Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 695 products of "Antiparasitics"
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Clazuril
CAS:Clazuril, Anticoccidial drug, inhibits asexual and sexual stages of Eimeria labbeana/E. columbarum, disrupts life cycle.Formula:C17H10Cl2N4O2Color and Shape:SolidMolecular weight:373.19BTG 502
CAS:BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).Formula:C21H24BrNOPurity:99.30%Color and Shape:SolidMolecular weight:386.33SID 26681509
CAS:SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).Formula:C27H33N5O5SPurity:99.18%Color and Shape:SolidMolecular weight:539.65Ref: TM-T12909
1mg63.00€5mg137.00€10mg205.00€25mg414.00€50mg618.00€100mg882.00€1mL*10mM (DMSO)163.00€Antileishmanial agent-16
CAS:Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) andFormula:C27H37N5O4Purity:98%Color and Shape:SolidMolecular weight:495.61DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurity:97.8% - 99.76%Color and Shape:SolidMolecular weight:495.43Ref: TM-T27135
1mg90.00€5mg253.00€10mg379.00€25mg640.00€50mg892.00€100mg1,224.00€1mL*10mM (DMSO)275.00€Myrrhterpenoid O
CAS:Unfortunately, you did not provide the description of the chemical compound that needs to be rewritten.Formula:C16H20O3Purity:98%Color and Shape:SolidMolecular weight:260.33FIKK9.1-IN-1
CAS:FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,Formula:C22H22N2SePurity:98%Color and Shape:SolidMolecular weight:393.38Antileishmanial agent-23
CAS:Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM.Formula:C20H17N3O4S2Purity:98%Color and Shape:SolidMolecular weight:427.5UCB7362
CAS:UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.Formula:C25H26ClN5O3Purity:97.67%Color and Shape:SolidMolecular weight:479.96Eugenitin
CAS:Eugenitin, a polyketide from Mycoleptodiscus indicus, exhibits inhibitory activity against Leishmania major with an LD50 of 39.9 μM and demonstrates lowFormula:C12H12O4Purity:98%Color and Shape:SolidMolecular weight:220.22Propamidine
CAS:Propamidine acts as a covalent inhibitor of TMPRSS2 and exhibits antibacterial properties. [1]Formula:C17H20N4O2Purity:98%Color and Shape:SolidMolecular weight:312.37Z-Pro-Pro-CHO
CAS:Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01Formula:C18H22N2O4Purity:98%Color and Shape:SolidMolecular weight:330.38Antileishmanial agent-17
CAS:Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.Formula:C27H37N5O5Purity:98%Color and Shape:SolidMolecular weight:511.61ZY-19489
CAS:ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.
Formula:C24H32FN9Purity:>99.99%Color and Shape:SoildMolecular weight:465.57CWHM-1552
CAS:CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.Formula:C22H27F2N3OPurity:99.56%Color and Shape:SolidMolecular weight:387.47GSK3186899
CAS:GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.Formula:C19H28F3N7O3SPurity:98.35% - 99.61%Color and Shape:SolidMolecular weight:491.53Dehydroemetine
CAS:Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.Formula:C29H38N2O4Purity:98.68% - 99.68%Color and Shape:SolidMolecular weight:478.62MMV688533
CAS:MMV688533 has antimalarial activity.Formula:C24H15F6N5O2Purity:99.12%Color and Shape:SoildMolecular weight:519.4Ref: TM-T67695
1mg185.00€5mg409.00€10mg605.00€25mg938.00€50mg1,293.00€100mg1,738.00€500mg3,496.00€1mL*10mM (DMSO)509.00€SLU-10906
CAS:SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.Formula:C22H21BFN5O2Color and Shape:SolidMolecular weight:417.244Arohynapene B
CAS:Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.Formula:C18H22O3Color and Shape:SolidMolecular weight:286.366Antimalarial agent 48
CAS:Antimalarial agent 48 (Compound 15a) is a triazine compound with antimalarial activity, showing effectiveness against Plasmodium falciparum K1 and Plasmodium falciparum FCR3 with IC50 values of 280 and 290 nM, respectively. It holds promise for research in the field of anti-infective treatments.Formula:C19H14F3N11Color and Shape:SolidMolecular weight:453.383MMV03
CAS:MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.Formula:C19H14N4OSColor and Shape:SolidMolecular weight:346.406SAL-0010042
CAS:SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.Formula:C15H15FN4OColor and Shape:SolidMolecular weight:286.304Noracronycine
CAS:Noracronycine is an alkaloid originally isolated from G. pentaphylla, known for its antimalarial activity. It is effective against P. yoelii at a concentration of 10 μg/mL.Formula:C19H17NO3Molecular weight:307.34MED6-189
