Backbone Sugars and Nucleobases

Applications Used in the preparation of pyrrolotriazines.

Applications N2-Acetyl-O6-diphenylcarbamoylguanine is a reactant in the synthesis of 1',2'-oxetane-nucleosides bearing 2'-C-Me substituents with anti-HCV activity.
References Komsta, Z., et. al.: Tetrahedron Lett., 55, 6216 (2014)

Applications 6-Chloro-7-deazaguanine (cas# 84955-31-7) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications 2,4-Dithiouridine (cas# 13239-96-8) is a compound useful in organic synthesis.

Applications 4-Amino-1,3-dimethyl-5-nitrosouracil is a useful building block for organic synthesis.

Applications 6-Amino-5-nitrouracil (cas# 3346-22-3) is a compound useful in organic synthesis.
References Graves, A., et al.: J. Mol. Biol., 377, 914 (2008),

Applications 5-O-Trityl-2,3’-anhydrothymidine (cas# 25442-42-6) is a compound useful in organic synthesis.

Applications 6-Amino-1,3-dimethyl-5-nitrosouracil (cas# 3346-61-0) is a compound useful in organic synthesis.
References Varma, R., et al.: J. Ocular Pharmacol. Ther., 16, 571 (2000),

Applications Tris(trimethylsilyl)guanine is an intermediate used in the synthesis of 9-(2-Hydroxyethyl)guanine (H942035), which is an impurity of the antiviral agent Acyclovir (A192400). 9-(2-Hydroxyethyl)guanine is a nucleoside phosphotransferase acceptor.
References Kamimura, A. et al.: Agric. Biol. Chem., 37, 2037 (1973);

Stability Hygroscopic
Applications 6-Azauridine is can be applied in antiviral studies.

Applications A DNA adduct ethylene oxide hydroxyethylnitrosourea. It is also used in the preparation of acyclic nucleosides and nucleotides as antiviral agents.
References Snoeck, R., et al.: Antimicrob. Agents Chemother., 32, 1839 (1988), Bronson, J., et al.: J .Med. Chem., 32, 1457 (1989), Balzarini, J., et al.: J. Biol. Chem., 266, 8686 (1991),

Applications 5,6-Diaminouracil sulfate is an intermediate in the synthesis of Paraxanthine (P192500) and Paraxanthine analogs.
References Mueller, C.E., et al.: J. Med. Chem., 36, 3341 (1993),

Applications Adenosine analog
References Barbieri, D., et al.: Bioorg. Med. Chem. Lett., 8, 2533 (1998),

Applications 7-Deazaguanine (cas# 7355-55-7) is a compound useful in organic synthesis.

Applications N4-Aminocytidine (cas# 57294-74-3) is a useful research chemical.