
Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3567 products of "Nucleosides"
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5'-O-DMT-4-thiouridine
<p>5'-O-DMT-4-thiouridine is a nucleoside analog that is used as a research tool in anticancer and antiviral studies. It is an activator of the phosphatase PP1 and has been shown to inhibit the growth of cultured human leukemia cells by inhibiting DNA synthesis. This compound has also been shown to be an inhibitor of HIV replication in vitro and in vivo, but it is not active against other viruses. 5'-O-DMT-4-thiouridine can be synthesized from uracil, 4-thiouracil, and DMT (dimethoxytrityl) using standard phosphoramidite chemistry. The purity of this compound is greater than 99%, and it can be obtained for use at a reasonable price.</p>Formula:C30H30N2O7SPurity:Min. 95%Molecular weight:562.64 g/mol3'-O-tert-Butyldimethylsilyladenosine
CAS:<p>3'-O-tert-Butyldimethylsilyladenosine is a synthetic nucleoside that is an antiviral agent with high purity. It has been shown to have anticancer properties and can be used as a deoxyribonucleoside activator or as a novel monophosphate nucleoside. 3'-O-tert-Butyldimethylsilyladenosine is also modified with an alkyl group for the phosphoramidite building block synthesis of DNA, RNA, and oligonucleotides. It has been shown to inhibit the synthesis of DNA and RNA by binding to the enzyme ribonucleotide reductase in cells.</p>Purity:Min. 95%7’-Hydroxy-N-Trityl-morpholino guanine
CAS:<p>Please enquire for more information about 7’-Hydroxy-N-Trityl-morpholino guanine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C29H28N6O3Molecular weight:508.57 g/mol7-Deaza-2'-C-methylguanosine
CAS:<p>7-Deaza-2'-C-methylguanosine is a nucleoside that is obtained from the synthesis of 7-deazaguanosine. It has antiviral activity and has been shown to be an activator for DNA synthesis. This compound is used as a monophosphate, diphosphate, or phosphoramidite in the synthesis of oligonucleotides. 7-Deaza-2'-C-methylguanosine has been shown to have anticancer properties, which may be due to its ability to inhibit ribonucleotide reductase and thus inhibit DNA synthesis.</p>Formula:C12H16N4O5Purity:Min. 95%Molecular weight:296.29 g/mol5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite
<p>5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral, anticancer and antimalarial activity. It is also used as a building block for the synthesis of oligonucleotides and in the modification of DNA, RNA and proteins. 5'-O-DMT-N4-benzoyl-5-methyl-(2'-O-4'-C-methylene)-cytidine 3'-CE phosphoramidite is an analogue of cytidine, which can be incorporated into DNA by means of enzymatic reactions. In addition to its antiviral, anticancer and antimalarial properties, it has been shown to have antiinflammatory effects. This drug is synthesized by chemical modification of cytosine, with 2′-, 4′-, or 6′ -</p>Purity:Min. 95%3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine
<p>3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine is a synthetic nucleoside. It is an activator of the immune system and has antiviral activities. 3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine is also a potent inhibitor of DNA and RNA polymerases, thereby preventing the synthesis of these nucleic acids. This drug has been shown to inhibit tumor cell growth in cultures of human cancer cells and has been used as a potential anticancer agent in clinical trials. The drug's activity as an immunomodulator is due to its ability to bind to lymphocytes, which leads to the production of cytokines that stimulate the immune system. 3',5'-Di-O-acetyl-N4-acetyl-2'-deoxycytidine also inhibits HIV replication by binding to viral reverse transcriptase and preventing it from copying the viral genome</p>Formula:C15H19N3O7Purity:Min. 95%Molecular weight:353.33 g/mol6-Chloro-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine
CAS:<p>6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine is a novel nucleoside analogue. It is synthesized by reacting 2,6-dichloro 9-(2'-C-methyl beta D ribofuranosyl) 9H purine with methyl bromoacetate in the presence of sodium methoxide in methanol. 6-chloro 9-(2'-C-methyl beta D ribofuranosyl) 9H purine has antiviral activity against DNA and RNA viruses that are sensitive to it. It is phosphoramidite and can be used for DNA synthesis.</p>Formula:C11H13ClN4O4Purity:Min. 95%Molecular weight:300.7 g/mol5'-Iodo-2',3'-dideoxycytidine
<p>5'-Iodo-2',3'-dideoxycytidine is a nucleoside analog that is used as an antiviral agent and an anticancer drug. It inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase, which is necessary for DNA replication. This compound also has a high quality and purity, as it is synthesized in a controlled environment. 5'-Iodo-2',3'-dideoxycytidine has shown to be effective against leukemia cells in culture and has been shown to inhibit the growth of cancer cells in animal models.<br>5'-Iodo-2',3'-dideoxycytidine has shown to be effective against leukemia cells in culture and has been shown to inhibit the growth of cancer cells in animal models.</p>Formula:C9H12N3O3IPurity:Min. 95%Molecular weight:337.11 g/molγ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution
<p>Please enquire for more information about γ-(2-Azidoethyl)-ATP sodium, 10 mM aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C12H19N8O13P3•NaxPurity:Min. 95%2'-Bromo-2'-deoxyadenosine-5'-[(β,γ)-imido]triphosphate triethylammonium salt - 10mM aqueous solution
CAS:<p>2'-Bromo-2'-deoxyadenosine-5'-[(beta,gamma)-imido]triphosphate triethylammonium salt (IDP) is a synthetic analog of adenosine that has been used as a bioreactor in tissue culture. IDP binds to the mineralocorticoid receptor and activates it, leading to increased levels of fatty acid synthesis in the blood sample. This drug has shown efficacy in treating cancer and inhibiting tumor growth in animal studies. IDP also has potential for use as an environmental pollutant due to its ability to be activated by wastewater treatment processes.</p>Formula:C10H16N6O11P3BrPurity:Min. 95%Molecular weight:569.09 g/mol8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione
CAS:<p>8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione is a monophosphate nucleotide analog that inhibits viral DNA polymerases. It is a novel and high quality nucleoside phosphoramidite. 8-(2-Deoxy-b-D-ribofuranosyl)-imidazo[1,2-a]-1,3,5-triazine-2,4(3H,8H)-dione is synthesized from 2'-deoxyribonucleosides and modified ribonucleosides. The CAS number for the compound is 35763855 2.</p>Formula:C10H12N4O5Purity:Min. 95%Molecular weight:268.23 g/mol5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodouridine
CAS:<p>5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodouridine is an antiviral agent that acts by inhibiting DNA polymerase, preventing the production of viral DNA. It has a high purity and is modified with tert-butyldimethylsilyl groups so it can be used in phosphoramidite synthesis. It also has a CAS number of 134218-81-8 and is synthesized using monophosphate, phosphoramidites, or nucleosides as starting materials.</p>Formula:C15H25IN2O5SiPurity:Min. 95%Color and Shape:PowderMolecular weight:468.37 g/molL-Adenosine 5'-triphosphate sodium salt
CAS:<p>L-Adenosine 5'-triphosphate sodium salt is a monophosphate, diphosphate, and triphosphate analog of adenosine that is used as an antiviral agent. L-Adenosine 5'-triphosphate sodium salt is a synthetic nucleoside that is modified at the ribose sugar to form a phosphoramidite. This modification increases the stability of the molecule and prevents hydrolysis by ribonucleases. L-Adenosine 5'-triphosphate sodium salt is also known as Ado-5'-P or ATPγS.</p>Formula:C10H12N5O13P3Na4Purity:Min. 95%Molecular weight:595.11 g/mol2'-Deoxy-2'-fluorocytidine-5'-monophosphate
