Backbone Sugars and Nucleobases
Backbone sugars and nucleobases are essential components of nucleic acids such as DNA and RNA. The backbone consists of sugar and phosphate groups, while nucleobases form the genetic code through base pairing. These compounds are crucial in the study of genetics and molecular biology. At CymitQuimica, you can find a variety of backbone sugars and nucleobases for research and laboratory use.
Found 1003 products of "Backbone Sugars and Nucleobases"
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9-(beta-D-Xylofuranosyl)guanine
CAS:9-(β-D-xylofuranosyl)guanine (9XG) is a trifluoride. It is an antiviral agent that inhibits the growth of herpes virus, in particular by methylating guanosine to 9-methylguanosine in the viral DNA. 9XG binds to the viral DNA and prevents its replication through the inhibition of RNA synthesis. The drug is active against many different types of viruses and has been shown to be effective against tissue cultures infected with herpes virus. 9XG is synthesized from guanosine and boron trifluoride etherate, which are reacted at -78 degrees Celsius for three days. This yields a mixture of compounds with various peracylation groups, which are then separated by chromatography.
Purity:Min. 95%2-Mercaptopurine
CAS:2-Mercaptopurine (2MP) is a thiopurine drug that is used to treat bowel disease. 2MP inhibits the activity of methyltransferase, which is an enzyme that converts 6-mercaptopurine to 6-thioguanine. This process prevents the conversion of 6-thioguanine into 6-thiouric acid, which is an intermediate in the synthesis of thymine nucleotides. 2MP also inhibits the binding of atp-binding cassette transporter proteins to DNA and blocks the incorporation of purines into RNA and DNA. The drug has been shown to be effective in treating squamous cell carcinoma and other diseases with a high level of activity. 2MP has been shown to be metabolized by erythrocyte polymerase chain reaction and can be detected in biological samples.Formula:C5H4N4SPurity:Min. 95%Color and Shape:PowderMolecular weight:152.18 g/mol4-Thiouracil
CAS:4-Thiouracil is a uridine analog and has been shown to inhibit transcriptional regulation by hydrogen bonding with the dna template. 4-Thiouracil is a prodrug that is converted to its active form, thiouracil, which inhibits DNA synthesis and cell proliferation by inhibiting the enzyme topoisomerase II. This results in the formation of abnormal DNA molecules that are not replicated properly. Thiouracil also has photochemical properties due to its ability to absorb light at wavelengths below 400 nm. The photochemical properties of 4-thiouracil have been studied extensively as models for human tissue culture and the study of cancer cells.Formula:C4H4N2OSPurity:Min. 97 Area-%Color and Shape:Slightly Yellow PowderMolecular weight:128.15 g/mol8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,9-dihydro-1H-purine-2,6-dione
CAS:Controlled ProductPlease enquire for more information about 8-[(1E)-2-(3,4-Dimethoxyphenyl)ethenyl]-1,3-diethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C19H22N4O4Purity:Min. 95%Color and Shape:PowderMolecular weight:370.4 g/mol5-Chlorouracil
CAS:5-Chlorouracil is a drug that is used to treat cancer. It has been shown to have biological properties, and its mechanism of action is not yet fully understood. 5-Chlorouracil can be synthesized in the laboratory by reacting sodium hydroxide with 5-chloro-2,4(1H,3H)-pyrimidinedione. In wastewater treatment plants, it reacts with organic matter in the water to form nontoxic products, such as carbon dioxide and urea. The reaction solution contains 5-chlorouracil, which undergoes tautomerization spontaneously or through the addition of base. This reaction is reversible, and both the erythro and threo forms are present in solution at equilibrium. The biological properties of 5-chlorouracil have been investigated using sublethal doses in experimental animals. In one study, 5-chlorouracil was found to inhibit xanthine oxidase activity in rats significantly moreFormula:C4H3ClN2O2Purity:Min. 95%Color and Shape:PowderMolecular weight:146.53 g/mol3'-[2- Cyanoethyl N, N- bis(1- methylethyl) phosphoramidite]-5'- O- [bis(4- methoxyphenyl) phenylmethyl] - 2'- O- methyl- N- [2- [4- (1- methylethyl) phenoxy] acetyl] -guanosine
