Pharmaceutical Standards

Applications 2’,4’,6’-Trihydroxy-3’,5’-diprenyldihydrochalcone, can be used in synthesis of new diterpene and new dihydrochalcone derivatives.
References Bohlmann, F., et al.: Phytochemistry (Elsevier), Vol. 19, P: 873-9 (1980);

Applications (1,2,5,6-Tetramethyl-d6)naphthalene is the labeled analogue of 1,2,5,6-Tetramethylnaphthalene (T303675), a polycyclic aromatic hydrocarbon that has been found in petroleum.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Forster, P.G., et. al.: J. Chromatogr., 483, 384 (1989)

Applications Testosterone Heptanoate-6,6,7,7,7-d5 (CAS# 1263095-31-3) is a useful isotopically labeled research compound.

Applications 3-Hydroxy-2-naphthoic Acid-d6 is an intermediate used in the synthesis of Pamoic Acid-d10 (P173502), which is a labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.
References Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

Applications Forsythoside A is used as an antiinflammatory agent in traditional Chinese medicine.
References Li, H. et al.: Phytother. Res., 25, 338 (2011);

Applications Perchlorate salt derivative of Adenosine (A280400), nucleotide. It is also used in the synthesis of 2’-deoxy-7-methyladenosine.
References Fujii, T. et al.: Chem. Pharm. Bull., 42, 495 (1994);

Applications 3β,17,21-trihydroxy-5α-Pregnane-11,20-dione 21-Acetate can be used to synthesize 5α-pregnane-3β, 17α,21-triol-11,20-dione (Reichstein's substance D) and 5α-pregnane-3β, 11β,17α,21-tetrol-20-one (Reichstein's substance V).
References Chamberlin, E., et al.: J. Amer. Chem. Soc., 77, 1221 (1955);

Applications 3’-Chloro-4’-hydroxyacetophenone (cas# 2892-29-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Hygroscopic
Applications A main Levomepromazine metabolite
References Hals, P., et al.: Human Toxicol., 3, 497 (1984), Cutroneo, P., et al.: J. Pharm. Biomed. Anal., 41, 333 (2006),

Applications N-(Phenyl)-2-naphthylamine is a reagent in the preparation of unsymmetrical triaryldiamines as thermally stable hole transport layers for various organic LEDs.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koene, B. et al.: Chem. Mat., 10, 2235 (1998);

Applications 1,2,3,4-Tetrahydro-1,2,5-naphthalenetriol is a a reagent used in pharmaceutical synthesis.

Applications 5-Amino-1-naphthol is a reagent in the preparation of 5-hydroxy duloxetine. It is also used in the preparation of tetrahydronaphthol-, naphthol-, sulfonamide-, phenyl-, and heterocyclic-TRPV1 antagonists.
References Urbahns, K., et al.: Bioorg. Med. Chem. Lett., 22, 3408 (2012);

Applications 5-(3'-Hydroxybenzyl)hydantoin (cas# 216956-20-6) is a compound useful in organic synthesis.

Applications Labelled 1-Naphthol (N367990). Used in the manufacturing of dyes, intermediates, synthetic perfumes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N3-Methanethiosulfonylethyl Lumiflavin is a derivative of the Lumiflaviin (L473900), a toxic photolysis product of vitamin B2.

Applications 5-Methoxysalicylic acid

Applications Protected metabolite of Theobromine.
References Tarka, S.M., et al.: Clin. Pharmacol. Therap., 34, 546 (1983), Bonati, M., et al.: Toxicology, 30, 327 (1984)

Applications 2-Bromo-3'-nitroacetophenone is a reagent used the preparation of arylthiazolidinone derivatives which have BRD4 bromodomain inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhao, L., et al.: J. Med. Chem., 56, 3833 (2013);

Applications An intermediate of synergistic pesticide Boscalid. Also, used in the preparation of thieno[2.3-b]pyrrole derivatives as cannabinoid receptor agonists useful in mono- and combination therapy of diseases.
References Granger, D., et al.: Arthritis Rheum., 37, 1053 (1994), Robinson, R., et al.: J. Med. Chem., 39, 10 (1996),

Applications 4-Amino-2,6-dichloro-3-nitropyridine (cas# 2897-43-0) is a compound useful in organic synthesis.
References Palmer, A., et al.: Bioorg. Med. Chem., 16, 1511 (2008),

Applications 3'-O-Levulinoyl-N-benzoyl-2'-deoxyadenosine is a protected nucleotide derivative/building block.
References Kiuru, E., et al.: Helvetica Chimica Acta, 96, 1997-2008 (2013);

Applications Used in the synthesis of phenacetin metabolites.
References Focella, A. et al.: Can. J. Chem. 50, 2025 (1972)

Applications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (cas# 15717-45-0) is a compound useful in organic synthesis.
References Kazmers, I.S., et al.: Science, 214, 1137 (1981), Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

Applications CMPD101 is a potent and selective GRK2/3 inhibitor.
References Lowe, J.D., et al.: Mol. Pharmacol., 88, 347 (2015); Ikeda, S., et al.: PCT Int. Appl. WO 2007034846 A1 20070329. Mar 29, 2007

Applications 4-Chloro-2-iodobenzeneacetic Acid Methyl Ester is an intermediate in the synthesis of aldosterone synthase inhibitors.
References Rostovskii, N., et al.: Org. Lett., 4148 (2015);

Applications 2,2'-(2-Hydroxypropane-1,3-diyl)bis(1H-isoindole-1,3(2H)-dione) is a reagent used for the preparation of functionalized tripodal ligands and their metal complexes for imaging applications.
References Dunn, T.J., et al.: PCT Int. Appl., 1995:494561 (1995)

Applications N4-ACETYLCYTOSINE (cas# 14631-20-0) is a useful research chemical.