Nucleosides
Nucleosides are fundamental building blocks of nucleic acids, composed of a nitrogenous base attached to a sugar molecule. In this section, you can find a wide variety of nucleosides essential for research in molecular biology, biochemistry, and pharmacology. These compounds play crucial roles in the synthesis of DNA and RNA, and are also vital in various metabolic processes. Nucleosides are used in studying genetic material, developing antiviral and anticancer therapies, and understanding cellular mechanisms. At CymitQuimica, we provide high-quality nucleosides to support your research and development needs, ensuring purity and reliability for your experimental applications.
Found 3569 products of "Nucleosides"
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
8-Azidocyclic adenosine diphosphate ribose
CAS:8-Azidocyclic adenosine diphosphate ribose (8AADPR) is a molecule that is synthesized from ATP and ribose. It has been shown to inhibit the endoplasmic reticulum Ca2+-ATPase, which transports calcium ions out of the cell, leading to increased concentrations of calcium ions in the cytosol. 8AADPR also inhibits mitochondrial ATPase, which leads to an accumulation of ADP-ribose within mitochondria. This accumulation leads to the inhibition of protein synthesis within mitochondria and an activation of ryanodine receptors. There are no known adverse effects associated with 8AADPR at this time, but it should be used with caution due to its potential effects on cardiac function.Formula:C15H20N8O13P2Purity:Min. 95%Molecular weight:582.31 g/mol2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It is a modified nucleoside with a purine base. It has been shown to be effective against certain cancer cells in vitro and in vivo. This drug also has antiviral properties, which may be due to its ability to inhibit DNA synthesis through the inhibition of viral RNA replication. 2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is resistant to phosphorylation by kinase enzymes and it can be used as a precursor for the preparation of other nucleosides.Formula:C11H16N6O4Purity:Min. 95%Color and Shape:White to off-white solid.Molecular weight:296.29 g/mol4-Phenylpyrimidine-2-thiol
CAS:4-Phenylpyrimidine-2-thiol is a chemical compound that belongs to the group of elemental compounds. It has a density of 1.5 g/mL, a melting point of > 200 °C, and a boiling point of > 300 °C. 4-Phenylpyrimidine-2-thiol has been shown to exist as chains with assembled chains in the crystalline state. The crystals are composed of two molecules stacked on top of each other in an antiparallel orientation. The crystal structure was solved through x-ray crystallography and single-crystal x-ray diffraction. 4-Phenylpyrimidine-2-thiol is dimeric in solution and polymerizes in the solid state to form polymers with chains consisting of four phenylpyrimidine units. This compound has an elemental analysis consisting mainly of carbon and hydrogen, with small amounts of sulfur and nitrogen present.Formula:C10H8N2SPurity:Min. 95%Molecular weight:188.25 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytosine is an antiviral compound that inhibits the synthesis of viral RNA. This nucleoside analog is a monophosphate and diphosphate inhibitor of ribonucleotide reductase, which is required for DNA and RNA synthesis. N4-Benzoylcytosine has also been shown to be cytotoxic against tumor cells in vitro and in vivo, making it a potential anticancer drug. It was synthesized as part of a novel series of compounds that have been shown to inhibit the growth of bacterial cultures, including Mycobacterium tuberculosis.Formula:C37H34FN3O7Purity:Min. 95%Molecular weight:651.7 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
CAS:3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a nucleoside that is modified with a tert-butyldimethylsilyl group at the 3' position. It is used as an activator for synthesizing oligonucleotides, ribonucleosides, and phosphoramidites. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine has antiviral and anticancer properties. This product can be used in research applications such as the synthesis of novel DNA and RNA molecules, as well as for diagnostic purposes such as detecting viral infections.Formula:C36H44N2O8SiPurity:Min. 95%Molecular weight:660.83 g/molN6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine
N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has the potential to be a therapeutic agent for cancer and antiviral therapy. It is an analog of adenosine that inhibits viral replication by inhibiting the viral enzyme RNA-dependent DNA polymerase. N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine also inhibits tumor growth by inducing apoptosis. The compound has been shown to inhibit human leukemia cells in vitro, as well as mouse leukemia cells in vivo. This novel nucleoside is synthesized through a two step process starting with 5'-chloroadenosine and converting it to 5'-chloroinosidine with potassium cyanide, followed by deoxygenation at the 6 position with benzoyl chloride and sodium hydroxide.Purity:Min. 95%2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine
CAS:2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an antiviral nucleoside. It is a novel nucleotide analog that inhibits human immunodeficiency virus (HIV). The cytidine monophosphate moiety of 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine has been modified with the substitution of the acetyl group at the 2' position with a deoxyribose group, and the 5' fluoro group with a 5'-deoxyfluro group. This modification prevents phosphodiesterases from hydrolyzing it to its monophosphate form, which leads to higher antiviral activity. 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro -Formula:C19H26FN3O8Purity:Min. 95%Molecular weight:443.42 g/mol5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å
5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å is an Activator that is a monophosphate and synthesized through the modification of nucleosides. It has novel anticancer properties and is a high quality, high purity, and modified nucleotide. The 5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å has been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) in human cells. It also has anticancer effects on human leukemia cells by inhibiting the growth of cancer cells.Purity:Min. 95%5’-O-DMT cET-N4-benzoylcytidine 3’-OCE amdite
CAS:The LNA locks the ribose ring in a fixed configurationFormula:C49H56N5O9PMolecular weight:889.97 g/mol5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carbonitrile
CAS:5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carbonitrile is a novel nucleoside analogue that inhibits the viral enzyme ribonucleotide reductase. It has antiviral activity against the herpes viruses, cytomegalovirus, and Epstein Barr virus. 5AADC has also been shown to inhibit DNA synthesis in tumor cells. This compound is currently undergoing clinical trials as an anticancer agent.Formula:C15H18N4O7Purity:Min. 95%Molecular weight:366.33 g/mol3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine
3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine is a novel nucleoside that has been described as an activator of diphosphate. It is a modified deoxyribonucleoside, with the amino group in the ribose moiety replaced by an azido group. This nucleotide inhibits viral and cellular DNA synthesis by blocking DNA polymerase. 3'-Azido-N4-benzoyl-5'-O-trityl-2',3'-dideoxyadenosine can also be used for anticancer purposes, where it has been shown to inhibit cancer cell growth.Formula:C36H30N8O3Purity:Min. 95%Molecular weight:622.68 g/mol7’-Hydroxy-N-Trityl-morpholino guanine
CAS:Please enquire for more information about 7’-Hydroxy-N-Trityl-morpholino guanine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C29H28N6O3Molecular weight:508.57 g/mol2,6-Dichloro-7-methylpurine
CAS:2,6-Dichloro-7-methylpurine (2,6-DCMP) is a chlorinated purine analog that has anticancer activity. It is an ATP competitive inhibitor that inhibits protein synthesis by competitively binding to the alpha subunit of the ribosome. 2,6-DCMP has been shown to have strong antiviral activity against human immunodeficiency virus and cytotoxic effects on human adenocarcinoma cells in vitro. The IC50 values for this compound are 50 nM against HIV and 5 μM against human adenocarcinoma cells.Formula:C6H4Cl2N4Purity:Min. 95%Molecular weight:203.03 g/mol5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å
5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å is a nucleoside, modified with succinyldiimidazopropylcarbodiimide. It is an activator of phosphoramidites and is used in the synthesis of DNA and RNA. 5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å has shown anticancer and antiviral properties in vitro.Purity:Min. 95%Guanosine-5'-monophosphate triethylammonium salt