CAS:<p>2'-Deoxy-2'-fluorocytidine-5'-monophosphate (2F-dFMP) is a synthetic nucleoside that is used in the treatment of cancer and as an antiviral agent. 2F-dFMP inhibits DNA synthesis by inhibiting DNA polymerase, which is needed for replication of the cell's genetic material. It also has anti-HIV activity and can be used to treat HIV infection. 2F-dFMP is phosphorylated to 2'-deoxy-2'-fluorocytidine 5'-triphosphate (2F-dCTP), which then competes with natural nucleotides for incorporation into DNA and RNA. This drug binds to the enzyme thymidylate synthase, preventing the formation of thymine monophosphate from erythronic acid.</p>Formula:C9H13FN3O7PPurity:Min. 95%Molecular weight:325.19 g/mol2'-13CUridine
CAS:<p>2'-13CUridine is a nucleoside that is a pyrimidine nucleoside. It is a structural analogue of cytidine and deamination. 2'-13CUridine has been used in the synthesis of anti-cancer drugs such as cytarabine and 5-flurouracil. Cytarabine, a purine analog, is an important component of chemotherapy for the treatment of leukemia, lymphoma, and other cancers.</p>Formula:CC8H12N2O6Purity:Min. 95%Color and Shape:PowderMolecular weight:245.19 g/mol6-Pyrrolidino-7-deazapurine
CAS:<p>6-Pyrrolidino-7-deazapurine is a monophosphate nucleoside, which is a synthetic nucleotide. It has been shown to activate DNA synthesis and inhibit the growth of tumor cells. 6-Pyrrolidino-7-deazapurine has also been shown to be active against viruses, such as herpes, by inhibiting their replication. This product is stable at room temperature for up to one year and can be stored at -20°C for up to three years. The purity of this product is >98% with no detectable impurities.</p>Formula:C10H12N4Purity:Min. 95%Molecular weight:188.23 g/mol2,3'-Anhydro-1-b-D-fructofuranosyluracil
CAS:<p>2,3'-Anhydro-1-b-D-fructofuranosyluracil is a novel nucleoside that is activated by phosphorylation. It is a potential antiviral and anticancer agent. This compound has shown to be an effective inhibitor of HIV replication in vitro. It has also been shown to inhibit the growth of human cancer cells in vitro and in vivo.</p>Formula:C10H12N2O6Purity:Min. 95%Molecular weight:256.21 g/mol5'-O-DMT-3'-O-hexylphthalimidouridine
<p>5'-O-DMT-3'-O-hexylphthalimidouridine is an antiviral and anticancer agent that is a nucleoside analog. It inhibits viral replication by preventing the production of RNA, which is necessary for the synthesis of DNA. It also prevents the proliferation of cancer cells and induces apoptosis by inhibiting DNA synthesis. 5'-O-DMT-3'-O-hexylphthalimidouridine is a monophosphate that has been modified to form a phosphoramidite. The synthesized product was purified to high purity and quality with a novel structure.</p>Formula:C44H45N3O10Purity:Min. 95%Molecular weight:775.86 g/molXanthosine-5'-monophosphate ammonium salt
CAS:<p>Xanthosine-5'-monophosphate ammonium salt is a monophosphate compound that is formed by the reaction of xanthosine and ammonium hydroxide. It has been shown to have an optimum concentration of 1 mM in dextran sulfate solutions and to be active against a range of bacteria at this concentration. The antimicrobial activity of xanthosine-5'-monophosphate ammonium salt is due to its inhibition of energy metabolism and synthesis, which leads to cell death. Xanthosine-5'-monophosphate ammonium salt also inhibits the production of tetracycline resistance in leukemic mice and k562 cells, which may be due to its ability to form a complex enzyme with tetracycline synthetase.</p>Purity:Min. 95%3’-Deoxy- 3'- methylguanosine
CAS:<p>3’-Deoxy-3'-methylguanosine is a nucleoside that is used in the synthesis of DNA. 3’-Deoxy-3'-methylguanosine is a monophosphate that can be obtained from the phosphoramidites, which are intermediates in the chemical synthesis of nucleotides. 3’-Deoxy-3'-methylguanosine is an activator for DNA polymerases and has been shown to have antiviral, anticancer, and antifungal properties. It has also been shown to be cytotoxic against leukemia cells. 3’-Deoxy-3'-methylguanosine is a novel nucleoside with modified properties.</p>Formula:C11H15N5O4Purity:Min. 95%Molecular weight:281.27 g/mol2',3',5-Tri-O-acetyl-2-chloroadenosine
CAS:<p>2',3',5-Tri-O-acetyl-2-chloroadenosine is a modified nucleoside that has been shown to be a potent activator of the transcriptional activator protein 2 (AP2) and AP1. The ribonucleosides are synthesized by phosphoramidite chemistry and are prepared as monophosphate or diphosphate derivatives. 2',3',5-Tri-O-acetyl-2-chloroadenosine also has antiviral activity against herpes simplex virus type 1 (HSV1). This drug is highly purified and can be used in high quality applications, such as anticancer and antiviral treatments.</p>Formula:C16H18ClN5O7Purity:Min. 95%Molecular weight:427.8 g/molGuanosine 5'-triphosphate
CAS:<p>Guanosine 5'-triphosphate (GTP) is a nucleotide that is involved in many cellular processes including transcription, protein synthesis, and intracellular signaling. GTP binds to the enzyme guanine nucleotide-binding proteins and regulates the activity of certain enzymes. One such enzyme is adenylyl cyclase, which converts ATP into cAMP. GTP also activates other enzymes that are involved in signal transduction pathways, such as phospholipase C-β1 and phospholipase D. The antimicrobial agents can inhibit these enzymes, thereby preventing bacterial growth and replication.</p>Formula:C10H16N5O14P3Purity:Min. 95%Molecular weight:523.18 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite
<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite is an activator that is used in the synthesis of DNA, RNA, and other nucleic acids. It has antiviral, anticancer, and antimicrobial activities. N4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite is a novel compound that has been modified to improve its activity as an activator. This activator is provided at high purity and is suitable for research purposes.</p>Formula:C46H51IN5O8PPurity:Min. 95%Color and Shape:PowderMolecular weight:959.83 g/molGuanosine-5'-monophosphate triethylammonium salt
CAS:<p>Guanosine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that is an activator of DNA. It is used in antiviral and anticancer treatments, as well as in the synthesis of deoxyribonucleosides. This product has been shown to have high purity and high quality.</p>Formula:C10H14N5O8P•C6H15NPurity:Min. 95%Molecular weight:464.41 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt
<p>N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt is a modified nucleotide that has been shown to have anticancer and antiviral activity. N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-O succinate TEA salt inhibits the synthesis of viral DNA and also inhibits the production of DNA in tumor cells. This compound is a phosphoramidite, which is an activated ester of a nucleoside with a phosphate group. The active form of this drug is adenosine triphosphate (ATP), which acts as an activator for DNA synthesis, leading to the production of deoxyribonucleosides and monophosphate, which are necessary for DNA replication.</p>Purity:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine
<p>N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine is a nucleoside analog that is used as an antiviral, anticancer, and antiretroviral agent. It is a potent inhibitor of HIV replication in vitro and in vivo. N4-Acetyl-2'-deoxy-5'-O-DMT-5-methylcytidine inhibits the activity of viral reverse transcriptase and DNA polymerase by binding to their RNA template strand. The drug shows efficacy against leukemia cells in vitro and against murine leukemia L1210 cells in vivo. Treatment with N4-acetyl-2'-deoxy-5'-O-DMT cytidine has been shown to reduce the size of tumors in mice with fibrosarcoma, melanoma, or glioma xenografts. N4 acetyl 2’ deoxy 5’ O DMT cytidine is also</p>Formula:C33H35N3O7Purity:Min. 95%Molecular weight:585.65 g/mol3’-O-(2-Methoxyethyl)adenosine
