Glycoscience

<p>Fluoxetine D-glucuronide is a glycosylated, fluorinated, custom-synthesized compound. It is composed of the methyl ester and glucuronide moiety of fluoxetine. The synthesis of this compound starts with the oxidation of fluoxetine to form an aldehyde intermediate. This intermediate is then condensed with chloroacetic acid to form the desired product. Fluoxetine D-glucuronide has shown efficacy in animal models for its ability to inhibit serotonin reuptake and block 5HT2A receptors. This drug is also used as a tracer in positron emission tomography (PET) imaging studies for serotonin transporters.</p>

<p>Rhein acyl-b-D-glucuronide is a fluorinated monosaccharide, which can be synthesized from glucose. This product is a complex carbohydrate that is synthesized from glucose and has been modified with methyl groups to provide high purity. It is also an oligosaccharide and can be custom synthesized for your needs. The chemical formula for Rhein acyl-b-D-glucuronide is C6H14O5F2O4.</p>

<p>O-Desmethyl galanthamine b-D-glucuronide is a synthetic carbonyl glycoside. It is an acetylated monosaccharide with a fluorinated sugar. O-Desmethyl galanthamine b-D-glucuronide is prepared by the click modification of N-acetylgalactosamine and D,L-galactose with ethyl diazoacetate in the presence of copper(I) iodide. The methylation of the hydroxyl group on the C2 position of the sugar moiety and glycosylation at the C3 position are also carried out to produce this compound.</p>

<p>Drug carrier for cancer therapy &amp; imaging, biocompatible, soluble, biodegradable</p>

<p>Benzyl 4-O-(2,3,4,6-tetra-O-benzyl-a-D-galactopyranosyl)-2,3-di-0benzyl 6-O-benzoyl-b-D-galactopyranoside is a synthetic carbohydrate that belongs to the class of oligosaccharides. It has been modified by fluorination and methylation. This compound is also glycosylated and click modified.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>1,2,4,6-Tetra-O-acetyl-3-chloro-3-deoxy-D-glucopyranose (1) is a synthetic oligosaccharide that has been modified with a fluorine atom at the 6 position of the glucose moiety. This modification has been shown to have increased stability in acidic environments. Glycosylation can be achieved by reacting 1 with an appropriate glycosylant such as bromoacetyl bromide or chloroacetyl chloride. The saccharide unit may also be methylated at the 2 and 4 positions of the glucose moiety to confer protection against enzymatic degradation. Click modification can be used to attach other molecules such as proteins or peptides to 1,2,4,6-tetra-O-acetyl-3-chloro-3-deoxy--D--glucopyranose via a covalent bond between</p>

<p>2,3,4,6-Tetra-O-benzyl-(+)-1-deoxynojirimycin is a synthetic atypical carbohydrate that has been shown to have anti-hyperglycemic and anti-hyperlipidemic effects. It is a benzylated derivative of the natural product 1-deoxynojirimycin. This compound has been shown to be effective in treating metabolic disorders such as polycystic ovary syndrome and hypercholesterolemia. 2,3,4,6-Tetra-O-benzyl-(+)-1-deoxynojirimycin may act by mimicking the actions of insulin and binding to insulin receptors on cells. This binding prevents the insulin receptor from being phosphorylated by an enzyme called protein kinase A (PKA), thereby inhibiting the action of PKA.</p>

<p>Propranolol is a drug that belongs to the class of beta blockers, which are used to control high blood pressure in women and neonates. Propranolol is metabolized by glucuronidation and hydroxylation into 4'-hydroxypropranolol-4'-O-b-D-glucuronide. The hydroxy group on propranolol is metabolized by hydroxylation in the liver. This metabolic pathway leads to the formation of 4'-hydroxypropranolol-4'-O-b-D-glucuronide, which is excreted through urine samples and plasma concentrations. The hydroxy group on propranolol is also metabolized by glucuronidation, leading to the formation of low bioavailability of propranolol in humans. Propranolol has been shown to inhibit platelet aggregation at higher doses, but its effects on platelet aggregation are not predictable at lower doses.</p>

