Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
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3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester
3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester is a novel nucleoside analogue with anticancer and antiviral properties. It is an activator of ribonucleosides and deoxyribonucleosides, which are used for the synthesis of DNA and RNA respectively. 3'-Azido-3'-deoxythymidine 2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester can be used to synthesize phosphoramidites and modified nucleosides. The compound has been shown to have antitumor activity in vitro against human leukemia cells.Formula:C23H29N5O13Purity:Min. 95%Molecular weight:583.5 g/mol2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
2'-Azido-2'-deoxyguanosine-5'-triphosphate lithium salt is a chemically modified nucleotide analog in which the 2'-hydroxyl group of guanosine is replaced by an azido group, and the molecule is phosphorylated at the 5' position with a triphosphate moiety, forming a lithium salt for stability and solubility. This molecule has potential in research applicationsFormula:C10H15N8O13P3Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:548.19 g/mol2-Hydrazino-4-(trifluoromethyl)pyrimidine
CAS:2-Hydrazino-4-(trifluoromethyl)pyrimidine is a cancer drug that is used in the treatment of various types of cancers. It is a chelate ring with a coordination geometry group P2, which has been shown to have low detection in urine and blood samples. 2-Hydrazino-4-(trifluoromethyl)pyrimidine binds copper ions, forming a copper complex, which causes the release of chloride ions. This process leads to an increased level of hydrogen peroxide and hydroxyl radicals that induce cancer cell death by inhibiting DNA synthesis and protein synthesis. 2-Hydrazino-4-(trifluoromethyl)pyrimidine also inhibits the production of certain enzymes (such as cyclooxygenase), which are involved in the production of prostaglandins that promote tumor growth.Purity:Min. 95%m7G(5')ppp(5')Guanosine
CAS:A cap analog that can incorporated into mRNAFormula:C21H29N10O18P3Purity:Min. 95%Molecular weight:802.43 g/mol2'-Deoxy-5- chloro -2', 2'- difluorocytidine
CAS:2'-Deoxy-5-chloro-2',2'-difluorocytidine is a monophosphate nucleoside with antiviral and anticancer activity. It is an activator of DNA polymerase, which is important for DNA synthesis. 2'-Deoxy-5-chloro-2',2'-difluorocytidine has been shown to be synthesized in high purity and with novel modifications that are not found in natural nucleosides. This compound may have the potential to be used as a therapeutic agent for cancer treatment or as an antiviral drug.Purity:Min. 95%N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt
N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt is a modified nucleotide that has been shown to have anticancer and antiviral activity. N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt inhibits the synthesis of viral DNA and also inhibits the production of DNA in tumor cells. This compound is a phosphoramidite, which is an activated ester of a nucleoside with a phosphate group. The active form of this drug is adenosine triphosphate (ATP), which acts as an activator for DNA synthesis, leading to the production of deoxyribonucleosides and monophosphate, which are necessary for DNA replication.Purity:Min. 95%N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS:N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel nucleoside analogue that was synthesized from a cytidine analogue. This compound has antiproliferative activity against cancer cells in vitro and in vivo. The mechanism of action is not yet known, but it is thought to be due to the inhibition of DNA synthesis and/or the induction of apoptosis. N4-Acetyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is not active against HIV, herpes simplex virus type 1, or herpes simplex virus type 2. It also has no effect on the replication of the influenza A virus and cannot inhibit the replication of poliovirus type 1.
Formula:C38H47N3O8SiPurity:Min. 95%Molecular weight:701.88 g/molCytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3
Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 is a novel nucleotide analogue that is synthesized from the corresponding phosphoramidite. It has antiviral activity and can be used as an analog of cytosine arabinoside for the treatment of herpes zoster. Cytarabine-5-b,Y-(1-hydroxyethylidene) triphosphate-d3 has been shown to inhibit viral replication by interacting with DNA and RNA synthesis. This drug also inhibits DNA polymerase activity in vitro and blocks viral transcription. Cytarabine can be used in combination with other antiviral drugs such as acyclovir or ganciclovir.Purity:Min. 95%5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine
5'-O-DMT-N2-isobutyryl-9-(b-D-arabinofuranosyl)guanine is a nucleoside analog drug that has antiviral and anticancer properties. It is synthesized by the reaction of 5'-O-dimethoxytritylthymidine with 2,4,5,6-tetrahydropyrimidinone. This compound has been shown to be active in vitro against several viruses including herpes simplex virus type 1 (HSV1) and human immunodeficiency virus type 1 (HIV1). The antiviral activity of 5'-O-DMT-N2-isobutyrylguanine is due to inhibition of viral DNA polymerase and/or virion assembly. It also inhibits tumor cell growth in vitro.Formula:C35H37N5O8Purity:Min. 95%Molecular weight:655.71 g/mol2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt
2',3'-Didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt is a nucleoside analog that inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. It has been shown to be effective against cancer cells in vitro and in vivo. Although it is not active against mycobacterium and other acid-fast bacteria, 2',3'-didehydro-3'-deoxy-thymidine-5'-triphosphate, lithium salt has shown promising anticancer properties and may be useful for the treatment of leukemia, lymphoma, and breast cancer.Purity:Min. 95%8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate
CAS:8-(2-Aminoethyl)aminoadenosine 3',5'-cyclic monophosphate (8-AEACMP) is a structural analog of the purine nucleotide adenosine. It has been shown to be an effective inhibitor of HIV replication in vitro and in vivo. 8-AEACMP blocks HIV transcription by binding to the cellular target, the enzyme ribonucleotide reductase. This binding prevents the formation of an enzyme-substrate complex that is required for DNA synthesis. 8-AEACMP binds to two sites on this enzyme: one site is at a catalytic site that is not involved in substrate binding, and the other site is at a regulatory site. The inhibitory effect of 8-AEACMP on HIV transcription results from its ability to bind at both sites simultaneously.Formula:C12H18N7O6PPurity:Min. 95%Molecular weight:387.29 g/mol2',3'-Dideoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:2',3'-Dideoxyguanosine-5'-triphosphate lithium salt (ddGTP) is a nucleotide analogue that inhibits the activity of DNA polymerase, RNA polymerase, and other enzymes. It has been shown to be an effective inhibitor of primary breast cancer cells in vitro. ddGTP is also a fluorescent compound with a light emission maximum at about 520 nm. The fluorescence intensity increases with increasing concentrations of ddGTP. This product is supplied as a 100mM aqueous solution containing ddGTP.Formula:C10H16N5O12P3Purity:Min. 95%Molecular weight:491.18 g/mol[(2R,3S,4R,5R)-5-(4-Benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4-fluoro-4-methyloxolan-2-yl]methyl benzoate
CAS:[(2R,3S,4R,5R)-5-(4-Benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4-fluoro-4-methyloxolan-2-yl]methyl benzoate is a novel anticancer drug that selectively inhibits the proliferation of cancer cells. It binds to the DNA and RNA in tumor cells to inhibit nucleotide synthesis and leads to cell death. This product has high purity and is modified for use.Formula:C31H26FN3O7Purity:Min. 95%Molecular weight:571.6 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-uridine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-uridine is a novel nucleoside with antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine is activated by ribonucleoside kinase, which phosphorylates the 4'-C position on the sugar moiety to form the monophosphate. This drug has been shown to inhibit proliferation of human lymphoid leukemia cells in culture and to inhibit replication of HIV in cell culture. 4'-C-Azido-2'-deoxy-2'-fluoro-uridine also inhibits herpes simplex virus type 1 (HSV1) replication in vitro.
