Nucleotides
Nucleotides are organic compounds that serve as the building blocks of nucleic acids, essential for the formation of DNA and RNA. Each nucleotide is composed of a nitrogenous base, a sugar molecule, and one or more phosphate groups. These nucleotides join together to form long chains, creating the genetic material that carries and transmits genetic information in all living organisms. In this section, you will find a wide variety of nucleotides crucial for research in genetics, molecular biology, and biochemistry. They are fundamental for studying genetic processes, synthesizing nucleic acids, and developing diagnostic and therapeutic tools. At CymitQuimica, we offer high-quality nucleotides to support your scientific research and applications, ensuring precision and reliability in your experiments
Subcategories of "Nucleotides"
Found 2638 products of "Nucleotides"
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5-Iodo-2'-O-methyluridine
CAS:5-Iodo-2'-O-methyluridine is a novel antiviral drug that inhibits replication of DNA and RNA viruses. It is chemically synthesized from 2' deoxyuridine monophosphate, which is modified to create the 5-iodo derivative. The modification at the 5th position of the uracil ring prevents the incorporation of methylation into DNA and RNA, which can lead to cancerous growths. This compound has been shown to be an excellent activator for DNA synthesis in vitro. It has also been shown to have anticancer properties in vitro and in vivo.Formula:C10H13IN2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:384.12 g/mol9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine
CAS:9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine (9dFdA) is a potent inhibitor of the enzyme s-adenosylhomocysteine hydrolase, which is involved in the synthesis of adenosine. 9dFdA inhibits the growth of Trichomonas vaginalis and has shown good activity against other pathogens, such as Staphylococcus aureus and Mycobacterium tuberculosis. It also has been shown to have potent inhibitory activity against adenosine deaminase, which prevents an immune response by preventing cells from producing the amino acid adenosine. This compound also inhibits uridine phosphorylase, which is involved in nucleotide biosynthesis.Formula:C10H12FN5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:269.24 g/mol3'-Amino-2',3'-dideoxycytidine
CAS:3'-Amino-2',3'-dideoxycytidine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.Formula:C9H14N4O3Purity:Min. 95%Color and Shape:Off-White PowderMolecular weight:226.23 g/mol2'-Deoxyadenosine-5'-diphosphate sodium salt
CAS:2'-Deoxyadenosine-5'-diphosphate sodium salt is a nucleotide that is involved in the synthesis of DNA. It is a structural analog of adenosine-5'-diphosphate and can be used as an experimental tool to study metabolic disorders. 2'-Deoxyadenosine-5'-diphosphate sodium salt binds to p2y receptors and blocks their activation, which inhibits cellular energy metabolism. This compound is structurally similar to adenosine-5'-triphosphate, but has been shown to inhibit the expansion of cells when heated, unlike adenosine-5'-triphosphate. 2'-Deoxyadenosine-5'-diphosphate sodium salt also inhibits cell proliferation in cancer cells and may have potential as a therapeutic agent for bowel disease.Formula:C10H12N5O9P2·xNaPurity:Min. 95 Area-%Color and Shape:PowderMolecular weight:408.18 g/molN4-Acetyl-2'-O-methylcytidine
CAS:N4-Acetyl-2'-O-methylcytidine is a chemical compound that is an analog of cytidine. It has been shown to have the ability to stabilize RNA molecules at high temperatures and has been used in the study of epigenetics and thermophilic organisms. N4-Acetyl-2'-O-methylcytidine is also known as AEMC. This compound can be used for reversed phase high performance liquid chromatography, which separates compounds based on their size and shape. Furiosus is a strain of bacteria that contains this chemical compound in its genome. Furiosus was found to contain this compound in its DNA by using posttranscriptional modification techniques such as high performance liquid chromatography (HPLC) and proton nuclear magnetic resonance (NMR).
