Glycoscience

<p>2,3,4,6-Tetra-O-acetyl-D-galactopyranose is a glycoside that has been used as an antigen in immunological studies and to study the role of fatty acids in cancer. This compound is phosphorylated to form 2,3,4,6-tetra-O-phospho-D-galactopyranose and reacts with primary alcohols to form transglycosylation products. 2,3,4,6-Tetra-O-acetylgalactopyranose also reacts with chloride ions to form disaccharides. As a result of these reactions 2,3,4,6-tetraacetylgalactopyranose has shown anticancer activity.</p>

<p>Octyl D-galactofuranoside tetraacetate is a fluorinated monosaccharide that is synthesized from octyl galactopyranoside. It is a synthetic oligosaccharide with a molecular weight of 806. Octyl D-galactofuranoside tetraacetate has been modified for glycosylation, methylation, and click modification. The chemical name is 4-O-(2-deoxy-beta-D-glucopyranosyl)galactopyranose 1,2,3,4,6-pentaacetate and it has CAS No. 223412-29-1. This product can be custom synthesized to order in high purity as per the customer's requirements.</p>

<p>1-O-Acetyl-2-deoxy-5-O-p-methoxybenzoyl-3-O-(N,N-diethylthiocarbamoyl)-Dribofuranose (1) is a fluorinated monosaccharide that is synthesized from 1,2:5,6:7,8:3',4'-hexamethyleneglucopyranosyl bromide and diethylthiocarbamic acid. This product has been shown to be an efficient glycosylation agent for complex carbohydrates and can be used in the synthesis of oligosaccharides and polysaccharides. It has also been modified by methylation and click chemistry.</p>

<p>1,2,3,5-Tetra-O-acetyl-L-arabinofuranose is an organic compound that belongs to the group of sugars. It is a component of many polysaccharides and glycoproteins. 1,2,3,5-Tetra-O-acetyl-L-arabinofuranose is a useful intermediate in the synthesis of lysine and theophylline. The most common method for deacetylation involves using triphenylphosphine and chlorine in dichloromethane or chloroform as solvent. This reaction yields 1,2,3,5-tetra-O-(chloroacetoxy)-L-arabinofuranose which can be purified by chromatography. The bioassay for 1,2,3,5-tetra-O-[chloroacetoxy]-L arabinofuranose was found to be similar to that for</p>

<p>Neocarratetraose-41-O-sulfate sodium salt is a high purity, synthetic oligosaccharide with a CAS number of 108321-78-4. It is an oligosaccharide that has been modified with methylation, saccharide, and Click modification. Neocarratetraose-41-O-sulfate sodium salt is used in the synthesis of complex carbohydrates and glycosylations. <br>Neocarratetraose-41-O-sulfate sodium salt is synthesized by reacting the sugar neocarratetraose with sulfuryl chloride to form the corresponding sulfonic acid chloride. The resulting compound is then treated with sodium hydroxide to produce its sodium salt form.</p>

<p>2,3,1',3',4',6'-Hexa-O-acetyl-sucrose is a custom synthesis carbohydrate with a complex structure. The chemical name for this compound is 2,3,1',3',4',6'-hexahydroxy-α-D-glucopyranosyl-(1→2)-β-D-fructofuranoside. It has the CAS number 52706-47-5 and the molecular weight of 593.54 g/mol. This product can be used in various applications including Oligosaccharides, Polysaccharides, Modification, saccharide, Methylation, Glycosylation, Click modification and Carbohydrate. 2,3,1',3',4',6'-Hexa-O-acetyl-sucrose is also a high purity product that is Fluorinated and Synthetic.</p>

<p>(R)-Naproxen acyl-b-D-glucuronide benzyl ester is a custom-synthesized molecule. The synthesis of this compound is accomplished by the modification of naproxen, which is a commercially available drug. The fluorination and methylation steps are accomplished to provide a more potent drug. This compound exhibits anti-inflammatory properties that may be due to its inhibition of prostaglandin synthesis.</p>

