
Nucleotides
Subcategories of "Nucleotides"
Found 2637 products of "Nucleotides"
2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine
CAS:2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl-guanosine is a synthetic nucleoside that has been modified with a tert-butyldimethylsilyl group. This modification is used to improve the efficiency of coupling reactions between nucleosides and phosphoramidites in oligonucleotide synthesis. The 2'-O-(tert-Butyldimethylsilyl)-5'-O-DMT-N2-isobutyryl guanosine is also used as a chromophore in spectroscopy experiments and as a ligand in metal coordination chemistry.Formula:C41H51N5O8SiPurity:Min. 98 Area-%Color and Shape:Off-White PowderMolecular weight:769.96 g/mol1-(β-D-Arabinofuranosyl)thymine
CAS:1-(β-D-Arabinofuranosyl)thymine is a nucleoside analog. It has a similar structure to thymidine. It has possible applications in research into the specificity and kinetics of thymidine kinases and has demonstrated antiviral activity against some viruses.Formula:C10H14N2O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:258.23 g/molβ-Nicotinamide Adenine Dinucleotide Disodium Salt, reduced form [for Biochemical Research]
CAS:Formula:C21H27N7Na2O14P2Color and Shape:White to Orange to Green powder to crystalMolecular weight:709.41Adenosine 5'-diphosphate disodium salt
CAS:Adenosine 5'-diphosphate disodium salt is a sodium salt of adenosine 5'-diphosphate. It is found in the extract of plants such as salvianolic acid and rhizoma gastrodiae, as well as in dinucleotide phosphate. This product has been shown to have cardioprotective effects against ischemia reperfusion injury in animal models. It also has congestive heart failure activity, which may be due to its ability to relax vascular smooth muscle and increase the diameter of lymphatic vessels. Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
Formula:C10H13N5Na2O10P2Purity:Min. 95 Area-%Color and Shape:White PowderMolecular weight:471.16 g/molAzathioprine
CAS:Formula:C9H7N7O2SPurity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:277.26Cytidine 5'-diphosphocholine
CAS:Cytidine 5'-diphosphocholine is a nucleotide that is a precursor of uridine 5'-triphosphate and cytidine 5'-monophosphate, which are important for DNA synthesis. Cytidine 5'-diphosphocholine is used in the preparation of samples for experiments. This compound has been shown to induce neuronal death in an experimental model. It has also been shown to inhibit polymerase chain reactions and affect the activity of enzymes such as alpha-7 nicotinic acetylcholine receptors and glutamate decarboxylase. Cytidine 5'-diphosphocholine has been found to have no effect on basic fibroblast cells, but it does have physiological effects on human erythrocytes.Formula:C14H26N4O11P2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:488.32 g/mol5-Aza-7-deazaguanosine
CAS:5-Aza-7-deazaguanosine is a nucleoside analogue that has antiviral activity against herpes simplex virus, influenza, and other DNA viruses. 5-Aza-7-deazaguanosine is an analog of guanosine with the addition of a 7-deaza group on the nitrogen atom. This drug inhibits viral replication by inhibiting the polymerase function of the viral NS5B protein, which is essential for DNA synthesis. The structure activity relationship studies have shown that this compound has anti-hepatitis B virus activity, but not against hepatitis C virus. 5-Aza-7-deazaguanosine has been shown to be effective in animal models as well as in humans without any significant toxicity issues.Formula:C10H13N5O5Purity:Min. 95%Color and Shape:PowderMolecular weight:283.24 g/mol5-Fluorouridine-5'-triphosphate sodium salt
CAS:5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.Formula:C9H14N2O15P3FPurity:Min. 95%Molecular weight:502.13 g/mol5'-O-DMT-N2-isobutyrylguanosine
CAS:5'-O-DMT-N2-isobutyrylguanosine is a novel phosphoramidite monophosphate, which has been modified with an isobutyryl group. This compound was synthesized in order to be used as a nucleoside analogue and antimetabolite for the treatment of cancer. It also has antiviral properties and inhibits the replication of DNA by inhibiting transcription. 5'-O-DMT-N2-isobutyrylguanosine is an anticancer agent that can be used to treat tumors that are resistant to other chemotherapy drugs. It also inhibits the growth of cells by preventing the synthesis of proteins needed for cell division.
Formula:C35H37N5O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:655.7 g/molGuanosine 5'-monophosphate disodium salt
CAS:Guanosine 5'-monophosphate disodium salt (GMPDS) is an antiviral agent that inhibits the synthesis of viral nucleic acids by competitive inhibition of the enzyme ribonucleotide reductase. GMPDS has been shown to inhibit the replication of a number of RNA viruses, including influenza A and B, herpes simplex virus type 1, and human immunodeficiency virus type 1. This drug also has been shown to decrease cyclic adenosine monophosphate (cAMP) levels in cells by inhibiting phosphodiesterase activity. GMPDS is used for treatment of infectious diseases such as influenza A, herpes, and HIV-1.Formula:C10H12N5Na2O8PPurity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:407.18 g/molCytidine-5-carboxylic acid sodium
CAS:Cytidine-5-carboxylic acid sodium salt is a nucleoside that is used as an activator for the synthesis of phosphoramidites. It is also used in anticancer and antiviral research as a component of DNA. Cytidine-5-carboxylic acid sodium salt is available in high purity, with a monophosphate form and diphosphate forms available.Formula:C10H13N3O7•NaPurity:Min. 95%Color and Shape:PowderMolecular weight:310.21 g/mol8-Methyladenosine
CAS:8-Methyladenosine is an acid conjugate that can be found in the urine of healthy people. It is a protonated molecule that binds to a p2 subtype of the G protein-coupled receptor, which is activated by adenosine and 8-methyladenosine. This drug has been used in clinical trials for the treatment of herpes simplex virus and cervical cancer. The intramolecular hydrogen bond between the methyl group and the adenosine ring is responsible for its high binding affinity for this receptor. The glycosidic bond is formed when an 8-methyladenosine molecule attaches to a receptor on a cell surface, forming an intramolecular hydrogen bond with the receptor's amino acid side chain. This bond is broken when a protonated molecule of 8-methyladenosine enters the cell and interacts with the receptor, resulting in activation of this receptor.
