6-membered Rings

<p>Applications 2-(3-Butynyloxy)tetrahydro-2H-pyran is used as a reagent in the synthesis of Phomoidride D, a bridged, polycyclic, natural compound that has the ability to inhibit squalene synthase and can be used as an antihypercholesterolemic agent. 2-(3-Butynyloxy)tetrahydro-2H-pyran is also used as a reagent to prepare Rugulactone, a natural compound that is isolated from Cryptocarya rugulosa.<br>References Allais, F., et al.: Synthesis, 2010, 2787 (2010); Biller, S., et al.: Curr. Pharm. Des., 2, 1 (1996); Chen, C., et al.: J. Am. Chem. Soc., 122, 7424 (2000); Murphy, G., et al.: J. Org. Chem., 78, 477 (2013)<br></p>

<p>Applications Heptylbenzene is a useful synthetic intermediate. It is used in zirconia and titania based stationary phase capillary HTLC, to separate alkyl benzene derivatives using an acetonitrile-water eluent. It can also be used to prepare 3-chloropyridine-stabilized palladium imidazolylidene complexes as catalysts for Suzuki and Negishi cross-coupling reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kephart, T., et al.: Anal. Chim. Acta., 414, 71 (2000); O’Brien, C., et al.: Chem. Eur. J., 12, 4743 (2006)<br></p>

<p>Stability Hygroscopic<br>Applications [3-(3,4-dimethoxyphenyl)propyl](methyl)amine hydrochloride (cas# 83979-31-1) is a useful research chemical.<br></p>

<p>Applications 1,1,2,2-tetraphenylethane-1,2-diol (cas# 464-72-2) is a useful research chemical.<br></p>

<p>Applications 4-Mercaptobenzonitrile is a building block used as a reactant in the synthesis and in vitro anti-hepatitis B virus activities of some ethyl 6-bromo-5-hydroxy-1H-indole-3-carboxylates.<br>References Chai, H., et al.: Bioorg. Med. Chem., 14, 911 (2006);<br></p>

<p>Applications p-(Allyloxy)benzyl Alcohol is an intermediate in the synthesis of 2-amino-nicotinic acid benzyl ester derivatives as agrochemical fungicides.<br>References Jpn. Kokai Tokkyo Koho (2015), JP 2015089883 A 20150511.<br></p>

<p>Applications A useful synthetic intermediate for the preparation of novel antiinflammatory agents.<br></p>

<p>Applications 4'-Dimethylaminophenyl acetylene<br></p>

<p>Applications 5,7-Bis-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-hydroxy-4H-chromen-4-one (cas# 23405-70-1) is a compound useful in organic synthesis.<br>References Smith, J., et al.: Bioorg. Med. Chem., 15, 5018 (2007),<br></p>

<p>Applications 1-(2H-1,3-benzodioxol-5-yl)prop-2-en-1-ol (cas# 5208-87-7) is a useful research chemical.<br></p>

<p>Applications 4-Nitrotoluene is an explosive material.<br>References Wollseifen, Rainer, et al.: Separation, 35(1), 28-30 (2015);Cao, Anping, et al.: Nano Letters, 17(1), 1-7 (2017)<br></p>

<p>Applications Benzyl (2S)-2-carbobenzyloxyamino-6-hydroxyhexanoate (cas# 84246-49-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,5-Dimethoxytoluene (cas# 4179-19-5) is a useful research chemical.<br></p>

<p>Applications 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.<br></p>

<p>Applications Ethyl 2,2-Dimethyl-3-(4-mercaptophenyl)propionate (cas# 869853-73-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(3-Aminophenyl)ethanol is a useful compound for the synthesis of indolines and dihydrobenzofurans via iron and copper-catalyzed iodination and cyclization.<br>References Henry, M. C., et al.: J. Org. Chem., 84, 346 (2019)<br></p>

<p>Applications 6-Bromo-2H-1,4-benzoxazin-3(4H)-one is used in the synthesis of substituted benzoxazinones; selective 5-HT6 antagonists used for treating central nervous system diseases and gastrointestinal tract disorders.<br></p>

<p>Applications 1,2,4-Benzenetricarboxylic acid 1,2-Dihexyl Ester is a useful reagent for organic synthesis.<br></p>

<p>Applications Alkylating agent.<br></p>

<p>Applications 5-Hydroxytoluene-2,4-disulfonic Acid acts as a synthetic reagent in the sulfonation of 2 and 3-Methylphenol.<br>References Strandlund, G., et al.: Acta Chem. Scand., 33, 261 (1979)<br></p>