<p>Entacapone 3-b-D-glucuronide is a product of the human UDP-glucuronosyltransferase enzyme. It is used as a substrate in kinetic studies to determine the activity of this enzyme. The activity of this enzyme is also measured indirectly by measuring the conversion of 4-methylumbelliferone to 4-methylumbelliferone 3-β-D-glucuronide using an analytical method based on spectrophotometry. Entacapone 3-b-D-glucuronide has been shown to inhibit the catalytic action of butyrylcholinesterase, which can be useful in treatments for heroin addiction, Parkinson's disease and Alzheimer's disease.</p>

<p>3,5-Bis-O-(2,4-Dichlorobenzyl)-2-C-methyl-a-D-ribofuranose is a custom synthesis that can be modified by fluorination, methylation, and monosaccharide or oligosaccharide addition. This sugar has a molecular weight of 476.28 g/mol and CAS No. 94629-04-0. It is a polysaccharide that is glycosylated with sugar at carbons 1 and 2. 3,5-Bis-O-(2,4-Dichlorobenzyl)-2-C-methyl-a-D-ribofuranose is used as an intermediate in the synthesis of complex carbohydrates such as Glycogenin A (CAS No. 94629 04 0), which has been shown to have antihyperglycemic effects.</p>

<p>2-Acetamido-1,4-imino-1,2,4-trideoxy-L-arabinitol is a competitive inhibitor of the enzyme arabinitol dehydrogenase. This compound has been shown to be an enantiomer of 1,4-imino-1,2,4-trideoxyglucitol and inhibits the growth of Mycobacterium tuberculosis in vitro assays. 2AITDG also has inhibitory properties against macrophage cells and noncompetitive inhibitors against glycoprotein glycoconjugates. 2AITDG binds to endoplasmic reticulum chaperones such as BiP/Grp78 to inhibit protein folding and cellular proliferation. It may also inhibit protein synthesis by binding to ribosomes or blocking the activity of factors involved in transcription and translation.</p>

<p>4-Aminophlorizin is a chemical compound that inhibits the uptake of azide by red blood cells. It has been shown to be effective against intestinal parasites and trophozoites. 4-Aminophlorizin is a potent inhibitor of the membrane system, which may be due to its interaction with the semenza, or membrane protein.</p>

<p>4-O-Acetyl-3,6-di-O-triisopropylsilyl-D-galactal is a modified sugar that can be used as a chiral building block in the synthesis of complex carbohydrates. This product is available for custom synthesis.</p>

<p>Mannitol is a sugar alcohol occurring widely in plants and they are exudates, for example, in olive and plane trees (Collins, 2006). It is produced commercially by the catalytic hydrogenation of fructose (Zelin, 2019). Mannitol is used extensively in food and pharmaceutical industries because of its unique functional properties. It is about 50% as sweet as sucrose and has a desirable cooling effect often used to mask bitter tastes. Mannitol is non-cariogenic and has a low caloric content. Mannitol is an osmotic diuretic that is metabolically inert in humans and is used for: the promotion of diuresis before irreversible renal failure becomes established, the promotion of urinary excretion of toxic substances, as an Antiglaucoma agent, and as a renal function diagnostic aid (O’Neil, 2013). Additonally, in 2020, mannitol was approved by the FDA as add-on maintenance therapy for the control of pulmonary symptoms associated with cystic fibrosis in adult patients (McKenna, 2020).</p>

<p>NGA2FB N-Glycan is a monosaccharide that is synthetically fluorinated on the 2-position of the sugar. It is an oligosaccharide that contains a complex carbohydrate, which is a glycosylation of a polysaccharide with a click modification at the methyl group on the sugar. This product can be custom synthesized to order and offers high purity.</p>

<p>4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is a synthetic, water soluble, non-digestible oligosaccharide. It has regulatory effects on the utilisation of glucose and lacto-n-neotetraose by various cells in vitro. This compound also inhibits the development of intestinal pathogens in humans and elucidates their sequence specificity. 4-O-(b-D-Galactopyranosyl)-D-glucosamine HCl is used to study the role of this molecule in infant nutrition.</p>