CAS:Guanosine-5'-monophosphate triethylammonium salt is a synthetic nucleoside that is an activator of DNA. It is used in antiviral and anticancer treatments, as well as in the synthesis of deoxyribonucleosides. This product has been shown to have high purity and high quality.Formula:C10H14N5O8P•C6H15NPurity:Min. 95%Molecular weight:464.41 g/molN6-Cyclopentyladenosine-5'-O-monophosphate
CAS:N6-Cyclopentyladenosine-5'-O-monophosphate is a nucleoside that is a substrate for RNA polymerase and is involved in the regulation of transcription. It also has been shown to be localized in the nucleus, cytoplasm, and cell membrane. N6-Cyclopentyladenosine-5'-O-monophosphate is used in diagnosis as an immunochemical reagent for the detection of matrix metalloproteinases (MMPs) and it can be used to measure MMP-9 activity. The monoclonal antibody (mAb) against this nucleoside can be used to detect N6-Cyclopentyladenosine-5'-O-monophosphate in biological samples such as human serum or cell culture.Formula:C15H22N5O7PPurity:Min. 95%Molecular weight:415.34 g/mol6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine
CAS:6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine is a novel antiviral and anticancer agent. It is an analog of adenosine that inhibits viral replication by inhibiting DNA synthesis. 6CePP2A is an activator of nucleoside deoxyribonucleotidyltransferase, which converts dATP to dTTP.Formula:C10H12ClN5O3Purity:Min. 95%Molecular weight:285.69 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine
N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine is a novel nucleoside analog that is activated by ribonucleotide reductase. This compound inhibits the synthesis of DNA and RNA in cells, which leads to the inhibition of cellular proliferation. N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-trifluoroacetamidocytidine has been shown to be effective against cancer cells, as well as antiviral and antiretroviral activity. It is also active against drug resistant strains of HIV.Formula:C39H35F3N4O8Purity:Min. 95%Molecular weight:744.71 g/mol2-(sec-Butylthio)pyrimidine-5-carbaldehyde
CAS:2-(sec-Butylthio)pyrimidine-5-carbaldehyde is a molecule that inhibits cell growth and angiogenesis. It was found to inhibit the phosphorylation of specific proteins, leading to the inhibition of cell growth and angiogenesis. This compound has been shown to be effective against prostate cancer cells in vitro and in vivo, as well as in a mouse model for breast cancer. In this model, the drug inhibited tumor growth without any apparent toxicity to normal tissues. 2-(sec-Butylthio)pyrimidine-5-carbaldehyde has been tested as a potential antiangiogenic agent in mice, with results showing no adverse effects on animals.Formula:C9H12N2OSPurity:Min. 95%Molecular weight:196.27 g/molN4-Benzoyl-5’-O-DMT-morpholinocytidine-N’-CE phosphoramidite
CAS:Please enquire for more information about N4-Benzoyl-5’-O-DMT-morpholinocytidine-N’-CE phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this pageFormula:C46H53N6O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:832.92 g/mol4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine
CAS:4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine is a monophosphate of the nucleoside 5FU. It is an antiviral and anticancer agent that inhibits viral DNA synthesis by competitively inhibiting the activity of thymidylate synthase, which converts dUMP to dTMP. 4',5'-Didehydro-2',5'-dideoxy-2'-fluorouridine also induces apoptosis in neoplastic cells. This compound has high purity and quality, and can be used as a phosphoramidite for the synthesis of modified oligonucleotides.Formula:C10H10FNO4Purity:Min. 95%Molecular weight:227.19 g/molN4-Ethyl-2'-deoxycytidine
CAS:N4-Ethyl-2'-deoxycytidine is a novel nucleoside analog that inhibits the activity of DNA polymerase. It is used as an anticancer, antiviral and antiretroviral agent. N4-Ethyl-2'-deoxycytidine has been shown to be active against herpes simplex virus type 1 (HSV-1), HSV-2, cytomegalovirus (CMV), human immunodeficiency virus type 1 (HIV-1) and HIV-2 in vitro. This drug also has antiangiogenic properties due to its ability to inhibit the synthesis of vascular endothelial growth factor A. N4-Ethyl-2'-deoxycytidine is a modified nucleoside that can be phosphorylated by cellular enzymes, which activates it by converting it into a monophosphate or diphosphate form. This drug inhibits the production of RNA from DNA and also prevents proteinFormula:C11H17N3O4Purity:Min. 95%Molecular weight:255.27 g/molN6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt
CAS:N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt is a novel antiviral and anticancer agent that is a synthetic nucleoside analogue. It has been shown to be effective at inhibiting the growth of human cancer cells in vitro and in vivo. N6-Monobutyryl-2'-deoxyadenosine 3',5'-cyclic monophosphate sodium salt binds to viral RNA, resulting in inhibition of protein synthesis and cell death.Formula:C14H18N5O6P·NaPurity:Min. 95%Molecular weight:406.29 g/mol2-(Methylthio)-4-(P-Tolylamino)Pyrimidine-5-Carboxylic Acid
CAS:2-(Methylthio)-4-(P-tolylamino)pyrimidine-5-carboxylic acid is an anticancer drug that is a novel, modified nucleoside. It has been shown to be active as a monophosphate and diphosphate in vitro. 2-(Methylthio)-4-(P-tolylamino)pyrimidine-5-carboxylic acid has also been shown to have antiviral activity against HIV and herpes simplex virus type 1 (HSV1).Formula:C13H13N3O2SPurity:Min. 95%Molecular weight:275.33 g/mol2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite is a novel modified nucleoside that is synthesized by the reaction of 2'-deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl] uridine with bis(2,4,6-trimethylbenzoyl)phosphine and then with tetrazole. This product inhibits the synthesis of viral RNA and DNA and has been shown to be effective against cancer cells in vitro.Formula:C44H49F3N5O9PPurity:Min. 95%Molecular weight:879.86 g/mol8-Bromoguanosine-5'-triphosphate sodium salt - 10 mM aqueous solution
CAS:8-Bromoguanosine-5'-triphosphate sodium salt is a nucleotide analog that inhibits the enzyme ribonucleotide reductase. This drug inhibits bacterial growth by interfering with protein synthesis and cell division. It binds to the purine riboswitch, which is an allosteric regulatory binding site on the ribosome, inactivating it. 8-Bromoguanosine-5'-triphosphate sodium salt also binds to the active site of bacterial RNA polymerase and inhibits DNA synthesis. The activity of this drug has been shown using a bacteriophage system in which the enzyme protein synthesis was inhibited by 8-bromoguanosine-5'-triphosphate sodium salt.Formula:C10H15N5O14P3Br·xNaPurity:Min. 95%Molecular weight:602.08 g/mol5'-O-DMT-2,3'-anhydrothymidine
CAS:5'-O-DMT-2,3'-anhydrothymidine is a solvent that is used for labeling nucleic acids. It can be used in positron emission tomography (PET) imaging as a diagnostic tool for cancer and other diseases. 5'-O-DMT-2,3'-anhydrothymidine is also used to carry the radioactive isotope fluorodeoxyglucose (FDG) in positron emission tomography (PET). The FDG is labeled with the PET tracer and then injected into the patient's body. This allows for whole-body visualization of glucose metabolism and tumor cell uptake.Formula:C31H30N2O6Purity:Min. 95%Molecular weight:528.61 g/mol2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine
2,6-Dichloro-9-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro-a-D-arabinofuranosyl)purine is a nucleoside that is used in the synthesis of antiviral drugs. It is a modified monophosphate with a 3',5'-di-O-benzoyl group and 2'-deoxyribose. This substance can be prepared from the corresponding 2,6-dichloropurine by reaction with chloroacetaldehyde diethyl acetal. 2,6 Dichloro 9-(3',5'-di-O-benzoyl) purine has been shown to have anticancer activity against various human cancer cell lines in vitro and in vivo.Purity:Min. 95%1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol
1,5-Anhydro-2,3-dideoxy-2-(N2-isobutyrylguanidin-1-yl)-D-glucitol is a novel, activator ribonucleosides deoxyribonucleosides diphosphate phosphoramidites modified anticancer antiviral monophosphate nucleosides synthetic high purity CAS No. It has been shown to have anticancer and antiviral properties. This compound also inhibits the replication of HIV in vitro.Formula:C15H21N5O5Purity:Min. 95%Molecular weight:351.37 g/mol2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde
CAS:2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde is an antiviral and anticancer phosphoramidite. It is a novel monophosphate nucleoside analogue that inhibits DNA synthesis by inhibiting the activity of ribonucleotide reductase. 2-(1-Piperidinyl)-5-pyrimidinecarbaldehyde has been shown to be effective against influenza virus, HIV, Herpes Simplex Virus, and human leukemia cells. This compound is not active against bacteria or fungi.Formula:C10H13N3OPurity:Min. 95%Molecular weight:191.23 g/mol3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine
3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine (Zidovudine) is a nucleoside analog that inhibits the replication of human immunodeficiency virus type 1. It is phosphorylated by cellular enzymes to form the active triphosphate form, which incorporates into viral DNA and causes chain termination. Zidovudine has been used in the treatment of HIV infection and AIDS. This drug also has antiviral activity against other retroviruses such as HIV type 2 and measles virus, as well as some DNA viruses, such as herpes simplex type 1. Zidovudine may be useful for the treatment of cancer, particularly Kaposi's sarcoma.Purity:Min. 95%N2-Isobutyryl-5’-O-DMT-morpholinoguanosine-N’-CE phosphoramidite
CAS:A morpholino amidite
Formula:C44H55N8O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:838.93 g/molN6-Benzoyl-5’-O-DMT-morpholinoadenosine-N’-CE phosphoramidite
CAS:A morpholino amiditeFormula:C47H53N8O6PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:856.95 g/mol3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine
CAS:3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a novel antiviral agent that has been synthesized as a high quality, high purity monophosphate. It is a modified nucleoside that is used to synthesize phosphoramidites. It has antiviral activity against herpes simplex virus type 1 and 2, and cytomegalovirus. 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is also an inhibitor of the DNA polymerase enzyme and inhibits the synthesis of viral DNA in infected cells. This drug can be used for the treatment of infections caused by these viruses.Formula:C13H14BrFN2O7Purity:Min. 95%Molecular weight:409.16 g/mol2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde
CAS:2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a Ribonucleside, Deoxyribonucleoside, Activator, Antiviral, Synthetic and Modified DNA Nucleoside. It has been shown to inhibit viral replication in vitro by interfering with the formation of the viral diphosphate. 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a ribonucleotide that is synthesized from commercially available starting materials. This compound has shown to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of AIDS. 2-Methylsulfanyl-4-phenylamino pyrimidine 5 carbaldehyde (2MSAP) was found to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment ofFormula:C12H11N3OSPurity:Min. 95%Molecular weight:245.3 g/mol5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine
CAS:5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine is a nucleoside analog that is an activator of DNA polymerase. It has been shown to have anticancer activity in vitro and in vivo. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine was found to inhibit the proliferation of leukemia cells, human colon cancer cells, and human prostate cancer cells. This compound also inhibits viral replication by affecting the synthesis of viral DNA and RNA. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine may be used as a research tool for studying the mechanism of action of antiviral drugs suchFormula:C37H37F3N4O9Purity:Min. 95%Molecular weight:738.74 g/mol2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one
CAS:2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.Formula:C10H13N5O4Purity:Min. 95%Color and Shape:PowderMolecular weight:267.24 g/mol1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine
CAS:1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).Formula:C9H12ClN3O4Purity:Min. 95%Molecular weight:261.66 g/mol7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution
CAS:7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt is a nucleoside analog that inhibits telomerase. It binds to the catalytic subunit of telomerase, which is an RNA-dependent DNA polymerase that synthesizes telomeres during DNA replication. This binding prevents the enzyme from extending the 3' end of the DNA strand, inhibiting cell proliferation and leading to apoptosis. Telomerase inhibition has been shown to have an inhibitory effect on insulin resistance in mice. 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt also inhibits protein kinases, but does not inhibit phosphatases or other enzymes.Formula:C11H17N4O13P3·xLiPurity:Min. 95%Molecular weight:506.19 g/mol5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine
5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside analog that has antiviral, anticancer, and high purity properties. It is an activated nucleotide that can be incorporated into DNA or RNA. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a modified nucleoside with the deoxyribose sugar replaced by an isopropylidene group. This modification prevents the drug from being metabolized and excreted from the body. The drug is used to treat various cancers such as leukemia and lymphoma, as well as herpes simplex virus infections. It also has been shown to have antimicrobial properties against bacteria, fungi, and viruses.Formula:C12H15ClIN3O4Purity:Min. 95%Molecular weight:427.63 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite
CAS:2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of DNA. It can be used to treat AIDS, because it inhibits the reverse transcriptase enzyme. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite also has anticancer properties, which is due to its ability to inhibit RNA and protein synthesis in cancer cells. This compound has been synthesized by reacting 5'-O-DMT cytidine with methylacetoacetate under standard conditions. The modified nucleoside has a high purity, high quality, and novel structure.Formula:C47H64N7O7SiPurity:Min. 95%Molecular weight:867.14 g/mol7’-O-DMT-morpholino-5-methyluridine-N’-CE phosphoramidite
CAS:a morpholino amiditeFormula:C40H50N5O7PPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:743.83 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone
4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone is a novel nucleoside that has been modified by the addition of a 2'-deoxy, 3',5'-di-O-toluoyl group on the sugar moiety. This modification increases the stability of 4AMDT in serum and enhances its antiviral activity against DNA and RNA viruses. It also inhibits the proliferation of cancer cells and induces cell death by inhibiting protein synthesis.Formula:C29H29N5O6Purity:Min. 95%Molecular weight:543.57 g/mol2'-Deoxy-5-hydroxyuridine 5'-triphosphate
CAS:2'-Deoxy-5-hydroxyuridine 5'-triphosphate (doxorubicin) is a cytotoxic and chemotherapeutic agent that interferes with DNA replication. It is an oxidized form of the natural pyrimidine base thymine. The drug blocks DNA synthesis by preventing the incorporation of uracil into the newly synthesized strand, which causes strand breaks. Doxorubicin has been shown to be effective in treating a variety of cancers, including those of the breast, ovaries, bladder, and stomach. This drug can also cause severe side effects such as heart damage and hearing loss due to its interaction with cellular oxygen metabolism.Purity:Min. 95%6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine
CAS:6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside that is used as an anticancer and antiviral agent. It is synthesized from 9-(3',5'-di-O-benzoyl)-2'-deoxyribofuranosyl chloride, which is then chlorinated to form 6-chloro purine. This product has been shown to be active against human DNA tumor cells and other viruses in vitro. 6CPA, like other nucleosides, can be phosphorylated on the 3' or 5' position of the sugar moiety, yielding monophosphate or diphosphate derivatives respectively. The monophosphate derivative of 6CPA has a higher cytotoxicity than the diphosphate derivative. The deoxyribose sugar moiety canFormula:C24H18CIFN4O5Purity:Min. 95%Molecular weight:496.89 g/molThymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt
Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is a novel, modified nucleoside that is chemically synthesized from 2,3,4,6-tetraaminopyrimidine. It has antiviral activity and can be used to treat HIV infections. It is an active form of thymidine and inhibits the synthesis of viral DNA by blocking the activity of viral DNA polymerase in reverse transcription. This drug also exhibits anticancer activity by preventing cell proliferation and inducing apoptosis. Thymidine-5'-diphosphate-2-deoxy-D-glucose disodium salt is high purity with a CAS number of 63625-04-9.