<p>Applications 3,4-Bis(phenylmethoxy)-benzoic Acid is a useful synthetic intermediate. It is an intermediate used to synthesize Jaboticabin (J210370) which is minor bioactive depside potent to treat chronic obstructive pulmonary disease.<br>References Wu, S., et al.: J. Agri. Food Chem., 61, 4035 (2013); Reynertson, K., et al.: J. Nat. Prod., 69, 1228 (2006)<br></p>

<p>Applications 6-Chloro-2,1,3-benzoselenadiazole (cas# 6343-86-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyltriphenylphosphonium Bromide is used as a wittig reagent. Ethyltriphenylphosphonium Bromide and other phosphonium salts show antiviral activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Romanov, G.V. et al.: Khim.-Farm. Zhur., 24, 28 (1990);<br></p>

<p>Applications 2-[hydroxy-(4-phenoxyphenyl)methylidene]propanedinitrile (cas# 330792-68-2) is a useful research chemical.<br></p>

<p>Applications 2-phenylcyclopentan-1-one (cas# 1198-34-1) is a useful research chemical.<br></p>

<p>Applications 3-Hydroxy-cyclohexanone is a chemical reagent used in organic synthesis. Used in enantioselective conjugate-addition reactions as well as the cross coupling of enantioenriched secondary potassium β-trifluoroboratoamides.<br>References Molander, G. et al.: Adv. Synth. Catal., 355, 3037 (2013); Kitanosono, T. et al.: Chem. Asian J., 9, 179 (2014);<br></p>

<p>Applications Ethyl (E)-Benzohydroximate is a synthetic intermediate and building block used in organic synthesis. It is used as a reactant in the preparation of N-functionalized oxyalkenes.<br>References Sartori, G., Maggi, R.: Science of Synthesis, 32, 783 (2008);<br></p>

<p>Applications 4-benzylmorpholine-2-carbonitrile (cas# 126645-52-1) is a useful research chemical.<br></p>

<p>Applications (s)-2-phenyl-1-propanamine (cas# 17596-79-1) is a useful research chemical.<br></p>

<p>Applications 2-Acetylcyclohexanone is used in the synthesis of 1-(pyridyl)ethanol derivatives that can reduce keto-esters and ketones. Also used in the synthesis of phenothiazine derivatives that can inhibit protein farnesyltransferase molecules and some that show anti-proliferative activity.<br>References Baciu-Atudosie, L. et al.: Bioorg. Med. Chem. Lett., 22, 6896 (2012); Kawano, S. et al.: Biosci. Biotech. Biochem., 75, 1055 (2011);<br></p>

<p>Applications Tetrahydro-4-pyranol is a building block of various organic compounds and pharmaceuticals.<br>References Chan, A.W., et al.: J. Med. Chem., 53, 3086 (2010); Desjardins, A.E.. et al.: Phytochem., 27, 767 (1988);<br></p>

<p>Applications A benzoic acid derivative used in studies relating to Human UDP-glucuronosyltransferases as well as a reagent in acylation reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Xiong, Y. et al.: Biochemistry, 45, 2322 (2006); Chaudhary, A.G. et al.: J. Am. Chem. Soc., 116, 4097 (1994);<br></p>

<p>Applications N-Phenyl 2-Bromo-5-Fluorobenzamide (cas# 949443-48-5) is a useful research chemical.<br></p>

<p>Applications tert-Butyldimethyl(4-(nitrosophenyl)butoxy)silane is an intermediate used in the synthesis of (E)-S-(3-((4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)amino)-3-oxopropyl) methanesulfonothioate (H895230), which is a useful research chemical.<br></p>

<p>Applications 3-(4-Hydroxyphenyl)propyl Acetate is an intermediate used in the synthesis of compounds used in biological studies for biodistribution and elimination of xenoestrogen nonylphenol in Wistar rats.<br>References Shah, M. R., et al.: J. Chem. Soc. Pak., 33, 444 (2011);<br></p>

<p>Applications 2-amino-3-hydroxy-3-phenylpropanoic acid (cas# 7695-56-9) is a useful research chemical.<br></p>

<p>Applications 5-Amino-2-chlorobenzenesulfonamide (cas# 2015-19-2) is a compound useful in organic synthesis.<br>References Somers, F., et al.: Pharm. Pharmacol. Commun., 6, 89 (2000), D'Ambrosio, K., et al.: J. Med. Chem., 51, 3230 (2008),<br></p>

<p>Applications 4-(2-Amino-3,3-dimethyl-1-oxobutyl)benzonitrile hydrochloride is used as a reagent to synthesize phenyloxobutanylpyridinylpiperazinecarboxamide derivatives, compounds that have TRPA1 receptor antagonistic properties.<br>References Svensson, M. &amp; Weigelt, D. Preparation of Phenyloxobutanylpyridinylpiperazinecarboxamide Derivatives for Use as TRPA1 Receptor Antagonist. PCT Int. Appl. 2012050512. Apr 19, 2012.<br></p>

