Backbone Sugars and Nucleobases
Found 1002 products of "Backbone Sugars and Nucleobases"
8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine
CAS:Controlled Product8-Methoxymethyl-1-methyl-3-(2-methylpropyl) xanthine (8MMX) is an intracellular calcium ion chelator that inhibits enzyme activity in the cyclic nucleotide phosphodiesterase enzyme family. 8MMX has been shown to be a potent inhibitor of both cyclic nucleotide phosphodiesterases and cyclic nucleotide phosphodiesterase isoenzymes. 8MMX has been shown to inhibit bladder contractility and improve bladder function in animal models. It also reduces the incidence of papillary muscle rupture, which can lead to heart failure, and improves ventricular function by increasing the rate of relaxation of the left ventricle. 8MMX is a potential treatment for pulmonary hypertension, which is caused by increased concentrations of intracellular calcium ions.Formula:C12H18N4O3Purity:Min. 95%Molecular weight:266.3 g/mol(E)-5-(2-Bromovinyl)uracil
CAS:(E)-5-(2-Bromovinyl)uracil is a drug that has been shown to be effective against leukemic cells. It is a prodrug of 5-bromouracil, which is an antimetabolite and cytotoxic agent. (E)-5-(2-Bromovinyl)uracil has also been shown to be active against solid tumours, such as metastatic colorectal cancer, and bacteria. The mechanism of action involves the irreversible inhibition of the enzyme thymidylate synthase, which catalyzes the conversion of deoxyuridine monophosphate (dUMP) to thymidine monophosphate (dTMP). The drug binds to the dinucleotide phosphate pocket in the enzyme's active site and blocks access by dUMP. This leads to DNA synthesis errors, causing cell death. As a prodrug, it has low toxicity profiles and does not cause bone marrow suppression likeFormula:C6H5BrN2O2Purity:(¹H-Nmr) Min. 95 Area-%Color and Shape:Off-white to pale orange solid.Molecular weight:217.02 g/molN6-Methyladenine
CAS:N6-Methyladenine is a modification of adenine in DNA. It is formed by the methylation of the N6 position of adenine, which is a group P2 purine base. The structural analysis of this compound has been studied using x-ray diffraction data, and it has been found that it may inhibit cancer cells by modifying their DNA. This compound can also be used as an antimicrobial agent to treat infections caused by eukaryotes such as bacteria and fungi. N6-Methyladenine may be useful in transcriptional regulation and cellular transformation.
Formula:C6H7N5Purity:Min. 95%Color and Shape:PowderMolecular weight:149.15 g/mol9-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione
CAS:Controlled ProductPlease enquire for more information about 9-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C10H11N7O2SPurity:Min. 95%Molecular weight:293.31 g/mol3-Methyl-7-(5-oxohexyl)-1-propylxanthine
CAS:Controlled ProductPlease enquire for more information about 3-Methyl-7-(5-oxohexyl)-1-propylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C15H22N4O3Purity:Min. 95%Molecular weight:306.36 g/mol1-(3-Carboxypropyl)-3,7-dimethylxanthine
CAS:Controlled Product1-(3-Carboxypropyl)-3,7-dimethylxanthine is a drug that belongs to a class of drugs called multidrugs. It has been shown to inhibit the growth of endothelial cells by blocking the binding of tnf-α to its receptor on these cells. 1-(3-Carboxypropyl)-3,7-dimethylxanthine also inhibits cancer cell proliferation and has been shown to be effective in some human cancer models. This drug interacts with other molecules (e.g., proton) and can have significant effects on magnetic resonance spectroscopy assays as well as in humans.Formula:C11H14N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:266.25 g/mol1-Allyl-3,7-dimethyl-8-phenylxanthine
CAS:Controlled ProductPlease enquire for more information about 1-Allyl-3,7-dimethyl-8-phenylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C16H16N4O2Purity:Min. 95%Molecular weight:296.32 g/mol1-(Ethyl-3-carboxypropyl)-3,7-dimethylxanthine
CAS:Controlled ProductPlease enquire for more information about 1-(Ethyl-3-carboxypropyl)-3,7-dimethylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C13H18N4O4Purity:Min. 95%Molecular weight:294.31 g/mol8-Cyclopentyl-1,3-dimethylxanthine
CAS:Controlled Product8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a xanthine derivative that binds to the adenosine receptor and inhibits the phosphodiesterase enzyme. CPT is used in vivo as a model for measuring locomotor activity, dopamine receptors, adenosine receptors, and glutamate receptors. The binding of CPT to these receptors can lead to bronchoconstriction by stimulating the release of vasoactive substances from airway cells and increasing the sensitivity of airway cells to bronchoconstrictor stimuli. This drug also has been shown to inhibit calcium ion influx into cytosol and increase intracellular levels of cAMP.