Formula:C16H24N2O15P2Na2Purity:Min. 95%Molecular weight:592.29 g/mol3'-Azido-3'-deoxy-5-methylcytidine
CAS:3'-Azido-3'-deoxy-5-methylcytidine (AZDMC) is a novel nucleoside analog that inhibits viral replication. AZDMC is an activator of cellular DNA synthesis, which is essential for the replication of DNA and the production of RNA. It also has antiviral activity against influenza A and B viruses. The chemical name for AZDMC is 3'-azido-3'-deoxy-5-methylcytidine monophosphate (AMP). The CAS number for AZDMC is 1282040-14-5. It can be synthesized with high purity and quality by Ribonucleosides, Modified, Deoxyribonucleosides, Nucleosides, Phosphoramidites.
Purity:Min. 95%N6-Benzoyl-3'-deoxyadenosine
CAS:N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.Formula:C17H17N5O4Purity:Min. 95%Molecular weight:355.35 g/molAdenosine HCl
CAS:Adenosine is a nucleoside that is found in all cells. It plays an important role in the formation of ATP and as a neurotransmitter. Adenosine also acts on a receptor to promote vasodilation, improve cardiac contractility, and increase cardiac output. Adenosine has been found to be effective in preventing congestive heart failure in rats with myocardial infarction. In humans, adenosine has been shown to have beneficial effects on metabolic disorders such as diabetes mellitus and diabetic neuropathy. Adenosine HCl is an acid salt of adenosine that can be used for the treatment of coronary artery disease.Formula:C10H13N5O4·HClPurity:Min. 95%Molecular weight:303.7 g/mol2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-5-fluorouridine 3'-CE phosphoramidite is a nucleoside analogue that inhibits the growth of cancer cells. It is used in the synthesis of oligonucleotides, which are used as drugs to treat cancers. This product has high purity and good quality and has been shown to be effective against cancer cells.
Formula:C39H46FN4O8PPurity:Min. 95%Color and Shape:PowderMolecular weight:748.8 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine-3'-O-succinate triethylammonium salt
N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine-3'-O-succinate triethylammonium salt is a synthetic nucleoside. It is used for the treatment of HIV infection. N4-Benzoyl-1-(2'-deoxy-5'-O-DMT)-2'-fluoro -b -D -arabinofuranosyl) -5 methylcytosine (ADT) inhibits viral replication by inhibiting the activity of reverse transcriptase, which is an enzyme that synthesizes DNA from RNA. ADT is activated to its active form by phosphorylation with a kinase and then converted to diphosphate ADP by the enzyme pyrophosphatase. ADP then acts as a substrate for DNA polymerases, incorporating into newly synthesized DNA
Formula:C42H40FN3O10·C6H16NPurity:Min. 95%Molecular weight:868 g/mol2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine
CAS:2'-Deoxy-8-(9H-fluoren-2-ylamino)-guanosine (FdA) is a synthetic nucleoside that was designed for use as a dietary supplement to inhibit carcinogenesis. It is an analog of guanosine and is phosphorylated by cellular kinases to form 2'-deoxy-8-(9H-fluoren-2-ylamino)-inosine monophosphate. FdA inhibits the process of DNA replication in mammalian cells, which may be due to its ability to bind single stranded DNA. This drug has been shown to reduce the mutation frequency and increase the life span of mice with bladder cancer.Formula:C23H22N6O4Purity:Min. 95%Molecular weight:446.46 g/mol6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione
CAS:6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione is a nucleoside analog that has shown to be an activator of the ribonucleotide reductase enzyme. It has also been shown to have anticancer activity. 6-(4-Iodobenzyl)-1-Methyl Pyrimidine-2,4-(1H,3H)-Dione inhibits DNA synthesis by binding to the DNA molecule at the site of incorporation and preventing its duplication. This compound also inhibits RNA synthesis by binding to the RNA molecule at the site of incorporation and preventing its duplication. It has been shown to inhibit cancer cell growth in culture and can be used as a chemotherapeutic agent.Formula:C12H11IN2O2Purity:Min. 95%Molecular weight:342.13 g/mol2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde
CAS:2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde is a modified nucleoside that has been shown to be an effective antiviral and anticancer agent. This compound inhibits viral replication by blocking the synthesis of viral DNA, and also exhibits cytotoxic activity against cancer cells. 2-(2-Methoxyethyl)pyrimidine-5-carbaldehyde is an activator of ribonucleotide reductase and deoxyribonucleotide reductase and can be used in the synthesis of nucleosides, DNA, or phosphoramidites.Formula:C8H10N2O2Purity:Min. 95%Molecular weight:166.18 g/molDihydrozeatin riboside-5'-monophosphate sodium salt
CAS:Dihydrozeatin riboside-5'-monophosphate sodium salt is a cytokinin that belongs to the group of indole compounds. It has been shown to inhibit the biosynthesis of ethylene, which prevents fruit from ripening. Dihydrozeatin riboside-5'-monophosphate sodium salt is also able to inhibit the synthesis of adenosine, another plant hormone that inhibits growth and promotes dormancy in plants. The bioassay for this product has been done with amanita muscaria, an edible mushroom found in North America and Europe. This mushroom contains dihydrozeatin as well as other related compounds such as zeatin, which can be converted into dihydrozeatin by enzymes present in the intestines. The symptoms of poisoning by this mushroom include vomiting and diarrhea, owing to its effects on intestinal motility.Formula:C15H22N5Na2O8P·H2OPurity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:495.33 g/mol5’-O-DMT cET-N6-benzoyladenosine 3’-OCE amidite
CAS:Please enquire for more information about 5'-ODMT cEt N-Bz A Phosphoramidite including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C49H54N7O8PMolecular weight:899.97 g/mol8-Oxo-7-thioguanosine
