DNA Cross Linkers
Found 618 products of "DNA Cross Linkers"
Procarbazine hydrochloride
CAS:Formula:C12H19N3O·HClPurity:98.0 - 102.0 % (dried basis)Color and Shape:White to off-white powderMolecular weight:257.76Bendamustine hydrochloride
CAS:Formula:C16H21Cl2N3O2·HCl·xH2OPurity:≥ 98.0%Color and Shape:White to yellow crystalline powderMolecular weight:394.72 (anhydrous)Melphalan
CAS:Formula:C13H18Cl2N2O2Purity:≥ 95.0%Color and Shape:White, off-white or pale yellow powderMolecular weight:305.204-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid Salt
CAS:Controlled ProductApplications A sulfhydryl and carbohydrate reactive, heterobifunctional crosslinking reagent. Glycoprotein reactive.
References Yoshitake, S., et al.: Eur. J. Biochem., 101, 395 (1979), Chamow, S.M., et al.: J. Biol. Chem., 267(22), 15916 (1992)Formula:C12H17N3O3·C2HF3O2Color and Shape:NeatMolecular weight:365.3Deoxypyridinoline Chloride Trihydrochloride Salt
CAS:Controlled ProductStability Hygroscopic
Applications Deoxypyridinoline Chloride Trihydrochloride Salt a collagen cross-links agent. A primary reference material for the monitoring of bone metabolism.
References Heaney, R., et al.: J. Bone Miner. Res., 5, 1135 (1990), Hannon, R., et al.: J. Bone Miner. Res., 13, 1124 (1998), Coudray, C., et al.: Eur. J. Nutr., 42, 91 (2003), Abrams, S., et al.: Am. J. Clin. Nutr., 82, 471 (2005),Formula:C18H28N4O7·HClColor and Shape:NeatMolecular weight:448.899N-Biotinylcaproylaminocaproylaminoethyl Methanethiosulfonate
CAS:Controlled ProductStability Moisture Sensitive
Applications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease.
References Wagner, D.A.and Czajkowski, C.: J. Neurosci., 21, 67 (2001), Traebert, M.: J. Membr. Biol., 180, 83 (2001)Formula:C25H45N5O6S3Color and Shape:NeatMolecular weight:607.85Fluorescein 5-Maleimide (90%)
CAS:Controlled ProductApplications Fluorescent labeling reagent for proteins and peptides.
References Vives, E. and Lebleu, B. : Tetrahedron Letters, 44, 5389 (2003), Li, J., et al.: Bioorg. Med. Chem. Lett., 15, 5558 (2005), Oejmeyr, L., et al.: Biochemi., 48, 2173 (2009),Formula:C24H13NO7Purity:90%Color and Shape:NeatMolecular weight:427.36Benzophenone-4-carboxamidoethyl Methanethiosulfonate
CAS:Formula:C17H17NO4S2Color and Shape:NeatMolecular weight:363.45(2S,2’S,5S)-5-Hydroxy Lysinonorleucine
CAS:Stability Hygroscopic
Applications 2S,2’S,5S)-5-Hydroxy Lysinonorleucine is one of the stereoisomers of 5-Hydroxylysinonorleucine, reduced collagen cross links.
References Astbury, C., et al.: Br. J. Rheumatol., 33, 11 (1994), Watts, N., et al.: Clin. Chem., 45, 1359 (1999), Banse, X., et al.: Bone, 31, 70 (2002),Formula:C12H25N3O5Color and Shape:Light Orange to Brown SolidMolecular weight:291.342-(Triethylammonium)ethyl Methanethiosulfonate Bromide
CAS:Controlled ProductStability Water Sensitive
Applications A water soluble, bulkier analogue of the charged MTS reagent MTSET. Charged MTS reagents have been used successfully with SCAM (substituted cysteine accessibility method) to probe the topology and function of a number of ligand-gated ion channels and transporter proteins.Formula:C9H22BrNO2S2Color and Shape:NeatMolecular weight:320.31S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine
CAS:Controlled ProductFormula:C14H13N5O2S2Color and Shape:NeatMolecular weight:347.42PNU 159682
CAS:DNA alkylating agent; highly potent metabolite of nemorubicinFormula:C32H35NO13Purity:Min. 90 Area-%Color and Shape:Red PowderMolecular weight:641.62 g/molTemozolomide - Bio-X ™
CAS:Temozolomide is an imidazotetrazine alkylating agent. It has anti-tumor activity against a broad spectrum of tumors, such as leukemias, lymphomas and solid tumors. Temozolomide induces G2/M arrest, preventing cells from entering mitosis and, therefore, apoptosis. As a drug resistance-modifying agent it is used for studying drug resistance mechanisms in glioblastoma cell lines.
Formula:C6H6N6O2Purity:Min. 98 Area-%Color and Shape:White To Pale Pink SolidMolecular weight:194.15 g/molCarmustine - Bio-X ™
CAS:Carmustine is a DNA alkylating agent which also cross-links DNA. As a result, Carmustine disrupts the function of DNA, resulting in the arrest the cell cycle and apoptosis. Consequently these properties of Carmustine, in addition to its ability to easily transmit through the blood-brain barrier, means it can be used as a cancer treatment, treating cancers such as, breast, ovarian and pancreatic as well as lymphomas and leukemias. Furthermore Carmustine can contribute to cytotoxic effects through its ability to carbamoylate DNA repair enzymes and proteins.Formula:C5H9Cl2N3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:214.05 g/molLomustine - Bio-X ™
CAS:Lomustine is an alkylating agent that is used as chemotherapy for treating metastatic brain tumors and relapsed Hodgkin’s disease in combination with radiation treatments. This drug causes alkylation and cross-linking of DNA, thus inducing cytotoxicity. Furthermore, this drug inhibits DNA synthesis.
Formula:C9H16ClN3O2Purity:Min. 95%Color and Shape:PowderMolecular weight:233.7 g/molProcarbazine HCl - Bio-X ™
CAS:Procarbazine is an alkylating agent used in chemotherapy to treat brain cancer and Hodgkin's lymphoma. It methylates guanine in DNA which causes the strands to become prone to breakage, thus inhibiting both DNA and RNA synthesis. The drug has been shown to be effective in vitro against a variety of human carcinoma cell lines.Formula:C12H20ClN3OPurity:Min. 95%Color and Shape:PowderMolecular weight:257.76 g/molCarboplatin - Bio-X ™
CAS:Carboplatin is an antineoplastic alkylating agent that is used in the treatment of ovarian cancer. This drug attaches alkyl groups to nucleotides leading to the formation of monoadducts. Carboplatin’s main mechanism of action is preventing DNA strands from separating for synthesis and transcription.Formula:C6H12N2O4PtPurity:Min. 95%Color and Shape:PowderMolecular weight:371.25 g/molEptaplatin
CAS:Platinum-based anti-tumor drugFormula:C11H20N2O6PtPurity:Min. 95%Color and Shape:PowderMolecular weight:471.37 g/molBendamustine HCl - Bio-X ™
CAS:Bendamustine is a bifunctional mechlorethamine derivative with alkylator and antimetabolite properties. An alkylating group, a benzimidazole ring that may function as a purine analog, and a butyric acid side chain are the three active moieties found in bendamustine. Through its function as an alkylating agent, Bendamustine causes intra and inter-strand crosslinks between DNA bases resulting in DNA, RNA synthesis inhibition and cell death.Formula:C16H21Cl2N3O2•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:394.72 g/mol
![S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FA859000.webp&w=3840&q=75)