CAS:Please enquire for more information about 3'-[2- Cyanoethyl N, N- bis(1- methylethyl) phosphoramidite]-5'- O- [bis(4- methoxyphenyl) phenylmethyl] - 2'- O- methyl- N- [2- [4- (1- methylethyl) phenoxy] acetyl] -guanosine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C52H62N7O10PPurity:Min. 95%Molecular weight:976.06 g/mol3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine
CAS:3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine (BDBMU) is a pyrimidine derivative that can be used as an antiviral drug. It inhibits the synthesis of DNA and RNA by inhibiting viral polymerase. BDBMU is a prodrug of uracil, which is converted to the active compound in tissues. The benzoylation reaction produces a fluorine atom at C5, which increases its potency. This drug has been shown to have minimal toxicity in tumor cells and has been used for the treatment of leukemia and other cancers.Formula:C17H17F3N2O5Purity:Min. 95%Molecular weight:386.32 g/mol(S)-HPMPA
CAS:(S)-HPMPA is a nucleotide analogue, which is a chemically synthesized compound designed to mimic nucleotides. It acts as both an antiviral and an antitumor agent, sourced primarily through synthetic chemistry involving the modification of naturally occurring nucleotide structures. The mode of action of (S)-HPMPA involves mimicking natural substrates of various viral polymerases and cellular enzymes, thereby inhibiting viral DNA synthesis and disrupting the replication cycle of DNA viruses. Additionally, it can interfere with certain cellular pathways contributing to its antitumor effects.Formula:C9H14N5O5PPurity:Min. 95%Molecular weight:303.21 g/molIsobutyryl Chloride
CAS:Formula:C4H7ClOPurity:>98.0%(GC)(T)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:106.554-Amino-6-hydroxypyrazolo[3,4-d]pyrimidine
CAS:Formula:C5H5N5OPurity:>93.0%(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystallineMolecular weight:151.135-(Ethylthio)-1H-tetrazole
CAS:Formula:C3H6N4SPurity:98%Color and Shape:SolidMolecular weight:130.17152-Chloro-1,3,2-dioxaphospholane
CAS:Formula:C2H4ClO2PPurity:97%Color and Shape:LiquidMolecular weight:126.47871-Methyl-3-nitro-1-nitrosoguanidine
CAS:Formula:C2H5N5O3Purity:95%Color and Shape:LiquidMolecular weight:147.09282-Chloro-1,3,2-dioxaphospholane-2-oxide
CAS:Formula:C2H4ClO3PPurity:95%Color and Shape:LiquidMolecular weight:142.4781Ref: 4Z-G-2434
Discontinued productSYBR GREEN II
CAS:1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity.
Formula:C28H28IN3OSPurity:98%Color and Shape:SolidMolecular weight:581.51Ref: 4Z-G-2447
Discontinued productN4-Benzoylcytosine
CAS:Building block in the synthesis of nucleoside antiviral agents
Formula:C11H9N3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:215.21 g/molRef: 3D-FB03691
Discontinued productUracil
CAS:Pyrimidine nucleobase; allosteric regulator and coenzyme for reactions
Formula:C4H4N2O2Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:112.09 g/molN4-Acetylcytosine
CAS:N4-Acetylcytosine is an inhibitor of serine proteases, glycosidases and nucleosidases. It has been shown to inhibit the replication of a wide range of viruses including HIV, herpes simplex virus type 1, and adenovirus. N4-Acetylcytosine also inhibits the proliferation of cervical cancer cells.
Formula:C6H7N3O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:153.14 g/molRef: 3D-FA05993
Discontinued product
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