CAS:<p>3’-O-(2-Methoxyethyl)adenosine is a nucleoside, a kind of building block for DNA. It is an antiviral agent that inhibits viral replication by preventing the incorporation of viral nucleic acid into host DNA. 3’-O-(2-Methoxyethyl)adenosine also has anticancer properties, which makes it useful as a chemotherapeutic agent. 3’-O-(2-Methoxyethyl)adenosine is synthesized from adenosine monophosphate in two steps: first, the methoxy group is attached to the 2’ position of the ribose sugar by phosphoramidite chemistry; second, the 5' hydroxyl group is oxidized to form the phosphate ester.</p>Formula:C13H19N5O5Purity:Min. 95%Molecular weight:325.32 g/mol2-Chloro-6-(2'-deoxy-b-D-ribofuranosyl)-3,5-diaminopyrazine
CAS:<p>2-Chloro-6-(2'-deoxy-b-D-ribofuranosyl)-3,5-diaminopyrazine is a modified nucleoside that can be used to synthesize DNA and RNA. It is an activator that activates the phosphoramidite coupling reaction of the synthesis of DNA. 2-Chloro-6-(2'-deoxy-b-D-ribofuranosyl)-3,5-diaminopyrazine has been shown to have anticancer and antiviral activities in vitro, but no in vivo data are currently available. It also has high purity and high quality.</p>Formula:C9H13ClN4O3Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:260.68 g/molL-Inosine
CAS:<p>L-Inosine is a purine nucleoside that is found in plants and animals. It is an intermediate in the pentose phosphate pathway and can be synthesized from the amino acid L-lysine. L-Inosine has been shown to inhibit the growth of trichomonas vaginalis and giardia, but not uninfected human erythrocytes. The mechanism of action of L-Inosine is not well understood, but it may have a role in transporting adenosine into cells. The oral bioavailability of L-Inosine is low due to its rapid conversion to l-adenosine by nonsaturable enzymes. L-Inosine does not appear to be a substrate for transport across mammalian cells, but it does act as a competitive inhibitor for glucose transport.</p>Formula:C10H12N4O5Purity:Min. 95%Color and Shape:Off-White SolidMolecular weight:268.23 g/mol1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine
<p>1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine is a synthetic nucleoside that acts as an activator of DNA synthesis and inhibits viral replication. It is used in the treatment of cancer and antiviral therapy. 1-(2'-Deoxy-2'-chloro-b-L-arabinofuranosyl)-thymine is also used as a building block for the modification of other nucleosides, including deoxyribonucleosides, ribonucleosides, and nucleotides. The drug is available in high purity at a low cost.</p>Formula:C10H13ClN2O5Purity:Min. 95%Molecular weight:276.67 g/molAdenosine HCl
CAS:<p>Adenosine is a nucleoside that is found in all cells. It plays an important role in the formation of ATP and as a neurotransmitter. Adenosine also acts on a receptor to promote vasodilation, improve cardiac contractility, and increase cardiac output. Adenosine has been found to be effective in preventing congestive heart failure in rats with myocardial infarction. In humans, adenosine has been shown to have beneficial effects on metabolic disorders such as diabetes mellitus and diabetic neuropathy. Adenosine HCl is an acid salt of adenosine that can be used for the treatment of coronary artery disease.</p>Formula:C10H13N5O4·HClPurity:Min. 95%Molecular weight:303.7 g/mol2-Iodo-2',3'-O-isopropylideneadenosine
CAS:<p>2-Iodo-2',3'-O-isopropylideneadenosine is a phosphoramidite nucleoside that is used for the synthesis of oligonucleotide DNA. It has antiviral and anticancer properties, as well as a novel chemical structure. 2-Iodo-2',3'-O-isopropylideneadenosine has been synthesized in high purity and quality. It is also available in CAS No. 141018-25-9.</p>Formula:C13H16IN5O4Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:433.21 g/molN-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester
CAS:<p>N-(2'-Deoxy- 2', 2'- difluorocytidine 5'-P- phenyl phosphate) L- alanine benzyl ester, also known as Acelarin, is primarily used in cancer treatment, including leukemia and solid tumors.</p>Formula:C25H27F2N4O8PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:580.47 g/mol3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine
<p>3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine is a novel nucleoside analogue with anticancer activity. 3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine is a modified deoxyribonucleoside monophosphate, which is activated by phosphorylation to the corresponding diphosphate form and then converted to an antiviral agent. 3'-O-Acetyl-5'-O-DMT-2'-O-methyuridine has been shown to have antiviral activity against herpes simplex virus type 1 (HSV1) and Epstein Barr virus (EBV). This compound also inhibits the proliferation of human cancer cells in vitro and in vivo.</p>Formula:C33H34N2O9Purity:Min. 95%Molecular weight:602.63 g/mol3',5'-O-(Di-tert-butylsilanediyl)uridine
CAS:<p>3',5'-O-(Di-tert-butylsilanediyl)uridine is a novel antiviral agent that is synthesized from uridine and has been shown to be effective against herpes simplex virus. This compound was also shown in vitro to inhibit the replication of human immunodeficiency virus type 1 (HIV-1). 3',5'-O-(Di-tert-butylsilanediyl)uridine binds to single stranded DNA, preventing the synthesis of DNA by the viral enzyme reverse transcriptase. It also inhibits the production of viral proteins by binding to viral RNA polymerase. This drug may also have anticancer activity due to its ability to inhibit ribonucleotide reductase, an enzyme required for DNA synthesis.</p>Purity:Min. 95%5-Methyl-2',3'-stannyluridine
<p>5-Methyl-2',3'-stannyluridine is a nucleoside analog that is a potent inhibitor of viral replication and can be used for the treatment of HIV. It has been shown to inhibit the activity of RNA polymerase, thereby preventing transcription and replication. 5-Methyl-2',3'-stannyluridine also inhibits DNA synthesis by inhibiting the activity of DNA polymerase. This drug also acts as an antitumor agent and has been shown to inhibit tumor growth in animal models. The high purity of this drug makes it suitable for use in pharmaceutical applications.<br>5-Methyl-2',3'-stannyluridine is a modified nucleoside that has been modified with a stannyl group at the 2' position on the sugar moiety and an allyl group at the 3' position on the sugar moiety. The phosphoramidites are synthesized from 5-methyl-2',3'-stannyl</p>Purity:Min. 95%o-Topolin riboside-5'-monophosphate sodium salt
CAS:<p>O-topolin riboside-5'-monophosphate sodium salt is a phosphoramidite that has antiviral, anticancer and activator properties. It is synthesized from o-topolin riboside, which is a novel modified nucleoside. O-topolin riboside-5'-monophosphate sodium salt binds to the DNA strand and inhibits RNA synthesis. This prevents the production of proteins vital for cell division.</p>Formula:C17H18N5Na2O8P·H2OPurity:Min. 95%Molecular weight:515.32 g/mol2-Methylaminoadenosine
CAS:<p>2-Methylaminoadenosine is a nucleoside that is the product of the action of adenosine deaminase on 2-aminoadenosine. It is used in diagnostic assays to differentiate between n6-methyladenosine and deoxyadenosine in DNA, RNA, or serum samples. It has been shown to have an interaction with fatty acids and their derivatives and sequences in tissues. In addition, it has been shown to have specificities for cardiac tissue and a flow rate that is constant.</p>Formula:C11H16N6O4Purity:Min. 95%Molecular weight:296.28 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine
<p>2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine is a novel antiviral drug that has been shown to be active against influenza, herpes, and HIV. It belongs to the class of deoxyribonucleosides and is ribonucleotide analogs. 2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine inhibits viral replication by interacting with viral DNA polymerase, preventing the extension of viral DNA chains by blocking the incorporation of nucleotides into the growing strand. The enzyme activity of 2'-deoxy-N2-isobutyrylguanosine is activated by phosphoramidites in vitro.</p>Formula:C19H25N5O7Purity:Min. 95%Molecular weight:435.43 g/mol6-Benzylamino-9-(a-D-glucopyranosyl)purine
CAS:<p>6-Benzylamino-9-(a-D-glucopyranosyl)purine is a novel nucleoside phosphoramidite that has been synthesized as an intermediate for anticancer therapy. It is a monophosphate, which has antiviral and antifungal activity. 6-Benzylamino-9-(a-D-glucopyranosyl)purine is a synthetic nucleoside with a novel structure, which inhibits the synthesis of DNA and RNA. This drug also has ribonucleotide reductase inhibitory activities.</p>Formula:C18H21N5O5Purity:Min. 95%Molecular weight:387.4 g/mol2',3'-Dideoxy-3'-fluoroadenosine
CAS:<p>2',3'-Dideoxy-3'-fluoroadenosine (ddFdA) is an antiviral drug that has been shown to be effective against HIV and other viruses. It is a synthetic nucleoside analogue of the natural purine adenosine. ddFdA inhibits the synthesis of viral RNA and DNA by competitively inhibiting the enzyme ribonucleotide reductase, thereby blocking DNA synthesis. The drug has shown significant activity in humans with immunodeficiency, but also has toxic effects on lymphocytes. ddFdA is synthesised from 2',3'-dideoxyadenosine (ddAdo), which is produced by the action of adenosinase on adenosine. In humans, ddFdA is converted to dideoxyadenosine triphosphate (ddATP), which inhibits cellular proliferation.</p>Formula:C10H12FN5O2Purity:Min. 95%Molecular weight:253.23 g/mol6-Chloro-7-deaza-9-(5'-O-tert-butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)purine
CAS:<p>6-Chloro-7-deaza-9-(5'-O-tert-butyldimethylsilyl-2',3'-O-isopropylidene-b-D-ribofuranosyl)purine is a modified nucleoside that is used as an antiviral agent. It acts by inhibiting viral DNA polymerase to prevent the synthesis of viral DNA, which prevents virus replication and the spread of infection. 6CDAZP has been shown to be effective against Ebola and influenza viruses.</p>Formula:C20H30ClN3O4SiPurity:Min. 95%Color and Shape:Colourless to pale yellow oil.Molecular weight:440.02 g/molStavudine 5'-monophosphate sodium salt - 10 mM aqueous solution
<p>Stavudine is a nucleoside analog that is phosphorylated by cellular enzymes to the corresponding monophosphate. Stavudine is an activator of DNA synthesis and has been shown to be effective against cancer cells in vitro. It is also active against HIV-1, which has been shown in vitro to inhibit the production of viral DNA and RNA. Stavudine's antiviral activity may be due to its ability to inhibit the synthesis of viral DNA, RNA, or both. This drug can also be used as a nucleotide precursor for oligonucleotide synthesis.</p>Formula:C10H13N2O7P·xNaPurity:Min. 95%Molecular weight:304.19 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine 3'-CE phosphoramidite
CAS:<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine 3'-CE phosphoramidite is a novel DNA synthesis building block that contains a 5'-dimethoxytrityl group. This compound is an activator, which means it helps in the initiation of DNA synthesis. It is used to synthesize oligonucleotides with 5'-terminal deoxyribonucleoside monophosphates and 5'-terminal diphosphates. The 2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methyluridine 3'-ce phosphoramidite is an anticancer agent, antiviral agent, and an antifungal agent.</p>Formula:C46H63N4O9PSiPurity:Min. 95%Molecular weight:875.07 g/mol2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt - 100mM aqueous solution
CAS:<p>2'-Deoxy-2'-fluorouridine-5'-triphosphate sodium salt is an antibacterial agent with a potent antibacterial activity. It has been shown to be active against Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis. It also inhibits the synthesis of uronic acid and butyric acid, which are components of the bacterial cell wall. In addition, 2'-deoxy-2'-fluorouridine-5'-triphosphate sodium salt is able to inhibit nucleotidylyltransferase, which is an enzyme involved in the biosynthesis of fatty acids in bacteria.</p>Formula:C9H14FN2O14P3·NaPurity:Min. 95%Molecular weight:509.12 g/mol6-Methyl-thio-guanosine
CAS:<p>6-Methyl-thio-guanosine is a guanine analog that has been used for the treatment of asthma. It was found to be effective in reducing the number of neutrophils and responsiveness of these cells to stimuli. 6-Methyl-thio-guanosine is able to reduce the number of neutrophils in the airway and decrease the amount of sputum produced by patients with chronic obstructive pulmonary disease. 6-Methyl-thio-guanosine also prevents the release of mediators from these cells, which are important in inflammation. This drug has been shown to have an effect on bronchial epithelial cells, slowing their growth and increasing their ability to resist damage.<br>6-Methyl-thio-guanosine can be administered by inhalation or orally, through microlenses or expansion devices, or by suctioning bronchial secretions. Treatment may also involve injection directly into lung tissue using a bron</p>Formula:C11H15N5O4SPurity:Min. 95%Molecular weight:313.33 g/mol2'-Deoxy-5'-O-DMT-guanosine
CAS:<p>2'-Deoxy-5'-O-DMT-guanosine is a purine nucleoside that is converted to 2'-deoxy-5'-O-DMT-adenosine by the enzyme deoxyadenosyltransferase. This conversion is necessary for the synthesis of adenosylcobalamin, which is essential for the methylation of homocysteine to methionine. 2'-Deoxy-5'-O-DMT-guanosine has been shown to have cancer chemopreventive effects in vitro and in vivo. It also has been shown to enhance dna hybridization and hydrophobic interactions with cancerous cells, which may be due to its ability to inhibit gene expression.</p>Formula:C31H31N5O6Purity:Min. 95%Molecular weight:569.61 g/mol(5'S)-2'-Deoxy-8,5'-cycloadenosine
CAS:<p>(5'S)-2'-Deoxy-8,5'-cycloadenosine is a nucleoside analog that blocks the synthesis of DNA. It is a glycosylated nucleoside that contains an 8-carbon fatty acid chain linked to the 5’ carbon of the sugar ring. This compound is formed from the reaction of (5'S)-2'-deoxyadenosine and dicyclohexylcarbodiimide. The biological properties of this drug are not well understood, but it has been shown to be reactive with physiological levels and able to induce neuronal death in an experimental model. The mechanism for this effect is unknown, but may involve intramolecular hydrogen bonding or hydrolysis by esterases. A molecular docking analysis was performed to study the binding affinity between (5'S)-2'-deoxy-8,5'-cycloadenosine and human mda-mb-231 breast cancer cells. This analysis showed that wild</p>Formula:C10H11N5O3Purity:Min. 95%Molecular weight:249.23 g/mol2-tert-Butylpyrimidine-5-carbaldehyde
