6-membered Rings

<p>Applications (S)​-​(-​)​-​1-​Phenyl-​1-​propanol is a building block used in the synthesis of inhibitors of steroid 11-β hydroxylation in the adrenal cortex related to androgen production in the fetus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zolle, I. et al.: J. med. Chem., 51, 2244 (2008);<br></p>

<p>Applications 5-PHENYL-1,2,4-TRIAZIN-3-AMINE (cas# 942-60-9) is a useful research chemical.<br></p>

<p>Applications (-)-DIBENZOYL-L-TARTARIC ACID MONOHYDRATE (cas# 62708-56-9) is a useful research chemical.<br></p>

<p>Applications 2-Cyclohexylideneacetic acid (cas# 1552-91-6) is a useful research chemical.<br></p>

<p>Applications Dibenzo[b,d]furan-2-sulfonic acid (cas# 83863-63-2) is a useful research chemical.<br></p>

<p>Applications 4-Biphenylacetonitrile is a useful synthetic intermediate. It was used to study the adsorption orientation of the biphenyl derivatives on the Au colloidal surfaces with α-cyclodextrins. 4-Biphenylacetonitrile on condensation reaction with ethyl phenyl propiolate yields biphenyl derivatives of acetylenic β-ketocyanide.<br>References Lee, J., et al.: Bull. Korean. Chem. Soc., 30, 1637 (2009); Al-Jallo, H., et al.: J. Chem. Eng. Data, 17, 513, (1972)<br></p>

<p>Applications 3,3-DIPHENYLPROPANOL (cas# 20017-67-8) is a useful research chemical.<br></p>

<p>Applications 2-Amino-4-hydroxybenzoic acid (cas# 38160-63-3) is a useful research chemical.<br></p>

<p>Applications 1,2-O-Cyclohexylidene myo-Inositol (cas# 6763-47-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-(Methylamino)benzoic Acid (cas# 10541-83-0) is a compound useful in organic synthesis.<br></p>

<p>Applications tert-Butyl 2-Aminobenzoate is a useful reagent for preparing alkylamino quinazolinones.<br>References Lu, C., et al.: J. Org. Chem., 83, 1154 (2018)<br></p>

<p>Applications Intermediate for the preparation of Neophytadiene.<br>References Marson, C.M., et al.: Bioorg. Med. Chem. Lett., 12, 255 (2002).<br></p>

<p>Applications 1,4-Dicyanobenzene is used in the preparation of aryl nitriles.<br>References Lee, H.G., et. al.: J. Am. Chem. Soc., 137, 648 (2015)<br></p>

<p>Applications 4-Nitro-benzeneethanol is a useful synthetic intermediate. It can be used to synthesize N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptor. It can also be used to prepare 2-aza-2'-deoxyinosine-containing oligodeoxyribonucleotide duplexes.<br>References Piscitelli, F., et al.: J. Med. Chem., 55, 5627 (2012); Acedo, M., et al.: J. Org. Chem., 60, 6262 (1995)<br></p>

<p>Applications Cyanomethyl Methyl(phenyl)carbamodithioate (cas# 76926-16-4) is a useful research chemical.<br></p>

<p>Applications 5-Bromo-2-ethoxy-benzenesulfonyl chloride<br></p>

<p>Applications 3-(4-Hydroxyphenyl)propionitrile (cas# 17362-17-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-(2H-1,3-benzodioxol-5-yl)prop-2-en-1-ol (cas# 5208-87-7) is a useful research chemical.<br></p>

<p>Applications 4-Nitrotoluene is an explosive material.<br>References Wollseifen, Rainer, et al.: Separation, 35(1), 28-30 (2015);Cao, Anping, et al.: Nano Letters, 17(1), 1-7 (2017)<br></p>

<p>Applications Benzyl (2S)-2-carbobenzyloxyamino-6-hydroxyhexanoate (cas# 84246-49-1) is a compound useful in organic synthesis.<br></p>

<p>Applications 3,4-dihydro-2H-1-benzopyran (cas# 493-08-3) is a useful research chemical.<br></p>

<p>Applications 3,5-Dimethoxytoluene (cas# 4179-19-5) is a useful research chemical.<br></p>

<p>Applications 3,4-Dihydroxyphenylglyoxal can be used in the preparation of adrenaline-like compounds.<br>References Fodor, G., et al.: Institute of Organic Chemistry of the University of Szeged, 71, 1045-1047 (1949);<br></p>

<p>Applications A potent γ-ketoaldehyde scavenger that has been shown to protects cardiac sodium channel (NaV1.5) from oxidant-induced inactivation<br>References Zagol-Ikapitte, I. et al.: Pharmaceutics, 2, 18 (2010); Nakajima, T. et al.: J. Mol. Cell. Cardiol., 48, 352 (2010); Davies, S.S. et al.: Biochem., 45, 15756 (2006);<br></p>