CAS:8-Oxoguanosine monophosphate (8-oxoGMP) is a synthetic nucleoside that is activated by the enzyme thioredoxin reductase and phosphorylated to form 8-oxoGTP. The anticancer activity of 8-oxoGMP is due to its ability to inhibit ribonucleotide reductase, which reduces the production of DNA and RNA in cells. This product has been shown to inhibit HIV replication in vitro and in vivo. It also inhibits viral replication by inhibiting the synthesis of viral nucleic acids such as DNA, RNA, and deoxyribonucleic acid (DNA).Formula:C10H12N4O6SPurity:Min. 95%Color and Shape:PowderMolecular weight:316.29 g/mol3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine
CAS:3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine is a nucleoside derivative that has antiviral activity. It is synthesized by the condensation of 2,3,5-trihydroxybenzoic acid with 3'-chloro-5'-fluoroacetophenone in the presence of pyridine and triethylamine. The nucleoside has been shown to be an effective inhibitor of HIV replication in vitro. 3',5'-Di-O-p-chlorobenzoyl-2'-deoxy-5-fluorouridine also inhibits DNA synthesis in human lymphocytes at concentrations of 5 μM or less. This compound can be used as an activator for DNA polymerases and phosphoramidites for DNA synthesis.Formula:C23H17Cl2FN2O7Purity:Min. 95%Molecular weight:523.29 g/mol3',5'-Di-O-acetyl-N2-acetyl-O6-diphenylcarbamoyl-2'-deoxy-D-guanosine
3',5'-Di-O-acetyl-N2-acetyl-O6-diphenylcarbamoyl-2'-deoxy-D-guanosine is a synthetic nucleoside that has been modified with an acetyl group at the 3' and 5' positions of the sugar. It has antiviral, anticancer, and antiretroviral activities against HIV. This nucleoside has also been shown to inhibit human leukemia cells in vitro by binding to DNA, inhibiting its synthesis. The drug is currently undergoing clinical trials for the treatment of AIDS patients.Purity:Min. 95%2'-Deoxyguanosine-5'-monophosphate free acid
CAS:2'-Deoxyguanosine-5'-monophosphate free acid (dGMP) is a nucleotide that can be used as a substrate to measure the activity of protein kinase C. It is also a precursor in DNA synthesis, and its incorporation into DNA is catalyzed by polymerase chain reaction. 2'-Deoxyguanosine-5'-monophosphate free acid has been shown to inhibit transcriptional regulation, which may be related to its interaction with nuclear DNA. Furthermore, it has been shown to have an antioxidant effect due to its ability to donate electrons. 2'-Deoxyguanosine-5'-monophosphate free acid has also been shown to react with sodium salts in plasma mass spectrometry experiments, and titration calorimetry experiments have shown that it reacts with calcium ions in vitro.br>Formula:C10H14N5O7PPurity:Min. 95%Molecular weight:347.22 g/mol3'-Amino-2',3'-dideoxy-2-fluoroadenosine
3'-Amino-2',3'-dideoxy-2-fluoroadenosine is a novel compound that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It also has antiviral and anticancer activities. 3'-Amino-2',3'-dideoxy-2-fluoroadenosine has high purity and high quality and can be used as an activator for phosphoramidite synthesis.Formula:C10H13FN6O2Purity:Min. 95%Color and Shape:PowderMolecular weight:268.25 g/mol8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate Sp-isomer sodium
CAS:8-(4-Chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt (8-chloro-GTP) is a modified nucleoside that inhibits the synthesis of DNA by preventing the addition of nucleotides to the 3' end of DNA. It is an antiviral and anticancer agent, and can be used as a phosphoramidite in the synthesis of DNA. 8-chloro-GTP has shown high purity and high quality in synthesized DNA. Research on this compound is still ongoing, but it has been shown to be novel and modified compared to other nucleosides.Formula:C16H14ClN5O6PS2•NaPurity:Min. 95%Molecular weight:525.86 g/mol5-Methyl-4’-thiocytidine
CAS:5-Methyl-4’-thiocytidine is an antiviral agent that has been shown to be effective against herpes simplex virus (HSV) type 1 and 2. 5-Methyl-4’-thiocytidine inhibits viral replication by competing with deoxyribonucleosides for incorporation into the viral DNA, which leads to the synthesis of defective DNA. This drug also has anticancer properties and is used in the treatment of leukemia, lymphoma, and carcinomas. 5-Methyl-4’-thiocytidine is a novel monophosphate nucleoside that can be used as an activator for phosphoramidite synthesis. The CAS number for this compound is 1312295-87-6. Synthesis of 5-methyl 4’ thiocytidine requires high purity, high quality nucleosides, and a novel phosphoramidite synthesis procedure.Purity:Min. 95%2-Amino-6-chloro-7-methyl-9-(b-D-ribofuranosyl)purine
CAS:2-Amino-6-chloro-7-methyl-9-(b-D-ribofuranosyl)purine is a nucleoside which is the structural analog of adenosine and is used in the synthesis of DNA, RNA, and other nucleosides. It has antiviral activity against herpes simplex virus type 1 and 2, Epstein Barr virus, poliovirus types 1, 2, and 3, and vesicular stomatitis virus. This compound also has anticancer activity. 2-Amino-6-chloro-7-methyl-9-(b-D ribofuranosyl) purine can be used to synthesize deoxyribonucleosides or monophosphate nucleotides. It can also be used as an intermediate for phosphoramidites in the synthesis of DNA or RNA.Formula:C11H16ClN5O4Purity:Min. 95%Molecular weight:317.73 g/mol2'-Deoxy-5'-O-DMT-guanosine
CAS:2'-Deoxy-5'-O-DMT-guanosine is a purine nucleoside that is converted to 2'-deoxy-5'-O-DMT-adenosine by the enzyme deoxyadenosyltransferase. This conversion is necessary for the synthesis of adenosylcobalamin, which is essential for the methylation of homocysteine to methionine. 2'-Deoxy-5'-O-DMT-guanosine has been shown to have cancer chemopreventive effects in vitro and in vivo. It also has been shown to enhance dna hybridization and hydrophobic interactions with cancerous cells, which may be due to its ability to inhibit gene expression.