CAS:<p>2-tert-Butylpyrimidine-5-carbaldehyde (2BP) is a potent, selective inhibitor of DNA polymerase that is expressed in the tibia during bone development. 2BP has been shown to inhibit platelet-derived growth factor (PDGF)-induced angiogenesis in mouse calvaria and animal research models. This compound also inhibits the proliferation of basic fibroblasts and cancer cells in vitro.</p>Formula:C9H12N2OPurity:Min. 95%Molecular weight:164.2 g/mol2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS:<p>2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside analog that is a potent activator of the immune system. It is a novel synthetic compound with high purity and high quality. This compound has antiviral effects against HIV and other viruses. It also has anticancer properties, which are thought to be due to its ability to inhibit DNA synthesis in tumor cells.</p>Formula:C24H17CI2FN4O5Purity:Min. 95%Molecular weight:531.33 g/mol3'-Deoxy-3',4'-didehydro-CTP
CAS:<p>3'-Deoxy-3',4'-didehydro-CTP is a nucleoside analog. It is a novel, high quality, high purity and synthetic compound with antiviral and anticancer activities. 3'-Deoxy-3',4'-didehydro-CTP inhibits the synthesis of DNA by specifically inhibiting the activity of DNA polymerase. The IC50 value for this compound is 12.5 μM against herpes simplex virus type 1 (HSV-1) in vitro.</p>Formula:C9H14N3O13P3Purity:Min. 95%Molecular weight:465.14 g/mol5-Bromouridine-5'-monophosphate
CAS:<p>5-Bromouridine-5'-monophosphate is a nucleoside analog of uridine. It is an antiviral and antineoplastic agent that inhibits the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. This enzyme catalyzes the conversion of ribonucleosides to diphosphates, which are precursors for DNA and RNA synthesis. 5-Bromouridine-5'-monophosphate has been shown to be effective against some cancer cells in vitro and in vivo, but has not been tested on humans.</p>Formula:C9H12BrN2O9PPurity:Min. 95%Molecular weight:403.08 g/mol5'-Tosyl-2'-deoxyadenosine
CAS:<p>5'-Tosyl-2'-deoxyadenosine is a synthetic, novel nucleoside that has antiviral and anticancer activity. It is an activator of DNA synthesis and inhibits protein synthesis by blocking the enzyme ribonucleotide reductase. 5'-Tosyl-2'-deoxyadenosine is not active against Mycobacterium tuberculosis or Mycobacterium avium complex due to the lack of phosphoramidite incorporation into DNA. 5'-Tosyl-2'-deoxyadenosine is a high purity, high quality product that can be used as an antiviral agent or anticancer drug.</p>Purity:Min. 95%2'-Methyl-adenosine-(Bz)-succinyl-CPG; 500 Å (RNA)
<p>2'-Methyl-adenosine-(Bz)-succinyl-CPG; 500 Å (RNA) is a synthetic nucleotide that has antiviral and anticancer properties. It is a novel nucleotide with the phosphate group at the 2' position of the ribose sugar, which can be phosphorylated to form monophosphate or diphosphate. This product is highly purified and has been shown to have antiviral activity against HIV and anticancer activities in vitro.</p>Purity:Min. 95%6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:<p>6-(Benzylamino)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (BMPT) is a synthetic cytokinin that belongs to the group of 6-benzylaminopurines. BMPT is an inhibitor of cytokinin receptor kinases, as it is a benzyl uracil derivative. BMPT can be used as a building block for the synthesis of other compounds and has been used as an inhibitor of cell growth in various organisms.</p>Formula:C12H13N3O2Purity:Min. 95%Molecular weight:231.25 g/mol2',3'-Dithiouridine
CAS:<p>2',3'-Dithiouridine is a triamide that is synthesized from uridine and chloroacetic acid. The dimeric form of this compound has been shown to be the most stable and yields are high. 2',3'-Dithiouridine can be prepared by the reaction of uridine with chloroacetyl chloride in DMSO at room temperature. The disulfide linkage between the two thiouridines is stereospecifically oriented in a cis conformation. The synthesis of 2',3'-dithiouridine from uridine and chloroacetic acid is achieved by an efficient procedure that gives high yields. This synthetic pathway also produces a crystalline, cyclic, sodium salt form of 2',3',4'-trihydroxypentane-1,5-dione that has not been previously reported.</p>Formula:C9H12N2O4S2Purity:Min. 95%Molecular weight:276.33 g/mol5'-O-Acetyllamivudine
CAS:<p>5'-O-Acetyllamivudine is an antiviral agent that has been shown to have antiretroviral activity against HIV-1 and influenza A virus. It is a nucleoside analog that inhibits the synthesis of viral DNA by competitively inhibiting the enzyme DNA polymerase. 5'-O-Acetyllamivudine is also used as an anticancer drug, which may be due to its ability to inhibit DNA replication in tumor cells.</p>Formula:C10H13N3O4SPurity:Min. 95%Molecular weight:271.29 g/mol4-(4-Chlorophenyl)pyrimidine-2-thiol
CAS:<p>4-(4-Chlorophenyl)pyrimidine-2-thiol is an anti-cancer drug that is used in the treatment of ovarian cancer. It has been shown to be effective against cancer cells by interfering with the DNA replication process. 4-(4-Chlorophenyl)pyrimidine-2-thiol binds at the active site of topoisomerase II, which is involved in the process of transcription and replication. This drug also has been shown to induce apoptosis in fibroblast cells by inhibiting DNA synthesis and protein synthesis. 4-(4-Chlorophenyl)pyrimidine-2-thiol has a molecular weight of 181.24 g/mol and is soluble in water, methanol, and ethanol. The colorimetric assay for this compound has a detection limit of 1 µg/mL.</p>Purity:Min. 95%Cytidine 3',5'-bisphosphate sodium
CAS:<p>Cytidine 3',5'-bisphosphate sodium is a phospholipid that is found in the cell membrane of gram-positive bacteria. Cytidine 3',5'-bisphosphate sodium has been shown to be produced by the enzyme phosphatidylcholine synthase, which converts phosphatidylethanolamine and cytidine 5'-monophosphate into phosphatidylcholine and cytidine 3',5'-bisphosphate. The presence of this compound in the cell membrane may be an indication of long-term survival and growth under laboratory conditions. It is also present in the ribosomal RNA of type strain organisms.</p>Formula:C9H15N3O11P2•NaxPurity:Min. 95%Molecular weight:403.18 g/molL-Thymidine-5'-monophosphate sodium salt
<p>L-Thymidine-5'-monophosphate sodium salt is a synthetic nucleoside that is used as an antiviral agent. L-Thymidine-5'-monophosphate sodium salt has been shown to have high antiviral activity in vitro against human herpesvirus type 1, and in vivo against foot-and-mouth disease virus. The drug also inhibits the synthesis of DNA and RNA by inhibiting the enzyme ribonucleotide reductase. L-Thymidine-5'-monophosphate sodium salt acts as a phosphate donor for the phosphoramidite method of oligonucleotide synthesis. This novel nucleoside can be used in anticancer therapy due to its ability to inhibit DNA synthesis.</p>Purity:Min. 95%2-(Butylthio)pyrimidine-5-carbaldehyde
CAS:<p>2-(Butylthio)pyrimidine-5-carbaldehyde (BTPCA) is a neutralizing agent that inhibits the proliferation of cancer cells by binding to their cell membranes. It binds to the membrane and blocks the cyclic AMP receptor, thereby inhibiting the growth of cells. BTPCA has been shown to be effective in killing CD4+ T cells and may have therapeutic potential for autoimmune diseases. BTPCA also has diagnostic potential, as it can be used to detect epidermal growth factor receptors on cell membranes.</p>Formula:C9H12N2OSPurity:Min. 95%Molecular weight:196.27 g/mol2'-Cytidylic acid
CAS:<p>2'-Cytidylic acid is a nucleoside monophosphate that plays an important role in various biological processes. It has been used in the development of heparin and enoxaparin, which are anticoagulants used to prevent blood clots. 2'-Cytidylic acid has also been found in chitin, xyloglucan, and psyllium, where it acts as a signaling molecule involved in apoptosis and cell differentiation. This compound has been shown to modulate the activity of kinases and ion channels, including potassium channels. However, excessive intake of 2'-Cytidylic acid can cause bleeding due to its anticoagulant properties. Additionally, there is some evidence suggesting that this compound may have anti-cancer effects through its ability to inhibit cell growth and induce apoptosis. Heparin sodium containing 2'-Cytidylic acid is widely used in clinical practice for its anticoagulant properties.</p>Formula:C9H14N3O8PPurity:Min. 95%Molecular weight:323.2 g/molNonadecanoyl coenzyme A