<p>Applications Methyl Phenylacetate is used as a reagent in the synthesis of various organic reactions, one of which is the synthesis of Vulpinic Acid (V850000); a lichen metabolite with anti-inflammatory properties.<br>References Shachak, M., et al.: Science, 236, 1098 (1987); Froberg, L., et al.: Lichenologist, 25, 83 (1993); Hesbacher, S., et al.: J. Chem. Ecology, 21, 233 (1995)<br></p>

<p>Applications 2-(6,6-Dimethyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane was used in the preparation of conformationally constrained cyclic carboxylic acid derivatives useful as GPR40 modulators for treating metabolic disorders.<br></p>

<p>Applications 2-(2-hydroxyphenyl)acetamide (cas# 22446-40-8) is a useful research chemical.<br></p>

<p>Applications Methyl 4-Ethyloxybenzoate acts as a reagent used in the synthesis of novel inhibitors targeting HDAC8 from schistosoma mansoni for treatment of Scistosomiasis.<br>References Heimburg, T., et al.: J. Med. Chem., 59, 2423 (2016)<br></p>

<p>Applications (2,5-Dimethylphenyl)boronic Acid is a useful synthetic intermediate. It can be used to prepare fluorenones/indenofluorenediones.<br>References Liu, T., et al.: Org. Lett., 13, 2452 (2011)<br></p>

<p>Applications N-Phenylanthranilic acid is used in biological studies for inhibitors of aldo-keto reductase 1C3 based on N-phenyl-aminobenzoates.<br>References Adeniji, A. O., et al.: J. Med. Chem., 55, 2311 (2012);<br></p>

<p>Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.<br></p>

<p>Applications 3-Aminocyclohexanol_x000D_(cis/trans mixture) (cas# 6850-39-1) is a compound useful in organic synthesis.<br></p>

<p>Stability Hygroscopic<br>Applications 5-Methylbenzotriazole intermediate.<br>References Vitale, G., et al.: Med. Chem., 5, 507 (2009), El-Sharief, A., et al.: Eur. J. Med. Chem., 44, 4315 (2009), Potter, A., et al.: Bioorg. Med. Chem. Lett., 20, 586 (2010),<br></p>

<p>Applications 5-Bromo-2-(morpholino)benzonitrile (cas# 1105665-08-4) is a useful research chemical.<br></p>

<p>Applications Can be used in the preparation of pyrrolylphenylsulfonates as dopamine D3 antagonists as well as in the preparation of substituted amidothiophene derivatives for use as 11-β-HSD1 inhibitors.<br></p>

<p>Applications (4S)-4-Ethyl-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione is a key intermediate in the synthesis of Irinotecan (I767500) and Camptothecin (C175150) analogs.<br>References Hsiang, Y., et al.: J. Biol. Chem., 260, 14873 (1985), Bao, Y., et al.: Chin. J. Med. Chem., 18, 263 (2008), Miao, Z., et al.: Bioorg. Med. Chem., 16, 1493 (2008),<br></p>

<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>

<p>Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.<br>References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);<br></p>

<p>Applications Methyl 4-Cyanobenzoate (cas# 1129-35-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,6-Anhydro-β-L-gulopyranose is an intermediate used in the synthesis of Troxacitabine (T805580), which is a nucleoside analogue with potential anticancer activity. Troxacitabine have been studied in patients with refractory lymphoproliferative diseases.<br>References Robak, T., et al.: Curr. Med. Chem., 18, 638 (2011); Kornblau, S.M., et al.: Clin. Cancer. Res., 16, 3721 (2010);<br></p>

<p>Applications tert-Butyldimethyl(4-(nitrosophenyl)butoxy)silane is an intermediate used in the synthesis of (E)-S-(3-((4-((4-(4-hydroxybutyl)phenyl)diazenyl)phenyl)amino)-3-oxopropyl) methanesulfonothioate (H895230), which is a useful research chemical.<br></p>

<p>Applications Maltol Benzyl Ether is intermediate of Malto (M160130), an fragrance molecule used in flavor enhancers and fragrances.<br>References Saghaie, L., et al.: Res. Pharma. Sci., 8, 185 (2013);<br></p>

<p>Applications 5-Ethyl-2-fluorophenylboronic acid<br></p>

<p>Stability Light Sensitive<br>Applications PHENYL ETHENESULFONATE (cas# 1562-34-1) is a useful research chemical.<br></p>

<p>Applications (2-Ethynylphenyl)boronic acid<br></p>

<p>Applications p-Anilinoaniline is an antioxidant that has shown to cause a reduction of NOx emissions from soybean biodiesel powered DI diesel engines but has increased CO and HC emissions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Varatharajan, K., Cheralathan, M.: Fuel Process Technol., 106, 526 (2013)<br></p>

<p>Applications 4-amino-N-(2,6-dimethylphenyl)benzamide (cas# 787-93-9) is a useful research chemical.<br></p>

<p>Applications Methyl 2-(2-Hydroxyphenyl)acetate is used as a reactant in the preparation of caffeic acid phenylethyl esters as  antiproliferative agents.<br>References Xie, Jin, et al.: Bioorg. &amp; Med. Chem. Let., 27(2), 131-134 (2017)<br></p>

