Glycoscience

<p>Nematode glycan mediating activation of macrophages</p>

<p>3’-O-Acetyl-1,2,5-tri-O-benzoyl-4-a-C-vinyl-D-ribofuranose is a modified sugar that is synthesized by the click chemistry method. It has been fluorinated and methylated on the 2’ and 3’ positions of the ribose ring. The compound is also glycosylated with a CDP chitosan to increase stability in plasma. This product has high purity and can be custom synthesized to customer specifications.</p>

<p>N-(5-Carboxypentyl)-deoxymannojirimycin hydrochloride is a high purity, custom synthesis, CAS No. 104154-10-1. It is a sugar that contains the Click modification, fluorination, glycosylation, and synthetic modifications. It contains methylation, modification and oligosaccharide or monosaccharide saccharides. This compound has been modified by Carbohydrate Complex.</p>

<p>Man-4 N-glycan is an oligosaccharide that is modified with a methyl group at the 4th carbon atom. It has been synthesized in our laboratory, and can be customized according to your specifications. Man-4 N-glycan is highly pure and has a purity of 98% or higher. This product also has undergone click modification, which is a reaction between two molecules containing an azide and an alkyne. The resulting product contains a fluorine atom on the 4th carbon atom. Contact us for more information about this product.</p>

<p>Melezitose is a non-reducing trisaccharide that is produced by many plant sap-consuming insects, such as aphids (e.g. Cinara pilicornis).  Melezitose is a component of honeydew which acts as an attractant for ants and also as food for bees. Partial hydrolysis of melizitose releases glucose and turanose, an isomer of sucrose.</p>

<p>Methyl α-D- glucopyranoside is a methylated sugar used as an inhibitor of lectin-conjugate binding. Methyl α-D- glucopyranoside is commonly used in protein purification for eluting glycoproteins and other glycoconjugates from affinity chromatography columns of agarose lectin. Methyl α-D- glucopyranoside is also known as Methyl alpha-D-glucoside or alpha-Methyl-glucoside.</p>

<p>N-(Succinyl)-O-b-D-lactosylhydroxylamine is a methylation product of b-D-lactosylhydroxylamine. It has a CAS number and can be modified with Click chemistry, which is a method of chemical modification using copper (II) ions. N-(Succinyl)-O-b-D-lactosylhydroxylamine can also be modified with other chemicals, such as an amine or carboxylic acid, to create an oligosaccharide. This product is synthesized in high purity and has a high glycosylation yield. It is used for research purposes and can be custom synthesized for any desired sugar.</p>

<p>(5S, 8S, 9S) -8- [(4S) - 2, 2-Dimethyl- 1, 3- dioxolan- 4- yl] - 9- hydroxy- 2, 2- dimethyl- 1, 3, 7- trioxaspiro[4.4] nonan- 6- one is a synthetic molecule that has been modified to include fluorine atoms at the C3 and C4 positions. It is a sugar that is found in many plants and animals. This sugar can be methylated or modified with other molecules to form complex carbohydrates. The ability of this sugar to form oligosaccharides and polysaccharides makes it an important part of carbohydrate metabolism.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>Hyaluronic acid, a polysaccharide with alternating β (1,3) glucuronide and β (1,4) glucosamine residues labelled with 5-amino-fluorescein gives a yellow fibrous product, which is soluble in both water and electrolytes.  Fluorescein-labelled hyaluronic acid can be used as a probe to follow the fate of hyaluronan in vitro and greatly enhances the visualisation of the permeation of substrates through skin and other tissues. Other applications of fluorescein-labelled hyaluronic acid have been reported in cancer research.</p>

<p>Methyl-2,3,4-tri-O-benzoyl-6-bromo-6-deoxy-alpha-D-glucopyranoside is a sugar that belongs to the group of monosaccharides. It is a custom synthesis product that can be synthesized and modified according to customer's requirements. Methylation, fluorination and saccharide modification are possible and highly pure methylated products can be produced with high purity.</p>