CAS:MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.Formula:C17H26N2OColor and Shape:SolidMolecular weight:274.40Etofamide
CAS:Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.Formula:C19H20Cl2N2O5Color and Shape:SolidMolecular weight:427.28Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formula:C21H13Cl2F6N5O2SColor and Shape:SolidMolecular weight:584.32WR-27653
CAS:WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.Formula:C20H36BrN3O2Color and Shape:SolidMolecular weight:430.423NEU-1017
CAS:NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.Formula:C33H31ClFN5O3SColor and Shape:SolidMolecular weight:632.147SPB07935
CAS:SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.Formula:C22H15N5O4S2Color and Shape:SolidMolecular weight:477.516PIQ-2
CAS:PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Formula:C23H21F3N4O3Color and Shape:SolidMolecular weight:458.43PFK-IN-1
CAS:PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.Formula:C18H15Cl2N3O4SColor and Shape:SolidMolecular weight:440.3Ferrocene
CAS:Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.Formula:C10H10FeColor and Shape:SolidMolecular weight:186.03Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Formula:C24H32O3Color and Shape:SolidMolecular weight:368.51LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Color and Shape:SolidMolecular weight:377.40Ipronidazole
CAS:Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.Formula:C7H11N3O2Color and Shape:SolidMolecular weight:169.182-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
CAS:Formula:C27H22Cl2N4Purity:98%Color and Shape:SolidMolecular weight:473.3964Chloroquine diphosphate
CAS:Controlled ProductChloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Chloroquine i a schizonticidal agent and is a widely prescribed antimalarial compound. The antiviral activity of chloroquine in vitro has been reported in 1960’s and recent publications have brought attention to its possible benefits in the treatment of COVID-19 patients, infected with the newly emerged coronavirus (SARS-CoV-2). Current evidence shows that chloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the S-glycoprotein.
Formula:C18H32ClN3O8P2Color and Shape:White Off-White PowderMolecular weight:515.86 g/molRef: 3D-FC20382
Discontinued productMebendazole
CAS:Mebendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating intestinal worm infections like threadworms and roundworms.
Formula:C16H13N3O3Purity:99.0 To 101.0%Color and Shape:PowderMolecular weight:295.29 g/molChloroquine sulfate
CAS:Anti-malarial quinine analogue; effective against Covid-19 infection in vitro
Formula:C18H28ClN3O4SPurity:Min. 95%Color and Shape:PowderMolecular weight:417.95 g/molRef: 3D-FC171615
Discontinued productFlubendazole
CAS:Flubendazole is a benzimidazole anthelmintic with action on microtubule formation in parasites and is used for treating intestinal worms in humans and animals.
Formula:C16H12FN3O3Purity:Min. 95%Color and Shape:White PowderMolecular weight:313.28 g/molRef: 3D-FF23317
Discontinued productLevamisole HCl - Bio-X ™
CAS:Levamisole is a synthetic imidazothiazole derivative belonging to the family of anthelmintic drugs. It is a nicotinic acetylcholine receptor (nAChR) agonists that binds to nAChRs on the neuromuscular junctions of parasitic worms, mimicking the action of the neurotransmitter acetylcholine. This excessive stimulation of nAChRs leads to persistent depolarization of muscle cells and spastic paralysis to expel of the worms. Levamisole exhibits broad-spectrum activity against various roundworms, whipworms, hookworms, and threadworms.
Formula:C11H12N2S·HClPurity:Min. 98.0%Color and Shape:PowderMolecular weight:240.75 g/molAmopyroquine
CAS:Amopyroquine is an antimalarial agent and is used for the treatment of malaria. Its mode of action involves the inhibition of haem polymerase in the parasite, leading to the accumulation of toxic haem
Formula:C20H20ClN3OPurity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:353.85 g/molSatranidazole
CAS:Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.
Formula:C8H11N5O5SPurity:Min. 95%Molecular weight:289.27 g/molInsecticidal agent 6
CAS:Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.
Formula:C19H14BrCl2N5O4Purity:98%Color and Shape:SolidMolecular weight:527.16
![2-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00I3TE.webp&w=3840&q=75)