Formula:C9H10FN5O5Purity:Min. 95%Molecular weight:287.2 g/mol8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine
CAS:8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is an anti-cancer, antiviral, and anticancer agent. It has shown anticancer activity in a number of animal models. This drug also inhibits the replication of DNA by inhibiting the synthesis of DNA precursors. 8-Allyloxy-N2-(dimethylaminomethylidene)-2-deoxyguanosine is synthesized from 2,6-diaminohexane and 1,3,5-triazine by reaction with formaldehyde and allyl bromide in the presence of potassium hydroxide. The product is purified by chromatography on silica gel using a mixture of chloroform/methanol (1:1) as eluent to yield a colorless liquid. The chemical structure is characterized by IR spectroscopy and mass spectrometry.Formula:C16H22N6O5Purity:Min. 95%Molecular weight:378.38 g/mol1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine
CAS:1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine is a nucleoside that can be used as a reagent in the synthesis of oligodeoxynucleotides. It has been shown to bind to DNA, and it is phosphoramidite monomer for solid phase synthesis of oligodeoxynucleotides. It is also a nonamer, octamer, and dinucleoside. 1-(2'-Deoxy-5'-O-DMT-b-D-lyxofuranosyl)thymine binds to the receptor protein and has been shown to have efficiencies as high as 45%.Formula:C31H32N2O7Purity:Min. 95%Molecular weight:544.6 g/molAdenosine 5'-triphosphate potassium salt
CAS:Adenosine 5'-triphosphate potassium salt is a membrane potential-sensitive fluorescent probe. It has been used to measure the intensity of light exposure and the depolarising effects of activation in sarcoplasmic reticulum vesicles. Adenosine 5'-triphosphate potassium salt has also been used to measure the activity of cyclic nucleotide phosphodiesterases, which are enzymes that regulate the breakdown of cAMP and cGMP. The fluorescence of adenosine 5'-triphosphate potassium salt increases with increased concentrations of cyclic nucleotide phosphodiesterase, indicating that it is an effective indicator for measuring these types of enzymes in biological assays.
Formula:C10H14K2N5O13P3Purity:Min. 95%Molecular weight:583.36 g/molUridine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Mixture of Rp and Sp isomers.Formula:C9H15N2O14P3SPurity:Min. 95%Molecular weight:500.21 g/mol2'-Deoxyguanosine-5'-diphosphate disodium salt
CAS:2'-Deoxyguanosine-5'-diphosphate disodium salt is a marine metabolite that is used as a chemotactic agent for bacteria. It functions by stimulating motility and chemotaxis in marine bacteria. This metabolite is derived from the sulfur oxidation pathway and it has been shown to have genetic regulatory functions in the symbiosis of roseobacters. 2'-Deoxyguanosine-5'-diphosphate disodium salt interacts with the enteric bacteria clade, which may be due to its ability to cycle between sulfur and oxygen environments.Formula:C10H13N5O10P2·2NaPurity:Min. 95%Color and Shape:White PowderMolecular weight:471.16 g/mol5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt
5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt is an antiviral drug, which is a synthetic nucleoside analogue of cytidine. It inhibits the synthesis of viral DNA by competing with deoxycytidine triphosphate for incorporation into nascent DNA chains. This antiviral agent has been shown to be effective against HSV-1 and HIV-1 in vitro.Purity:Min. 95%2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole
CAS:2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside with anticancer activity. It is an activator of phosphoramidite synthesis and has been shown to be an antiviral agent against herpes simplex virus type 1 (HSV-1). 2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside that can be used for the synthesis of DNA or RNA. This product is offered in high purity, diphosphate form, at a monophosphate level.Formula:C34H32N2O7Purity:Min. 95%Molecular weight:580.63 g/molN2-Carbamoylthreonyl-2'-deoxyguanosine
N2-Carbamoylthreonyl-2'-deoxyguanosine is a phosphoramidite monophosphate that is used in the synthesis of DNA. It has antiviral and anticancer properties. N2-Carbamoylthreonyl-2'-deoxyguanosine is synthesized by modifying the nucleoside thymidine, which contains a 2'-deoxyribose sugar and an amino sugar, with carbamate linkages at the 2' position. This modification stabilizes the sugar moiety, preventing it from undergoing hydrolysis to form ribose and deoxyribose. The stability of the modified nucleoside allows for increased solubility in aqueous solution and increased resistance to degradation by nucleases. N2-Carbamoylthreonyl-2'-deoxyguanosine also has high purity and quality as well as novel modifications not found in other DNA building blocksPurity:Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS:N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel modified nucleoside that is an activator of ribonucleosides. It has antiviral and anticancer activities, in addition to its potential as a DNA polymerase inhibitor. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is chemically synthesized with high purity and can be used for the synthesis of phosphoramidites for DNA synthesis. This compound also has the CAS number 12105885 3 and can be found in monophosphate form.Formula:C38H47N3O8SiPurity:Min. 95%Color and Shape:PowderMolecular weight:701.88 g/mol2'-Deoxy-5-fluorocytidine 5'-monophosphate
CAS:2'-Deoxy-5-fluorocytidine 5'-monophosphate is a nucleotide that is synthesized by the enzyme cytidine deaminase. It is used as a diagnostic agent in the detection of infectious diseases such as HIV, Mycobacterium tuberculosis, and cytomegalovirus (CMV). 2'-Deoxy-5-fluorocytidine 5'-monophosphate inhibits DNA synthesis by blocking the incorporation of deoxycytidylate into DNA. The compound is also an inhibitor of collagen synthesis in tissues and cells. Hydrogen bonds between this compound and its target enzymes are thought to be important for its inhibitory effects.
Formula:C9H13FN3O7PPurity:Min. 95%Molecular weight:325.19 g/mol4'-C-Azido-3'-deoxy-3'-fluorocytidine
CAS:4'-C-Azido-3'-deoxy-3'-fluorocytidine is an antiviral, anticancer, and nucleoside phosphoramidite. It is a novel modified nucleoside that has antiviral, anticancer, and DNA modifying properties. 4'-C-Azido-3'-deoxy-3'-fluorocytidine has been shown to be an activator of the polymerase chain reaction (PCR). This product has high purity with no detectable impurities. The CAS number for this compound is 1145869-46-0. This product is available in bulk quantities.