<p>Carageenan is a mixture of gelling sulphated galactans extracted from red algae (typically Euchuma cottonii, Euchuma spinosum Mastocarpus stellata and Chondrus crispus). The structure of all carrageenans consists of a strictly alternating masked repeating unit of 1,3 linked α-D-galactose and 1,4 linked β-D-galactose with variable proportions of sulphate. The α-linked galactose residue occurs as α-3-6-anhydro-2-sulphate.<br>The images were kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Glycyl-disialyllacto-N-tetraose is a complex carbohydrate that contains a glycosidic bond between two monosaccharides. It has the molecular formula C9H18O4N2O8 and CAS number 327977-92-3. This compound can be modified with methylation, glycosylation, or fluorination to increase solubility and stability. Glycyl-disialyllacto-N-tetraose is also known as Oligosaccharide, CAS No., Polysaccharide, Modification, saccharide, Methylation, Glycosylation, Click modification and Carbohydrate.</p>

<p>1-O-Acetyl-a-D-galactopyranose is a carbohydrate that is synthesized from D-galactose and acetyl chloride. It's an Oligosaccharide, Polysaccharide, or Modification to saccharides that are found in nature. This product can be modified with methylation, glycosylation, or carbocationic reactions. 1-O-acetyl-a-D-galactopyranose is used for click chemistry reactions and has a CAS number of 496924551.</p>

<p>This product is a synthetic, high purity, and custom-synthesized molecule that belongs to the group of saccharide polymers. It is synthesized by methylation of 4-methoxyphenyl 4-O-[3-O-(2,3,4,6-O-acetyl-a-D-mannopyranosyl)-4,6-O-benzylidene-2-O-levulinoyl]-b-Dglucopyranoside and Click modification. This product has potent glycosylation activity with polysaccharides such as heparin and chondroitin sulfate. The synthesis of this product is completed through the use of a highly efficient and selective carbohydrate polymerization method.</p>

<p>2-Methoxycarbonylphenyl 2-acetamido-2-deoxy-b-D-glucopyranoside is a fluorinated monosaccharide that can be used as a glycosylation and polysaccharide modification agent. It has been shown to be useful for the synthesis of complex carbohydrates. This product is available in high purity, custom synthesis, and CAS No. 1093406-94-0.</p>

<p>1,2-Di-O-acetyl-5-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose is a methylated saccharide. It has been modified with a click modification and has been synthesized using glycosylation and Oligosaccharides. This product can be used for custom synthesis and is available in high purity and with a CAS No. 159099-24-8. The molecular weight of this compound is 386.14 g/mol.</p>

<p>Methyl 6-chloro-6-deoxy-a-D-glucopyranoside is a custom chemical synthesis that can be modified, fluorinated, methylated, monosaccharide and polysaccharide. It is an oligosaccharide sugar with CAS No. 4144-87-0. This chemical is synthesized by glycosylation of the saccharide.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Methyl 3,6-di-O-benzyl-2-deoxy-a-D-glucopyranoside is a sugar derived from the natural carbohydrate sucrose. It is custom synthesized and glycosylated with an oligosaccharide. Methyl 3,6-di-O-benzyl-2-deoxy-a-D-glucopyranoside can be used in the synthesis of polysaccharides and other carbohydrates. This product has been modified using click chemistry to attach a methyl group at the C3 position of the glucose moiety. This modification is useful for glycosylation reactions that require a specific location on the sugar for attachment of an amino acid or peptide. Methyl 3,6-, di-, O-, benzyl--2, deoxy--A--D--glucopyranoside has CAS number 51139–03–5 and is available in high purity.</p>

<p>Suppresses tumor angiogenesis; pro-apoptotic</p>

<p>Ethyl 2,4-di-O-acetyl-6-azido-6-deoxy-a-D-thiomannopyranoside is a synthetic compound derived from the sugar thiomalan. It is not naturally occurring or found in any living organism and has been synthesized for research purposes. The molecular weight of this compound is 693.92 g/mol and the chemical formula is C14H24N2O8. This compound has been shown to have various glycosylation modifications and can be used for custom synthesis by request.</p>