<p>3,4,5,6-Tetra-O-acetyl-myo-inositol-1,2-thiocarbonate is a carbohydrate that has been modified with fluorination and methylation. This compound can be used in the synthesis of oligosaccharides, monosaccharides, and glycosylations. 3,4,5,6-Tetra-O-acetyl-myo-inositol is synthesized by reacting myo-inositol with carbon disulfide and sodium hydroxide to form the intermediate methyl ester followed by hydrolysis to produce the final product. The purity of 3,4,5,6-Tetra-O-acetyl-myo-inositol is greater than 98%.</p>

<p>3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O-benzoyl-a-L-fucopyranosyl)-D-galactopyranosyl trichloroacetimidate is a sugar. It is a complex carbohydrate that is a polysaccharide made up of three monosaccharides: D-, L-, and erythro-. This molecule has been fluorinated at the C3 position. The CAS number for this compound is 123787−06−1. 3,4,6-Tri-O-acetyl-2-O-(2,3,4-tri-O--benzoyl--a--L--fucopyranosyl)-D--galactopyranosyl trichloroacetimidate is custom synthesized and has high purity.</p>

<p>1,2,3,4,6-Penta-O-acetyl-a-D-talopyranose is a fluorinated monosaccharide that belongs to the class of synthetic oligosaccharides. It can be used in glycosylation and polysaccharide synthesis. The chemical structure of this compound has been modified by methylation and click chemistry. 1,2,3,4,6-Penta-O-acetyl-a-D-talopyranose is available in high purity and custom synthesis.</p>

Glucobrassicin potassium is a glucosinolate-derived compound, which is a naturally occurring metabolite found in cruciferous vegetables such as broccoli, Brussels sprouts, and cabbage. These compounds are biosynthesized in plant cells and are integral to the plant's defense mechanism against pests and diseases.

<p>Hexa-O-acetylmaltal is a non-reducing sugar that belongs to the class of anhydrous, monohydrate configurations. It is a synthetic substrate that is used in the synthesis of pyridine analogues. Hexa-O-acetylmaltal can be crystallized in chloroform and activated with heat or acid. The anomeric configuration has been determined by X-ray diffraction analysis and its configuration was shown to be anomeric by chemical degradation. Hexa-O-acetylmaltal can also form heptaacetate, which is a disaccharide.</p>

<p>a-Spinasterol glucoside is a glucopyranoside that belongs to the group of triterpenoid. It has a bitter taste, and its chemical structure was first isolated from the seeds of Trichosanthes bracteata. This compound can be found in other plants such as cucurbitacin and cucumeroides. These two compounds are bitter and are used in Chinese traditional medicine for treating inflammation, pain, or even cancer. The chemical structure of a-spinasterol glucoside is related to vanillic acid, glyceryl palmitate, and vanillic acid.</p>

<p>Intermediate in the production of biosynthetic antibiotics</p>

<p>6-O-Tosyl-D-mannose is a Carbohydrate, Modification, saccharide, Oligosaccharide with CAS No. 105265-64-3. It is fluorinated on the 6th carbon atom and methylated on the 3rd carbon atom. It can be used in custom synthesis and also has high purity and a custom synthesis. It can be synthesized by glycosylation or click modification.</p>

<p>The major gel forming component in agar, agarose, consists of a linear chain of sequences of 1,3 linked β-D-galactopyranosyl units and 1,4 linkages to 3,6-anhydro-α-L-galactopyranosyl units. Gelation is done via the formation of double helices (Arnott, 1974). Agar's properties are similar to gelatin as it is primarily used as a plating gel for microbial cultures (Lahaye, 1991). However, agar is a good substitute for animal-based gelatin in vegetarian foods and is easy to use in food gels in a similar way to the carrageenans. Common food applications of agar include: puddings, custards, and soft candies. Agar improves the texture of processed cheese and frozen desserts, and is also added to baked goods to inhibit staling. A creative food application uses agar-based gel cubes that are infused with fruit extract or wine to make a vegetable-based aspic (Armisén, 2009).<br>Agar contains two polysaccharides Agarobiose and Agaropectin. Both Gelidium latifolium and Gelidium amansii are sources of both Agar and Agarose. The images were kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.<br>Agaropectin<br>Agaropectin is a sulphated non-gelling galactan comprising about 30% of Agar. Half ester sulphate is present in varying amounts plus D-glucuronic acid and small amounts of pyruvic acid. As with Agarose the main chain has alternating residues of D-galactose and L-galactose heavily modified with acidic side-groups which are usually sulfate, glucuronate, and pyruvate. Pyruvic acid is possibly attached in an acetal form to the D-galactose residues of the agarobiose skeleton. No formal structure of Agaropectin appears to have been published.<br>Agarose<br>Agarose is a linear gelling polysaccharide of (1-3) linked β-D-galactopyranose residues linked to 3,6-anhydro-α-L-galactopyranose via 1-4 bonds. Agar contains about 60% Agarose.</p>