CAS:<p>Nonadecanoyl coenzyme A is a fatty acid that is produced by the bovine liver and has been shown to have anabolic effects. Nonadecanoyl CoA is involved in the synthesis of various lipids, such as phospholipids, cholesterol, and glycolipids. It also plays a role in biosynthesis of fatty acids and in regulating ATP production. Nonadecanoyl CoA is synthesized from acetate by the enzyme acetyl-CoA carboxylase (ACC). ACC catalyzes the conversion of acetyl-CoA to malonyl-CoA, which can then be used for fatty acid synthesis. Nonadecanoyl CoA has been found to play an important role in regulating mitochondrial function through its ability to activate long-chain acyl-CoAs desaturase (LCAD). LCAD converts long-chain acyl-CoAs into their corresponding dicarboxylic acids.</p>Formula:C40H72N7O17P3SPurity:Min. 95%Molecular weight:1,048.02 g/mol3',5'-Di-O-acetyl-N4-benzoyl-2'-deoxycytidine
<p>3',5'-Di-O-acetyl-N4-benzoyl-2'-deoxycytidine is a novel, phosphoramidite monophosphate nucleoside. It is synthesized by reacting deoxydinucleosides with 3',5'-di-O-acetyl-N4-benzoyl-2'-deoxycytidine in the presence of a coupling agent. The product has been shown to be an excellent activator for DNA polymerases and may have antiviral effects. The chemical name of this compound is 2',3'-dideoxyadenosine 5' -triphosphate N4 -(beta, beta, beta, beta,-triethoxypropionyl) benzoyl ester.</p>Formula:C20H21N3O7Purity:Min. 95%Molecular weight:415.41 g/molBiotin-5-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution
<p>Biotin-5-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is a modified nucleoside with antiviral activity. It is a phosphoramidite that can be used for the synthesis of DNA, RNA and other nucleic acids. Biotin-5-deoxycytidine-5'-triphosphate, lithium salt - 1 mM aqueous solution is an active ingredient in many research laboratories.</p>Formula:C22H35N6O15P3SPurity:Min. 95%Molecular weight:748.53 g/moldNaM
CAS:<p>dNaM is a metabolite of DNA that has been shown to be a potential biomarker for metabolic disorders and autoimmune diseases. dNaM levels are elevated in the blood of pregnant women, which may serve as a marker for preeclampsia. Elevated levels have also been observed in patients with type 2 diabetes, obesity, and cancer. Methylation plays an important role in dNaM metabolism. The enzyme DNA methyltransferase (DNMT) catalyzes the transfer of methyl groups from S-adenosyl methionine to cytosine residues on the DNA molecule. DNMT activity is increased by high body mass index (BMI), low vitamin B12 levels, and HIV infection. This enzyme is also inhibited by valproic acid and deprenyl, which may affect dNaM methylation status.</p>Formula:C16H18O4Purity:Min. 95%Molecular weight:274.31 g/mol2-Amino-4-(4-bromophenyl)pyrimidine
CAS:<p>2-Amino-4-(4-bromophenyl)pyrimidine is a phosphoramidite, modified nucleoside. It is an antiviral and anticancer agent that inhibits DNA synthesis. 2-Amino-4-(4-bromophenyl)pyrimidine is a novel nucleotide analog with the ability to inhibit replication of RNA and DNA in vitro. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), cytomegalovirus (CMV), and HIV in cell culture. Furthermore, this phosphoramidite has been shown to have no detectable toxicity in mice at doses up to 2000 mg/kg.</p>Formula:C10H8BrN3Purity:Min. 95%Molecular weight:250.09 g/mol2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine
CAS:<p>2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine is a modified nucleoside that inhibits viral DNA and RNA synthesis. It has antiviral properties against influenza, herpes simplex virus type 1, hepatitis B virus, and human immunodeficiency virus type 1. 2-Amino-8-bromo-9-(b-D-ribofuranosyl)purine has been shown to be effective in the treatment of cancers such as leukemia, lymphoma, and breast cancer. This drug is a novel nucleoside analogue that is used for cancer chemotherapy. 2-Amino 8 bromo 9 (b D ribofuranosyl) purine is not active against bacteria or fungi.</p>Formula:C10H12BrN5O4Purity:Min. 95%Molecular weight:346.14 g/mol4-Aminopyrimidine-5-carboxylic acid
CAS:<p>4-Aminopyrimidine-5-carboxylic acid is an aminopyrimidone that has been synthesized to be used as a new class of antihypertensive agents. It has dose-dependent blood pressure lowering effects, which are likely due to its ability to block angiotensin receptors. 4-Aminopyrimidine-5-carboxylic acid also has antibacterial and antifungal properties. This compound is metabolized in vivo into the pharmacologically active amine 6-aminonicotinamide and excreted in the urine. In vitro studies have shown that 4-aminopyrimidine-5 carboxylic acid inhibits the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes required for cell division.</p>Formula:C5H5N3O2Purity:Min. 95%Molecular weight:139.11 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone
CAS:<p>4-Amino-2,6-dimethyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone is a fluorescent probe that can be used to monitor nucleic acid synthesis. It is an analog of adenosine and interacts with the enzyme RNA polymerase in a process that is mediated by the adenosine receptor, which leads to termination of transcription. This compound has been shown to yield high fluorescence yields at room temperature and has minimal interaction with other monomers or dimers. 4-Amino-2,6-dimethyl-8-(2'-deoxy-b-D-ribofuranosyl)-7-pteridone can be used as a probe for monitoring DNA synthesis in vitro and in vivo.</p>Formula:C13H17N5O4Purity:Min. 95%Molecular weight:307.31 g/mol3’-O-(2-Methoxyethyl)guanosine
CAS:<p>3’-O-(2-Methoxyethyl)guanosine is a nucleoside analogue of guanosine. It is a modified, deoxyribonucleoside that is synthesized from 2-methoxyethanol and 1,2-dihydroxybenzene. 3’-O-(2-Methoxyethyl)guanosine has antiviral, anticancer, and DNA synthesis inhibitory activities. This nucleoside analogue increases the intracellular concentration of guanosine by inhibiting its degradation. 3’-O-(2-Methoxyethyl)guanosine has been used as an antiviral agent in the treatment of influenza A virus infection in humans and animals.</p>Purity:Min. 95%4-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS:<p>4-Chloro-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a novel anticancer compound that inhibits the synthesis of DNA, RNA and protein. It is a phosphoramidite monophosphate that can be used in the synthesis of oligonucleotides and DNA. 4CHP is effective against Herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). 4CHP also has antiviral activity against influenza A virus.</p>Formula:C12H14ClN3O4Purity:Min. 95%Molecular weight:299.71 g/molL-5-methyluridine
CAS:<p>L-5-methyluridine is a nucleoside that is used as a building block in the synthesis of oligonucleotides. It contains one ribose sugar and one deoxyribose sugar, linked to the base adenine by a phosphate group. L-5-methyluridine can be synthesized from 5-chloro-2'-deoxyadenosine, hypoxanthine, and ammonium chloride. The synthesis starts with condensation reactions between the two sugar molecules to form an intermediate called a nucleoside. This is followed by alkylation of the base and then oxidation of the sugar group to form anomeric esters. The last step involves hydrolysis of the acyloxy ester, which yields L-5-methyluridine after acidification.</p>Formula:C10H14N2OPurity:Min. 95%Molecular weight:178.23 g/molSPACER-C 12 CEP
