6-membered Rings

Applications Cyanomethyl Methyl(phenyl)carbamodithioate (cas# 76926-16-4) is a useful research chemical.

Stability Moisture Sensitive
Applications Tributylphenyltin acts as a reagent for the synthetic preparation of tetrahydroisoquinolines and SAR as potential HIV-1 antivirals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Swidorski, J. J., et al.: Bioorg. Med. Chem. Lett., 26, 160 (2016)

Applications 2-Amino-N-benzylbenzamide can be used for drug discovery and pharmaceutical manufacturing.
References Amini-Rentsch, L., et.al., Ind. Eng. Chem. Res., 58, 10164-10171, (2019);

Applications Ethyl Benzoylformate is a general chemical reagent used in the preparation of diaminoethanediyl bismethylpyridinium salts for designing recyclable organocatalysts.
References Lisnyak, V. et al.: J. Org. Chem., 80, 8570 (2015);

Applications 2,5-Dimethylbenzene-1,4-diol is an intermediate used in the synthesis of β-Tocopherol (Racemic Mixture) (T625170), which is one of the naturally occurring forms of Vitamins E and is biologically less active than α-Tocopherol. This is the racemic mixture of all stereoisomers.
References Bianchi, G., et al.: Eur. J. Lipid Sci. Technology, 105, 229 (2003), Sakouhi, F., et al.: Food Chem., 108, 833 (2008)

Applications ethyl 3-oxo-2-phenylpropanoate (cas# 17838-69-6) is a useful research chemical.

Applications (E)-1-Phenyl-1-butene was used to study olefin oxidation by cytochrome P-450. It can be used to synthesize nonracemic allylic amines. It can also be used to prepare aryl oxiranes by direct epoxidation.
References Liebler, D., et al.: Biochem., 22, 5482 (1983); Liang, C., et al.: J. Am. Chem. Soc., 130, 343 (2008); Imuta, M., et al.: J. Org. Chem., 44, 1351 (1979)

Applications 3-(2,3-Dihydroxyphenyl)propionic acid is a degradation product of the aromatic compound Phenylpropionate (PP).
References Provencher, S., et al.: Biochemistry, 20, 33 (1981), Ferrandez, A., et al.: J. Bacteriol., 179, 2573 (1997), Torres, B., et al.: J. Biol. Chem., 278, 27575 (2003),

Applications 1,4-Dithiane has been studied to be used as a way for more efficient rechargeable iron-​air and nickel-​iron batteries through small addition of organo-sulur compounds to metal electrodes.
References Yang, B., et al.: Energy Environ. Sci., 7, 2753-63 (2014);

Impurity Ketoprofen EP Impurity G
Applications 3-​(2-Hydroxyethyl)​benzoic Acid (Ketoprofen EP Impurity G) is an impurity in the synthesis of Ketoprofen (K200800), anti-inflammatory (1,2); analgesic.
References 1. Ueno, K. et al.: J Med Chem. 1976 Jul;19(7):941-6. 2. Jamali, F. et al.: Clin Pharmacokinet. 1990 Sep;19(3):197-217.

Applications Ethyl 2-(2,6-Dichlorophenyl)acetate (cas# 90793-64-9) is a useful research chemical.

Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.

Applications 7-Benzyloxy-10,11-dihydrodibenzo[b,f[[1,4]thiazepin-11-one (cas# 329217-07-4) is a compound useful in organic synthesis.

Applications 2-(4-Hydroxybenzoyl)benzoic acid

Applications METHYL 2-HYDROXY-4-IODOBENZOATE (cas# 18179-39-0) is a useful research chemical.

Applications 1-(2,4-Bis(benzyloxy)phenyl)ethanone is a useful research chemical for organic synthesis and other chemical processes.
References Chen, D., et al.: Eur. J. Med. Chem., 87, 765 (2014); Malik, N., et al.: Tetrahedron Lett., 54, 4121 (2013)

Applications Ethyl (1S,3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxycyclohexane-1-carboxylate, is a building block used in various chemicla synthesis. It can be used for the preparation of six stereoisomers of diaminocyclohexane carboxamide as key intermediates for synthesis of factor Xa inhibitors.
References Wang, X. et al.: Tetrahedron, Vol.73, Iss.11, P1381-1388 (2017);

Applications 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide is used in the preparation of antihypertensive agents.
References Topliss, J. G., et al.: Journal of Medicinal Chemistry, 6, 122 (1963);

Applications 2-[(Dipropylamino)sulfonyl]benzoic Acid, is a building block used in various chemical synthesis.

Applications 1,3-Diphenylacetone (cas# 102-04-5) is a useful research chemical.