Formula:C11H15N5O4Purity:Min. 95%Color and Shape:White PowderMolecular weight:281.27 g/mol2'-Deoxy-a-guanosine
CAS:2'-Deoxy-a-guanosine is a nucleoside that is modified by the substitution of its ribose sugar with deoxyribose. It is used in anticancer and antiviral research. This chemical has been shown to inhibit DNA synthesis and RNA polymerase activity. 2'-Deoxy-a-guanosine has also been shown to have an anti-inflammatory effect, which may be due to its inhibition of prostaglandin synthesis.Formula:C10H13N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:267.25 g/mol4-(b-D-Ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one
CAS:Ribonucleosides, Deoxyribonucleosides and Activator are a group of synthetic compounds that are used in the synthesis of DNA. Ribonucleosides and Deoxyribonucleosides are nucleotides that contain ribose or deoxyribose as the sugar moiety. Activator is an activator for DNA polymerase, which catalyses the formation of a phosphodiester bond between two adjacent 3'-5' phosphate groups on a single strand of DNA. Ribonuclesides, Deoxyribonucleosides and Activator are used in recombinant DNA technology to synthesize DNA molecules containing modified bases. The CAS number for Ribonuclesides, Deoxyribonucleosides and Activator is 59892-40-9.
Formula:C10H12N4O5Purity:Min. 95%Molecular weight:268.23 g/molGuanosine 3',5'-bisdiphosphate lithium salt - 100mM aqueous solution
CAS:Regulates gene transcription; inhibits the synthesis of tRNA and rRNAFormula:C10H17N5O17P4·xLiPurity:Min. 85 Area-%Color and Shape:Colorless PowderMolecular weight:602.16 g/moldNTP bundle, 4 x 100mM aqueous solution
CAS:Each dNTP supplied in a separate vialPurity:Min. 99 Area-%Color and Shape:Clear LiquidUridine 3'-monophosphate disodium salt
CAS:Uridine 3'-monophosphate disodium salt is a nucleotide that is part of the pyrimidine family. It is synthesized from uridine and phosphoric acid in a reaction that requires hydrogen bonding and the presence of an enzyme. Uridine 3'-monophosphate disodium salt has been shown to inhibit the production of eosinophil cationic protein, which may be due to its ability to denature proteins. This drug also has an effect on the synthesis of proteins by inhibiting enzymes such as acetylcholinesterase and catalase. The synthesis of glycosidic bonds is also inhibited, which may lead to an increase in body mass index (BMI).Formula:C9H11N2Na2O9PPurity:Min. 95%Color and Shape:White PowderMolecular weight:368.15 g/mol2,4-Diamino-6-hydroxypyridine sulphate
CAS:2,4-Diamino-6-hydroxypyridine sulphate is a nucleoside for use in research applicationsFormula:C4H6N4O•(H2SO4)xPurity:Min. 95%Color and Shape:PowderMolecular weight:224.2 g/mol2'-Deoxy-L-uridine
CAS:2'-Deoxy-L-uridine is a nucleoside that is found in the human body. It phosphorylates l-thymidine, which is a natural substrate, and this reaction prevents the formation of diphosphate from d-ribose 5'-monophosphate. 2'-Deoxy-L-uridine is an exogenous substance that inhibits cell growth by affecting protein synthesis and DNA replication. 2'-Deoxy-L-uridine has been shown to be more efficient than wild type uridine in inhibiting cell growth in vitro at concentrations of 1 mM or greater. The enantiomers of 2'-deoxy-L-uridine affect cell growth differently, with the (R)-enantiomer being more potent than the (S)-enantiomer.
Formula:C9H12N2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:228.2 g/mol2'-O-Methylinosine
CAS:2'-O-Methylinosine is a nucleoside that is structurally related to inosine. It has been shown to induce apoptotic cell death in HIV-infected cells by inhibiting the synthesis of rRNA and by inhibiting the activity of the transcriptase enzyme. 2'-O-Methylinosine has also been shown to inhibit the replication of RNA viruses, such as herpes simplex virus and cytomegalovirus, and it can be used as an experimental model for studying apoptosis. 2'-O-Methylinosine can be synthesized from inosine using a chromatographic method that utilizes hydroxylamine. The chemical structure of this nucleoside is amphipathic, which allows it to bind both DNA and RNA strands.Formula:C11H14N4O5Purity:Min. 99 Area-%Color and Shape:White PowderMolecular weight:282.25 g/mol