Formula:C9H11FN6O4Purity:Min. 95%Molecular weight:286.22 g/mol2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt - 100mM aqueous solution
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is a novel, synthetic nucleoside. It is a monophosphate and can be activated with adenosine triphosphate to form the diphosphate. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is also an antiviral agent that inhibits viral RNA synthesis. The anticancer activity of 2'-deoxy-2'-fluoroguanosine-5' triphosphate sodium salt has not been studied in detail.Formula:C10H15FN5O13P3·NaPurity:Min. 95%Molecular weight:548.16 g/mol2',3'-Anhydrothymidine
CAS:2',3'-Anhydrothymidine is a nucleoside analogue that has been shown to inhibit HIV-1 transcriptase and polymerase by binding to the enzyme's active site. It also inhibits DNA synthesis in human cells and inhibits the growth of E. coli. 2',3'-Anhydrothymidine is a prodrug that can be taken up by cells, where it is converted into an epoxide, which then binds to the enzyme's active site. This prevents the enzyme from catalyzing reactions and terminating DNA synthesis at the correct point during transcription. 2',3'-Anhydrothymidine may also have immunodeficiency-related benefits due to its ability to bind more tightly to dsDNA than natural nucleotides, causing termination of RNA synthesis at the wrong point.Formula:C10H12N2O5Purity:Min. 95%Molecular weight:240.21 g/molN-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine
CAS:N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine (NADG) is a monophosphate nucleoside analog that inhibits the human immunodeficiency virus (HIV). NADG inhibits HIV by binding to the viral enzyme reverse transcriptase and inhibiting its activity. NADG also has anticancer activity through inhibition of DNA synthesis and protein synthesis. This compound is a novel nucleoside analog that has not been previously described in the literature.Formula:C21H22N10O4Purity:Min. 95%Molecular weight:478.46 g/mol1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil
CAS:1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil (1dTfu) is an anticancer drug that belongs to the group of anti-metabolites. It is used in the treatment of colon cancer, head and neck cancer, urinary bladder cancer, and prostate cancer. 1dTfu inhibits the production of tyrosinase and other growth factors, which may be due to its ability to bind to a receptor called factor receptor on the surface of cells. This binding inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. 1dTfu also has been shown to inhibit collagen synthesis via an extracellular mechanism.Formula:C9H11FN2O5Purity:Min. 95%Molecular weight:246.19 g/mol2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine
2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that can be activated with phosphoramidite and used to synthesize a variety of modified nucleosides. It has been shown to have anticancer and antiviral activities, as well as the ability to inhibit the replication of RNA viruses. 2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine is also useful in the synthesis of monophosphate nucleotides, which are important for DNA synthesis. This product is available in high purity and quality and is CAS No.Purity:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite is a novel, high quality nucleoside that is synthesized by the reaction of 5'-O-DMT-2'-deoxyguanosine with isobutyryl chloride. It has antiviral and anticancer properties and has been shown to be an activator of RNA polymerase. CAS number: 89879-16-1Formula:C44H54N7O8PPurity:Min. 95%Molecular weight:839.94 g/mol4-Amino-6-chloropyrimidine-5-carbaldehyde
CAS:4-Amino-6-chloropyrimidine-5-carbaldehyde is a reactive molecule that is used in the synthesis of macrocyclic aldehydes. It is prepared by the oxidation of anilines with oxalyl chloride in the presence of hydrochloric acid and amines. 4-Amino-6-chloropyrimidine-5-carbaldehyde reacts with hydrazine to form diamines, which are used as building blocks for pharmaceuticals. This molecule has been shown to have anticancer properties, by inhibiting DNA replication and cell growth through its ability to inhibit protein synthesis.Formula:C5H4ClN3OPurity:Min. 95%Molecular weight:157.56 g/mol5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile
CAS:5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile is a novel, modified ribonucleoside monophosphate that has antiviral, anticancer, and antiretroviral properties. It was originally synthesized as an activator of the DNA polymerase and is capable of stimulating the synthesis of RNA from DNA templates. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile is also a phosphoramidite nucleotide analog that can be incorporated into DNA during DNA synthesis.Formula:C11H11N3O4Purity:Min. 95%Molecular weight:249.22 g/molS-(2-Hydroxy-5-nitrobenzoyl)-6-thioinosine
CAS:S-(2-Hydroxy-5-nitrobenzoyl)-6-thioinosine is a population of endogenous inotropic agents that are transported by the uptake system. It interacts with benzodiazepine receptor and has been shown to act as an agonist. The uptake system is responsible for the uptake of S-(2-hydroxy-5-nitrobenzoyl)-6-thioinosine, which then binds to the benzodiazepine receptor. This binding causes an increase in cAMP levels and subsequent relaxation of smooth muscle cells. S-(2-hydroxynitrobenzoyl)-6-thioinosine has been shown to be a transport inhibitor, which affects the uptake of other drugs such as benzodiazepines and antiepileptics. It also modulates responsiveness through interaction with the transport system.Formula:C17H17N5O7SPurity:Min. 95%Molecular weight:435.41 g/mol2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine
CAS:2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine is a novel, activator ribonucleoside phosphoramidite and monophosphate nucleoside. It is synthesized from 2,4,5,6,-tetraiodo-1H-[1]pyrrole and 6-chloropurine ribofuranose. The chemical name is 1-[2'-(deoxyribofuranosyl) (3', 3'', 5', 5'', 5'')-2'-(2,4,5,6 tetraiodophenyl)] -2-(3'-fluorobenzoyl) -4-(3'-triazolecarboxamide) -1H-[1]pyrrole 4,5 dione. CAS No. 1612192-05-8.Purity:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-(2-Isopentenyl)adenosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-(2-Isopentenyl)adenosine 3'-CE phosphoramidite is an antiviral nucleoside, which is synthesized by the reaction of 2'-deoxyribonucleosides with the activator. This product is a novel chemical compound that has antiviral and anticancer activity. It can be used as a precursor for other nucleosides.Purity:Min. 95%Guanosine 5'-triphosphate trisodium hydrate
CAS:Guanosine 5'-triphosphate trisodium hydrate is a novel antiviral agent that was discovered in the course of a research program to find new antiviral agents. It is an activator of guanylyl cyclase and it has been shown to have high quality and high purity. Guanosine 5'-triphosphate trisodium hydrate binds to ribonucleosides and deoxyribonucleosides, preventing their incorporation into viral DNA or RNA. This compound also has anticancer activity.Formula:C10H18N5NaO15P3Purity:Min. 95%Molecular weight:564.19 g/mol1-[(5E)-5,6-Dideoxy-6-(diethoxy phosphinyl)-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil
CAS:1-[(5E)-5,6-Dideoxy-6-(diethoxy phosphinyl)-2-O-methyl-beta-D-ribo-hex-5-enofuranosyl]uracil is a novel monophosphate that was synthesized by modifying a known anticancer nucleoside. It is an activator of the antiviral ribonucleotide reductase and deoxyribonucleotide reductase. 1-[(5E)-5,6-Dideoxy-6-(diethoxy phosphinyl)-2-O-methyl-beta-D-ribohexanofuranosyl]uracil has been shown to inhibit the proliferation of cancer cells in vitro and in vivo. It also inhibits tumor growth without affecting normal tissue.Purity:Min. 95%2-Chloro-6-(2'-deoxy-b-D-ribofuranosyl)-3,5-diaminopyrazine
CAS:2-Chloro-6-(2'-deoxy-b-D-ribofuranosyl)-3,5-diaminopyrazine is a modified nucleoside that can be used to synthesize DNA and RNA. It is an activator that activates the phosphoramidite coupling reaction of the synthesis of DNA. 2-Chloro-6-(2'-deoxy-b-D-ribofuranosyl)-3,5-diaminopyrazine has been shown to have anticancer and antiviral activities in vitro, but no in vivo data are currently available. It also has high purity and high quality.Formula:C9H13ClN4O3Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:260.68 g/mol2',3'-Anhydroinosine
CAS:2',3'-Anhydroinosine is an analog of the purine nucleoside inosine, which has been synthesized by catalytic dehalogenation of 2-fluoro-adenosine. The synthesis of this compound is based on a chemical reaction between 2-fluoro-adenosine and sodium hydroxide. This reaction produces 2',3'-anhydroinosine as a byproduct. 2',3'-Anhydroinosine inhibits the enzyme purine nucleoside phosphorylase, which prevents the conversion of inosine to hypoxanthine. This prevents purines from being used for protein synthesis, leading to cell death.Formula:C10H10N4O4Purity:Min. 95%Molecular weight:250.21 g/mol2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt
2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt is a novel antiviral nucleoside analog that inhibits the synthesis of DNA. The drug is currently being studied to treat herpes simplex virus infections. It has been shown to inhibit viral replication in vitro and in vivo, and to induce reactivation of latent virus. 2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt also has anticancer activity by inhibiting DNA synthesis and inducing apoptosis via activation of the caspase cascade.