Applications 4-Isopropylphenylacetic acid (cas# 4476-28-2) is a useful research chemical.

Applications N-[[4-(Phenylmethoxy)phenyl]methyl]-2-[(3-thienylcarbonyl)amino]-4-thiazoleacetamide is derived from ethyl 2-amino-4-thiaxolacetate (E899330) which is used in the synthesis of various pharmaceutical and biologically active compounds including inhibitors and antibiotics.
References Inamoto, Y., et al.: J. Antibiot., 41, 828 (1988)

Applications [1-(3-Fluorophenyl)-1-tosyl]methyl isocyanide (cas# 321345-36-2) is a useful research chemical.

Applications 4-(3-Oxetanyl)benzenemethanol is a compound useful in organic synthesis.

Applications 7,8-Dihydroxy-3-(4-hydroxy-phenyl)-chromen-4-one (cas# 75187-63-2) is a useful research chemical.

Applications 4-Carboxymethylphenylboronic acid

Applications 1,3-Cyclohexanediol (cas# 504-01-8) is a useful research chemical.

Applications Methyl 4-Acetamido-2-hydroxy-3-(2-oxoethyl)benzoate is a useful research chemical for organic synthesis and other chemical processes.
References Kakigami, T., et al.: Chem. Pharm. Bull., 46, 42 (1998)

Applications Axitinib Iodo Tetrahydropyran is an analog of Axitinib (A794650). Axitinib (A794650) is a tyrosine kinase inhibitor. Axitinib is used in cancer therapy.
References Wasser, K., et al.: Eur. Radiol., 13, 80 (2003);Park, J., et al.: Clin. Cancer Res., 8, 1172 (2002); Bergers, G., et al.: J. Clin. Invest., 111, 1287 (2003);

Applications 5-Hydroxy-3-phenylbenzoic Acid can be used in biological study of preparation and identification of hydroxybenzoic acids as lactate receptor agonists and antilipolytics. It can also be used in discovery of new series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
References Duffy, B. C., et al.: Bioorg Med Chem Lett, 25, 2818 (2015), Dvorak, C. A., et al.: ACS Med Chem Lett, 3, 637 (2012)

Applications 4-(2,4,4-trimethylpentan-2-yl)benzene-1,2-diol (cas# 1139-46-4) is a useful research chemical.

Applications BENZYL CYANOMETHYLCARBAMATE (cas# 3589-41-1) is a useful research chemical.

Applications 4,4'-Dimethoxydiphenylamine is a diphenylamine derivative used as a chemical additive for cured rubber. 4,4'-Dimethoxydiphenylamine is highly toxic and may potentially induce chromosome abberation.
References Kel'man, G.Y. et al.: Kauch. Rez., 26, 28 (1967); Sofuni, T. et al.: Mutat. res. Gen. Toxicol. Test., 24, 175 (1990);

Applications 1-(1,3-Benzodioxol-5-yl)-1-hexanone is an intermediate used in the synthesis of 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-1-Hexanone (B207110), which is also known as MDPHP, is a synthetic cathinone.
References Fowble, K. L.; et al.: Talanta, 179, 546 (2018).

Applications N-(4-Bromo-2-picolinoylphenyl)-2-chloroacetamide is a derivative of 2-(2-Amino-5-bromobenzoyl)pyridine (A601785); an intermediate in the preparation of Bromazepam (B678500).
References Panderi, I., et al.: J. Pharm. Biomed. Anal., 17, 327 (1998); El-Haj, B., et al.: J. Anal. Toxicol., 25, 316 (2001); Hansen, S., et al.: J. Pharm. Biomed. Anal., 39, 322 (2005)

Stability Light Sensititve
Applications Ethynylbenzene, an aromatic hydrocarbon, is important in the petrochemical industry as an intermediate in the production of styrene, which in turn is used for making polystyrene, a common plastic material.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-(5-formylfuran-2-yl)benzoic Acid (cas# 88460-72-4) is a useful research chemical.

Applications 4-Benzyloxyphenylacetonitrile is an intermediate in the preparation of Desmethylvenlafaxine, an antidepressant and also in the preparation of RAGE antagonist for the treatment of Alzheimer's disease.
References Zhao, J., et al.: Zhongguo Yiyao Gongye Zazhi, 45, 601 (2014); Lee, Y. S., et al.: Bioorg. Med. Chem. Lett., 22, 7555 (2012)

Applications 1-(3,5-Bis(benzyloxy)phenyl)pentan-2-ol is an intermediate for the synthesis of 2''-Hydroxycannabidiol (H824820), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 2''-Hydroxycannabidiol can be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.
References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)

Applications 2,4,5-TRIMETHOXYBENZOIC ACID (cas# 490-64-2) is a useful research chemical.

