6-membered Rings

Applications 2-amino-3-hydroxy-3-phenylpropanoic acid (cas# 7695-56-9) is a useful research chemical.

Applications 4-phenyl-2,3-dihydroquinazolin-2-one (cas# 23441-75-0) is a useful research chemical.

Applications N-[(2,4-Difluorophenyl)methylene]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D450850), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.
References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)

Applications 5-Benzyl Hydantoin (cas# 3530-82-3) is a compound useful in organic synthesis.
References Suzuki, S., et al.: J. Bacteriol., 188, 3329 (2006), Jiang, M., et al.: Enz. Microb. Technol., 41, 407 (2007),

Applications (2-Isocyanoethyl)-benzene is a useful synthetic intermediate. It is a reagent used in Ugi reactions to synthesize various compounds such as tetrazole and bisamide.
References Zhao, T., et al.: Org. Lett., 15, 639 (2013); Brockmeyer, F., et al.: Helv. Chim. Acta., 95, 1857 (2012)

Applications Methyl 4-Chlorobenzoate is a reactant used in the synthesis of ataxia-telangiectasia mutated (ATM) kinase, a target for novel radiosensitizing agents. As well, used as a reactant in the synthesis of aminopyridine functionalized polyacrylonitrile fibers.
References Min, J. et al.: J. Med. Chem., 59, 559 (2016);

Applications (3,5-Dimethoxyphenyl)acetonitrile (cas# 13388-75-5) is a compound useful in organic synthesis.

Applications Dibenzoylmethane is a compound known to inhibit tumorigenesis in mice.
References Lin, C. C., et al.: Cancer Lett., 168, 125 (2001)

Applications 2,4,6-Triisopropylbenzenesulfonyl Azide is a useful synthetic intermediate. It is used in the synthesis of Antidote to anthrax lethal factor intoxication, bacterial RNA polymerase inhibitors and bicyclic extended dipeptide surrogates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, S., et al.: Bioorg. Med. Chem. Lett., 21, 2030 (2010); Pronin, S., et al.: J. Am. Chem. Soc., 132, 14394 (2010); Ranatunga, S., et al.: J. Org. Chem., 75, 5113 (2010)

Applications N-BENZYLBENZAMIDE (cas# 1485-70-7) is a useful research chemical.

Applications 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol (cas# 77544-60-6) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3-Nitrobenzoylacetonitrile (cas# 21667-64-1) is a useful research chemical.

Stability Hygroscopic
Applications TRISPHENYL(3,3,3-TRIFLUOROPROP-1-YL)PHOSPHONIUM IODIDE (cas# 128622-15-1) is a useful research chemical.

Applications 1,1'-[1]Benzothieno[3,2-b][1]benzothiophene-2,7-diylbis[1-octanone] is the intermediate in the synthesis of C8-BTBT (C015010), which is a soluble organic semicoductor used in solution-processed organic field-effect transistors.
References Ebata, H., et al.: J. Am. Chem. Soc., 129, 15732 (2007); Izawa, T., et al.: Adv. Mat., 20, 3388 (2008)

Applications Benzenecarbothioic Acid is used in the preparation of anti-leishmanial activity. Also used in the preparation of agents for the treatment against Alzheimer’s disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Andrews, P. et al.: Aus. J. Chem., 66, 1297 (2013); Linning, P. et al.: Org. Biomol. Chem., 10, 8216 (2012);

Applications 5-Fluoro-2-mercaptobenzothiazole is used as a reagent in the synthesis of [[(benzothiazolyl)thio]methyl]phenyl]furanone derivatives with agrochemical fungicidal activities.
References Zhao, P., et al.: Youji Huaxue, 30, 1567 (2010);

Applications tert-Butyl N-(Benzyloxy)carbamate has been used in the synthesis of Deferoxamine Mesylate (D228980), an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients
References Bergeron RJ, et al. 1992. J Med Chem. Dec 11;35(25):4739-44Inati A, et al. 2010. Am J Hematol. Oct;85(10):782-6 Selim M, et al. 2010. Transl Stroke Res. Mar;1(1):35-9

Applications It can be used in the preparation of sanitizer for use in factories.
References Yuan, H., et al.: Sanitizer used in factory and preparation method thereof, CN 106038470 (2016)

Stability Light Sensitive
Applications 1-Benzyl-1,4-dihydronicotinamide (cas# 952-92-1) is a compound useful in organic synthesis.
References Mailliet, F., et al.: Biochem. Pharmacol., 71, 74 (2005), Sandanayaka, A., et al.: J. Material. Chemis., 17, 2540 (2007),

Applications b-Phenylethyl Furoate (cas# 7149-32-8) is a useful research chemical.