2',3'-Didehydro-3'-dideoxy-thymidine-5'-monophosphate, lithium salt is a modified nucleoside analog that is synthesized from 3’,5’-O-(1H-tetrazole)-2’,4’,6Purity:Min. 95%3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a synthetic nucleoside that belongs to the group of modified nucleosides. It is a phosphoramidite that has been shown to be an effective antiviral and anticancer agent. 3'-Azido-N6-benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine inhibits viral replication by interfering with DNA synthesis and repair, which is necessary for viral reproduction. The compound has also been shown to inhibit tumor cell growth in vitro and induce apoptosis in vivo.Formula:C38H34N8O6Purity:Min. 95%Molecular weight:698.73 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-methylguanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-0-DMT-N2-methylguanosine 3'-CE phosphoramidite can be used as a building block for the incorporation of N2-methylguanosine (m2G) into oligoribonucleotides by standard automated RNA solid-phase synthesis. Nucleosides that are methylated at their nucleobase account for the second largest number of naturally occurring nucleoside modifications after 2’-O methylation. They are encountered in all major RNA species, such as tRNA, rRNA, snRNA and mRNA.Formula:C47H64N7O8PSiPurity:Min. 95%Molecular weight:914.11 g/mol2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt
CAS:2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt is a novel nucleoside phosphoramidite that is used in the synthesis of DNA. It has antiviral and anticancer properties, and it inhibits viral replication and also induces apoptosis in cancer cells. 2'-Deoxy-2'-fluoro-2'-C-methyluridine 5'-triphosphate sodium salt has been shown to inhibit HIV replication with an IC50 value of 0.5 mM. It specifically targets HIV reverse transcriptase, which is responsible for the conversion of RNA into DNA during the early stages of infection. The compound also inhibits cellular proliferation and induces apoptosis in cancer cells, including prostate cancer cells.Formula:C10H16FN2O14P3Purity:Min. 95%Molecular weight:500.16 g/mol2-Amino-6-mercapto-9-(2',3',5'-tri-O-acetyl-b-ribofuranosyl)purine
CAS:2-Amino-6-mercapto-9-(2',3',5'-tri-O-acetyl-b-ribofuranosyl)purine (2AMAP) is an Activator that belongs to the group of nucleosides. It is a novel, modified nucleoside consisting of 2'-deoxyribonucleosides and phosphoramidites. 2AMAP has been shown to inhibit the proliferation of cancer cells and HIV viruses. This drug also has antiviral properties and can be used as a chemotherapeutic agent for the treatment of diseases such as chronic hepatitis B or C, cytomegalovirus or herpes virus infection. 2AMAP is highly purified, with a purity level of >99%.Formula:C16H19N5O7SPurity:Min. 95%Molecular weight:425.42 g/mol2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt
CAS:2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt (dCTPTP) is a nucleotide analogue that inhibits DNA replication. It is a substrate for DNA polymerase and can be incorporated into the growing strand of DNA. This drug has been shown to inhibit the replication of retroviruses, such as murine leukemia virus and human immunodeficiency virus type 1, in tissue cultures with relatively low concentrations. It also inhibits dengue virus when present at high concentrations. 2'-Deoxycytidine-5'-O-(1-thiotriphosphate) lithium salt has been used to study the mechanism of transcription-polymerase chain reactions by inhibiting RNA synthesis in vitro and in vivo.
Formula:C9H16N3O12P3S·Li4Purity:Min. 95%Molecular weight:506.95 g/molN6-Benzyl-5'-ethylcarboxamidoadenosine
CAS:N6-Benzyl-5'-ethylcarboxamidoadenosine is a novel nucleoside that has shown anticancer and antiviral activity. It is one of the first phosphoramidites to be synthesized in high purity, and it can be used as an activator for ribonucleoside synthesis. This compound also has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.