<p>Trimethylsilyl-meso-inositol is a metabolite of inositol and can be found in biological samples. It has been detected by GC-MS profiling, chromatograms, and profiles. Trimethylsilyl-meso-inositol has been used as an experimental compound to study the effects of electron irradiation on bacterial DNA. This metabolite has also been identified as a volatile substance. There are no known sources or nature of this molecule, but it is reproducible.</p>

<p>N-(e-Aminocaproyl)-a-D-galactopyranosyl amine is a glycosylated, fluorinated, saccharide that is custom synthesized by our company. It can be used as an intermediate in the synthesis of various oligosaccharides and polysaccharides. This product is very soluble in water and can be used for glycosylation reactions. The purity of this product is greater than 99%.</p>

<p>The product is a custom-made synthetic sugar. It is Fluorinated and Methylated. The product has been synthesized for glycosylation, methylation, and click modification. The product can be used in the synthesis of complex carbohydrates.</p>

<p>1-Methylene-5-a-androstan-3-a-ol-17-one glucuronide is a synthetic, modified sugar that is used for the synthesis of complex carbohydrates. It is available in high purity and can be custom synthesized according to customer specifications. 1 Methylene 5 a androstan 3 a ol 17 one glucuronide can be fluorinated, glycosylated, or methylated to meet the needs of different customers. This product has CAS No. 9002-00-6 and is available on request.</p>

<p>1-O-Acetyl-2-deoxy-3,5-di-O-toluoyl-b-D-erythropentofuranose is a monosaccharide that belongs to the group of complex carbohydrates. It is synthetically derived and has been modified with fluorination and acetylation. 1OATBDE is used as a selective labeling agent for glycosyls in glycoconjugates.</p>

<p>1,3,4,6-Tetra-O-acetyl-2-deoxy-2-trifluoroacetamido-D-glucopyranose is a carbohydrate that has been modified with fluorine and acetyl groups. It is used as a precursor to other saccharides. The compound is synthesized by the reaction of 1,3,4,6-tetra -O-acetyl glucose with trifluoroacetic anhydride in methylene chloride. It can be custom synthesized for research purposes. This product has high purity and is sold in both liquid and powder form.</p>

<p>Heparin disaccharide II-H disodium salt is a complex carbohydrate with the chemical formula C3H6Na2O14. It has a molecular weight of 617.8 and a melting point of 204.5°C. The compound has been modified by methylation, glycosylation, fluorination, and click modification. It is a synthetic oligosaccharide with high purity and custom synthesis.</p>

<p>2,3,4-Tri-O-acetyl-D-xylopyranose is a lactide sugar that is found in the cell walls of many plants. It is synthesized from D-xylose by enzymatic condensation with acetylated L-malic acid and has been shown to be biodegradable. 2,3,4-Tri-O-acetyl-D-xylopyranose has been shown to have physical properties that are similar to those of cellulose, such as crystallization and solubility in water. The compound also has an NMR spectrum that contains peaks at δ = 0.8 (triplet), 1.1 (singlet) and 1.5 ppm (doublet). The hydrophobic group on the molecule is thought to contribute to its hydrophilicity.</p>

<p>3-O-Acetyl-1,2-O-isopropylidine-6-O-trityl-a-D-galactofuranose is a synthetic compound with a molecular weight of 514.5. It is an oligosaccharide with a glycosylation modification and fluorination. The compound can be used as a research tool in the study of glycosylation, methylation, click modification, polysaccharide synthesis, fluorination, saccharide modifications and sugar modifications. 3-O-Acetyl-1,2-O-isopropylidine-6-[trityl]-a-[D]galactofuranose can also be used for custom synthesis; this product is available in high purity.</p>

<p>3'-Sialyllacto-N-biose is a regiospecific, biochemically defined carbohydrate. It is a component of the glycan chains that are present on the surface of cell membranes. Lacto-n-biose has been shown to have inhibitory activity against the growth of Mycobacterium tuberculosis and Mycobacterium avium complex bacteria.</p>

<p>N-Benzyl-2,3,4,6-tetra-O-benzyl-1,5-dideoxy-imino-L-iditol is a synthetic oligosaccharide with the formula CH(CH)COH. It can be used in the synthesis of glycosides and polysaccharides. This compound has been shown to have antihypertensive activity.</p>