Protacs and Impurities
m-PEG12-DBCO
m-PEG12-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming …
Formula:
C44H66N2O14
Purity:
98%
Color and Shape:
Solid
Molecular weight:
847
Ref: TM-T18137
2mg | 43.00 € | ||
5mg | 64.00 € | ||
10mg | 93.00 € | ||
25mg | 137.00 € | ||
50mg | 193.00 € | ||
100mg | 314.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC Sirt2 Degrader-1
CAS:2098487-75-1
PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a …
Formula:
C40H40N10O8S2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
852.94
Ref: TM-T16667
100mg | To inquire | ||
500mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
JPS014 TFA
JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class …
Formula:
C48H60F3N7O9S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
968.09
Ref: TM-T77937
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
SIAIS100 TFA
SIAIS100 TFA is a potent BCR-ABL PROTAC degrader, exhibiting a DC50 of 2.7 nM. It …
Formula:
C46H51ClF5N9O7S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1004.46
Ref: TM-T77969
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
JPS016 TFA
JPS016, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I …
Formula:
C50H64F3N7O10S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1012.14
Ref: TM-T77938
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
SJ1008030 TFA
SJ1008030 (compound 8) TFA is a selective JAK2-degrading PROTAC that inhibits the growth of MHH-CALL-4 …
Formula:
C44H44F3N13O9S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
987.96
Ref: TM-T77943
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
CFT1946
CAS:2882165-79-7
CFT1946 is a selective and orally active ligand targeting BRAF kinase, functioning as a degrader …
Formula:
C45H49F2N11O9S
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
958
Ref: TM-T77972
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
BSJ-03-204 triTFA
BSJ-03-204 triTFA is a potent and selective Cereblon- and CDK-targeted PROTAC (PROteolysis TArgeting Chimera) featuring …
Formula:
C49H51F9N10O14
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
1174.97
Ref: TM-T77923
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
TL12-186
CAS:2250025-88-6
TL12-186 is a Cereblon-dependent kinase degrader that degrades CDK, BTK, FLT3, Aurora and other kinases.TL12-186 …
Formula:
C44H51ClN10O9S
Purity:
98.2%
Color and Shape:
Solid
Molecular weight:
931.46
Ref: TM-T34888
1mg | 112.00 € | ||
5mg | 269.00 € | ||
10mg | 449.00 € | ||
25mg | 831.00 € | ||
50mg | 1,136.00 € | ||
100mg | 1,537.00 € | ||
1mL*10mM (DMSO) | 463.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
MS4077
CAS:2230077-10-6
MS4077 is an degrader of anaplastic lymphoma kinase (ALK) PROTAC(Kd of 37 nM for binding …
Formula:
C55H72ClN9O13S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1134.73
Ref: TM-T13781
5mg | 822.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
XY028-133
CAS:2229974-73-4
XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.
Formula:
C53H67N11O7S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1002.23
Ref: TM-T13361
1mg | 115.00 € | ||
5mg | 278.00 € | ||
10mg | 488.00 € | ||
25mg | 827.00 € | ||
50mg | 1,476.00 € | ||
100mg | 2,467.00 € | ||
1mL*10mM (DMSO) | 545.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC CDK2/9 Degrader-1
CAS:2408641-24-5
PROTAC CDK2/9 Degrader-1 is a potent CDK2 and CDK9 dual degrader(DC50 of 62 nM and …
Formula:
C40H41N13O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
815.84
Ref: TM-T12552
100mg | To inquire | ||
500mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
MS432
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.
Formula:
C50H65F3IN7O6S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1076.06
Ref: TM-T13782
100mg | To inquire | ||
500mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
CP-10
CAS:2366268-80-4
CP-10, a selective PROTAC, degrades CDK6 (DC50: 2.1 nM) and inhibits hematopoietic cancers, including multiple …
Formula:
C44H49N13O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
871.94
Ref: TM-T13627
5mg | 687.00 € | ||
10mg | 940.00 € | ||
50mg | 2,067.00 € | ||
100mg | To inquire | ||
200mg | To inquire | ||
1mL*10mM (DMSO) | 998.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC K-Ras Degrader-1
CAS:2378258-52-5
PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.
Formula:
C53H62N10O10
Purity:
98%
Color and Shape:
Solid
Molecular weight:
999.12
Ref: TM-T13844
1mg | 431.00 € | ||
5mg | 1,171.00 € | ||
10mg | 1,878.00 € | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
YX-2-107
CAS:2417408-46-7
YX-2-107: CDK6-degrading PROTAC, IC50 of 4.4 nM, hinders RB phosphorylation/FOXM1, counters Ph+ ALL growth in …
Formula:
C45H51N11O9
Purity:
98.09%
Color and Shape:
Liquid
Molecular weight:
889.95
Ref: TM-T74710
1mg | 210.00 € | ||
5mg | 523.00 € | ||
10mg | 838.00 € | ||
25mg | 1,551.00 € | ||
50mg | 2,311.00 € | ||
100mg | 3,118.00 € | ||
1mL*10mM (DMSO) | 584.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
DB1113
CAS:2769753-53-7
DB1113 is a bifunctional kinase degrader, targeting ABL1, ABL2, CDK4, MAPKs, and more for disease …
Formula:
C59H68F3N13O6S
Color and Shape:
Liquid
Molecular weight:
1144.31
Ref: TM-T74642
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
OARV-771
CAS:2683008-37-7
OARV-771: VHL-based PROTAC targeting BET; DC50: Brd4-6nM, Brd2-1nM, Brd3-4nM; enhanced cell permeability.
Formula:
C49H59ClN8O8S2
Color and Shape:
Liquid
Molecular weight:
987.62
Ref: TM-T74391
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
MTX-23
CAS:2488296-74-6
MTX-23, an AR-targeted Proteolysis Targeting Chimera (PROTAC), effectively degrades both AR-V7 and AR-FL, inhibiting the …
Formula:
C43H53F2N7O7S2
Color and Shape:
Liquid
Molecular weight:
882.05
Ref: TM-T74744
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
ARD-61
CAS:2316837-08-6
ARD-61: potent PROTAC, degrades AR/PR in AR+ cancers, triggers apoptosis, inhibits tumor growth in mice.
Formula:
C61H71ClN8O7S
Color and Shape:
Solid
Molecular weight:
1095.8
Ref: TM-T39853
25mg | 1,422.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024