Formula:C31H31N5O6Purity:Min. 95%Molecular weight:569.61 g/mol5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile
CAS:5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile is a nucleoside phosphoramidite that is synthesized from 2'-deoxyribose, 5'-iodoimidazole and triacetic acid. This compound is a novel phosphoramidite and can be used to synthesize DNA or RNA molecules. It has been shown to have anticancer properties, which may be due to its ability to inhibit DNA replication. 5-Iodo-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazo-4-carbonitrile also has antiviral properties and can be used as an activator in the synthesis of modified nucleosides.Formula:C15H16IN3O7Purity:Min. 95%Molecular weight:477.21 g/mol5'-O-DMT-thymidine 3'-O-[(S-acetyl-6-thiohexyl) N,N-diisopropylphosphoramidite
5'-O-DMT-thymidine 3'-O-[(S-acetyl-6-thiohexyl) N,N-diisopropylphosphoramidite] is a novel compound that has been modified to enhance antiviral activity and provide protection against influenza virus. The phosphoramidite monophosphate is prepared by coupling of the 5'-O-DMT-thymidine 3'-O-[(S-acetyl-6-thiohexyl) N,N-diisopropylphosphoramidite] with an appropriate nucleoside phosphorylating agent, such as a thiophosphorylating agent. This product has high purity and quality.Purity:Min. 95%(5'S)-2'-Deoxy-8,5'-cycloadenosine
CAS:(5'S)-2'-Deoxy-8,5'-cycloadenosine is a nucleoside analog that blocks the synthesis of DNA. It is a glycosylated nucleoside that contains an 8-carbon fatty acid chain linked to the 5’ carbon of the sugar ring. This compound is formed from the reaction of (5'S)-2'-deoxyadenosine and dicyclohexylcarbodiimide. The biological properties of this drug are not well understood, but it has been shown to be reactive with physiological levels and able to induce neuronal death in an experimental model. The mechanism for this effect is unknown, but may involve intramolecular hydrogen bonding or hydrolysis by esterases. A molecular docking analysis was performed to study the binding affinity between (5'S)-2'-deoxy-8,5'-cycloadenosine and human mda-mb-231 breast cancer cells. This analysis showed that wild
Formula:C10H11N5O3Purity:Min. 95%Molecular weight:249.23 g/mol2-tert-Butylpyrimidine-5-carbaldehyde
CAS:2-tert-Butylpyrimidine-5-carbaldehyde (2BP) is a potent, selective inhibitor of DNA polymerase that is expressed in the tibia during bone development. 2BP has been shown to inhibit platelet-derived growth factor (PDGF)-induced angiogenesis in mouse calvaria and animal research models. This compound also inhibits the proliferation of basic fibroblasts and cancer cells in vitro.Formula:C9H12N2OPurity:Min. 95%Molecular weight:164.2 g/mol3'-O-Azidomethyl 2'-deoxyadenosine 5'-O-triphosphate sodium salt
3'-O-Azidomethyl 2'-deoxyadenosine 5'-O-triphosphate sodium salt (3'AADAP) is a novel nucleotide analog that has been shown to have antiviral and anticancer activities. It is a high-quality, purified nucleotide that can be used as an activator for DNA synthesis. 3'AADAP can also be used to synthesize deoxyribonucleosides, which are modified nucleotides that have the ability to inhibit replication of RNA viruses such as HIV. The CAS number for 3'AADAP is 72295-72-8.Formula:C11H17N8O12P3Purity:Min. 95%Molecular weight:546.22 g/mol5'-ODMT-thymidine 3'-Sp-oxazaphospholidine
5'-ODMT-thymidine 3'-Sp-oxazaphospholidine is a modified nucleoside that can be used as an anticancer drug. It is a high purity, diphosphate, Anticancer, Modified, Phosphoramidites. 5'-ODMT-thymidine 3'-Sp-oxazaphospholidine is synthesized by the phosphorylation of thymidine with oxazaphospholidine. It has been shown to inhibit DNA and RNA synthesis in cancer cells.
Purity:Min. 95%2-Benzylthio-6-chloropurine
CAS:2-Benzylthio-6-chloropurine is a synthetic nucleoside analogue that is an antiviral agent. It inhibits the synthesis of viral DNA by competitive inhibition of thymidine kinase, which is an enzyme necessary for the conversion of deoxyribonucleotides to their monophosphate form. 2-Benzylthio-6-chloropurine has been found to be effective against herpes simplex virus 1 and 2 (HSV1 and HSV2). The drug is also active against HIV, influenza A virus, and cytomegalovirus.Formula:C15H9CIN4SPurity:Min. 95%Molecular weight:416.24 g/mol4-(2-Methoxyethylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid
CAS:4-(2-Methoxyethylamino)-2-(methylthio)pyrimidine-5-carboxylic acid (4MEAP) is a novel phosphoramidite that can be used in the synthesis of ribonucleosides and deoxyribonucleosides. 4MEAP has antiviral activity, cytotoxicity, and anticancer properties. It may also have potential as an anti-inflammatory agent due to its ability to inhibit prostaglandin production.Formula:C9H13N3O3SPurity:Min. 95%Molecular weight:243.28 g/mol1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino-1,3-dihydro-2-oxo-1,3,5-triazine
1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino-1,3-dihydro-2-oxo-1,3,5-triazine is a nucleoside that is used as an anticancer drug. It is a modified nucleotide with a 2'-deoxyribofuranosyl group attached to the 3' carbon of the sugar moiety. It has been shown to be active against viruses and cancer cells. 1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino -1,3 -dihydro -2 -oxo -1,3,5 -triazine inhibits the replication of DNA by inhibiting DNA polymerase. This in turn prevents RNA synthesis and protein synthesis.Formula:C24H24N4O6Purity:Min. 95%Molecular weight:464.48 g/mol1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, lithium salt
1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate, lithium salt (ABIPT) is a modified nucleotide that has antiviral and anticancer activities. It is an activator of the ribonucleoside diphosphate reductase enzyme and can be used to treat viral diseases such as HIV and hepatitis C. ABIPT also has anticancer activity by inhibiting DNA synthesis in tumor cells and inducing apoptosis. This drug is a novel monophosphate nucleoside that has been shown to inhibit the replication of influenza virus in vitro.Purity:Min. 95%1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N6-benzoyladenin-1-yl)-D-altro-hexitol
CAS:1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N6-benzoyladenin-1)-yl)-D-altrohexitol is a novel anticancer and antiviral agent. It is a phosphoramidate nucleotide analog that inhibits viral replication by blocking the synthesis of viral DNA. It also has an inhibitory effect on cancer cells, which may be due to its ability to activate natural killer cells or cytotoxic T lymphocytes.Formula:C32H27N5O6Purity:Min. 95%Color and Shape:SolidMolecular weight:577.6 g/mol3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT-adenosine
CAS:3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT-adenosine is a nucleoside with a novel chemical structure. It is a deoxyribonucleoside monophosphate, which has antiviral and anticancer properties. 3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT-adenosine inhibits the formation of diphosphate from ATP, which prevents DNA and RNA synthesis in cells. This drug also binds to the enzyme ribonuclease, preventing the breakdown of RNA. The phosphoramidites used for synthesizing 3'-O-tert-Butyldimethylsilyl-2'-deoxy-5'-O-DMT adenosine are of high quality and can be used for making other nucleosides.Formula:C37H45N5O5SiPurity:Min. 95%Molecular weight:667.87 g/molAdenosine-5'-O-diphospho-(1''-(4-nitrophenoxy)-ribose) sodium