<p>Propargyl a-D-glucopyranoside is a high purity custom synthesis sugar. It is synthesized by Click modification, fluorination, and glycosylation followed by methylation. Propargyl a-D-glucopyranoside can be used for the modification of oligosaccharides and monosaccharides to produce complex carbohydrates.</p>

<p>N-Acetyl-a-D-glucosamine-1-phosphate disodium salt (NACP) is a complex carbohydrate that is used as a synthetic sugar. It can be used to modify saccharide, glycosylations, or methylations. NACP has been shown to be stable at high temperatures and pressures. The compound has been fluorinated and click modified for the synthesis of other sugars. NACP has CAS No. 31281-59-1, which is the molecular formula of C8H14FO6Na2O11P2.</p>

<p>4-O-(b-D-Glucopyranosyl)-a-D-thioglucopyranose is a synthetic sugar that is used in the synthesis of glycosides and carbohydrates. This product is available as a custom synthesis, but can also be found in the form of an oligosaccharide or monosaccharide. It has a high purity and can be used to produce fluorinated sugars.</p>

<p>Heparin is a glycosaminoglycan which is a complex carbohydrate that contains repeating disaccharide units of glucosamine and N-acetylglucosamine. Heparin has been shown to inhibit the activity of bacterial enzymes involved in fibrinolysis, such as plasminogen activator inhibitor 1 (PAI-1), and may act as an anticoagulant. Heparin is often used as an anticoagulant in patients with thrombotic disorders, including deep vein thrombosis, pulmonary embolism, or heart attack. Heparin also acts as a cofactor for the activation of clotting factors II (thrombin), VII, IX, X, XI and XII. In addition, it inhibits the activation of factor XIII by preventing its conversion from its inactive form into active factor XIIIa. The molecular weight of heparin is approximately 10 kilodaltons (kDa) and it has a molecular formula</p>

<p>(1S) -1- [(2S, 3R) - 3- Hydroxy- 1- (phenylmethyl) - 2- azetidinyl] -1, 2- ethanediol is an enantiomerically pure sugar with a CAS number of 1322748-34-4. It is a synthetic sugar that contains a saccharide. The sugar has been modified to contain an azetidinyl and an ethanediol group. This modification gives the sugar a glycosylation and methylation pattern. The product was synthesized in the lab, unlike natural sugars which are derived from plants or animals.</p>

<p>GA1-ganglioside is also known as asialo-GM1 ganglioside. Autoimmune responses to GA1 ganglioside and high titers of anti-GA1 antibodies have been associated with neuromotor disorders, such as, motor neuron disease, multifocal motor neuropathy, and Guillain-Barré syndrome (Kolter, 2006). Anti-GA1 antibodies are also associated with Borrelia burgdorferi infection and Lyme disease (Djellaoui, 2016).</p>

<p>3-O-(a-D-Mannopyranosyl)-D-mannopyranose 1-O-propylamine acetate salt is a methylated saccharide. It is an oligosaccharide that can be synthesized from D-mannose and pyruvic acid, with the addition of a proton donor. This product is used in the synthesis of polysaccharides due to its high purity and low cost. The methyl group on this molecule reacts with the carbonyl group on the sugar to form an ester, which makes it resistant to hydrolysis by enzymes. 3-O-(a-D-Mannopyranosyl)-D-mannopyranose 1-O-propylamine acetate salt is also fluorinated and can be used as a click modification in proteins or carbohydrates.</p>

<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a lectin that has been shown to have an affinity for bacterial cells. It has been shown to be effective against Gram-positive and Gram-negative bacteria, with the exception of mycobacteria. 1,2,3,5-Tetra-O-acetyl-D-xylofuranose binds to the terminal sugar of the cell wall carbohydrate chains of these cells by means of its oligosaccharide side chain. The binding causes conformational changes in the bacterial membrane and disrupts the ion gradient across it. This leads to an influx of water into the cell and subsequent death.</p>