Formula:C12H17N3O6Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:299.29 g/mol3'-Fluoro-3'-deoxyuridine
CAS:3'-Fluoro-3'-deoxyuridine is a nucleoside analog that inhibits DNA synthesis and has been used to treat hepatitis.Formula:C9H11FN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:246.19 g/molAdenosine 3',5'-diphosphate disodium salt
CAS:Adenosine 3',5'-diphosphate disodium salt is a nucleotide that is found in all cells and is involved in the regulation of many physiological processes, including energy metabolism and blood flow. It has inhibitory effects on platelets and calcium ion channels. Adenosine 3',5'-diphosphate disodium salt also inhibits the synthesis of prostaglandins by blocking the conversion of arachidonic acid to prostaglandin H2, which leads to an anti-inflammatory effect. Adenosine 3',5'-diphosphate disodium salt has been shown to be effective in treating primary pulmonary hypertension and bowel disease. The reaction solution can be used for polymerase chain reactions, multivariate logistic regression, or other applications.Formula:C10H15N5O10P2·2NaPurity:Min. 96 Area-%Color and Shape:White Beige PowderMolecular weight:473.18 g/mol2'-Deoxy-2'-fluorocytidine
CAS:2'-Deoxy-2'-fluorocytidine is a nucleoside analog with the potential as an Crimean-Congo hemorrhagic fever virus antiviralFormula:C9H12FN3O4Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:245.21 g/mol5-Methoxyuridine
CAS:5-Methoxyuridine is a nucleoside that is structurally related to uridine. It is an intermediate in the biosynthesis of pyrimidines and is also used as a precursor for other compounds. 5-Methoxyuridine has been shown to inhibit protein synthesis by binding to purine receptors and inhibiting the function of protein kinases. The x-ray crystal structures of 5-methoxyuridine bound to two different p2y receptors have been determined. The analytical chemistry of 5-methoxyuridine is based on UV absorption measurements, which are able to identify hydrogen bonds between the base and the sugar moiety. This drug has been investigated for its potential use in cancer therapy due to its ability to inhibit RNA synthesis, which can lead to cell death by incomplete replication or transcription. 5-Methoxyuridine inhibits messenger RNA (mRNA) production in bacteria by interfering with sequence recognition and binding sites within the ribosome and preventingFormula:C10H14N2O7Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:274.23 g/mol2'-Chloro-2'-deoxyuridine
CAS:2'-Chloro-2'-deoxyuridine is a thymidine analog for research applicationsFormula:C9H11ClN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:262.65 g/mol2-Amino-2'-deoxy-2'-fluoroadenosine
CAS:2-Amino-2'-deoxy-2'-fluoroadenosine is a modified nucleoside. Fluorination modifications can make molecules have increased resistance to enzymatic degradation, which has useful applications in drug development. The extra amino group could also enhance binding properties or alter biological activity.Formula:C10H13FN6O3Purity:Min. 95%Color and Shape:PowderMolecular weight:284.25 g/mol3-N-Boc-5'-O-DMT-3'-O-nosylthymidine
CAS:3-N-Boc-5'-O-DMT-3'-O-nosylthymidine is an anticancer nucleoside that is used as a building block for the synthesis of other anticancer compounds. It can be synthesized by the reaction between 3,4,5′-trimethoxybenzoyl chloride and thymidine in the presence of DMAP and DIPEA. This compound has shown antiviral and anti-inflammatory activities. 3-N-Boc-5'-O-DMT-3'-O-nosylthymidine can also be used as a precursor to synthesize novel nucleosides with different properties. This product is soluble in water, ethanol, acetone, chloroform, benzene, ether or methanol.