CAS:Adenosine-5'-O-diphospho-(1''-(4-nitrophenoxy)-ribose) sodium is a nucleic acid analog that is used in antiviral, anticancer, and gene therapy. It is a modified nucleotide with a phosphoramidite group at the 5' position. The phosphoramidite group is used for the synthesis of DNA or RNA. It has been shown to activate cellular processes such as transcription, translation, and replication in vitro. This compound also inhibits cancer cell growth in vivo and has been shown to be effective against bacterial infections caused by Mycobacterium tuberculosis and Mycobacterium avium complex.Formula:C21H26N6O16P2·xNaPurity:Min. 95%Molecular weight:680.41 g/mol3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine
CAS:3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is a novel synthetic nucleoside. It is an intermediate in the synthesis of phosphoramidites and has been used in the synthesis of oligonucleotides and DNA. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine can also be used as antiviral and anticancer agents. 3',5'-Bis-O-(tert-butyldimethylsilyl)-5-bromo-2'-deoxyuridine is soluble in water, ethanol, and chloroform at a concentration of 1 g/L. The purity of this product is greater than 98%.Formula:C21H39BrN2O5Si2Purity:Min. 95%Molecular weight:535.62 g/mol2',3',5'-Tri-O-acetylcytidine HCl
CAS:2',3',5'-Tri-O-acetylcytidine HCl is a modified nucleoside that has been shown to have anticancer activity. The cytotoxic effect of 2',3',5'-tri-O-acetylcytidine HCl is mediated by its ability to inhibit DNA synthesis, which leads to cell death. This agent also inhibits viral replication and may be useful in the treatment of herpes virus infections. 2',3',5'-tri-O-acetylcytidine HCl is a stable nucleoside analog that can be used as an activator for polyphosphate polymerase or as a building block for the preparation of phosphoramidites, which are intermediates in the synthesis of oligonucleotide sequences.Formula:C15H19N3O8·HClPurity:Min. 95%Molecular weight:405.79 g/mol4-Chloro-6-imidazol-1-yl-pyrimidine
CAS:4-Chloro-6-imidazol-1-yl-pyrimidine is a quaternary ammonium compound that can be used to make antireflection coatings. It has been shown to have a high degree of compatibility with polymers, such as allyl carbonate, which are used in functional groups. 4-Chloro-6-imidazol-1-yl-pyrimidine has also been shown to react with stannous octoate, and the reaction time is dependent on the concentration of both compounds. This molecule has been found to be biodegradable and liquid crystal compositions can be made from it by changing the ratio of molecules to liquid crystals. 4-Chloro-6-imidazol-1-yl pyrimidine reacts with hydroxyl groups in epoxy resins and diolefinic hydrocarbons, forming crosslinks in sealants or coatings. The sealantFormula:C7H5ClN4Purity:Min. 95%Molecular weight:180.59 g/molLamivudine 5'-diphosphate ammonium salt
CAS:Lamivudine is a monophosphate antiviral drug that inhibits the synthesis of DNA. It has been shown to inhibit the replication of human immunodeficiency virus-1 (HIV-1) in vitro, and to protect monkeys from simian acquired immune deficiency syndrome (SAIDS). Lamivudine 5'-diphosphate ammonium salt is an antiviral agent that belongs to the group of deoxyribonucleosides. It has been shown to be effective against HIV-1 and SAIDS in animals. The mechanism of action is not fully understood, but it may work by inhibiting viral RNA synthesis or by preventing viral DNA integration into host cell DNA.
Formula:C8H19N5O9P2SPurity:Min. 95%Molecular weight:423.28 g/mol1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol
1,5-Anhydro-2,3-dideoxy-2-(N6-benzoyladenin-1-yl)-D-glucitol is a novel modified nucleoside that is used as an activator in the synthesis of oligodeoxynucleotides and ribonucleosides. It is also used for the synthesis of phosphoramidites for DNA and RNA molecules. This product is available in high purity and quality.Formula:C18H19N5O4Purity:Min. 95%Molecular weight:369.38 g/mol2-Amino-4-(4-methoxyphenyl)pyrimidine
CAS:2-Amino-4-(4-methoxyphenyl)pyrimidine (AMP) is a synthetic nucleoside analog. It has antiviral activity and is used for the treatment of hepatitis B virus infection. AMP inhibits viral DNA polymerase and prevents the synthesis of viral DNA and RNA. It has been modified to include a methoxy group at the 4 position, which provides additional stability against the enzyme ribonuclease. AMP is also an activator of ribonucleotide reductase and can be used as a substrate to synthesize deoxyribonucleosides, phosphoramidites, diphosphate, or monophosphate nucleotides for DNA synthesis.
AMP has CAS number 99844-02-7 and is available in high purity.Formula:C11H11N3OPurity:Min. 95%Molecular weight:201.22 g/molN6-Benzoyl-7-deaza-2'-deoxyadenosine
CAS:N6-Benzoyl-7-deaza-2'-deoxyadenosine is a novel synthetic monophosphate activator that can be used to induce cell death in cancer cells. It is structurally similar to the natural nucleotide adenosine, and it binds to the same receptors on cells as adenosine. N6-Benzoyl-7-deaza-2'-deoxyadenosine has been shown to inhibit viral replication by interfering with DNA synthesis and RNA transcription, which are essential for viral reproduction.Formula:C18H18N4O4Purity:Min. 95%Molecular weight:354.36 g/mol2-Amino-2'-deoxyadenosine 5'-triphosphate
CAS:2-Amino-2'-deoxyadenosine 5'-triphosphate (2ADP) is a nucleotide that is involved in the synthesis of DNA. It is an important part of the process of DNA replication, as it provides the necessary energy to drive reactions that synthesize new DNA strands. It also has anti-viral properties and can be used as a molecular probe to detect acid. 2ADP is detectable with most common detection methods, such as UV/visible absorbance spectroscopy, fluorescence spectroscopy, and chemiluminescence. It is one of the three triphosphates found in cells and can be used to polymerize RNA by adding ribose phosphate groups to the sugar molecule in RNA. This reaction requires ATP, which produces AMP, ADP, and 2ADP.Formula:C10H17N6O12P3Purity:Min. 95%Molecular weight:506.2 g/mol5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA)
5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) is a nucleoside that belongs to the group of modified nucleosides. It is used as an activator for phosphoramidite synthesis and as an antiviral agent. 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) has been shown to have anticancer activity by inhibiting DNA, RNA, and protein synthesis in tumor cells and also stimulating apoptosis. 5'-O-DMT-uridine 3'-succinyl CPG 1000 Å (RNA) is synthesized from uracil, which is obtained by the hydrolysis of thymine or cytosine. This product is available with a high quality at a competitive price.Purity:Min. 95%2’-O,4’-C-Methylenecytidine
CAS:2’-O,4’-C-Methylenecytidine is a nucleoside that has been used to synthesize oligonucleotides. It has been shown to form duplexes with complementary DNA and RNA strands. 2’-O,4’-C-Methylenecytidine forms bicyclic analogues with high efficiency and can be used as an n-type structural probe.Purity:Min. 95%2’-Deoxy-8-methylthioadenosine