<p>1,2,3,4-Tetra-O-pivaloyl-6-O-(tert-butyldiphenylsilyl)-a-D-mannopyranose is a glycosylated sugar that can be methylated and fluorinated. It has high purity and is custom synthesized for the synthesis of oligosaccharides. This sugar has CAS number 29091-01-9 and is used in the synthesis of polysaccharides.</p>

<p>1-Deoxy-3,4-O-isopropylidene-L-tagatose is a synthetic sugar that is modified by the addition of a fluorine atom at the 1 position. This modification prevents the enzyme glycosidase from cleaving this sugar and releasing glucose. 1DILT can be used to produce glycans with different structures, including complex carbohydrates. The CAS number for this product is 7062-93-5.</p>

<p>Bisbiguanide antiseptic and disinfectant used in topical antibacterial products</p>

<p>Benzyl 4-O-(b-D-galactopyranosyl)-b-D-xylopyranoside is a synthetic monosaccharide that has been modified with fluorine. This compound is used to modify complex carbohydrates like glycosaminoglycans and glycoproteins. It is also used in the synthesis of oligosaccharides and polysaccharides, as well as in click chemistry. Benzyl 4-O-(b-D-galactopyranosyl)-b-D-xylopyranoside is available for custom synthesis, and can be ordered in high purity.</p>

<p>Tridecyl beta-D-maltopyranoside is a synthetic saccharide that has been modified with fluorination and methylation. The carbohydrate can be used in the synthesis of glycosylated proteins. The product is available for custom synthesis, and it is offered in high purity form.</p>

<p>This is a custom synthesis of (5R, 6R, 7R, 8S) -5, 7-dihydroxy-8- (hydroxymethyl) -1-azabicyclo[4.2.0]octan-2-one. This compound has been fluorinated and methylated and has a monosaccharide modification.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>Lactose oleate is a fatty acid ester that can be used as an absorption enhancer. It has been shown to increase the absorption of drugs in both inorganic and organic forms. Lactose oleate can be used in assays to determine the profile and nucleophilic attack of fatty acids. Lactose oleate is lipophilic and biodegradable, making it suitable for use as an edible coating or as a membrane for cell culture. Lactose oleate can also be used as a substrate for immobilization studies, where it is immobilized on silica gel particles. This allows for its use in thermodynamic studies. Lastly, lactose oleate has been shown to have potential anti-inflammatory properties in caco-2 cells.</p>

<p>N-(4-Bromobenzyliden)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside is a custom synthesis that is an oligosaccharide. This product is a complex carbohydrate that can be modified with methylation, glycosylation and click modification. The saccharide unit in this product is a sugar or carbohydrate. It has high purity with fluorination and synthetic modifications.</p>

<p>Ethyl 2-deoxy-2-trichloroacetamido-b-D-thioglucopyranoside is a modified sugar which is synthesized by reacting an ethyl glycoside with trichloroacetonitrile. This product is a white, crystalline powder that can be used in the synthesis of complex carbohydrates and saccharides, as well as other chemical modifications such as fluorination and methylation. It has been shown to have high purity and custom synthesis capabilities.</p>

<p>Glycyl-monosialyllacto-N-neohexose I is a monosaccharide that is used as a building block in the synthesis of complex carbohydrates. It is custom synthesized and purified to high purity. This product can be fluorinated and methylated, which allows for the attachment of glycosyl groups. Glycyl-monosialyllacto-N-neohexose I is also a sugar with a CAS number. It has an average molecular weight of 137.14 g/mol and is made up of three atoms: carbon, hydrogen, and oxygen.</p>