<p>Applications N-(p-Fluorophenyl)-hydroxylamine, is a reactant used in various chemical synthesis, such as in preparation of spiro-isoxazoline and spiro-isoxazolidine derivatives of tomentosin.<br>References Zaki, M., et al.: RSC Advances, Vol. 7, Iss 11, P: 6523-6529 (2017);<br></p>

<p>Applications Ethoxybenzene is a reagent used in the synthesis of benzenesulphonylurea derivatives as anti-hyperglycaemic agents and various PTP1B inhibitors.<br>References Liu, P. et al.: Bioorg. Med. Chem., 23, 7079 (2015);<br></p>

<p>Applications Methyl (2S)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate<br></p>

<p>Applications 1-Hydroperoxy-1-​phenylethane is derived from α-Methylbenzenemethanol (M226185), which is a chemical reagent used in the synthesis of secondary aromatic and amino-alcohols.<br> E0<br>References Xu, G. et al.: Tetrahedron Lett., 54, 5026 (2013); Srimani, D et al.: Chem. Comm., 49, 6632 (2013);<br></p>

<p>Applications 1-Cyclohexylethanone is used in the synthesis of thiosemicarbazide derivatives which exhibits biological activity.<br>References Venkatesh, K., et al.: J. Chem. Pharm. Res., 7, 437-445 (2015)<br></p>

<p>Applications Benzofuran-3(2H)-one is a useful research chemical, an intermediate used in the catalytic asymmetric synthesis of chiral benzofuranones.<br>References Li, Y., et al.: Adv. Synth. Catal., 356, 1172 (2014); Huang, Z., et al.: Org. Lett., 19, 3524 (2017)<br></p>

<p>Applications Used in the preparation of antifungal agents.<br>References Del Poeta, M. et al.; Antimicrob. Agents Ch., 42, 2495 (1998)<br></p>

<p>Applications 3-(Cyclopropylaminocarbonyl)phenylboronic acid<br></p>

<p>Applications 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid is a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.<br>References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)<br></p>

<p>Stability Moisture Sensitive<br>Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.<br>References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);<br></p>

<p>Applications 2-(Diphenylphosphoryl)acetic acid (cas# 1831-63-6) is a useful research chemical.<br></p>

<p>Applications N-Carbobenzoxy-1,4-diaminobutane HCl is used in the synthetic preparation of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors of human sodium-glucose cotransporter 1 (SGLT1) for preventives or therapeutics for diseases related to hyperglycemia or galactosemia.<br>References Teranishi, H.; et al.: PCT Int. Appl. 215 pp. Patent 2004 CODEN:PIXXD2<br></p>

<p>Stability Hygroscopic<br>Applications Diphenylphosphinodithioic acid is used in the extraction of rhodium from nitrate media using phosphinic acids. It also functions as a new materials for microelectronic and molecular electronic devices.<br>References Samuels, A. C., et al.: Solvent Extraction and Ion Exchange, 33, 418 (2015)<br></p>

<p>Applications (3,5-Dimethoxyphenyl)acetonitrile (cas# 13388-75-5) is a compound useful in organic synthesis.<br></p>

<p>Applications Butyl Benzenesulfonate is an aryl-sulfonic acid ester found in drug substances. Butyl Benzenesulfonate is also used as a plasticizer in concrete preparation.<br>References Taylor, G.E. et al.: J. Chrom. A, 1119, 231 (2006); Gentsler, I.V. et al.: Izvest. VOZOV Stroit. Arkhit., 1, 67 (1970);<br></p>

<p>Applications (1S,3R,4S)-Ethyl 4-Amino-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylate Oxalate has been used as a reactant for the preparation of oxadiazole compounds containing cyclohexanediamine moiety.<br></p>

<p>Stability Air Sensitive<br>Applications Can be used as a building block for chiral ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 6-Bromo-2H-1,4-benzoxazin-3(4H)-one is used in the synthesis of substituted benzoxazinones; selective 5-HT6 antagonists used for treating central nervous system diseases and gastrointestinal tract disorders.<br></p>

<p>Applications 2-Ethoxy-4-ethoxysulfonylbenzoic Acid is a derivative of Methyl 2-Ethoxybenzoate (M220113), a useful chemical reagent, used in the synthesis and antibacterial triazoles and oxadiazoles, as well as sulfonamide compounds.<br>References Shi, Z. et al.: Compt. Rend. Chim., 18, 1320 (2015);<br></p>

<p>Applications 4,5,6,7-Tetrahydro-7-oxo-benzo[b]thiophene-4-carbonitrile is a useful synthetic intermediate.<br></p>

<p>Applications 4-Formylbenzenesulfonic Acid is used in preparation method for 3-Phenyl-L-serine derivatives.<br>References Xu, W., et al.:PCT Int. Appl., (2020):<br></p>

<p>Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.<br>References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides &amp; Nucleotides, 2, 21 (1983)<br></p>

<p>Applications Methyl 3-(Hydroxymethyl)benzoate is used in the synthetic preparation of N-acylhydrazone derivatives as lactate dehydrogenase A inhibitors.<br>References Rupiani, S., et al.: J. Med. Chem., 101, 70 (2015)<br></p>