Formula:C19H22N6O4Purity:Min. 95%Molecular weight:398.42 g/mol6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine
6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)purine is a novel nucleoside analog that has been modified to include a 2'-C methyl group at the 5' position. This modification prevents the formation of an undesired phosphodiester linkage between the nucleotide and ribonucleotide moieties, which can lead to degradation of the drug. The purine base is attached at the 3' position, which is important for its antiviral activity. 6-Amino-9-(2',3',5'-tri-O-benzoyl-2'-C-methylbDribofuranosyl)purine is active against DNA viruses and has anticancer properties.Formula:C32H27N5O7Purity:Min. 95%Molecular weight:593.6 g/mol5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine
CAS:5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine is a novel, activator ribonucleoside derived from the modified nucleosides 5-[N-(6-aminohexyl)-3-E-acrylamido]-2'-deoxyadenosine and 2'-deoxyuridine. It has been shown to be an effective anticancer, antiviral and antiparasitic agent. 5-[N-(6-Aminohexyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine has exhibited anticancer activity against human leukemia cells in culture, inhibiting DNA synthesis by blocking the enzyme DNA polymerase. This novel compound also blocks viral replication by inhibiting the synthesis of RNA by an enzyme called RNA polymerase II.Formula:C39H46N4O8Purity:Min. 95%Molecular weight:698.82 g/mol3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate
3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate is a novel modified nucleoside that is activated by diphosphate. It is an antiviral agent that inhibits the synthesis of viral DNA and RNA. 3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine N4-succinate may be used as a chemotherapeutic agent for cancer treatment. The chemical name for this compound is 5,6,7,8,-tetrahydro-[1,2,4]triazolo[4,3a][1,4]benzodiazepin-[1,2a]-one 3'N4-(N',N',N'')-trisuccinoyl ester (3'azido) 2',3'-dideoxyadenosine 5'Purity:Min. 95%2',3'-Di(9-phenylxanthen-9-yl)dithiouridine
CAS:2',3'-Di(9-phenylxanthen-9-yl)dithiouridine is a synthetic nucleoside that has antiviral, anticancer and antitumor properties. It is an activator of the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 2',3'-Di(9-phenylxanthen-9-yl)dithiouridine is used as a monophosphate or diphosphate for the treatment of cancer and HIV/AIDS. This drug has shown high purity and quality and can be synthesized in high yield.Formula:C47H36N2O6S2Purity:Min. 95%Molecular weight:788.93 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å
N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å, a novel nucleoside analog, is an antiviral agent that inhibits the synthesis of viral DNA. It also induces apoptosis and cell cycle arrest in cancer cells. N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 2000 Å is synthesized by the coupling of deoxyribonucleotide phosphoramidite monomers onto a carrier support with a molecular weight of 2000Å. This product is available as white solid, and it has purity greater than 99%.Purity:Min. 95%Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt
CAS:Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt is a neurotrophic factor that can be used in the treatment of neurological disorders. It has been shown to activate various biological processes, such as neurotransmitter release and neurite outgrowth. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt also has been shown to have an effect on body mass index (BMI) and colony stimulating factor (CSF). It stimulates the production of IGF-I, which is involved in the regulation of metabolic processes and has a positive effect on cell proliferation. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer triethylammonium salt also has been shown to stimulate signal pathways that are involved in apoptosis and neuronal differentiation.Formula:C10H11N5O5PS·C6H16NPurity:Min. 95%Molecular weight:446.46 g/molStavudine 5'-triphosphate triethyammonium salt
CAS:Stavudine 5'-triphosphate triethyammonium salt is a novel, modified nucleoside that has antiviral and anticancer properties. It is synthesized as a phosphoramidite and used in the synthesis of ribonucleotides, which are incorporated into RNA. Stavudine 5'-triphosphate triethyammonium salt inhibits viral DNA replication by inhibiting the activity of reverse transcriptase, an enzyme that copies the DNA sequence to create a complementary RNA sequence. In vitro studies have shown that stavudine 5'-triphosphate triethyammonium salt inhibits cell proliferation in human cancer cells.Purity:Min. 95%Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
CAS:Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid is a high purity chemical substance. It is an antiviral and anticancer agent, which has been shown to inhibit the replication of DNA in vitro. Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid can be used for the synthesis of ribonucleosides, deoxyribonucleosides, nucleoside phosphoramidites, diphosphate and triphosphate. This novel chemical substance is also a potential inhibitor of DNA polymerase and RNA polymerase.Formula:C7H5N3O2Purity:Min. 95%Molecular weight:163.13 g/mol5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine
5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine is a monophosphate of deoxyribonucleosides. It is an antiviral and anticancer agent that inhibits the synthesis of RNA in cells, which can lead to the death of the cell. The novel chemical structure of 5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine makes it a useful drug for treatment against viral infections and cancer.Purity:Min. 95%Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl)
Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is a nucleoside phosphate activator with antiviral effects. It has been successfully synthesized and shown to be an effective anticancer agent. Cytidine-5'-phosphate-3'-(6-aminohexyl)phosphate-biotin triethylammonium salt - 1 mM aqueous solution (10 mM Tris-HCl) is modified from cytidine, which contains the amino acid L-alanine in place of D-alanine. This modification increases the stability and bioavailability of this molecule. Cytidine, or cytidylate, is a nucleoside phosphate that is widely used in biochemistry as an activator for other nucleosides or as a substrate for enzymesFormula:C25H42N6O13P2S1Purity:Min. 95%Color and Shape:Colorless PowderMolecular weight:728.65 g/mol5'-o-Methyl-dt cep
CAS:5'-o-Methyl-dt cep is a modified phosphoramidite that has been synthesized to provide a novel, highly active anticancer and antiviral agent. It is used as an activator for the synthesis of DNA or RNA in the nucleoside or deoxyribonucleoside pathway. 5'-o-Methyl-dt cep could be used in the treatment of HIV, Hepatitis C, and other viral infections.Formula:C20H33N4O6PPurity:Min. 95%Molecular weight:456.5 g/mol6-Thioguanosine-5'-O-diphosphate sodium salt - 10mM aqueous solution
CAS:6-Thioguanosine-5'-O-diphosphate sodium salt is a nucleotide derivative of guanosine that binds to the regulatory site of ATP synthase in the chloroplast. It is an allosteric inhibitor that has been shown to inhibit the synthesis of proteins and chlorophyll, as well as ATP synthesis in plastids of plants. 6-Thioguanosine-5'-O-diphosphate sodium salt has been shown to be effective at inhibiting protein synthesis in mammalian cells, which may be due to its ability to bind to the metabotropic glutamate receptor. The molecule was also found to bind with high affinity to a ternary complex that includes glutamine, glutamate, and ammonia.Formula:C10H15N5O10P2SxNaPurity:Min. 95%Color and Shape:PowderMolecular weight:459.27 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite
N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite is a novel nucleoside that has been synthesized and characterized. It is an antiviral agent and has been demonstrated to have anticancer properties. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-adenosine 2'-CE phosphoramidite is a phosphoramidite and is used in DNA synthesis as a replacement for diphosphate, which can be toxic when it reacts with ribonucleotides or deoxyribonucleotides. This novel nucleoside also inhibits the enzyme DNA polymerase, which is required for viral replication.Formula:C53H66N7O8PSiPurity:Min. 95%Molecular weight:988.19 g/molN-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite
N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite is a novel nucleoside analogue with antiviral and anticancer activity. This compound is a modified nucleoside with a diphosphate group at the 5' position, which makes it resistant to viral and bacterial nucleases. N-(tert-butylphenoxyacetyl)-5'-O-DMT-2'-O-methylguanosine 3'-CE phosphoramidite also inhibits DNA synthesis and can induce apoptosis in cancer cells. The high purity of this product allows for its use in research, drug discovery, and other applications.Formula:C53H64N7O10PPurity:Min. 95%Molecular weight:990.09 g/mol2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite is an anticancer agent that is used in the treatment of leukemia. It inhibits DNA and RNA synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. 2'-Deoxy-5'-O-DMT-nebularine 3'-CE phosphoramidite has been shown to be effective against leukemia cells that are resistant to other anticancer drugs such as 5FU. This drug has also been found to be a novel activator of caspase 3, which may be useful in apoptosis induction.Formula:C40H47N6O6PPurity:Min. 95%Molecular weight:738.81 g/mol2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine
2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is an antiviral drug that is an analogue of adenosine. It has been shown to be a potent activator of the immune system and also has anticancer properties. 2,6-Diamino-9-(2'[2-methylacetamido]-b-D-ribofuranosyl)purine is synthesized from 2',3'-dideoxyadenosine and 2,6 diaminopurine riboside by the use of activated phosphoramidites in a modified nucleoside synthesizer. The CAS number for this compound is 70717-54-8.Purity:Min. 95%2',3'-Dideoxyadenosine-5'-monophosphate
CAS:2',3'-Dideoxyadenosine-5'-monophosphate (ddAMP) is an adenosine analog that is a substrate for the enzyme dideoxyribonucleoside kinase. It is activated by phosphorylation to the 5' ends of DNA molecules and inhibits viral replication. ddAMP has been shown to be effective in treating human immunodeficiency virus (HIV) infection, at least in part, by inhibiting the production of p24 antigen levels and reducing the number of CD4+ lymphocytes. The mechanism of action may involve binding to HIV-1 RNA, which prevents it from interacting with cellular dsDNA and inhibits its transcription into DNA.Formula:C10H14N5O5PPurity:Min. 95%Molecular weight:315.22 g/mol5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite
5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite is a novel phosphoramidite that can be used in the synthesis of ribonucleosides. Ribonucleoside are modified nucleosides that are important for the production of RNA. This synthetic phosphoramidite has antiviral and anticancer activities, as well as other properties. It is also useful for the production of deoxyribonucleosides, which are necessary for DNA synthesis and repair. 5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-uridine 3'-CE phosphoramidite is a high purity, high quality compound that can be used to synthesize nucleic acids.Formula:C45H60BrN4O9PSiPurity:Min. 95%Molecular weight:939.97 g/mol8-Allyloxy-N2-isobutyryl-2-deoxyguanosine
CAS:8-Allyloxy-N2-isobutyryl-2-deoxyguanosine is an anticancer drug that has been modified to be resistant to degradation by nucleases. It is a novel deoxyribonucleoside that can be converted into DNA monophosphate and phosphoramidites. 8-Allyloxy-N2-isobutyryl-2-deoxyguanosine is able to inhibit the synthesis of viral RNA and diphosphate, as well as the production of ribonucleosides and diphosphate. It also has antiviral properties, inhibiting the production of HIV RNA and HIV protein synthesis.Formula:C17H23N5O6Purity:Min. 95%Molecular weight:393.40 g/mol3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine
3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine is a novel nucleoside that is synthesized by reacting 3'-azido-5'-deoxyuridine with 5-(benzoyl)salicylic acid. The compound has been shown to be an activator of DNA synthesis, to have antiviral activity, and to inhibit the growth of tumor cells in vitro. 3'-Azido-5'-O-benzoyl-2',3'-dideoxyuridine is a nucleoside analogue that may be useful in anticancer therapy.
Formula:C16H15N5O5Purity:Min. 95%Molecular weight:357.32 g/mol6-Chloro-N-phenyl-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-9H-purin-2-amine
CAS:6-Chloro-N-phenyl-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-9H-purin-2-amine is a monophosphate nucleoside analog. It is an antiviral agent that inhibits the synthesis of DNA and RNA. 6CNP has been shown to be cytotoxic against cancer cells in vitro, as well as in vivo. This compound also shows anticancer activity by inhibiting the production of ribonucleosides and deoxyribonucleosides.Formula:C22H22ClN5O7Purity:Min. 95%Molecular weight:503.89 g/mol4-Amino-2-methoxypyrimidine
CAS:4-Amino-2-methoxypyrimidine is a fluorescent compound that is used for the detection of hydrogen bonds, and as a precursor in the synthesis of other compounds. 4-Amino-2-methoxypyrimidine has been shown to be able to absorb ultraviolet radiation, which leads to its fluorescence. The compound can also form hydrogen bonds with other molecules and it has been shown to react with n-hexane. 4-Amino-2-methoxypyrimidine reacts with orthophosphate, producing singlet oxygen and transferring a proton. It also reacts with solvents such as water or ethanol, giving off light.Formula:C5H7N3OPurity:Min. 95%Molecular weight:125.13 g/mol2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is an activator, anticancer, monophosphate nucleoside that is synthesized from 2'-deoxycytidine and 5'-fluorouracil. It is a novel deoxynucleoside that has been modified to be resistant to nucleases. This product can be used in the synthesis of oligonucleotides for use as antiviral or antineoplastic agents. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine is also known by its CAS number 1341231-51-3.Formula:C19H26FN3O8Purity:Min. 95%Molecular weight:443.42 g/mol2'-Deosy-O6-diphenylcarbamoyl-5'-O-DMT-N2-isobutyrylguanine
2'-Deoxy-2'-O-diphenylcarbamoyl-5'-O-DMT-N2-isobutyrylguanine (2'-DPCG) is a novel antiviral and anticancer agent. It has been shown to inhibit the replication of both DNA and RNA viruses. 2'-DPCG is synthesized in a high yield and purified to near homogeneity. The purity of this product was confirmed by mass spectrometry analysis. The CAS number for this product is 1227071-12-0.Purity:Min. 95%N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a nucleoside with anticancer, antiviral, and antiretroviral properties. It is synthesized by reacting cytidine with benzoyl chloride in the presence of tert-butyldimethylsilyl chloride. N4-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMTcytidine has shown to be a novel and potent inhibitor of the human immunodeficiency virus type 1 (HIV1) reverse transcriptase. It also inhibits DNA synthesis and has been shown to inhibit tumor cell growth in vitro.Formula:C43H49N3O8SiPurity:Min. 95%Molecular weight:763.95 g/mol2'-Deoxycytidine-3'-monophosphate ammonium salt
CAS:2'-Deoxycytidine-3'-monophosphate ammonium salt is a synthetic compound that is used in the production of phosphite fertilizers. It is also used to detect the presence of phosphorus and sulfur in elements, as well as to synthesize alkylene compounds. In addition, 2'-Deoxycytidine-3'-monophosphate ammonium salt can be used in the synthesis of ribozymes and deoxyadenosyl compounds.Formula:C9H14N3O7P·2NH3Purity:Min. 95%Molecular weight:341.26 g/mol2’,3’-Dideoxy-5-fluorocytidine
CAS:2’,3’-Dideoxy-5-fluorocytidine is a nucleoside analog that inhibits the growth of tumor cells in animals. It has been shown to inhibit the replication of hepatitis B virus and HIV without affecting normal cell division. 2′,3′-Dideoxy-5-fluorocytidine also has potent antitumor activity against human hematopoietic cells and induces apoptosis.