Applications Benzyltriphenylphosphonium bromide is a useful reactant and reagent for organic reactions and synthesis.
References Hajra, S., et al.: Chem. Comm., 47, 3981-82 (2011); Smith, M.J., et al.: Org. Lett., 2011, 13, 3396-98;

Applications 4-N-OCTYLOXYBENZOIC ACID (cas# 2493-84-7) is a useful research chemical.

Applications [(1-Fluoroethenyl)sulfinyl]benzene is an intermediate used in the synthesis of 13-Fluorodibenzo[a,i]pyrene (F588440), which is a polycyclic aromatic hydrocarbon (PAH) thus potentially exhibiting carcinogenic properties through activation of P450 mono-oxygenase enzymes. Also, it has unique electrical and optical properties due to being a conjugated macromolecule.
References Zhang, F. et al.: J. Org. Chem., 65, 3952 (2000); Amaladass, P. et al.: Tetra., 64, 7992 (2008);

Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.
References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);

Stability Hygroscopic
Applications [3-(Ethoxycarbonyl)propyl]triphenylphosphonium Bromide is a reactant used in the preparation of maresin 1, a potent anti-inflammatory and pro-resolving lipid mediator.
References Tungen, J.E., et. al.: Tetrahedron Lett., 56, 1843 (2015)

Applications Di-[2-(2,3-dichlorophenyl)aminoethyl]amine is prepared from 1-Bromo-2,3-dichlorobenzene(B687435) and Diethylenetriamine (D444255). 1-Bromo-2,3-dichlorobenzene is a reagent used in the preparation of selective nonpeptidic inhibitors of striatal-enriched protein tryosine phosphatase.
References Baguley, T.D., et al.: J. Med. Chem., 56, 7636 (2013)

Applications (E)-1-Phenyl-1-butene was used to study olefin oxidation by cytochrome P-450. It can be used to synthesize nonracemic allylic amines. It can also be used to prepare aryl oxiranes by direct epoxidation.
References Liebler, D., et al.: Biochem., 22, 5482 (1983); Liang, C., et al.: J. Am. Chem. Soc., 130, 343 (2008); Imuta, M., et al.: J. Org. Chem., 44, 1351 (1979)

Applications 3-(2,3-Dihydroxyphenyl)propionic acid is a degradation product of the aromatic compound Phenylpropionate (PP).
References Provencher, S., et al.: Biochemistry, 20, 33 (1981), Ferrandez, A., et al.: J. Bacteriol., 179, 2573 (1997), Torres, B., et al.: J. Biol. Chem., 278, 27575 (2003),

Applications 3-(1-(Ethylamino)cyclohexyl)phenol is a useful synthesis intermediate.

Applications 2-(diphenylacetyl)-3-hydrazino-1H-Inden-1-one is a useful chemical reagent.

Applications 5-Hydroxy-3-phenylbenzoic Acid can be used in biological study of preparation and identification of hydroxybenzoic acids as lactate receptor agonists and antilipolytics. It can also be used in discovery of new series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
References Duffy, B. C., et al.: Bioorg Med Chem Lett, 25, 2818 (2015), Dvorak, C. A., et al.: ACS Med Chem Lett, 3, 637 (2012)

Applications 7-Benzyloxy-10,11-dihydrodibenzo[b,f[[1,4]thiazepin-11-one (cas# 329217-07-4) is a compound useful in organic synthesis.

Applications N-[1-[3-(2-Ethoxyphenyl)-2,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl]acetamide is an intermediate in the synthesis of Vardenafil (V098001) related compounds.
References Olszewska, T., et al.: Tetahedron., 69, 474 (2013);

Applications (1R,2R,4R)-rel-1,2,4-Trimethylcyclohexane is present in jet fuel-derived liquids light fractions.
References Xie, G. et al.: Env. Sci. Tech., 37, 4751 (2003); Gentner, D. et al.: Env. Sci. Tech., 47, 11837 (2013);

Applications 4-tert-Butyl-N-phenylaniline may be useful in the synthetic preparation of amines via Buchwald-Hartwig amination reaction of aryl thioethers.
References Bismuto, A., et al.: ACS Catal., 10, 4630 (2020)

Applications Resorufin Benzyl Ether is a fluorogenic substrate for CYP (cytochrome P450-linked enzymes), commonly used for monitoring P450 activities in cell extracts and solutions.