Applications Methyl 4-amino-2-fluorobenzoate

Applications 3-Formylphenylboronic Acid is a reactant in the synthesis of I-BET726 (GSK1324726A), a potent tetrahydroquinoline ApoA1 up-regulator and selective BET bromodomain inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gosmini, R., et. al.: J. Med. Chem., 57, 8111 (2014)

Applications 2-(Tetrahydro-2H-pyran-3-yl)ethanol (cas# 1050493-77-0) is a useful research chemical.

Applications 2,4,6-Triisopropylbenzenesulfonyl hydrazide (cas# 39085-59-1) is a useful research chemical.

Applications 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases.
References McCarthy, T.D., et al. PCT Int. Appl. WO 2013102242 A1 20130711. Jul 11, 2013

Applications Diphenyl (Hydroxymethyl)phosphonate is a reagent for the synthesis of amidate prodrugs of novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.
References Mackman, R. L., et al.: Bioorg. Med. Chem., 18, 3606 (2010)

Applications α-Bromo-2,3,4,5,6-pentachlorotoluene is used to prepare trisubstituted symmetrical triazines containing halobenzyl groups as flame retardants.
References Herzlinger, A., et al.: Eur. Pat. Appl. (1989), EP 305196 A2 19890301

Applications 3-Phosphonobenzoic Acid (cas# 14899-31-1) is a useful research chemical.

Applications 1,2-O-Cyclohexylidene myo-Inositol (cas# 6763-47-9) is a compound useful in organic synthesis.

Applications p-Cyanobenzoic Acid Trimer is used in the synthetic preparation of Terbium Triazinetribenzoate Formate Metal Organic Framework (MOF).
References Han, Y., et al.: J. Mater. Chem. A Mater. Energy Sustain., 3, 24525 (2015)

Applications 4-(Methylamino)benzoic Acid (cas# 10541-83-0) is a compound useful in organic synthesis.

Applications cyclohexanecarbohydrazide (cas# 38941-47-8) is a useful research chemical.

Applications Benzyl pent-4-enoate (cas# 113882-48-7) is a useful research chemical.

Applications Wittig Reagent
References Yang, Z., et al.: Bioorg. Med. Chem., 17, 1071 (2009), Shearman, G., et al.: J. Mat. Chem., 19, 598 (2009),

Applications 3-{4-[(furan-2-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid (cas# 391229-93-9) is a useful research chemical.

Applications A benzoic acid derivative used in studies relating to Human UDP-glucuronosyltransferases as well as a reagent in acylation reactions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Xiong, Y. et al.: Biochemistry, 45, 2322 (2006); Chaudhary, A.G. et al.: J. Am. Chem. Soc., 116, 4097 (1994);

Applications Bis(4-diethylaminophenyl)methanol (cas# 134-91-8) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Light Sensitive
Applications 5-Vinylbenzo[d][1,3]dioxole (cas# 7315-32-4) is a useful research chemical.

Stability Light Sensitive
Applications PHENYL ETHENESULFONATE (cas# 1562-34-1) is a useful research chemical.

Applications Phenylsulfenyl Chloride is an intermediate used in the synthesis of Tabanone (T003450), which is found in oils of Trifolium pratense L. and is a potential natural anti-oxidant.
References Vlaisavljevic, S., et. al.: Molecules, 19, 713 (2014)

Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.
References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);

Applications (1S)-1-(4-phenylphenyl)ethan-1-ol (cas# 150283-02-6) is a useful research chemical.

Applications Decabromobiphenyl is a flame retardant and a standard for environmental testing and research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References EPA. Method 1668, (EPA 821-R-00-002) (1999); Zeng, L., et al.: Environ. Sci. Technol. 48, 12586 (2014)

Applications Benzo[b]thien-3-ylboronic acid is used in the synthesis and evaluation of dual wavelength fluorescent benzo[b]thiophene boronic acid derivatives for sugar/glycoprotein sensing.
References Akay, S., et al.: Chem. Biol. Drug Des., 70, 279 (2007)

Applications Precursor of Diazopropane. Carcinogen.
References Hecker, L.I., et al.: Cancer Res., 43, 4078 (1983),

Applications 2-(Phenylamino)nicotinic Acid (cas# 16344-24-4) is a useful research chemical.

Applications 5-(4-aminophenyl)-1,3,4-oxadiazole-2-thiol (cas# 32058-82-5) is a useful research chemical.