Antiparasitics
Antiparasitics are compounds designed to treat and prevent parasitic infections by inhibiting the growth and survival of parasites. This category includes a range of antiparasitic agents intended exclusively for laboratory use and not for human consumption. These products are essential for research purposes, allowing scientists to study parasitic life cycles, mechanisms of action, and the development of resistance. The use of antiparasitics in laboratory settings aids in the discovery and optimization of new treatments for parasitic diseases, contributing to advancements in medical and veterinary parasitology. Researchers rely on these products to enhance their understanding of parasitic infections and to develop more effective therapies.
Found 704 products of "Antiparasitics"
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Ivermectin
CAS:<p>Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.</p>Formula:C48H74O14Purity:85%MinMolecular weight:875.1 g/molAmoscanate
CAS:<p>Amoscanate is an antischistosomal agent, which is a synthetic compound with a broad spectrum of activity against parasitic infections. Its mode of action involves the disruption of parasite metabolism and structure, ultimately leading to the elimination of schistosomes. Schistosomes are trematode worms responsible for schistosomiasis, a significant parasitic disease affecting millions of people worldwide.</p>Formula:C13H9N3O2SPurity:Min. 95%Molecular weight:271.3 g/mol4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a
CAS:<p>4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.</p>Formula:C41H60O11Purity:Min. 95%Molecular weight:728.91 g/molICA
CAS:ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).Formula:C13H10N4SPurity:99.68%Color and Shape:SolidMolecular weight:254.31Piperaquine
CAS:<p>Piperaquine is a bisquinoline antimalarial compound and a companion compound to artemisinin.</p>Formula:C29H32Cl2N6Purity:98%Color and Shape:SolidMolecular weight:535.51BPH-715
CAS:<p>BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.</p>Formula:C17H31NO7P2Purity:98.91%Color and Shape:SolidMolecular weight:423.38Quinfamide
CAS:<p>Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.</p>Formula:C16H13Cl2NO4Purity:99.92%Color and Shape:SolidMolecular weight:354.18Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formula:C16H17BrClN3O3·HBrPurity:97.01% - 99.73%Color and Shape:SolidMolecular weight:495.59Antimalarial agent 26
CAS:<p>Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration.</p>Formula:C20H22N4O3Purity:98%Color and Shape:SolidMolecular weight:366.41Antiparasitic agent-18
CAS:<p>Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.</p>Formula:C25H21N7OPurity:98%Color and Shape:SolidMolecular weight:435.48Antimalarial agent 19
CAS:<p>Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.</p>Formula:C22H33Cl2N5SPurity:98%Color and Shape:SolidMolecular weight:470.5Antimalarial agent 24
CAS:<p>Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM</p>Formula:C20H16N4O2Purity:98%Color and Shape:SolidMolecular weight:344.37Antimalarial agent 29
CAS:<p>Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.</p>Formula:C18H10ClF3N2Purity:98%Color and Shape:SolidMolecular weight:346.73Antileishmanial agent-14
CAS:<p>Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by</p>Formula:C23H26ClNO5Purity:98%Color and Shape:SolidMolecular weight:431.91Insecticidal agent 2
CAS:<p>Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].</p>Formula:C16H8ClF7N2O2Purity:98%Color and Shape:SolidMolecular weight:428.69Antileishmanial agent-15
CAS:<p>Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.</p>Formula:C28H39N5O4Purity:98%Color and Shape:SolidMolecular weight:509.64Epsiprantel
CAS:<p>Epsiprantel is an orally active antiparasitic drug that inhibits various tapeworms, including Echinococcus granulosus (granular echinococcus), in dogs.</p>Formula:C20H26N2O2Purity:98.09%Color and Shape:SolidMolecular weight:326.43CRK12-IN-2
CAS:<p>CRK12-IN-2, a potent CRK12 inhibitor, has EC50 of 3.2 nM for T. congolense and 0.08 nM for T. vivax; treats trypanosomiasis in animals.</p>Formula:C23H33F2N5O3S2Purity:99.26% - 99.70%Color and Shape:SolidMolecular weight:529.67Symetine
CAS:Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.Formula:C30H48N2O2Purity:99.79%Color and Shape:SolidMolecular weight:468.71(Rac)-ACT-451840
CAS:<p>(Rac)-ACT-451840 is an isomer of ACT-451840 exhibiting antimalarial activity against Plasmodium falciparum NF54.</p>Formula:C47H54N6O3Purity:99.25%Color and Shape:SolidMolecular weight:750.97
