Protacs and Impurities
PROTAC GPX4 degrader-1
CAS:2916433-81-1
PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation …
Formula:
C50H57ClN10O10
Color and Shape:
Liquid
Molecular weight:
993.5
Ref: TM-T74796
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
SIM1
SIM1, a potent PROTAC®Degrader, preferentially degrades BET proteins (BRD4, BRD2, BRD3) and induces apoptosis in …
Ref: TM-T41226
5mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
PROTAC PD-L1 degrader-2
PROTAC PD-L1 degrader-2, an orally administered compound, targets HPK1 and boosts the efficacy of PD-L1 …
Formula:
C43H42N8O5
Color and Shape:
Liquid
Molecular weight:
750.84
Ref: TM-T200313
10mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
CPS2
CAS:2756741-90-7
CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.
Formula:
C38H42N12O10S2
Color and Shape:
Liquid
Molecular weight:
890.94
Ref: TM-T74181
5mg | 455.00 € | ||
10mg | 834.00 € |
Estimated delivery in United States, on Tuesday 3 Dec 2024
ARD-69
ARD-69, a potent PROTAC, degrades AR in prostate cancer, with low DC50 values in AR+ …
Formula:
C62H74ClFN8O7S
Color and Shape:
Solid
Molecular weight:
1129.83
Ref: TM-T30123
100mg | To inquire | ||
500mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
HD-TAC7
HD-TAC7 is a PROTAC HDAC degrader; IC50s: HDAC1 (3.6μM), HDAC2 (4.2μM), HDAC3 (1.1μM); reduces NF-κB …
Formula:
C33H32FN7O7
Color and Shape:
Liquid
Molecular weight:
657.65
Ref: TM-T74514
5mg | To inquire | ||
50mg | To inquire |
Estimated delivery in United States, on Tuesday 3 Dec 2024
TCO-PEG4-NHS ester
CAS:1613439-69-2
TCO-PEG4-NHS ester is a PROTAC linker bridge belonging to the PEG class.TCO-PEG4-NHS ester can be …
Formula:
C24H38N2O10
Purity:
99.75%
Color and Shape:
Solid
Molecular weight:
514.57
Ref: TM-T17017
5mg | 66.00 € | ||
10mg | 94.00 € | ||
25mg | 185.00 € | ||
50mg | 291.00 € | ||
100mg | 460.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Methyltetrazine-Amine
CAS:1345955-28-3
Methyltetrazine-Amine is a methyl-substituted tetrazine amine used in the synthesis of PROTAC molecules.
Formula:
C10H11N5
Purity:
97.59%
Color and Shape:
Pink Solid
Molecular weight:
201.23
Ref: TM-T20967
5mg | 42.00 € | ||
10mg | 58.00 € | ||
25mg | 110.00 € | ||
50mg | 167.00 € | ||
100mg | 271.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
LC-2
CAS:2502156-03-6
LC-2 (PROTAC KRASG12C Degrader-LC-2) is a novel von Hippel-Lindau-based PROTAC degrader of endogenous KRAS G12C …
Formula:
C59H71ClFN11O7S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
1132.78
Ref: TM-T36256
1mg | 247.00 € | ||
5mg | 617.00 € | ||
50mg | To inquire |
Estimated delivery in United States, on Thursday 5 Dec 2024
PROTAC CDK9 Degrader-1
CAS:2118356-96-8
PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.
Formula:
C33H35N5O7
Purity:
98%
Color and Shape:
Solid
Molecular weight:
613.66
Ref: TM-T5438
1mg | 125.00 € | ||
5mg | 307.00 € | ||
10mg | 503.00 € | ||
1mL*10mM (DMSO) | 423.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Diazo Biotin-PEG3-alkyne
CAS:1884349-58-9
Diazo Biotin-PEG3-alkyne is a PROTAC linker belonging to the PEG class and can be used …
Formula:
C39H53N7O9S
Purity:
98%
Color and Shape:
Solid
Molecular weight:
795.95
Ref: TM-T15114
1mg | 78.00 € | ||
5mg | 167.00 € | ||
10mg | 265.00 € | ||
25mg | 448.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
KT-474
CAS:2432994-31-3
KT-474 (KYM-001) is a PROTAC degrader targeting IRAK4 with antitumor activity for the study of …
Formula:
C44H49F2N11O6
Color and Shape:
Liquid
Molecular weight:
865.93
Ref: TM-T74411
1mg | 234.00 € | ||
5mg | 595.00 € | ||
10mg | 838.00 € | ||
25mg | 1,220.00 € | ||
50mg | 1,674.00 € | ||
100mg | 2,260.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Benzyl-PEG12-alcohol
CAS:2218463-17-1
Benzyl-PEG12-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming …
Formula:
C31H56O13
Purity:
≥98%
Color and Shape:
Liquid
Molecular weight:
636.77
Ref: TM-T39689
1mg | 55.00 € | ||
5mg | 64.00 € | ||
10mg | 93.00 € | ||
25mg | 125.00 € | ||
50mg | 168.00 € | ||
100mg | 244.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
JET-209
JET-209 is a potent proteolysis-targeting chimera (PROTAC) that effectively degrades CBP/p300, exhibiting half-maximal degradation concentration …
Formula:
C46H47N9O6
Purity:
98%
Color and Shape:
Liquid
Molecular weight:
821.92
Ref: TM-T79230
1mg | 712.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
PROTAC EZH2 Degrader-1
CAS:2641601-67-2
PROTAC EZH2 Degrader-1 inhibits EZH2 enzyme, crucial in cancer, with an IC50 of 2.7 nM.
Formula:
C54H67N7O8
Color and Shape:
Liquid
Molecular weight:
942.15
Ref: TM-T74602
1mg | 199.00 € | ||
5mg | 596.00 € | ||
10mg | 901.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
FKBP12 PROTAC RC32
CAS:2375555-66-9
FKBP12 PROTAC RC32 is a PROTAC-like degrader targeting FKBP12. It can degrade FKBP12 in organs …
Formula:
C75H107N7O20
Purity:
98.57% - 99.57%
Color and Shape:
Solid
Molecular weight:
1426.69
Ref: TM-T13694
1mg | 196.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
BI-3663
CAS:2341740-84-7
BI-3663 is a selective PTK2/FAK PROTAC with cereblon ligands, degrading PTK2 (IC50: 18 nM), and …
Formula:
C44H42F3N7O12
Purity:
98%
Color and Shape:
Solid
Molecular weight:
917.84
Ref: TM-T17543
1mg | 180.00 € | ||
5mg | 473.00 € | ||
10mg | 889.00 € |
Estimated delivery in United States, on Thursday 5 Dec 2024
Ref: 4Z-P-346004
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024
ARV-825
CAS:1818885-28-7
ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.
Formula:
C46H47ClN8O9S
Purity:
97.54% - 98%
Color and Shape:
Solid
Molecular weight:
923.43
Ref: TM-T5434
1mg | 65.00 € | ||
5mg | 142.00 € | ||
10mg | 171.00 € | ||
25mg | 248.00 € | ||
50mg | 346.00 € | ||
100mg | 517.00 € |
Estimated delivery in United States, on Tuesday 10 Dec 2024
Ref: 4Z-P-346005
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Estimated delivery in United States, on Tuesday 10 Dec 2024