CAS:2’-Deoxy-8-methylthioadenosine is a monophosphate and antiviral compound. It is used for the treatment of viral infections and has been shown to be active against herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus, and human immunodeficiency virus. The compound inhibits the activity of DNA polymerase by competing with deoxyribonucleosides as substrates. This results in the inhibition of DNA synthesis. 2’-Deoxy-8-methylthioadenosine also inhibits ribonucleotide reductase, which is an enzyme that catalyzes the production of ribonucleotides from deoxyribonucleotides. 2’-Deoxy-8-methylthioadenosine has been shown to inhibit cell proliferation in vitro and in vivo through G2/M phase arrest and apoptosis induction.Purity:Min. 95%3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine
CAS:3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is an anticancer drug that inhibits the growth of cells by preventing DNA synthesis. It is a modified nucleoside that is synthesized from thymidine and has been shown to have antiviral and anti-inflammatory properties. 3'-o-(t-Butyldimethylsilyl)-5'-deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is also used in the production of phosphoramidites and ribonucleotides.Formula:C30H40N4O4SiPurity:Min. 95%Molecular weight:548.7 g/molN5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å
N5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å is a modified nucleoside that is used for the synthesis of DNA and RNA. It is an activator of antiviral and anticancer drugs. N5-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-succinyl CPG 500 Å has been shown to be an effective cancer treatment agent in vivo, as well as an inhibitor of viral replication. It can also be used in the synthesis of nucleosides and phosphoramidites.Purity:Min. 95%Color and Shape:Powder3’-O-tert-Butyldiphenylsilylthymidine
CAS:Used as a protected thymidine nucleoside in chemical synthesis, specifically as an intermediate in the preparation of other thymidine derivatives, particularly 5'-modified nucleosides and oligonucleotides. The tert-butyldiphenylsilyl (TBDPS) group is a silyl protecting group selectively attached to the 3' hydroxyl group of thymidine.Formula:C26H32N2O5SiPurity:Min. 95%Color and Shape:White PowderMolecular weight:480.63 g/molL-5-methyluridine
CAS:L-5-methyluridine is a nucleoside that is used as a building block in the synthesis of oligonucleotides. It contains one ribose sugar and one deoxyribose sugar, linked to the base adenine by a phosphate group. L-5-methyluridine can be synthesized from 5-chloro-2'-deoxyadenosine, hypoxanthine, and ammonium chloride. The synthesis starts with condensation reactions between the two sugar molecules to form an intermediate called a nucleoside. This is followed by alkylation of the base and then oxidation of the sugar group to form anomeric esters. The last step involves hydrolysis of the acyloxy ester, which yields L-5-methyluridine after acidification.Formula:C10H14N2OPurity:Min. 95%Molecular weight:178.23 g/mol2'-Deoxy-5'-S-DMT-5'-thioinosine 3'-CE phosphoramidite
2'-Deoxy-5'-S-DMT-5'-thioinosine 3'-CE phosphoramidite is a novel nucleoside analogue that has antiviral activity. It can be synthesized from 2'-deoxyribonucleosides and 5'-thioinosine monophosphate. This compound inhibits viral replication by inhibiting the synthesis of viral diphosphate, which is required for DNA synthesis. The compound also has anticancer properties and can inhibit the growth of tumor cells by blocking the process of DNA synthesis.Purity:Min. 95%2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt - 100 mM aqueous solution
CAS:2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt is a circularization agent that can be used in the efficient method for the synthesis of DNA. It inhibits the growth of bacteria by binding to their DNA and preventing transcription. 2'-Deoxyadenosine-5'-O-(1-thiotriphosphate) lithium salt has shown inhibitory effects against tuberculosis and other infectious diseases, including diphtheria, tetanus, typhoid fever, and malaria. This drug also prevents the replication of viral RNA. The inhibition occurs through an analog mechanism at the level of nucleic acid synthesis or polymerase chain reaction (PCR). The thiophosphate group is cleaved from the triphosphate moiety in the presence of metal ions such as Zn2+, Mg2+, Mn2+, or Ca2+. The active form is enzymatically hydrolyzed by covalent enzyme activity toFormula:C10H16N5O11P3S·xLiPurity:Min. 95%Molecular weight:507.25 g/molN-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-O-(2-methoxyethyl)adenosine
CAS:N-Benzoyl-5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-O-(2-methoxyethyl)adenosine is a synthetic nucleoside that is an activator of DNA polymerase and has antiviral activities. It is also used in the synthesis of deoxyribonucleosides, phosphoramidites, and ribonucleosides.Formula:C41H41N5O8Purity:Min. 95%Color and Shape:White PowderMolecular weight:731.79 g/molAristeromycin
CAS:Carbocyclic nucleoside antibioticFormula:C11H15N5O3Purity:Min. 95%Molecular weight:265.27 g/mol2',3',5'-Tri-O-acetyl-5-methyluridine
2',3',5'-Tri-O-acetyl-5-methyluridine is a nucleoside that is used as a substrate for the enzyme, methylmagnesium (MeMg) nucleotides. It has been shown to have a high basicity and is a good substrate for the enzyme, MeMg nucleotides. 2',3',5'-Tri-O-acetyl-5-methyluridine also has stereoselectivity and can be synthesized with high purity.Purity:Min. 95%2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate
2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is a modified nucleotide analog that is used as an antiviral agent. It inhibits the synthesis of viral DNA by competitively inhibiting the incorporation of deoxyribonucleoside triphosphates into the growing DNA chain. 2-Amino-6-chloro-(b-D-ribofuranosyl)purine-5'-triphosphate is phosphorylated to 2-[2-(2,6,8,10,12,14,16,-doxohexadecyl)-1H--imidazo[4,5--c]pyridine--1--carboxylic acid]ethanol phosphate in vivo and this active form inhibits human immunodeficiency virus type 1 (HIV1) replication in vitro with an IC 50 of 0.06 μM.Formula:C10H15ClN5O13P3Purity:Min. 95%Molecular weight:541.63 g/mol1-(b-D-Xylofuranosyl)cytosine
CAS:1-(b-D-Xylofuranosyl)cytosine is a nucleoside analog that is used in the treatment of cancer. It inhibits DNA replication by binding to the RNA template strand and blocking the incorporation of cytosine. 1-(b-D-Xylofuranosyl)cytosine has been shown to have an inhibitory effect on tumor cell lines, with a thermal expansion coefficient similar to biphenyl. The molecular weight of 1-(b-D-xylofuranosyl)cytosine is approximately 244 g/mol, which is greater than that of water (18 g/mol). 1-(b-D-xylofuranosyl)cytosine also binds to double stranded DNA with high affinity, leading to inhibition of protein synthesis and cell division. In addition, this compound has been shown to bind to naphthalene and form adducts with its hydroxyl groups.Formula:C9H13N3O5Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:243.22 g/mol
![2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FPD138044.webp&w=3840&q=75)
![5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FND08236.webp&w=3840&q=75)
![2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNA145593.webp&w=3840&q=75)