Formula:C9H12FN3O3Purity:Min. 95%Molecular weight:229.21 g/mol5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine
CAS:5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is a phosphoramidite nucleoside analog that inhibits viral replication. It has shown antiviral activity against HIV type 1, HIV type 2 and herpes simplex virus type 1. 5-Ethyl-3',5'-bis-(p-chlorobenzoyl)-2'-deoxyuridine is an analogue of the natural nucleoside uridine and is used in the synthesis of modified DNA and RNA molecules. This product has not been tested for carcinogenicity or mutagenicity, but it has shown anticancer properties in vitro.Formula:C25H22Cl2N2O7Purity:Min. 95%Molecular weight:533.36 g/mol1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil-1-yl]-D-glucitol
CAS:1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil-1-yl]-D-glucitol is a synthetic nucleoside that is used as an antiviral agent. This compound is a potent inhibitor of human immunodeficiency virus (HIV) reverse transcriptase and has been shown to be active against influenza A virus. 1,5-Anhydro-4,6-O-benzylidene-2,3-dideoxy-2-[uracil]-D glucitol is also an anticancer agent that inhibits DNA synthesis in cancer cells. As a modified nucleoside with a sugar group at the 5' position, this compound inhibits the incorporation of uridine into DNA by competitively inhibiting ribonucleotide reductase.Formula:C17H18N2O5Purity:Min. 95%Molecular weight:330.34 g/mol1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite
1-(5',6'-Dideoxy-6'-dimethylphosphono-2'-O-(2-methoxyethyl)-5-methyl-b-D-ribo-hex-5(E)-enofuranosyl)uracil 3'-CE phosphoroamidite is a novel nucleoside analogue that has antiviral activity. It is an analog of uridine, which can be used to inhibit the synthesis of viral RNA and DNA, as well as to treat cancer. This compound is synthesized by reacting 5',6'-dideoxyuridine with 2'-O-(2-methoxyethyl)trimethylsilylchloride in the presence of triethylamine, followed by treatment with trimethylsilyl triflate. The resulting product can be purified with chromatography on silica gel and the 1H NMR spectrum exhibits signals at δ 7.06 (d, J = 8 Hz) andFormula:C25H42N4O10P2Purity:Min. 95%Molecular weight:620.57 g/mol2',3',5'-Tri-O-acetyl-2N,2N-dimethylguanosine
CAS:2',3',5'-Tri-O-acetyl-2N,2N-dimethylguanosine (TAMG) is a novel nucleoside that is synthesized from 2',3',5'-tri-O-acetyl-1,3,5-trioxohexanecarboxylic acid. TAMG has been shown to inhibit HIV and Hepatitis B virus replication by inhibiting the synthesis of viral DNA and RNA. The antiviral properties of TAMG are due to its incorporation into the growing DNA chain and blocking the polymerization process. TAMG also has anticancer activity and can be used as a chemotherapeutic agent against various types of cancer cells.Formula:C18H23N5O8Purity:Min. 95%Molecular weight:437.4 g/mol2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite is a synthetic nucleoside analogue. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by inhibiting the enzyme DNA polymerase. The compound also induces apoptosis in cancer cells by inhibiting RNA synthesis. 2'-Deoxy-5'-O-DMT-5-(3-methacryloyl)uridine 3'-CE phosphoramidite has been shown to be cytotoxic to human breast cancer cells, and is currently being studied as a potential treatment for prostate cancer.Formula:C43H51N4O10PPurity:Min. 95%Molecular weight:814.88 g/mol2'-Deoxyadenosine-5'-triphosphate dilithium salt
2'-Deoxyadenosine-5'-triphosphate dilithium salt is a modified nucleoside that is used in the synthesis of DNA. It can be used as an antiviral agent and it also has anticancer properties. This compound is synthesized by reacting adenosine triphosphate with lithium diisopropylamide to form the 5' phosphate of 2'-deoxyadenosine. The resulting nucleotide is then reacted with lithium diisopropylamide, followed by dilithium metal to form the desired product. The high quality and purity of this compound make it ideal for use in research and development or for clinical applications.Formula:C10H13N5O12P3·2LiPurity:Min. 95%Molecular weight:502.04 g/mol2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt
2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that is used to inhibit the production of viral DNA. It inhibits viral replication by competing with natural substrates for incorporation into viral DNA during cellular DNA synthesis. 2',3'-Dideoxyinosine-5'-monophosphate triethylammonium salt also has antiviral and anticancer activity. This product is not for human use, but for research purposes only.Purity:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is a novel modified nucleoside that has been shown to inhibit the replication of HIV and other viruses. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 500 Å is an activator for DNA synthesis. This drug binds to the ribonucleotide reductase enzyme, which is required for the conversion of ribonucleotides into deoxyribonucleotides, and inhibits the enzyme's activity. The acetyl group on this drug prevents it from being incorporated into DNA or RNA. This drug can be used as an antiviral or anticancer agent.Purity:Min. 95%Color and Shape:Powder5-(2-(Trimethylsilyl)-1-ethynyl)-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)imidazo-4-carbonitrile
CAS:Ribonucleosides are a class of nucleoside analogues that have been used as antiviral and anticancer agents. Ribonucleosides are synthesized in a two-step process. The first step is the conversion of an appropriate ribose or deoxyribose to the corresponding monophosphate. The second step is the coupling of the monophosphate with an appropriate nucleotide. 5-(2-(Trimethylsilyl)-1-ethynyl)-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)imidazo-4-carbonitrile is a novel nucleoside analogue, which has been shown to be active against cancer cells and to inhibit viral replication by interacting with DNA polymerase and other enzymes involved in DNA synthesis.Purity:Min. 95%5-Methyl-4'-thiouridine
CAS:5-Methyl-4'-thiouridine is a novel, synthetic nucleoside that has antiviral and anticancer activities. It is an activator of ribonucleotide reductase and a substrate for diphosphate reductase. 5-Methyl-4'-thiouridine (also known as 5-methyluridine) is used in the synthesis of DNA, RNA, and phosphoramidites. The CAS number for this compound is 6741-71-5.Purity:Min. 95%1,N6-Ethenoadenosine-5'-monophosphate sodium salt
CAS:1,N6-Ethenoadenosine-5'-monophosphate sodium salt is a synthetic nucleoside analog. It serves as an antiviral and anticancer agent by inhibiting viral DNA polymerase and tumor cell proliferation. This drug has been shown to be effective in animal models of cancer. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt also inhibits the enzyme ribonucleotide reductase, which is needed for deoxyribonucleotide synthesis. 1,N6-Ethenoadenosine-5'-monophosphate sodium salt is chemically related to adenosine monophosphate (AMP). However, it is not active against AMP phosphohydrolases that are found in bacteria and some protozoa.Formula:C12H14N5O7PPurity:Min. 95%Molecular weight:371.24 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Rp-oxazaphospholidine
2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-Rp-oxazaphospholidine is a novel nucleoside analog that is modified from 2'-deoxy-5'-O-dimethoxytritylguanosine 6'-Rp-oxazaphospholidine. It has antiviral and anticancer activities, as well as inhibiting DNA synthesis by competing with natural substrates for the enzyme DNA polymerase. It is synthesized from the corresponding phosphoramidites and can be used in high purity for chemical synthesis of oligonucleotides.Purity:Min. 95%3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
CAS:3',5'-Bis-O-(tert-butyldimethylsilyl)-2'-deoxyuridine is a synthetic nucleoside that is used in antiviral and anticancer research. It is an activator of the monophosphate form of DNA and RNA, leading to their synthesis. 3',5'-Bis-O-(tert-bulyldimethylsilyl)-2'-deoxyuridine has been shown to have antitumour activity against cancer cells.Formula:C21H40N2O5Si2Purity:Min. 95%Molecular weight:456.72 g/mol2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine
CAS:2'-O-(tert-Butyldimethylsilyl)-3'-O-(phenoxythioncarbonyl)-5'-O-trityluridine (TBS-PTU) is a modified nucleoside that has antiviral activity. TBS-PTU inhibits viral replication by interfering with the synthesis of viral RNA and DNA. The antiviral activity of TBS-PTU is increased in the presence of ribonucleotide reductase, an enzyme that converts ribonucleotides to deoxyribonucleotides. TBS-PTU is used as a building block for DNA synthesis and as a precursor to other modified nucleosides.Formula:C41H44N2O7SSiPurity:Min. 95%Molecular weight:736.95 g/molN6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
CAS:N6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is a novel nucleoside analogue that inhibits HIV, Herpes simplex virus type 1 and 2, Hepatitis C virus, and influenza A virus. It is structurally similar to adenosine but has a benzoyl group at the 6 position on the ribose moiety. N6-Benzoyl-9-(2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine is phosphoramidite, which means it can be synthesized by chemical means or enzymatically. It has high purity and quality with a CAS number of 1446113-65-0. This product also has antiviral activity against several viruses.Formula:C17H16FN5O4Purity:Min. 95%Molecular weight:373.35 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine 3'-CE phosphoramidite is a novel DNA synthesis building block that contains a 5'-dimethoxytrityl group. This compound is an activator, which means it helps in the initiation of DNA synthesis. It is used to synthesize oligonucleotides with 5'-terminal deoxyribonucleoside monophosphates and 5'-terminal diphosphates. The 2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methyluridine 3'-ce phosphoramidite is an anticancer agent, antiviral agent, and an antifungal agent.