<p>Varenicline is a glycosylation product with a sugar, which is synthesized by the methylation and fluorination of carbamoyl b-D-glucuronide. This drug is used for the treatment of nicotine dependence in adults. It acts on nicotinic acetylcholine receptors in the brain to reduce cravings and withdrawal symptoms from smoking, as well as increasing the release of dopamine. Varenicline binds to alpha4beta2 nicotinic acetylcholine receptors, which are located in the brain and other organs, such as the stomach and pancreas. The drug has been shown to be effective for smoking cessation when used alone or in combination with nicotine replacement therapy.</p>

<p>6-O-Feruloylsucrose is a phenylpropanoid glycoside that has been shown to inhibit the growth of Gram-positive and Gram-negative bacteria. It is also hepatoprotective and has been shown to have antimicrobial activity against fungi, such as Candida albicans. The 6-O-feruloylsucrose inhibits microbial infections by binding to metal cations, which are essential for bacterial cell wall synthesis. This leads to a decrease in the production of microbial cell walls, inhibiting their growth. 6-O-Feruloylsucrose can be used as an additive in food products or as a preservative in cosmetics.</p>

<p>(R)-Ketoprofen b-D-glucuronide is a synthetic modified sugar that is produced by the glucuronidation of ketoprofen, a nonsteroidal anti-inflammatory drug. The modification of ketoprofen with glucuronic acid can be achieved through an enzymatic process, which is catalyzed by UDP-glucuronyltransferase. This modification increases the solubility of ketoprofen and its ability to penetrate cells. (R)-Ketoprofen b-D-glucuronide has been shown to have antibacterial properties against Gram positive bacteria such as Staphylococcus aureus and Streptococcus pyogenes. It has also shown antiviral activity against HIV-1 due to its inhibition of reverse transcriptase, which is an enzyme important for viral replication.</p>

Methyl 2-acetamido-3-O-(2,3,4,6-tetra-O-acetyl-b-D-galactopyranosyl)-2-deoxy-4,6-O-(4-methoxybenzylidene)-a-D-galactopyranoside is a custom synthesis of an oligosaccharide with a polysaccharide. It is a fluorinated complex carbohydrate that has been modified for high purity. Methyl 2 acetamido 3 O (2,3,4,6 tetra O acetyl b D galactopyranosyl) 2 deoxy 4,6 O (4 methoxybenzylidene) a D galactopyranoside is composed of monosaccharides and sugar.

Ethyl 2,3,6-tri-O-benzyl-1-thio-β-D-galactopyranoside is a synthetic monosaccharide that has been used in the synthesis of oligosaccharides and polysaccharides. It has also been used in glycosylation reactions to produce high purity sugar derivatives. It is a fluorinated sugar molecule that can be custom synthesized to order with a high degree of purity. The CAS number for this compound is 152964-77-7.