CAS:<p>Please enquire for more information about SPACER-C 12 CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C42H61N2O5PPurity:Min. 95%Molecular weight:704.9 g/mol3-[2'-Deoxy-5'-O-DMT-b-D-ribofuranosyl]pyrido[2,3-d]pyrimidine-2,7(8H)-dione 3'-CE phosphoramidite
CAS:<p>3-[2'-Deoxy-5'-O-DMT-b-D-ribofuranosyl]pyrido[2,3-d]pyrimidine-2,7(8H)-dione 3'-CE phosphoramidite is a synthetic compound that is a member of the class of brassinosteroids. It has been shown to activate the transcription factor NF-Y in vitro and in vivo. Brassinosteroids have been shown to have regulatory effects on plant tissue development, including normalization of cell growth, and are involved in the activation of cellulase activity. They also have been shown to increase the resistance of plants to environmental stresses such as drought.</p>Formula:C42H48N5O8PPurity:Min. 95%Molecular weight:781.83 g/mol2',3'-Dideoxyguanosine-5'-triphosphate
CAS:<p>2',3'-Dideoxyguanosine-5'-triphosphate (ddGTP) is a nucleotide analog that inhibits the formation of DNA and RNA, which are important for protein synthesis. It is used in clinical studies to assess prognosis and to evaluate drug elimination. ddGTP has been shown to inhibit mitochondrial membrane potential, decrease mitochondrial superoxide, and inhibit cancer growth. It also prevents allergic reactions by preventing the release of histamine. The use of probiotic bacteria containing ddGTP may help in the treatment of inflammatory bowel disease.</p>Formula:C10H14N5O6PPurity:Min. 95%Molecular weight:331.22 g/mol5-Fluoro-2',3'-O-isopropylidenecytidine
CAS:<p>5-Fluoro-2',3'-O-isopropylidenecytidine is a modified nucleoside that has antiviral and anticancer properties. It is a diphosphate of cytidine, with a fluorine atom in the 2'-position and an isopropyl group in the 3'-position. 5-Fluoro-2',3'-O-isopropylidenecytidine is synthesized by reacting 5-fluorocytidine with isopropylamine. This novel compound has been shown to have high quality, high purity, and improved biological activity as compared to other nucleosides.</p>Formula:C12H16FN3O5Purity:Min. 95%Molecular weight:301.27 g/mol5’-Deoxy-5’-iodouridine
CAS:<p>5’-Deoxy-5’-iodouridine (5DIU) is an antiviral agent that inhibits the synthesis of DNA by interfering with the enzyme thymidine kinase, which converts thymine to uracil. It is used in the treatment of cutaneous herpes simplex virus infections. 5DIU has been shown to inhibit viral replication and yield in vitro. The drug showed no significant toxicity in mice, rats, or hamsters. In addition, it has been observed that 5DIU does not interfere with human cell growth, which may be due to its lack of activity against a wide range of human enzymes.</p>Purity:Min. 95%2-Amino-4-(thien-2-yl)pyrimidine
CAS:<p>2-Amino-4-(thien-2-yl)pyrimidine is a bioavailable, water soluble antiallergy drug. 2-Amino-4-(thien-2-yl)pyrimidine has been shown to be effective against allergic asthma and other allergic diseases. It is thought to work by blocking the release of histamine from mast cells, thereby preventing the production of inflammatory prostaglandins and leukotrienes. This drug also blocks the response to allergies by inhibiting the release of IgE antibodies that bind to allergens. The therapeutic effect of 2-amino-4-(thien-2-yl)pyrimidine is repeatable and it does not cause any adverse effects on potassium or carbonate metabolism.</p>Formula:C8H7N3SPurity:Min. 95%Molecular weight:177.23 g/mol8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine
CAS:<p>8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine (8-APdG) is a mutagen that induces genotoxic effects and mutations in mammalian cells. It has been shown to react with DNA to form covalent complexes and induce point mutations or transversions. 8-APdG has been found in the environment as a result of environmental pollution by polycyclic aromatic hydrocarbons and tobacco smoke. 8-APdG also induces genetic damage in human lymphoblastoid cells in vitro, including mutations at the HPRT locus.</p>Formula:C23H23N9O4Purity:Min. 95%Molecular weight:489.49 g/molDecanoyl coenzyme A, free acid
CAS:<p>Decanoyl CoA, free acid, is a substrate of the enzyme fatty acid synthetase. This enzyme catalyzes the formation of long-chain fatty acids from acetyl-CoA and malonyl-CoA. The product decanoyl-CoA is then used in other metabolic pathways to synthesize acyl chains for phospholipids, triglycerides, and cholesterol. Decanoyl CoA has been shown to inhibit carnitine acyltransferase activity in rat liver microsomes. It also inhibits mitochondrial beta-oxidation by competing with carnitine at the level of the carnitine acyltransferase reaction. The expression plasmid pET21a was used to express the decanoyl CoA synthetase protein in Escherichia coli cells grown in LB medium with aminotransferase activity as a measure of decanoyl CoA synthetase activity. Decanoyl CoA</p>Formula:C31H54N7O17P3SPurity:Min. 95%Molecular weight:921.78 g/mol2',3'-Dideoxyadenosine-5'-triphosphate lithium salt
CAS:<p>2',3'-Dideoxyadenosine-5'-triphosphate lithium salt is a nucleoside for use in research applications</p>Formula:C10H16N5O11P3·xLiPurity:Min. 95%Color and Shape:Clear liquid.Molecular weight:475.18 g/molT-705RTP sodium
CAS:<p>T-705RTP sodium is a novel, modified diphosphate nucleotide that activates the formation of DNA and RNA. It is used as an antiviral and anticancer agent. T-705RTP sodium has been shown to be more potent than adenosine in inhibiting viral replication and has cytotoxic effects on cancer cells. The chemical formula for T-705RTP sodium is C6H14N5O7P.</p>Formula:C10H15FN3O15P3·xNaPurity:Min. 95%2'-Azido-2'-deoxyuridine-5'-triphosphate
CAS:<p>2'-Azido-2'-deoxyuridine-5'-triphosphate is a nucleotide analog that is inactive in the presence of an intact receptor. It is an allosteric inhibitor of many DNA polymerases and causes cell growth inhibition. 2'-Azido-2'-deoxyuridine-5'-triphosphate binds to the phosphate group of ATP and inhibits protein synthesis. In particular, it inhibits the polymerase activity of herpes simplex virus type 1 by binding to the active site of the enzyme, thereby preventing viral replication. 2'-Azido-2'-deoxyuridine-5'-triphosphate also binds to cytosolic Ca2+ and activates Ca2+ signaling pathways, leading to cell death.</p>Formula:C9H14N5O14P3Purity:Min. 95%Molecular weight:509.15 g/mol9-(b-D-Arabinofuranosyl)adenine 5'-triphosphate triethyammonium salt
<p>9-(B-D-arabinofuranosyl)adenine 5'-triphosphate triethyammonium salt is a nucleoside analog that inhibits viral replication by inhibiting the DNA polymerase enzyme. It has been shown to be safe and well tolerated in healthy volunteers and patients with cancer, including those with advanced solid tumors. 9-(B-D-arabinofuranosyl)adenine 5'-triphosphate triethyammonium salt is an antiviral agent that has been shown to be active against HIV, herpes simplex virus type 1, herpes simplex virus type 2, cytomegalovirus, and varicella zoster virus. This compound also has anticancer properties and has been shown to inhibit tumor cell proliferation in vitro.</p>Purity:Min. 95%Cholest-5-en-3-ol, 3-(6-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)hexyl)carbemate
CAS:<p>Cholest-5-en-3-ol, 3-(6-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)hexyl)carbemate, is a novel nucleotide analog that has antiviral and anticancer properties. It is synthesized by the reaction of 2,4,6-trihydroxyacetophenone with 6-(chlorohexyl)-1,3-bis(2-(cyanoethoxy)phosphinooxy)hexane in the presence of tetrakis(triphenylphosphine), palladium chloride, and potassium carbonate. Cholest-5-en-3-ol, 3-(6((2-(cyanoethoxy)(diisopropylamino))(phosphino)oxy)(hexyl))carbamate may be used as a monophosphate or phosphoramidite to make DNA or RNA. This compound has been shown to</p>Purity:Min. 95%2-Cyanoadenosine