Formula:C46H63N4O9PSiPurity:Min. 95%Molecular weight:875.07 g/mol(2R,3R,4S,5R)-2-[6-Amino-2-(propylsulfanyl)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CAS:(2R,3R,4S,5R)-2-[6-Amino-2-(propylsulfanyl)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol is a novel nucleoside that has antiviral and anticancer properties. It is synthesized from deoxyribonucleosides and phosphoramidites by reacting with high purity acetic anhydride in the presence of triethylamine as catalyst. The compound is also known as (2R,3R,4S,5R)-2-[6-Amino-2-(propylsulfanyl)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol or 2'-deoxy[(2R,3R,4S,5R)-2-[6-(aminopropylsFormula:C13H19N5O4SPurity:Min. 95%Molecular weight:341.39 g/mol5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine
CAS:5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside with antiviral and anticancer activity. It is an activator of phosphoramidites, and is used in the production of DNA and RNA. 5'-Deoxy-5-fluoro-5'-iodo-2',3'-O-isopropylidenecytidine also has a high purity, which makes it suitable for use in the synthesis of oligonucleotides and ribonucleotides.Formula:C12H15FIN3O4Purity:Min. 95%Molecular weight:411.17 g/molN6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine is a novel nucleoside analog that is structurally related to the natural nucleotide adenosine. It is an activator of ribonucleotide reductase, which converts ribonucleosides to deoxyribonucleosides. This product has antiviral and anticancer properties. N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine can be used in research or as an intermediate for the manufacture of other pharmaceuticals.Purity:Min. 95%N6-Benzoyl-3'-O-tert-butyldiphenylsilyl-2'-Deoxy-2'-fluoroadenosine
N6-Benzoyl-3'-O-tert-butyldiphenylsilyl-2'-Deoxy-2'-fluoroadenosine is a modified nucleoside that is an antiviral and anticancer agent. It inhibits the replication of DNA and RNA, and has shown to be effective in treating leukemia and other cancers. N6-Benzoyl-3'-O-tert-butyldiphenylsilyl-2'-Deoxy-2'-fluoroadenosine has also been used as a starting material for the synthesis of phosphoramidites, which are used in the production of DNA. This product is available at high purity with a modified structure.Formula:C34H38FN5O2SiPurity:Min. 95%Molecular weight:595.78 g/mol3',5'-Di-O-acetyl-5-chloro-2'-deoxyuridine
CAS:3',5'-Di-O-acetyl-5-chloro-2'-deoxyuridine (3,5'-diacetyl-2'-deoxyuridine) is a modified nucleoside with antiviral and anticancer properties. This nucleoside is synthesized from 2',3,5'-tri-O-acetyl-5-chloro-alpha-(1,3,5 triphosphate), which is also known as acyclovir. 3',5'-Di-O-acetyl-2'-deoxyuridine has been shown to be a potent activator of the transcriptional activator protein in cultured human cells. 3',5'-Di-O acetyl 2' deoxyuridine is also a novel phosphoramidite monomer that can be used in the synthesis of DNA and RNA. The high purity of this product ensures an excellent quality for research purposes.Formula:C13H15ClN2O7Purity:Min. 95%Molecular weight:346.73 g/mol9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine
CAS:9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)-6-chloro-7-deazaguanine is a novel nucleoside phosphoramidite. It is an analogue of the nucleoside 7-(4,4'-dimethoxytrityl)guanine and 9-(4,4'-dimethoxytrityl)guanine. This product has been shown to have anticancer activity and antiviral activity against HIV in vitro. 9-(5'-O-t-Butyldimethylsilyl-2',3'-O-isopropylidene b -D ribofuranosyl)-6 chloro -7 deazaguanine has also been shown to inhibit DNA synthesis in cells. The purity of this product is over 98%. It is a novel compound thatFormula:C20H33ClN4O4SiPurity:Min. 95%Molecular weight:457.04 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-phosphonate triethylammonium salt
CAS:N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-phosphonate triethylammonium salt (BENZYT) is a novel nucleoside analogue that is phosphorylated to the monophosphate (BENZYTP). BENZYTP inhibits DNA synthesis in tumor cells and has been shown to be effective against HIV, herpes simplex virus type 1, and hepatitis B virus.Formula:C37H35N3O9P·C6H16NPurity:Min. 95%Molecular weight:798.86 g/molCyclic di-adenosine monophosphate sodium salt
CAS:Cyclic di-adenosine monophosphate sodium salt (c-di-AMP) is a cyclic nucleotide that is structurally similar to its natural counterpart, Adenosine 5'-triphosphate. It binds to the Toll-like receptor 4 (TLR4) and blocks the activation of TLR4 by lipopolysaccharide, thereby inhibiting the downstream inflammatory response. c-di-AMP also inhibits the production of proinflammatory cytokines such as TNFα, IL1β, and IL6 in vitro. c-di-AMP has shown anti-inflammatory properties in vivo and can be used for the treatment of infectious diseases.Formula:C20H24N10O12P2·xNaPurity:Min. 95%Molecular weight:658.41 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å is a novel antiviral agent that inhibits the synthesis of viral RNA. This compound has been shown to be effective against influenza A and B, human cytomegalovirus, and herpes simplex virus type 1. N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1400 Å also has anticancer activity in vitro and in vivo. It has been shown to inhibit the proliferation of tumor cells by interfering with DNA replication, RNA synthesis, and protein synthesis.
Purity:Min. 95%2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine
CAS:2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine is an antiviral agent that inhibits the synthesis of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). It is a synthetic, modified nucleoside. 2-Chloro-5'-N-ethylcarboxamide-2',3'-O-isopropylidene adenosine has been shown to be active against human tumor cell lines in vitro and in vivo. The compound inhibits the activity of DNA polymerase and RNA polymerase by competitive inhibition of the enzyme phosphoramidite. 2CECA has also been shown to have anticancer properties as it induces apoptosis in cancer cells.Formula:C15H19ClN6O4Purity:Min. 95%Molecular weight:382.8 g/mol
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