Applications 3-((E)-(2,4-Dimethylphenyl)diazenyl)-2,4-dihydroxy-5-((4-sulfophenyl)diazenyl)benzoic Acid is an intermediate in the synthesis of Acid Orange 24 (A189835), which is used in trickling biofilters for wastewater treatment. Acid Orange 24 is used in suncare compositions. It also serves as a raw material for cosmetics. Mutagenicity test for dye compositions in cosmetics.
References Garzon-Zuniga, M. A., et al.: Water Environ. Res., 83, 107 (2011); Anon.: IP.com Journal, 11, 5 (2011); Muzzall, J. M., et al.: Mutat. Res., Genet. Toxicol. Testing, 67, 1 (1979)

Applications α,α,α-Trifluorotoluene, is used as a specialty solvent in organic synthesis and an intermediate in the production of pesticides and pharmaceuticals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Skelly, P. D., et al.: Handbook for Critical Cleaning, 1, 191 (2011);

Applications trans-2-(Chloromethyl)cyclohexanemethanol is an impurity of Lurasidone Hydrochloride (L474920), an antipsychotic used for treatment of schizophrenia.
References Ishiyama, T., et al.: Eur. J. Pharmacol., 572, 160 (2007); Cole, P., et al.: Drugs of the Fut., 33, 316 (2008)

Applications Benzo[b]thien-3-ylboronic acid is used in the synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar/glycoprotein sensing.
References Akay, S., et al.: Chem. Biol. Drug Des., 70, 279 (2007)

Applications 5-(4-aminophenyl)-1,3,4-oxadiazole-2-thiol (cas# 32058-82-5) is a useful research chemical.

Stability Air Sensitive
Applications 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one (cas# 569-77-7) is a useful research chemical.

Applications 4-(Methoxycarbonyl)phenylboronic Acid is used in the synthesis and evaluation of several organic compounds including that of 4-Cyclohexylbutyl-N-[(S)-2-oxoazetidin-3-yl]carbamate which is a potent inhibitor of intracellular NAAA activity. Also used in the design and synthesis of BMS-955176 which is a potent, orally active second generation HIV-1 maturation inhibitor.
References Nuzzi, A., et al.: Eur. J. Med. Chem., 111, 138 (2016); Rogueiro-Ren, A., et al.: ACS Med. Chem. Lett., 7, 568 (2016);

Applications N,5-diphenyl-1,3,4-thiadiazol-2-amine (cas# 1437-57-6) is a useful research chemical.

Applications 2-(2-Ethoxyphenyl)-5,7-dimethylimidazo[5,1-f][1,2,4]triazin-4(1H)-one is an intermediate in the synthesis of Vardenafil (V098001) related compounds.
References Haning, H., et al.: Bioorg. Med. Chem. Lett., 15, 3900 (2005); Olszewska, T., et al.: Tetrahedron., 69, 474 (2013);

Applications 3-Amino-2-hydroxybenzonitrile

Applications Methyl 2-chloro-6-nitrobenzoate

Stability Hygroscopic
Applications 5-(4-aminophenyl)-1,3,4-oxadiazol-2-ol (cas# 113118-47-1) is a useful research chemical.

Applications 2-Nitro-5-phenylthioaniline is a useful synthetic intermediate. It was used to synthesize methyl 5(6)-phenylsulfinyl-2-benzimidazolecarbamate as a potent anthelmintic.
References Averkin, E., et al.: J. Med. Chem., 18, 1164 (1975);

Applications ethyl 3,5-dimethylbenzoate (cas# 21239-29-2) is a useful research chemical.

Applications An intermediate for the preparation of (+/-)-Taxifolin.

Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.

Applications 4-(2-Amino-3,3-dimethyl-1-oxobutyl)benzonitrile hydrochloride is used as a reagent to synthesize phenyloxobutanylpyridinylpiperazinecarboxamide derivatives, compounds that have TRPA1 receptor antagonistic properties.
References Svensson, M. & Weigelt, D. Preparation of Phenyloxobutanylpyridinylpiperazinecarboxamide Derivatives for Use as TRPA1 Receptor Antagonist. PCT Int. Appl. 2012050512. Apr 19, 2012.

Applications A versatile phosphitylating agent.
References Perich, J.W., et al.: Synthesis, 142 (1988)

Applications 3-Acetylphenylboronic acid

Stability Volatile
Applications Cyclohexyl Propionate (cas# 6222-35-1) is a useful research chemical.