Formula:C12H16N4O2Purity:Min. 95%Color and Shape:PowderMolecular weight:248.28 g/mol8-[(2-Hydroxyethyl)(methyl)amino]-1,3,9-trimethyl-3,9-dihydro-1H-purine-2,6-dione
CAS:Controlled ProductPlease enquire for more information about 8-[(2-Hydroxyethyl)(methyl)amino]-1,3,9-trimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C11H17N5O3Purity:Min. 95%Molecular weight:267.28 g/mol6-Amino-5-nitroso-2-thiouracil
CAS:6-Amino-5-nitroso-2-thiouracil is a water molecule that has been synthesized and characterized by the kinetic method. It has an intense absorption line at 514 nm and can be used as a marker for technetium. 6-Amino-5-nitroso-2-thiouracil is also a ligand, which is a chemical that binds to metal ions in order to form coordination complexes. 6-Amino-5-nitroso-2-thiouracil is formed by the reaction of chloramine with ammonia, as well as other reactions involving chlorine atoms. 6Amino - 5 nitroso - 2 thiouracil can be used as a chelate ring, which is a type of ligand that contains both nitrogen and sulfur atoms. Bleomycin, a five membered ring molecule, reacts with 6 amino - 5 nitroso - 2 thiouracil toFormula:C4H4N4O2SPurity:Min. 95%Molecular weight:172.17 g/mol1-(2,3-Dihydroxypropyl)-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione
CAS:Controlled Product1-(2,3-Dihydroxypropyl)-3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione (theophylline) is a bronchodilator and anti-inflammatory agent. It is used to treat asthma and other respiratory conditions. Theophylline is structurally similar to caffeine and theobromine and has been shown to have a similar effect on the heart and blood vessels as these stimulants. It also stimulates the central nervous system in a manner similar to that of theobromine. Theophylline has shown some benefit in congestive heart failure patients but has not been proven effective for treating high blood pressure or fibrillation.Formula:C10H14N4O4Purity:Min. 95%Molecular weight:254.24 g/mol8-Aminoguanine
CAS:8-Aminoguanine is an anti-cancer agent that is used to treat leukemia. It is a hydrophobic molecule with a redox potential of −0.20 V and has been shown to inhibit the enzyme ribonucleotide reductase in vitro and in vivo. 8-Aminoguanine inhibits the production of guanine nucleotides, which are necessary for DNA synthesis and cell division. This drug also has angiogenic properties, which may be due to its ability to stimulate the formation of new blood vessels by increasing nitric oxide synthase activity. 8-Aminoguanine has also been shown to improve congestive heart failure by reducing myocardial fibrosis and ventricular hypertrophy through activation of the glycosidic bond cleavage system.
Formula:C5H6N6OPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:166.14 g/mol7-Benzyl-1H-Purine-2,6(3H,7H)-Dione
CAS:Controlled ProductPlease enquire for more information about 7-Benzyl-1H-Purine-2,6(3H,7H)-Dione including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C12H10N4O2Purity:Min. 95%Molecular weight:242.23 g/mol6-Amino-1-methyl-5-nitrosouracil
CAS:6-Amino-1-methyl-5-nitrosouracil is a neutral form of the molecule that has both protonated and unprotonated forms. It is a bidentate ligand that can bind to a metal ion. The nitrogen atom in the molecule is an important part of its structure, as it contains two nitro groups and one amino group. 6-Amino-1-methyl-5-nitrosouracil has been used in techniques such as spectroscopies and dinitroso analysis. The neutral form of the molecule can be converted into its ionic form by adding either chlorine or nitrate ions to it, which causes the nitrogen atoms to be more electronegative. This conversion changes the nature of the compound, making it more acidic. Dehydration also occurs when water molecules are removed from 6-amino 1 methyl 5 nitrosourea, which causes a change in shape and shifts its properties to
Formula:C5H6N4O3Purity:Min. 95%Molecular weight:170.13 g/mol5-Amino-3,7-dimethylxanthine
CAS:Controlled ProductPlease enquire for more information about 5-Amino-3,7-dimethylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C7H9N5O2Purity:Min. 95%Molecular weight:195.18 g/molDye 937
CAS:Dye 937 is substituted unsymmetrical cyanine dyes and useful in the detection of DNA in electrophoretic gels.Formula:C32H37IN4SPurity:98%Color and Shape:SolidMolecular weight:636.638-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,9-dihydro-1H-purine-2,6-dione
CAS:Controlled ProductPlease enquire for more information about 8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C19H22N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:370.4 g/molAdenine sulfate dihydrate
CAS:Adenine sulfate dihydrate is an important component of the energy-producing process in mitochondria. Adenine sulfate dihydrate is a necessary cofactor for many metabolic reactions, including those that produce ATP and NADH. It has been shown to promote growth factor activity and stimulate cell proliferation. Adenine sulfate dihydrate can be used as a nutrient solution in recombinant protein production, where it is required for the expression of recombinant proteins in E. coli or mammalian cells. This compound also plays an important role in the glycosylation of proteins during their synthesis on ribosomes and may have implications for protein folding and stability.Formula:(C5H5N5)2•(H2O)2•H2SO4Purity:Min. 95%Color and Shape:PowderMolecular weight:404.36 g/molCytosine
CAS:Pyrimidine nucleobase; component of nucleic acidsFormula:C4H5N3OPurity:(Hplc) Min. 99%Color and Shape:White PowderMolecular weight:111.1 g/mol
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