<p>Ethyl 4,6-O-(4-methoxybenzylidene)-b-D-thiogalactopyranoside is a custom synthesis of a carbohydrate. It is a high purity product with a purity of at least 99.0%. It has the following properties: Custom synthesis, sugar, Click modification, Fluorination, Glycosylation, Synthetic, Methylation, Modification.<br>This product is registered under CAS No. 100735-66-8 and has the molecular formula C51H75NO17. The molecular weight is 905.1 g/mol and the structural formula is as follows:</p>

<p>2-Acetamido-2-deoxy-4-O-(b-D-galactofuranosyl)-D-glucopyranose is a carbohydrate that belongs to the class of disaccharides. It is a member of the family of b-D-galactofuranosides, which are derived from the hydrolysis of glycosidic linkages in b-D-galactopyranose. 2A2DDG has been shown to interact with sulfate groups and nonreducing sugars. The interaction between 2A2DDG and sulfate groups may be due to the presence of hydroxyl group on the molecule's side chain. The disaccharide can be used as an analogue for glycosylation experiments, such as those involving glycosyltransferases or glycosidases.</p>

3-O-Carboxymethyl-D-glucose (3CMG) is a humectant that can be used to replace glycerol in tobacco. 3CMG has the same chemical formula as D-glucose, but it has a hydroxy group at position 3 instead of 2. This structural difference leads to different properties, such as the ability to form hydrogen bonds with water molecules, which makes it an excellent humectant for use in tobacco products. 3CMG is also used in the food industry as a sugar substitute and sweetener due to its low caloric content and increased sweetness.

<p>Momordicoside I aglycone is a compound that has been extracted from the roots of Momordica grosvenori. It is a potent inhibitor of the enzyme cyclooxygenase and has been shown to have analgesic, anti-inflammatory, and antipyretic activities in mice.</p>

<p>4-Methoxyphenyl 4-O-(2,3,6-tri-O-benzyl-b-D-galactopyranosyl)-2,3,6-tri-O-benzyl-b-D-glucopyranoside is a sugar that is custom synthesized. It is fluorinated and modified with saccharides. The molecular weight of this compound is 582.06 g/mol and the CAS number for it is 15041281.</p>

<p>Main metabolite of antiretroviral drug Abacavir with potent activity against human immunodeficiency virus type 1 (HIV-1). Abacavir is eliminated by hepatic metabolism to two major metabolites: 5’-glucuronide formed by uridine diphosphate glucuronyl transferase and 5’-carboxylate formed by cytosolic alcohol dehydrogenase.</p>

<p>Trimethylsilyl-2,3,4,6-tetra-O-benzyl-b-D-glucopyranoside is a modified carbohydrate that has been fluorinated and silylated. It is used as an intermediate in the synthesis of glycosylated compounds. Trimethylsilyl-2,3,4,6-tetra-O-benzyl-b-D-glucopyranoside can be custom synthesized to meet your needs. It is a white powder that is soluble in water and alcohols. The CAS number for this compound is 89825-08-1.</p>

<p>2,6-Di-O-acetyl-3,4-di-O-benzyl-a-D-mannopyranosyl trichloroactimidate is a synthetic, glycosylate sugar that can be used in the synthesis of oligosaccharides and polysaccharides. This molecule has been fluorinated to increase its lipophilicity and stability. It has been modified with methyl groups to improve its reactivity with other molecules. The purity of 2,6-Di-O-acetyl-3,4-di-O-benzyl-a-D-mannopyranosyl trichloroactimidate is greater than 98%.</p>

<p>Phosphoric acid mono-((2R,3R,4S,5R)-2,3,4,5,7-pentahydroxy-6-hydroxyimino-heptyl) ester disodium salt (compound H) is a high purity compound that can be custom synthesized to suit the customer's needs. It is a synthetically modified sugar with Click modification. This product has been fluorinated and glycosylated. Modification and methylation are also available on request.</p>

<p>1,6-Anhydro-2,3-dideoxy-b-D-threo-hex-2-enopyranose is a carbohydrate that is synthesized from the sugar D-ribose. It can be used as a fluoroquinolone antibiotic. 1,6-Anhydro-2,3-dideoxy-b-D-threohexenopyranose has been modified with fluorine in order to increase its antibacterial activity. This modification makes the compound resistant to bacterial enzymes and allows it to bind to bacterial DNA. 1,6-Anhydro 2,3dideoxy bDthreo hexenopyranose also reacts with sugars and proteins to form glycosides and oligosaccharides that have high purity.</p>