Formula:C42H43N3O13SPurity:(¹H-Nmr) Min. 95 Area-%Color and Shape:PowderMolecular weight:829.87 g/mol2'-O-Allylcytidine
CAS:2'-O-Allylcytidine is a synthetic nucleotide that contains an allylated amino function. It is synthesized by the regiospecific allylation of uridine and guanosine. 2'-O-Allylcytidine has been used in research studies for the synthesis of oligonucleotides with specific sequences and for high-yield production of synthons.Formula:C12H17N3O5Purity:Min. 95%Color and Shape:PowderMolecular weight:283.28 g/mol2'-Amino-2'-deoxyguanosine
CAS:2'-Amino-2'-deoxyguanosine is a modified nucleoside, based on guanosine. The 2'-hydroxyl has been replaced by an amino group, which can form different hydrogen bonds compared to a hydroxyl or just a hydrogen, altering the way the sugar interacts in a DNA or RNA strand.Formula:C10H14N6O4Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:282.26 g/molTenofovir
CAS:Tenofovir is an acyclic nucleoside phosphonate that exhibits anti-viral properties through its inhibition of reverse transcriptases. In particular, Tenofovir is a potent inhibitor of Human Immunodeficiency Virus (HIV) and chronic Hepatitis B Virus (HBV) reverse transcriptases, thus preventing the replication of genetic viral material. This property is beneficial in virus research areas and developing antiviral treatments. Once inside the body tenofovir is metabolized into its active form, tenofovir diphosphate, by the lysosomal protease cathepsin A, nucleotide kinases and adenylate kinases. An oral prodrug, used in the treatment of HIV, is tenofovir alafenamide (TAF) hemifumerate and this has improved stability, greater antiviral activity and reduces the risk of side effects such as loss of kidney function. Furthermore, TAF is easily metabolized into tenofovir in the lymphocytes allowing increased drug accumulation in HIV cells.Formula:C9H14N5O4PPurity:Min. 95%Color and Shape:White Clear LiquidMolecular weight:287.21 g/mol7-Deaza-2'-deoxyinosine
CAS:7-Deaza-2'-deoxyinosine is a purine nucleoside analog that has been shown to be a hydrogen bond donor and formamide acceptor. This drug destabilizes duplex DNA by interfering with the formation of the hydrogen bonds between the bases, which may result in strand breakage. 7-Deaza-2'-deoxyinosine has also been shown to inhibit RNA polymerase activity, thereby inhibiting protein synthesis. It has been used as a tool for studying enzyme mechanisms and in solid phase synthesis.
Formula:C11H13N3O4Purity:Min. 95%Color and Shape:PowderMolecular weight:251.24 g/mol5'-Deoxy-5'-iodoadenosine
CAS:5'-Deoxy-5'-iodoadenosine is a nucleoside analog that inhibits the activity of the adenosine receptor. This drug binds to adenosine receptors, which are found on the surface of cells. The binding results in an inhibitory effect on viral replication and cell proliferation. 5'-Deoxy-5'-iodoadenosine has been shown to be effective against hepatitis B virus, hepatitis C virus, and human T-cell leukemia virus type 1 (HTLV-1). It is also active against animal models of human diseases such as l1210 murine leukemia and t-cell leukemia. 5'-Deoxy-5'-iodoadenosine has been shown to inhibit the growth of hl-60 cells in cell culture by blocking the synthesis of adenylate cyclase and protein kinase A.Formula:C10H12IN5O3Purity:Min. 95%Color and Shape:PowderMolecular weight:377.14 g/mol5-Bromouridine
CAS:5-Bromouridine is an energy-related metabolite that is a precursor of uridine. It is a nucleotide base that is incorporated into DNA during DNA replication. 5-Bromouridine has been shown to have radiation resistance and high resistance to viral life. It also binds to the nuclear DNA in cells, where it can act as a transcriptional regulator. 5-Bromouridine is used in the treatment of malignant brain tumors, where it can inhibit tumor growth by binding to the dna of cancer cells and preventing the synthesis of proteins required for cell division. 5-Bromouridine binds with high affinity to basic fibroblast, which may be related to its effects on cancer cells.Formula:C9H11BrN2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:323.1 g/mol8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt
CAS:Activator of cGMP-dependent protein kinasesFormula:C10H10BrN5NaO7PPurity:Min. 95%Color and Shape:PowderMolecular weight:446.08 g/molN4-Benzoyl-3'-deoxycytidine
CAS:N4-Benzoyl-3'-deoxycytidine is a novel antiviral agent that has shown activity against DNA and RNA viruses. It is an activator of DNA polymerase, which is essential for replication of viral nucleic acids. The compound is a modified nucleoside with a benzoyl group at the 4' position of the ribose moiety. It also has phosphoramidite, monophosphate, and diphosphate analogues. N4-Benzoyl-3'-deoxycytidine binds to the enzyme DNA polymerase, thereby inhibiting its ability to synthesize deoxyribonucleotides from ribonucleotides. This results in inhibition of viral DNA synthesis and subsequent inhibition of viral replication.Formula:C16H17N3O5Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:331.32 g/mol