<p>Applications Benzyl p-Toluylketone (cas# 2001-28-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wu, Z., et al.: Bioorg. Med. Chem. Lett., 18, 2211 (2008), Gadad, A., et al.: Bioorg. Med. Chem., 16, 276 (2008),<br></p>

<p>Stability Air Sensitive<br>Applications methyl 2-(2-formylphenyl)acetate (cas# 63969-83-5) is a useful research chemical.<br></p>

<p>Stability Light Sensitive<br>Applications Ethyl 2,3-dibromo-3-phenylpropionate<br></p>

<p>Applications (1S,2S)-1,2-Diphenyl-1,2-ethanediamine (cas# 29841-69-8) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-(Phenylamino)nicotinic Acid (cas# 16344-24-4) is a useful research chemical.<br></p>

<p>Applications 4-(tert-Butoxycarbonyloxy)benzylalcohol (cas# 156281-11-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(dimethylamino)benzenesulfonamide (cas# 6162-21-6) is a useful research chemical.<br></p>

<p>Applications (-)-DIBENZOYL-L-TARTARIC ACID MONOHYDRATE (cas# 62708-56-9) is a useful research chemical.<br></p>

<p>Applications 3-(4-Biphenyl)propionic Acid is a reactant in the preparation of 1,3,4-oxadiazole containing histone deacetylase inhibitors with anticancer activity.<br>References Valente, S., et. al.: J. Med. Chem., 57, 6259 (2014)<br></p>

<p>Applications 3-(Cyclopropylaminocarbonyl)phenylboronic acid<br></p>

<p>Applications 3-Formylbenzene-1,2-dicarbonitrile is used in the synthesis of a complete series of soluble distyrylbenzenes (DSBs) featuring cyano substituents at the peripheral rings.<br>References Schweikart, K., et al.: Eur. J. Org. Chem., 293-302 (2001)<br></p>

<p>Applications N-Carbobenzoxy-1,4-diaminobutane HCl is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia.<br>References Teranishi, H.; et al.: PCT Int. Appl. 215 pp. Patent 2004 CODEN:PIXXD2<br></p>

<p>Applications Benzyl Acetoacetic Amide (cas# 882-36-0) is a compound useful in organic synthesis.<br>References Sakaki, J., et al.: Chem. Pharm. Bull., 37, 2952 (1989),<br></p>

<p>Applications 4'-Hydroxyazobenzene-4-carboxylic acid hydrate<br></p>

<p>Applications 2,4,6-Triisopropylbenzenesulfonyl Azide is a useful synthetic intermediate. It is used in the synthesis of Antidote to anthrax lethal factor intoxication, bacterial RNA polymerase inhibitors and bicyclic extended dipeptide surrogates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, S., et al.: Bioorg. Med. Chem. Lett., 21, 2030 (2010); Pronin, S., et al.: J. Am. Chem. Soc., 132, 14394 (2010); Ranatunga, S., et al.: J. Org. Chem., 75, 5113 (2010)<br></p>

<p>Applications N-BENZYLBENZAMIDE (cas# 1485-70-7) is a useful research chemical.<br></p>

<p>Applications Geranylgeranyltriphenylphosphonium Bromide (cas# 57784-37-9 ) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Formylbenzenesulfonic Acid is used in preparation method for 3-Phenyl-L-serine derivatives.<br>References Xu, W., et al.:PCT Int. Appl., (2020):<br></p>

<p>Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.<br>References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides &amp; Nucleotides, 2, 21 (1983)<br></p>

<p>Applications 4-benzylcyclohexan-1-one (cas# 35883-77-3) is a useful research chemical.<br></p>

<p>Applications Ethyl α-Bromo-β-phenylpropionate 90% (cas# 39149-82-1) is a compound useful in organic synthesis.<br></p>

<p>Applications A hydroxy derivative of dibenzothiophene. Coal model compound used in chemical coal cleaning studies with molten hydroxides.<br>References Nowak, M.A. et al.: Coal Prep., 7, 29 (1989); Nishioka, M. et al.: Anal. Chem., 57, 1327 (1985);<br></p>

<p>Applications N-{2-[(4-Hydroxyphenyl)sulfanyl]ethyl}acetamide (cas# 91281-32-2) is a useful compound for use as a skin-lightening agent; cosmetic applications.<br>References Parvez, S., et al.: Phytother. Res., 20, 921 (2006)<br></p>