CAS:<p>2-Cyanoadenosine is a derivative of adenosine. It is an inhibitor of the enzyme adenosine deaminase, which converts adenosine to inosine. 2-Cyanoadenosine prevents the conversion of ATP to AMP and may be useful for treating neurological disorders. 2-Cyanoadenosine has been shown to have cardiovascular effects, such as increasing the force of contraction and relaxation in isolated rat hearts.</p>Purity:Min. 95%2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine
CAS:<p>2,6-Diamino-9-(2'-amino-2'-deoxy-b-D-ribofuranosyl)purine (dAraMP) is a novel nucleoside analogue that was synthesized and characterized. It has been shown to inhibit the growth of cancer cells in vitro. dAraMP is a monophosphate analogue of 2,6-diamino-9-(2'-deoxy-b-D-ribofuranosyl)purine (dAraP). The modified phosphoramidite approach used in its synthesis yielded high purity and yields. This product is also available as a diphosphate analogue of 2,6 diamino 9-(2'-amino 2'-deoxy b D ribofuranosyl) purine (dAMP). The diphosphate form of this product has been shown to be an activator for DNA polymerase.</p>Formula:C10H15N7O3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:281.28 g/mola,b-Methyleneguanosine 5'-diphosphate sodium salt
CAS:<p>a,b-Methyleneguanosine 5'-diphosphate sodium salt is a chemical species that binds to the influenza virus neuraminidase. The drug binding site on the influenza virus neuraminidase has been identified in high resolution by NMR and X-ray crystallography. This drug is able to inhibit the release of infectious particles and prevent infection by the influenza virus, which is an important biological weapon in bioterrorism. The compound is not active against other viruses such as HIV and herpes simplex virus type 1. In addition, this chemical species also inhibits the activity of geniculate nucleus neurons and may be effective for treatment of chronic pain caused by nerve injury.</p>Formula:C11H17N5O10P2·xNaPurity:Min. 95%Molecular weight:441.23 g/mol[U-13C10, U-15N2]-Labelled thymidine
<p>Thymidine is a nucleoside that is a component of DNA and RNA. It is also the precursor for thymine, the DNA base in which the thymine ring is derived from. Thymidine has been shown to be an activator of DNA synthesis, as well as being anticancer and antiviral.</p>Purity:Min. 95%N-Benzoyl- 5'- O- DMT- 2'- O-[( triisopropylsilyl oxy)methyl]-adenosine 3'- CE phosphoramidite
CAS:<p>N-Benzoyl- 5'-O-DMT-2'-O-[(triisopropylsilyloxy)methyl]-adenosine 3'-Ce phosphoramidite (Bz-5'-O-DMT-2'-O-[(triisopropylsilyloxy)methyl]-Ado-3'-Ce Phosphoramidite) is a novel nucleoside phosphoramidite. It is an analogue of the natural nucleoside adenosine. This compound has been shown to be an antiviral and anticancer agent in vitro. Bz-5'-O-DMT-2'-O-[(triisopropylsilyloxy)methyl]-Ado-3'-Ce Phosphoramidite can also act as a DNA or RNA activator, which leads to increased levels of transcription, translation, and replication by increasing the number of ribonucleotide tri</p>Purity:Min. 95%3'-Deoxy-N2-DMF-5'-O-DMT-guanosine
CAS:<p>3'-Deoxy-N2-DMF-5'-O-DMT-guanosine is a modified nucleoside that is phosphorylated to the 3'-deoxyribonucleotide form. It has antiviral and anticancer activities, as well as being an activator of DNA and RNA synthesis. This compound has been shown to inhibit the growth of several cancer cell lines in vitro and in vivo. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine is also effective against herpes simplex virus type 1 (HSV1) and HSV type 2 in cell culture, although it does not have any effect on HSV type 1 replication in animal models.</p>Formula:C34H36N6O6Purity:Min. 95%Molecular weight:624.69 g/mol2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate
CAS:<p>2-Bromo-2-deoxy-5-methyluridine-3,5-diacetate is a novel synthetic nucleoside analogue. It has been shown to inhibit the proliferation of cancer cells and have antiviral activity. It is phosphorylated by kinase enzymes to form 2'-bromo-2'-deoxyuridine monophosphate (BrDUMP). This compound also inhibits DNA replication, RNA transcription, and protein synthesis.</p>Purity:Min. 95%2'-Deoxy-5'-O-DMT-5-iodocytidine
<p>2'-Deoxy-5'-O-DMT-5-iodocytidine is a modified nucleoside that has antiviral and anticancer properties. 2'-deoxy-5'-O-DMT-5-iodocytidine is able to activate the DNA polymerase, ribonucleotide reductase, and deoxyribonucleotide reductase enzymes. This product can be used as a monophosphate or diphosphate. The CAS number for this compound is 141475-07-4.</p>Purity:Min. 95%5-Fluoro-6-iodouridine
CAS:<p>5-Fluoro-6-iodouridine is a nucleoside that is used as the starting material for synthesizing fluorinated pyrimidine derivatives, which are used in cancer treatment. 5-Fluoro-6-iodouridine is an activator of ribonucleotide reductase and can be used to inhibit the growth of tumor cells. 5-Fluoro-6-iodouridine has been shown to inhibit the proliferation of human leukemia cells in culture, with cytotoxicity that was comparable to that of 5-fluorouracil.</p>Formula:C9H10FIN2O6Purity:Min. 95%Molecular weight:388.09 g/molUridine-2-13C
CAS:<p>Uridine-2-13C is a modified nucleoside that is used as an anticancer agent. It is phosphorylated to uridine-2-13C diphosphate and can be used in DNA synthesis and as a radiolabel.</p>Formula:C9H12N2O6Purity:Min. 95%Molecular weight:245.19 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-5-methyluridine is a novel nucleoside that is activated with anhydrous ammonia and then converted to the corresponding 5'-O-DMT derivative. The 2'-O-tert-butyldimethylsilyl group protects the 5'-position of the sugar moiety from attack by phosphodiesterases, allowing for its use as a substrate in DNA synthesis. The ribose moiety is also modified at the 2' position, which prevents the formation of 3',5'-cyclic monophosphate (cMP) during dephosphorylation and thereby inhibits viral replication. This nucleotide analog has been shown to be active against HIV, hepatitis B virus, and influenza A virus.</p>Purity:Min. 95%6-Chloropurine riboside 5'-monophosphate disodium salt
CAS:<p>6-Chloropurine riboside 5'-monophosphate disodium salt is a synthetic nucleoside that is used as an antiviral and anticancer agent. It is a DNA precursor that can be incorporated into DNA by the enzyme thymidylate synthase to form thymine and diphosphate. 6-Chloropurine riboside 5'-monophosphate disodium salt has been shown to inhibit the replication of some viruses, such as HIV, and also inhibits tumor growth in experimental models.</p>Formula:C10H10ClN4Na2O7PH2OPurity:Min. 95%Molecular weight:428.63 g/mol2'-Deoxy-5'-O-DMT-N2-iBu-guanosine-3'-succinyl CPG 500 Å
<p>2'-Deoxy-5'-O-DMT-N2-iBu-guanosine-3'-succinyl CPG 500 Å is an anticancer agent that is used in the synthesis of DNA and RNA. It can be used as a monophosphate or diphosphate, and has been shown to inhibit cancer cells. 2'-Deoxy-5'-O-DMT-N2-iBu-guanosine-3'-succinyl CPG 500 Å is modified to have a long half life in the body. This chemical has been synthesized with high purity and quality, making it suitable for research purposes.</p>Purity:Min. 95%N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-cytidine
CAS:<p>N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-cytidine is a synthetic nucleoside that is used as an antiviral. It has been shown to be effective against HIV and HSV. N-Benzoyl-2'-O-[(methylthio)methyl]-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-cytidine prevents the synthesis of DNA by inhibiting the enzyme ribonucleotide reductase. It also inhibits the production of deoxyribonucleotides and DNA by binding to the active site of the enzyme DNA polymerase.</p>Formula:C30H47N3O7SSi2Purity:Min. 95%Molecular weight:649.95 g/mol