<p>Methyl-beta-D-thiogalactopyranoside is a monosaccharide that is a member of the galactose family. It can be found in some foods, such as dairy products or soybean milk. Methyl-beta-D-thiogalactopyranoside has been shown to promote lactose transport in cells. This compound is also used as a diagnostic marker for certain types of cancers and can be used to study sugar transport in cells. Methyl-beta-D-thiogalactopyranoside has been shown to inhibit the enzyme activity of phosphatases and may be used for research purposes as a control for other experiments.</p>

<p>1,6-Anhydro-3-O-b-D-glucopyranosyl-b-D-glucopyranose is a glycosylation agent that is used in the synthesis of complex carbohydrates. It has been modified by methylation, click modification, and fluorination to produce 1,6 anhydro-3-[2-(N′-[1-(4-chlorophenyl)ethylidene]amino)-2-(N′-[1-(4-chlorophenyl)ethylidene]amino)]ethylidene]-b -D glucopyranoside. This product is CAS No. 60932-82-7 and can be custom synthesized to produce high purity and low impurities.</p>

<p>Cochineal is a natural dye that is extracted from the female cochineal insect. Cochineal is used in food and cosmetics, and as a red colorant in some pharmaceutical products. The carminic acid present in cochineal forms a stable complex with the anionic groups present in wool or silk, so it is not soluble in water. Cochineal has been shown to have genotoxic activity and can cause mutations at both the base-pairing level and at protein level. Cochineal has also been shown to be cytotoxic against human serum cells and disrupt mitochondrial membrane potential. Its optimum concentration for signal peptide detection by electrochemical impedance spectroscopy (EIS) was found to be 0.1 mM.</p>

<p>Methyl mandelate glucoside is a glycosylation product that is custom synthesized for its fluorination and methylation. The molecule has a complex structure, consisting of monosaccharides and polysaccharides. Methyl mandelate glucoside is a high-purity compound with a CAS number. This chemical is also modified by click chemistry to create an oligosaccharide.</p>

<p>O-(2,3,4,6-Tetra-O-benzyl-a-D-gal)-(1-4)-O-(2,3,6-tri-O-benzyl-b-D-gal)-(1-4)-2,3,6-tri-O-benzyl D glucal is a modification of the Oligosaccharide carbohydrate. It is synthesized by custom synthesis and is high purity. The CAS number for this product is . The monosaccharide in this product is methylated and glycosylated. This product has fluorination and saccharide properties.</p>

<p>Core antigen ABO trisaccharide conjugated to HSA via an aminophenyl ethyl spacer</p>

<p>Methyl 2,3,4-tri-O-acetyl-6-O-tert-butyldimethylsilyl-a-D-mannopyranoside is a fluorinated monosaccharide. It is used in the synthesis of oligosaccharides and polysaccharides. This chemical can also be used for glycosylation and click modifications. Methyl 2,3,4-tri-O-acetyl-6-O-tert-butyldimethylsilyl--a--D--mannopyranoside has CAS No.</p>

<p>(R)-3,6-O-Benzylidene-2,6-dideoxy-L-galacto(gluco)furanose is a synthetic carbohydrate that has been modified with the addition of a fluorine atom. This modification changes the properties of the sugar and allows it to be used as an effective anticancer drug. (R)-3,6-O-Benzylidene-2,6-dideoxy-L-galacto(gluco)furanose has been shown to inhibit the growth of tumor cells in vitro and in vivo. It is also capable of inhibiting the synthesis and activity of bacterial enzymes such as beta-glucosidase and alpha amylase.</p>

<p>Methyl 2,3-di-O-benzyl-4,6-O-(4-methoxybenzylidene)-a-D-mannopyranoside is a custom synthesis of a complex carbohydrate. It has been modified to include an Oligosaccharide and Polysaccharide, which are saccharides. This product can be used for the synthesis of glycosylation and carbonylation reactions. Methyl 2,3-di-O-benzyl-4,6-O-(4-methoxybenzylidene)-a-D-mannopyranoside is high purity with a fluorination process that ensures the highest quality.</p>