<p>4-Methoxyphenyl 2,4-di-O-benzoyl-3-O-benzyl-6-O-(methyl 5-acetamido-4,7,8,9-tetra-O-acetyl)-3,5-dideoxy--D glycero--alpha--D galacto--2 nonulopyranosylonate) -beta D galactopyranoside is a carbohydrate that is custom synthesized for the modification of saccharides. It has a molecular weight of 1066.81 g/mol and is soluble in water. 4MPB is used as an intermediate for the synthesis of other carbohydrates.</p>

<p>Methyl 2,3,4,6-tetra-O-benzyl-b-D-galactopyranoside is a modification of the sugar galactose. It is a complex carbohydrate and an oligosaccharide that is synthesized from monosaccharides by glycosylation or polysaccharide synthesis. This product has been custom synthesized and can be modified to your specifications. It has high purity and is synthetic. Methyl 2,3,4,6-tetra-O-benzyl-b-D-galactopyranoside is used in various applications such as pharmaceuticals, agrochemicals, cosmetics and food additives.</p>

<p>Pitavastatin 3-O-glucuronide is a synthetic, water soluble glycosylate prodrug of pitavastatin, a third generation HMG-CoA reductase inhibitor. Pitavastatin 3-O-glucuronide has been shown to be effective in lowering serum cholesterol and triglycerides in humans. This drug is metabolized by hydrolysis of the glucuronide moiety and cleavage of the sugar moiety to form active pitavastatin. Pitavastatin 3-O-glucuronide also has an increased stability against oxidation compared to pitavastatin.</p>

<p>O-topolin-9-glucoside is a custom synthesis of a sugar. It can be modified with fluorination, methylation, and click modification. O-topolin-9-glucoside is an oligosaccharide sugar that can be glycosylated or polysaccharided.</p>

<p>(2S- trans)-4-Hydroxy-N-methyl 2-pyrrolidinecarboxamide is a modification of the sugar molecule. It is a complex carbohydrate that belongs to the group of oligosaccharides. It has CAS number 143035-54-5 and can be synthesized in high purity with a glycosylation process. This chemical can also be fluorinated and saccharide substituted to create a wide range of products with different properties.</p>

<p>Pectins are regarded as linear chains of α-1,4-linked D-galacturonic acid, a homogalacturonan (pectic acid). In the products of commerce, the degree of methylation has a vital influence on the properties of pectin, especially the solubility and gel forming characteristics. Commercial high methoxy (HM) pectin has &gt; 70% of hydroxyl groups methyl esterified. HM pectin forms gels in the presence of sucrose and for this reason it is used in jams often in combination with other fruits.</p>

<p>Methyl 2-O-benzoyl-4,6-O-benzylidene-a-D-glucopyranoside is a sugar that is used in the synthesis of complex carbohydrates. This product is custom synthesized and has a purity of greater than 98%. It can be used for Click modifications, fluorination, glycosylation, and synthetic purposes. Methyl 2-O-benzoyl-4,6-O-benzylidene-a-D-glucopyranoside also has CAS No. 28642-64-0.</p>

<p>The 2,3,4-Tri-O-benzoyl-a-L-rhamnopyranosyl fluoride is a complex carbohydrate that is custom synthesized. It is an oligosaccharide and polysaccharide that can be modified with methylation and glycosylation to make it more useful for research purposes. This molecule has been modified with high purity fluorination to increase its stability. Synthetic carbohydrates are used in many different applications such as medical treatments, diagnostic tools, and food additives.</p>

<p>Benzyl b-D-arabinopyranoside is a custom synthesis that can be used in the modification of complex carbohydrates, oligosaccharides, and polysaccharides. This product is a synthetic carbohydrate that can be fluorinated for use as a pharmaceutical or biological agent. It has CAS number 5329-50-0, and can be glycosylated, methylated, or click modified for different applications.</p>

<p>GalNAca1-3(Fuca1-2)Galb1-3GlcNAc</p>

<p>a-L-Fucose-1-phosphate bis(cyclohexylammonium) salt is a synthetic, high purity, custom synthesis that is used for Click modification. It can be synthesized by fluorination and glycosylation of fucose. This product has a CAS No. 24333-03-7, and can be modified with methylation and oligosaccharide. It is used in the production of complex carbohydrates such as saccharides and monosaccharides.</p>