectra.</p>